| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Azospirillum sp. SherDot2 | 1.0 | MPMX19_01053 | | Dihydroorotase | 1.0 | MPMX19_00652 | | Sulfite reductase [ferredoxin] | 0.86 | 12 |
| Azospirillum brasilense Sp245 | 0.88 | AZOBR_RS20570 | | dihydroorotase | 0.84 | AZOBR_RS10125 | | sulfite reductase | — | — |
| Rhodospirillum rubrum S1H | 0.64 | Rru_A3191 | | Dihydroorotase multifunctional complex type (NCBI) | 0.57 | Rru_A1931 | | Ferredoxin--nitrite reductase (NCBI) | — | — |
| Rhodopseudomonas palustris CGA009 | 0.47 | TX73_016125 | | dihydroorotase | 0.61 | TX73_021840 | | nitrite/sulfite reductase | — | — |
| Bosea sp. OAE506 | 0.45 | ABIE41_RS17225 | | dihydroorotase | 0.62 | ABIE41_RS15335 | | nitrite/sulfite reductase | — | — |
| Xanthobacter sp. DMC5 | 0.45 | GFF930 | | Dihydroorotase | 0.60 | GFF2389 | | Sulfite reductase [ferredoxin] | — | — |
| Sinorhizobium meliloti 1021 | 0.43 | SMc01361 | | dihydroorotase | 0.60 | SMc02124 | | nitrite reductase | 0.68 | 64 |
| Caulobacter crescentus NA1000 Δfur | 0.42 | CCNA_02526 | | dihydroorotase | 0.59 | CCNA_01177 | | sulfite reductase, beta subunit | low | > 67 |
| Caulobacter crescentus NA1000 | 0.42 | CCNA_02526 | | dihydroorotase | 0.59 | CCNA_01177 | | sulfite reductase, beta subunit | low | > 66 |
| Rhizobium sp. OAE497 | 0.42 | ABIE40_RS07380 | | dihydroorotase | 0.63 | ABIE40_RS20885 | | DUF2849 domain-containing protein | — | — |
| Agrobacterium fabrum C58 | 0.42 | Atu1307 | | dihydroorotase | 0.61 | Atu1456 | | sulfite reductase (NADPH) hemoprotein beta-component | 0.77 | 43 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.40 | A4249_RS04255 | | dihydroorotase | 0.58 | A4249_RS09665 | | nitrite/sulfite reductase | — | — |
| Phaeobacter inhibens DSM 17395 | 0.40 | PGA1_c03020 | | dihydroorotase PyrC | 0.52 | PGA1_c20760 | | putative nitrite/sulfite reductase | — | — |
| Dinoroseobacter shibae DFL-12 | 0.38 | Dshi_3094 | | dihydroorotase, multifunctional complex type (RefSeq) | 0.55 | Dshi_1153 | | nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein (RefSeq) | — | — |
| Ralstonia sp. UNC404CL21Col | 0.38 | ABZR87_RS08630 | | dihydroorotase | 0.54 | ABZR87_RS00210 | | nitrite/sulfite reductase | low | > 80 |
| Ralstonia solanacearum GMI1000 | 0.37 | RS_RS03415 | | dihydroorotase | 0.54 | RS_RS12170 | | nitrite/sulfite reductase | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.37 | QEN71_RS25775 | | dihydroorotase | 0.56 | QEN71_RS25255 | | nitrite/sulfite reductase | low | > 153 |
| Ralstonia solanacearum IBSBF1503 | 0.37 | RALBFv3_RS12630 | | dihydroorotase | 0.55 | RALBFv3_RS04600 | | sulfite reductase | — | — |
| Ralstonia solanacearum UW163 | 0.37 | UW163_RS00935 | | dihydroorotase | 0.55 | UW163_RS09070 | | sulfite reductase | — | — |
| Ralstonia solanacearum PSI07 | 0.37 | RPSI07_RS20630 | | dihydroorotase | 0.55 | RPSI07_RS12775 | | nitrite/sulfite reductase | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.36 | H281DRAFT_04818 | | dihydroorotase | 0.55 | H281DRAFT_00114 | | sulfite reductase (NADPH) beta subunit | low | > 103 |
