Conservation of cofitness between GFF879 and GFF765 in Sphingobium sp. HT1-2

80 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sphingobium sp. HT1-2 1.0 GFF879 CobW GTPase involved in cobalt insertion for B12 biosynthesis 1.0 GFF765 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) 0.89 4
Rhizobium sp. OAE497 0.59 ABIE40_RS11160 cobalamin biosynthesis protein CobW 0.40 ABIE40_RS16275 glutamate synthase large subunit — —
Sinorhizobium meliloti 1021 0.58 SMc04304 cobalamine biosynthesis protein 0.39 SMc04028 glutamate synthase — —
Rhodospirillum rubrum S1H 0.57 Rru_A0671 cobalamin synthesis CobW protein (NCBI) 0.64 Rru_A0019 Glutamate synthase (ferredoxin) (NCBI) — —
Magnetospirillum magneticum AMB-1 0.57 AMB_RS22390 cobalamin biosynthesis protein CobW 0.63 AMB_RS02685 glutamate synthase large subunit — —
Azospirillum sp. SherDot2 0.55 MPMX19_05574 hypothetical protein 0.64 MPMX19_02657 Glutamate synthase [NADPH] large chain — —
Agrobacterium fabrum C58 0.54 Atu2805 cobalamin synthesis protein 0.40 Atu3784 glutamate synthase large subunit 0.23 67
Bosea sp. OAE506 0.54 ABIE41_RS01785 cobalamin biosynthesis protein CobW 0.40 ABIE41_RS08565 glutamate synthase large subunit — —
Dinoroseobacter shibae DFL-12 0.54 Dshi_0160 cobalamin biosynthesis protein CobW (RefSeq) 0.61 Dshi_0002 Glutamate synthase (ferredoxin) (RefSeq) low > 64
Xanthobacter sp. DMC5 0.54 GFF3291 P-loop guanosine triphosphatase YjiA 0.40 GFF2524 Ferredoxin-dependent glutamate synthase 1 — —
Phaeobacter inhibens DSM 17395 0.52 PGA1_c08180 cobalamin biosynthesis protein CobW 0.61 PGA1_c36100 glutamate synthase [NADPH] large chain — —
Paraburkholderia bryophila 376MFSha3.1 0.51 H281DRAFT_06525 cobalamin biosynthesis protein CobW 0.40 H281DRAFT_05620 glutamate synthase (NADH) large subunit low > 103
Synechococcus elongatus PCC 7942 0.51 Synpcc7942_0827 cobW cobalamin synthesis protein cobW-like 0.40 Synpcc7942_0890 glsF glutamate synthase (ferredoxin) — —
Pseudomonas sp. SVBP6 0.50 COO64_RS14640 cobW cobalamin biosynthesis protein CobW 0.39 COO64_RS13085 gltB glutamate synthase large subunit low > 93
Pseudomonas aeruginosa PUPa3 0.50 DQ20_RS33330 cobW;go_process=cobalamin cobalamin biosynthesis protein CobW 0.39 DQ20_RS51075 gltB;go_function=catalytic glutamate synthase large subunit low > 101
Pseudomonas aeruginosa MRSN321 0.50 DY961_RS02255 cobW;go_process=cobalamin cobalamin biosynthesis protein CobW 0.39 DY961_RS11000 gltB;go_function=catalytic glutamate synthase large subunit low > 100
Rhodopseudomonas palustris CGA009 0.50 TX73_003700 cobalamin biosynthesis protein CobW 0.40 TX73_004590 glutamate synthase large subunit — —
Pseudomonas aeruginosa PA14 0.50 IKLFDK_14975 cobalamin biosynthesis protein CobW 0.39 IKLFDK_28355 glutamate synthase large subunit low > 98
Pseudomonas orientalis W4I3 0.49 QF045_RS14880 cobalamin biosynthesis protein CobW 0.40 QF045_RS05060 glutamate synthase large subunit low > 93
Hydrogenophaga sp. GW460-11-11-14-LB1 0.49 GFF3985 CobW GTPase involved in cobalt insertion for B12 biosynthesis 0.39 GFF1327 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) — —
Pseudomonas fluorescens FW300-N2E2 0.49 Pf6N2E2_2061 CobW GTPase involved in cobalt insertion for B12 biosynthesis 0.40 Pf6N2E2_3752 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) low > 103
Pseudomonas sp. DMC3 0.49 GFF3680 hypothetical protein 0.39 GFF3102 Glutamate synthase [NADPH] large chain low > 89
Pseudomonas sp. BP01 0.49 JOY50_RS06025 cobW cobalamin biosynthesis protein CobW 0.40 JOY50_RS09320 gltB glutamate synthase large subunit 0.83 68
Pseudomonas sp. RS175 0.49 PFR28_01376 hypothetical protein 0.39 PFR28_05015 Glutamate synthase [NADPH] large chain low > 88
Pseudomonas putida KT2440 0.49 PP_3508 Protein CobW 0.39 PP_5076 L-glutamate synthase(NADPH) alpha subunit low > 96
