Conservation of cofitness between OKFHMN_10730 and OKFHMN_18090 in Escherichia coli ECRC100

68 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC100 1.0 OKFHMN_10730 leuD 3-isopropylmalate dehydratase small subunit 1.0 OKFHMN_18090 argG argininosuccinate synthase 0.97 3
Escherichia coli ECRC98 1.00 JDDGAC_14325 leuD 3-isopropylmalate dehydratase small subunit 1.00 JDDGAC_21715 argG argininosuccinate synthase 0.86 37
Escherichia coli ECRC102 1.00 NIAGMN_08580 leuD 3-isopropylmalate dehydratase small subunit 1.00 NIAGMN_15850 argG argininosuccinate synthase — —
Escherichia coli ECRC99 1.00 KEDOAH_17425 leuD 3-isopropylmalate dehydratase small subunit 1.00 KEDOAH_10060 argG argininosuccinate synthase — —
Escherichia coli ECRC101 1.00 MCAODC_01245 leuD 3-isopropylmalate dehydratase small subunit 1.00 MCAODC_08610 argG argininosuccinate synthase 0.90 33
Escherichia coli BL21 0.99 ECD_00073 3-isopropylmalate dehydratase small subunit 1.00 ECD_03038 argininosuccinate synthetase 0.80 41
Escherichia coli ECOR27 0.99 NOLOHH_03075 leuD 3-isopropylmalate dehydratase small subunit 1.00 NOLOHH_09890 argG argininosuccinate synthase 0.86 42
Escherichia coli ECRC62 0.99 BNILDI_08535 leuD 3-isopropylmalate dehydratase small subunit 1.00 BNILDI_01645 argG argininosuccinate synthase 0.91 50
Escherichia coli BW25113 0.99 b0071 leuD isopropylmalate isomerase small subunit (NCBI) 1.00 b3172 argG argininosuccinate synthase (NCBI) 0.90 41
Escherichia coli Nissle 1917 0.99 ECOLIN_RS00385 3-isopropylmalate dehydratase small subunit 1.00 ECOLIN_RS18275 argininosuccinate synthase 0.88 12
Escherichia fergusonii Becca 0.99 EFB2_03974 3-isopropylmalate dehydratase small subunit 1.00 EFB2_00651 Argininosuccinate synthase low > 86
Escherichia coli ECOR38 0.99 HEPCGN_08710 leuD 3-isopropylmalate dehydratase small subunit 1.00 HEPCGN_16965 argG argininosuccinate synthase 0.92 11
Escherichia coli HS(pFamp)R (ATCC 700891) 0.98 OHPLBJKB_03586 3-isopropylmalate dehydratase small subunit 1.00 OHPLBJKB_00528 Argininosuccinate synthase low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.92 GFF167 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.97 GFF2913 Argininosuccinate synthase (EC 6.3.4.5) low > 78
Enterobacter sp. TBS_079 0.89 MPMX20_00766 3-isopropylmalate dehydratase small subunit 1 0.95 MPMX20_04077 Argininosuccinate synthase 0.83 40
Enterobacter asburiae PDN3 0.89 EX28DRAFT_3667 3-isopropylmalate dehydratase, small subunit 0.94 EX28DRAFT_3224 argininosuccinate synthase (EC 6.3.4.5) 0.78 21
Klebsiella michiganensis M5al 0.87 BWI76_RS04665 3-isopropylmalate dehydratase small subunit 0.95 BWI76_RS25115 argininosuccinate synthase 0.91 26
Dickeya dadantii 3937 0.83 DDA3937_RS18130 3-isopropylmalate dehydratase small subunit 0.92 DDA3937_RS20890 argininosuccinate synthase 0.65 61
Rahnella sp. WP5 0.83 EX31_RS03695 3-isopropylmalate dehydratase small subunit 0.90 EX31_RS13445 argininosuccinate synthase 0.97 6
Dickeya dianthicola ME23 0.82 DZA65_RS19215 3-isopropylmalate dehydratase small subunit 0.92 DZA65_RS00355 argininosuccinate synthase 0.65 60
Dickeya dianthicola 67-19 0.82 HGI48_RS18070 3-isopropylmalate dehydratase small subunit 0.92 HGI48_RS00355 argininosuccinate synthase 0.76 22
Pectobacterium carotovorum WPP14 0.80 HER17_RS03070 3-isopropylmalate dehydratase small subunit 0.93 HER17_RS21055 argininosuccinate synthase low > 75
Serratia liquefaciens MT49 0.80 IAI46_03340 3-isopropylmalate dehydratase small subunit 0.15 IAI46_24505 argininosuccinate synthase low > 86