| Methylophilus sp. DMC18 | 0.36 | GFF867 | | Dihydroorotase-like protein | 0.56 | GFF1019 | | Sulfite reductase [ferredoxin] | — | — |
| Paraburkholderia graminis OAS925 | 0.36 | ABIE53_001133 | | dihydroorotase | 0.55 | ABIE53_001226 | | sulfite reductase (NADPH) hemoprotein beta-component | low | > 113 |
| Cupriavidus basilensis FW507-4G11 | 0.36 | RR42_RS15855 | | dihydroorotase | 0.56 | RR42_RS16270 | | sulfite reductase | — | — |
| Burkholderia phytofirmans PsJN | 0.35 | BPHYT_RS04245 | | dihydroorotase | 0.55 | BPHYT_RS04725 | | sulfite reductase | low | > 109 |
| Pseudomonas aeruginosa PA14 | 0.35 | IKLFDK_23415 | | dihydroorotase | 0.55 | IKLFDK_08940 | | sulfite reductase | low | > 100 |
| Pseudomonas sp. DMC3 | 0.34 | GFF205 | | Dihydroorotase-like protein | 0.54 | GFF3692 | | Sulfite reductase [ferredoxin] | — | — |
| Pseudomonas lactucae CFBP13502 | 0.34 | GEMAOFIL_05478 | | Dihydroorotase-like protein | 0.54 | GEMAOFIL_02703 | | Sulfite reductase [ferredoxin] | — | — |
| Pseudomonas fluorescens SBW25 | 0.34 | PFLU_RS28350 | | dihydroorotase | 0.54 | PFLU_RS12980 | | nitrite/sulfite reductase | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.34 | PFLU_RS28350 | | dihydroorotase | 0.54 | PFLU_RS12980 | | nitrite/sulfite reductase | — | — |
| Pseudomonas simiae WCS417 | 0.34 | PS417_26705 | | dihydroorotase | 0.54 | PS417_12290 | | sulfite reductase | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.33 | Pf1N1B4_2346 | | Dihydroorotase (EC 3.5.2.3) | 0.55 | Pf1N1B4_5665 | | Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) | — | — |
| Variovorax sp. OAS795 | 0.33 | ABID97_RS24655 | | dihydroorotase | 0.47 | ABID97_RS15380 | | nitrite/sulfite reductase | low | > 91 |
| Pseudomonas segetis P6 | 0.33 | MPMX49_00619 | | Dihydroorotase-like protein | 0.54 | MPMX49_02597 | | Sulfite reductase [ferredoxin] | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.33 | PfGW456L13_1015 | | Dihydroorotase (EC 3.5.2.3) | 0.55 | PfGW456L13_2843 | | Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) | — | — |
| Acidovorax sp. GW101-3H11 | 0.33 | Ac3H11_3977 | | Dihydroorotase (EC 3.5.2.3) | 0.45 | Ac3H11_577 | | Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) | — | — |
| Pseudomonas sp. SVBP6 | 0.33 | COO64_RS13570 | | dihydroorotase | 0.55 | COO64_RS24895 | | nitrite/sulfite reductase | low | > 93 |
| Pseudomonas stutzeri RCH2 | 0.33 | Psest_0290 | | dihydroorotase, multifunctional complex type | 0.53 | Psest_2089 | | Sulfite reductase, beta subunit (hemoprotein) | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.33 | Psyr_0481 | | dihydroorotase | 0.56 | Psyr_2462 | | Nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like:Nitrite and sulphite reductase 4Fe-4S region | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.33 | Psyr_0481 | | dihydroorotase | 0.56 | Psyr_2462 | | Nitrite/sulfite reductase, hemoprotein beta-component, ferrodoxin-like:Nitrite and sulphite reductase 4Fe-4S region | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.33 | AO356_13445 | | dihydroorotase | 0.55 | AO356_00555 | | sulfite reductase | low | > 104 |