Burkholderia phytofirmans PsJN 0.49 BPHYT_RS24840 cobalamin biosynthesis protein CobW 0.40 BPHYT_RS17855 glutamate synthase 0.38 88
Pseudomonas fluorescens FW300-N1B4 0.49 Pf1N1B4_5654 CobW GTPase involved in cobalt insertion for B12 biosynthesis 0.39 Pf1N1B4_1534 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) — —
Pseudomonas syringae pv. syringae B728a 0.49 Psyr_3016 Cobalamin synthesis protein/P47K:Cobalamin synthesis protein/P47K 0.39 Psyr_0411 glutamate synthase (NADPH) large subunit — —
Pseudomonas fluorescens FW300-N2C3 0.49 AO356_00510 cobalamin biosynthesis protein CobW 0.40 AO356_09375 glutamate synthase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.49 Psyr_3016 Cobalamin synthesis protein/P47K:Cobalamin synthesis protein/P47K 0.39 Psyr_0411 glutamate synthase (NADPH) large subunit — —
Synechocystis sp000284455 PCC 6803 0.49 SGL_RS15425 cobalamin biosynthesis protein CobW 0.40 SGL_RS17380 glutamate synthase large subunit low > 52
Pseudomonas sp. S08-1 0.49 OH686_05060 cobalamin biosynthesis protein CobW 0.40 OH686_10005 Glutamate synthase [NADPH] large chain low > 80
Pseudomonas fluorescens GW456-L13 0.49 PfGW456L13_2854 CobW GTPase involved in cobalt insertion for B12 biosynthesis 0.40 PfGW456L13_272 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) 0.39 24
Pseudomonas lactucae CFBP13502 0.48 GEMAOFIL_02718 hypothetical protein 0.39 GEMAOFIL_00632 Glutamate synthase [NADPH] large chain low > 96
Pseudomonas fluorescens SBW25-INTG 0.48 PFLU_RS13035 cobalamin biosynthesis protein CobW 0.39 PFLU_RS02045 glutamate synthase large subunit low > 109
Pseudomonas fluorescens SBW25 0.48 PFLU_RS13035 cobalamin biosynthesis protein CobW 0.39 PFLU_RS02045 glutamate synthase large subunit low > 109
Pseudomonas fluorescens FW300-N2E3 0.48 AO353_21655 cobalamin biosynthesis protein CobW 0.39 AO353_12515 glutamate synthase low > 101
Paraburkholderia sabiae LMG 24235 0.48 QEN71_RS08710 cobalamin biosynthesis protein CobW 0.40 QEN71_RS28010 glutamate synthase-related protein low > 153
Pseudomonas simiae WCS417 0.47 PS417_12345 cobalamin biosynthesis protein CobW 0.40 PS417_02000 glutamate synthase low > 88
Variovorax sp. SCN45 0.46 GFF828 CobW GTPase involved in cobalt insertion for B12 biosynthesis 0.39 GFF5332 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) low > 127
Cupriavidus basilensis FW507-4G11 0.44 RR42_RS32335 cobalamin biosynthesis protein CobW 0.40 RR42_RS18990 glutamate synthase low > 128
Brevundimonas sp. GW460-12-10-14-LB2 0.25 A4249_RS14930 GTP-binding protein 0.51 A4249_RS16105 glutamate synthase large subunit — —
Dechlorosoma suillum PS 0.25 Dsui_0589 putative GTPase, G3E family 0.39 Dsui_1096 glutamate synthase family protein low > 51
Ralstonia solanacearum PSI07 0.23 RPSI07_RS02205 GTP-binding protein 0.39 RPSI07_RS10320 glutamate synthase subunit alpha low > 81
Ralstonia solanacearum GMI1000 0.23 RS_RS20070 GTP-binding protein 0.39 RS_RS14860 glutamate synthase subunit alpha low > 80
Ralstonia solanacearum IBSBF1503 0.23 RALBFv3_RS20535 GTP-binding protein 0.39 RALBFv3_RS06915 glutamate synthase subunit alpha low > 76
Ralstonia solanacearum UW163 0.23 UW163_RS18640 GTP-binding protein 0.39 UW163_RS06700 glutamate synthase subunit alpha — —
Methylophilus sp. DMC18 0.21 GFF602 P-loop guanosine triphosphatase YjiA 0.40 GFF2799 Ferredoxin-dependent glutamate synthase 1 — —
Caulobacter crescentus NA1000 Δfur 0.21 CCNA_00323 low-affinity zinc transport protein 0.60 CCNA_03722 glutamate synthase (NADPH) large chain GltB low > 67
Caulobacter crescentus NA1000 0.21 CCNA_00323 low-affinity zinc transport protein 0.60 CCNA_03722 glutamate synthase (NADPH) large chain GltB low > 66
Pseudomonas segetis P6 0.21 MPMX49_02070 Putative metal chaperone YciC 0.39 MPMX49_04231 Glutamate synthase [NADPH] large chain low > 75
Ralstonia sp. UNC404CL21Col 0.21 ABZR87_RS17410 GTP-binding protein 0.39 ABZR87_RS02570 glutamate synthase-related protein low > 80