Erwinia tracheiphila SCR3 0.72 LU632_RS02865 leuD 3-isopropylmalate dehydratase small subunit 0.16 LU632_RS19605 argininosuccinate synthase 0.85 5
Pseudomonas sp. RS175 0.63 PFR28_02823 3-isopropylmalate dehydratase small subunit 1 0.12 PFR28_03353 Argininosuccinate synthase — —
Pseudomonas putida KT2440 0.63 PP_1986 3-isopropylmalate dehydratase small subunit 0.12 PP_1088 Argininosuccinate synthase 0.78 26
Pseudomonas fluorescens SBW25 0.63 PFLU_RS20575 3-isopropylmalate dehydratase small subunit 0.11 PFLU_RS05725 argininosuccinate synthase — —
Pseudomonas fluorescens SBW25-INTG 0.63 PFLU_RS20575 3-isopropylmalate dehydratase small subunit 0.11 PFLU_RS05725 argininosuccinate synthase — —
Pseudomonas sp. S08-1 0.62 OH686_04475 3-isopropylmalate dehydratase small subunit 0.12 OH686_03930 argininosuccinate synthase 0.65 37
Pseudomonas stutzeri RCH2 0.61 Psest_2590 3-isopropylmalate dehydratase, small subunit 0.12 Psest_3121 argininosuccinate synthase — —
Shewanella loihica PV-4 0.61 Shew_3469 isopropylmalate isomerase small subunit (RefSeq) 0.15 Shew_0205 argininosuccinate synthase (RefSeq) 0.98 2
Ralstonia solanacearum PSI07 0.58 RPSI07_RS14700 3-isopropylmalate dehydratase small subunit 0.77 RPSI07_RS12120 argininosuccinate synthase — —
Shewanella sp. ANA-3 0.58 Shewana3_3758 leuD isopropylmalate isomerase small subunit (RefSeq) 0.13 Shewana3_3902 argininosuccinate synthase (RefSeq) 0.88 56
Herbaspirillum seropedicae SmR1 0.58 HSERO_RS16505 3-isopropylmalate dehydratase small subunit 0.79 HSERO_RS07180 argininosuccinate synthase — —
Shewanella oneidensis MR-1 0.58 SO4233 leuD 3-isopropylmalate dehydratase, small subunit (NCBI ptt file) 0.14 SO0278 argG argininosuccinate synthase (NCBI ptt file) 0.95 27
Variovorax sp. SCN45 0.58 GFF3889 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.77 GFF3096 Argininosuccinate synthase (EC 6.3.4.5) — —
Paraburkholderia bryophila 376MFSha3.1 0.58 H281DRAFT_06073 3-isopropylmalate dehydratase, small subunit 0.13 H281DRAFT_04120 argininosuccinate synthase 0.59 14
Hydrogenophaga sp. GW460-11-11-14-LB1 0.58 GFF3361 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.76 GFF294 Argininosuccinate synthase (EC 6.3.4.5) — —
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS33905 3-isopropylmalate dehydratase small subunit 0.13 BPHYT_RS15920 argininosuccinate synthase 0.74 8
Ralstonia solanacearum GMI1000 0.57 RS_RS09995 3-isopropylmalate dehydratase small subunit 0.77 RS_RS12800 argininosuccinate synthase — —
Paraburkholderia sabiae LMG 24235 0.57 QEN71_RS17615 3-isopropylmalate dehydratase small subunit 0.80 QEN71_RS09235 argininosuccinate synthase 0.82 16
Ralstonia sp. UNC404CL21Col 0.57 ABZR87_RS14535 3-isopropylmalate dehydratase small subunit 0.78 ABZR87_RS00835 argininosuccinate synthase 0.68 39
Ralstonia solanacearum UW163 0.57 UW163_RS11110 3-isopropylmalate dehydratase small subunit 0.77 UW163_RS08445 argininosuccinate synthase — —
Ralstonia solanacearum IBSBF1503 0.57 RALBFv3_RS02615 3-isopropylmalate dehydratase small subunit 0.77 RALBFv3_RS05180 argininosuccinate synthase — —
Paraburkholderia graminis OAS925 0.57 ABIE53_004803 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit 0.12 ABIE53_003355 argininosuccinate synthase — —
Variovorax sp. OAS795 0.56 ABID97_RS08460 3-isopropylmalate dehydratase small subunit 0.76 ABID97_RS21670 argininosuccinate synthase — —