| Pseudomonas fluorescens FW300-N2E3 | 0.33 | AO353_08140 | | dihydroorotase | 0.54 | AO353_22800 | | sulfite reductase | — | — |
| Sphingomonas koreensis DSMZ 15582 | 0.33 | Ga0059261_0075 | | Dihydroorotase and related cyclic amidohydrolases | 0.61 | Ga0059261_1498 | | Sulfite reductase, beta subunit (hemoprotein) | — | — |
| Pseudomonas putida KT2440 | 0.33 | PP_4999 | | dihydroorotase-like protein | 0.55 | PP_2371 | | Sulphite reductase hemoprotein, beta subunit | 0.38 | 21 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.33 | GFF652 | | Dihydroorotase (EC 3.5.2.3) | 0.46 | GFF4293 | | Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) | low | > 90 |
| Pseudomonas fluorescens FW300-N2E2 | 0.32 | Pf6N2E2_4605 | | Dihydroorotase (EC 3.5.2.3) | 0.55 | Pf6N2E2_2073 | | Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) | — | — |
| Pseudomonas sp. S08-1 | 0.32 | OH686_10945 | | Dihydroorotase | 0.55 | OH686_03470 | | Sulfite reductase [NADPH] hemoprotein beta-component | — | — |
| Herbaspirillum seropedicae SmR1 | 0.32 | HSERO_RS02340 | | dihydroorotase | 0.58 | HSERO_RS15550 | | sulfite reductase | 0.53 | 31 |
| Sphingobium sp. HT1-2 | 0.32 | GFF1873 | | Dihydroorotase (EC 3.5.2.3) | 0.60 | GFF1452 | | Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) | — | — |
| Pseudomonas sp. RS175 | 0.32 | PFR28_04238 | | Dihydroorotase-like protein | 0.55 | PFR28_01366 | | Sulfite reductase [ferredoxin] | — | — |
| Pseudomonas sp. BP01 | 0.32 | JOY50_RS09695 | | dihydroorotase | 0.59 | JOY50_RS02185 | | DUF2849 domain-containing protein | low | > 84 |
| Variovorax sp. SCN45 | 0.32 | GFF2161 | | Dihydroorotase (EC 3.5.2.3) | 0.45 | GFF1206 | | Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) | low | > 127 |
| Mycobacterium tuberculosis H37Rv | 0.30 | Rv1381 | | Probable dihydroorotase PyrC (DHOase) | 0.16 | Rv2391 | | Ferredoxin-dependent sulfite reductase SirA | — | — |
| Dechlorosoma suillum PS | 0.29 | Dsui_0597 | | dihydroorotase, multifunctional complex type | 0.55 | Dsui_1986 | | sulfite reductase, beta subunit (hemoprotein) | — | — |
| Marinobacter adhaerens HP15 | 0.28 | HP15_3506 | | dihydroorotase, multifunctional complex type | 0.53 | HP15_1795 | | sulfite reductase hemoprotein, beta subunit | 0.57 | 65 |
| Acinetobacter baumannii LAC-4 | 0.24 | RR41_RS10090 | | dihydroorotase | 0.54 | RR41_RS03245 | | nitrite/sulfite reductase | — | — |
| Synechocystis sp000284455 PCC 6803 | 0.24 | SGL_RS03805 | | dihydroorotase | 0.14 | SGL_RS14775 | | ferredoxin--nitrite reductase | — | — |
| Acinetobacter radioresistens SK82 | 0.22 | MPMX26_01100 | | Dihydroorotase-like protein | 0.54 | MPMX26_00614 | | Sulfite reductase [ferredoxin] | 0.87 | 13 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.17 | Xcc-8004.2303.1 | | Dihydroorotase (EC 3.5.2.3) | 0.09 | Xcc-8004.1257.1 | | Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2) | — | — |
Not shown: 15 genomes with orthologs for MPMX19_01053 only; 39 genomes with orthologs for MPMX19_00652 only