Herbaspirillum seropedicae SmR1 0.20 HSERO_RS04655 hypothetical protein 0.40 HSERO_RS19595 glutamate synthase low > 78
Echinicola vietnamensis KMM 6221, DSM 17526 0.20 Echvi_3326 Putative GTPases (G3E family) 0.39 Echvi_1244 Glutamate synthase domain 2 low > 79
Castellaniella sp019104865 MT123 0.19 ABCV34_RS13425 GTP-binding protein 0.40 ABCV34_RS11150 glutamate synthase-related protein low > 48
Escherichia coli ECRC100 0.19 OKFHMN_11395 yjiA GTPase 0.38 OKFHMN_17885 gltB glutamate synthase large subunit low > 79
Escherichia coli BL21 0.19 ECD_04218 metal-binding GTPase 0.38 ECD_03077 glutamate synthase, large subunit low > 61
Escherichia coli ECRC101 0.19 MCAODC_01910 yjiA GTPase 0.38 MCAODC_08405 gltB glutamate synthase large subunit low > 87
Escherichia coli ECRC99 0.19 KEDOAH_16750 yjiA GTPase 0.38 KEDOAH_10265 gltB glutamate synthase large subunit — —
Escherichia coli Nissle 1917 0.19 ECOLIN_RS24980 GTPase 0.38 ECOLIN_RS18475 glutamate synthase large subunit low > 55
Escherichia coli ECRC62 0.19 BNILDI_07825 yjiA GTPase 0.38 BNILDI_01850 gltB glutamate synthase large subunit low > 75
Klebsiella michiganensis M5al 0.19 BWI76_RS03810 GTPase 0.39 BWI76_RS25315 glutamate synthase large subunit low > 92
Escherichia coli ECRC98 0.19 JDDGAC_14990 yjiA GTPase 0.38 JDDGAC_21510 gltB glutamate synthase large subunit low > 87
Escherichia coli ECRC102 0.19 NIAGMN_09245 yjiA GTPase 0.38 NIAGMN_15645 gltB glutamate synthase large subunit low > 80
Escherichia coli HS(pFamp)R (ATCC 700891) 0.19 OHPLBJKB_03722 putative GTP-binding protein YjiA 0.38 OHPLBJKB_00488 Glutamate synthase [NADPH] large chain low > 74
Escherichia coli ECOR27 0.19 NOLOHH_03775 yjiA GTPase 0.38 NOLOHH_09685 gltB glutamate synthase large subunit low > 76
Escherichia coli BW25113 0.19 b4352 yjiA orf, hypothetical protein (VIMSS) 0.38 b3212 gltB glutamate synthase, large subunit (NCBI) low > 76
Escherichia coli ECOR38 0.19 HEPCGN_09435 yjiA GTPase 0.38 HEPCGN_16760 gltB3 Glutamate synthase domain 3 low > 88
Enterobacter asburiae PDN3 0.19 EX28DRAFT_3534 Putative GTPases (G3E family) 0.39 EX28DRAFT_3275 Glutamate synthase domain 2 low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.19 GFF1006 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family 0.38 GFF2956 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) low > 78
Escherichia fergusonii Becca 0.19 EFB2_04096 P-loop guanosine triphosphatase YjiA 0.38 EFB2_00611 Glutamate synthase [NADPH] large chain low > 86
Variovorax sp. OAS795 0.19 ABID97_RS06160 GTP-binding protein 0.40 ABID97_RS23225 glutamate synthase-related protein low > 91
Klebsiella pneumoniae MKP103 0.19 KDGMDA_12050 GTPase 0.40 KDGMDA_06145 glutamate synthase large subunit low > 95
Enterobacter sp. TBS_079 0.18 MPMX20_00629 P-loop guanosine triphosphatase YjiA 0.39 MPMX20_04126 Glutamate synthase [NADPH] large chain low > 85
Serratia liquefaciens MT49 0.18 IAI46_02540 GTPase 0.39 IAI46_22345 glutamate synthase large subunit low > 87
Rahnella sp. WP5 0.18 EX31_RS00785 GTPase 0.40 EX31_RS12515 glutamate synthase large subunit low > 89
Dickeya dadantii 3937 0.17 DDA3937_RS16350 GTPase 0.40 DDA3937_RS01665 glutamate synthase large subunit low > 74
Dickeya dianthicola ME23 0.17 DZA65_RS17535 GTPase 0.40 DZA65_RS01635 glutamate synthase large subunit low > 75
Dickeya dianthicola 67-19 0.17 HGI48_RS16450 GTPase 0.40 HGI48_RS01560 glutamate synthase large subunit low > 71
Acidovorax sp. GW101-3H11 0.17 Ac3H11_2001 Putative metal chaperone, involved in Zn homeostasis, GTPase of COG0523 family 0.39 Ac3H11_4710 Glutamate synthase [NADPH] large chain (EC 1.4.1.13) low > 79
Vibrio cholerae E7946 ATCC 55056 0.13 CSW01_16870 GTP-binding protein 0.39 CSW01_12020 glutamate synthase large subunit low > 62

Not shown: 2 genomes with orthologs for GFF879 only; 30 genomes with orthologs for GFF765 only