Acidovorax sp. GW101-3H11 0.56 Ac3H11_1527 3-isopropylmalate dehydratase small subunit (EC 4.2.1.33) 0.78 Ac3H11_2616 Argininosuccinate synthase (EC 6.3.4.5) — —
Dechlorosoma suillum PS 0.55 Dsui_3199 3-isopropylmalate dehydratase, small subunit 0.13 Dsui_3248 argininosuccinate synthase — —
Acinetobacter radioresistens SK82 0.55 MPMX26_00346 3-isopropylmalate dehydratase small subunit 1 0.78 MPMX26_02260 Argininosuccinate synthase 0.87 35
Marinobacter adhaerens HP15 0.54 HP15_1833 isopropylmalate isomerase small subunit 0.11 HP15_2367 argininosuccinate synthase — —
Castellaniella sp019104865 MT123 0.53 ABCV34_RS04285 3-isopropylmalate dehydratase small subunit 0.79 ABCV34_RS05390 argininosuccinate synthase — —
Dinoroseobacter shibae DFL-12 0.49 Dshi_0083 3-isopropylmalate dehydratase, small subunit (RefSeq) 0.13 Dshi_3472 Argininosuccinate synthase (RefSeq) 0.63 25
Rhodopseudomonas palustris CGA009 0.49 TX73_001215 3-isopropylmalate dehydratase small subunit 0.79 TX73_002040 argininosuccinate synthase — —
Azospirillum sp. SherDot2 0.49 MPMX19_00606 3-isopropylmalate dehydratase small subunit 1 0.13 MPMX19_02369 Argininosuccinate synthase — —
Agrobacterium fabrum C58 0.48 Atu2790 3-isopropylmalate dehydratase, small subunit 0.14 Atu2667 argininosuccinate synthase — —
Sinorhizobium meliloti 1021 0.48 SMc03795 isopropylmalate isomerase small subunit 0.14 SMc03826 argininosuccinate synthase 0.73 73
Rhodospirillum rubrum S1H 0.48 Rru_A1190 3-isopropylmalate dehydratase small subunit region (NCBI) 0.15 Rru_A3751 Argininosuccinate synthase (NCBI) 0.75 12
Magnetospirillum magneticum AMB-1 0.47 AMB_RS20565 3-isopropylmalate dehydratase small subunit 0.13 AMB_RS05720 argininosuccinate synthase — —
Rhizobium sp. OAE497 0.47 ABIE40_RS19040 3-isopropylmalate dehydratase small subunit 0.14 ABIE40_RS18150 argininosuccinate synthase — —
Phaeobacter inhibens DSM 17395 0.47 PGA1_c29790 3-isopropylmalate dehydratase small subunit 0.14 PGA1_c34920 argininosuccinate synthase ArgG — —
Azospirillum brasilense Sp245 0.47 AZOBR_RS14135 isopropylmalate isomerase 0.14 AZOBR_RS00785 argininosuccinate synthase — —
Bosea sp. OAE506 0.45 ABIE41_RS11640 3-isopropylmalate dehydratase small subunit 0.12 ABIE41_RS00340 argininosuccinate synthase — —
Bifidobacterium breve UCC2003 0.41 BBR_RS19625 3-isopropylmalate dehydratase small subunit 0.11 BBR_RS13915 argininosuccinate synthase low > 34
Caulobacter crescentus NA1000 0.41 CCNA_00195 3-isopropylmalate dehydratase small subunit 0.13 CCNA_00128 argininosuccinate synthase — —
Caulobacter crescentus NA1000 Δfur 0.41 CCNA_00195 3-isopropylmalate dehydratase small subunit 0.13 CCNA_00128 argininosuccinate synthase low > 67
Sphingomonas koreensis DSMZ 15582 0.38 Ga0059261_4225 3-isopropylmalate dehydratase, small subunit 0.14 Ga0059261_1393 argininosuccinate synthase (EC 6.3.4.5) 0.97 6
Mycobacterium tuberculosis H37Rv 0.37 Rv2987c Probable 3-isopropylmalate dehydratase (small subunit) LeuD (isopropylmalate isomerase) (alpha-IPM isomerase) (IPMI) 0.13 Rv1658 Probable argininosuccinate synthase ArgG — —
Brevundimonas sp. GW460-12-10-14-LB2 0.37 A4249_RS10000 3-isopropylmalate dehydratase small subunit 0.12 A4249_RS14275 argininosuccinate synthase 0.99 18
Synechococcus elongatus PCC 7942 0.28 Synpcc7942_2548 leuD isopropylmalate isomerase small subunit 0.14 Synpcc7942_0009 argG argininosuccinate synthase — —

Not shown: 29 genomes with orthologs for OKFHMN_10730 only; 5 genomes with orthologs for OKFHMN_18090 only