| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Sphingobium sp. HT1-2 | 1.0 | GFF3399 | | Lactate-responsive regulator LldR in Enterobacteria, GntR family | 1.0 | GFF3820 | | RNase adapter protein RapZ | 0.71 | 13 |
| Castellaniella sp019104865 MT123 | 0.37 | ABCV34_RS10290 | | transcriptional regulator LldR | 0.29 | ABCV34_RS14330 | | RNase adapter RapZ | low | > 48 |
| Enterobacter sp. TBS_079 | 0.36 | MPMX20_00130 | | Putative L-lactate dehydrogenase operon regulatory protein | 0.29 | MPMX20_04111 | | RNase adapter protein RapZ | low | > 85 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.36 | GFF410 | | Lactate-responsive regulator LldR in Enterobacteria, GntR family | 0.29 | GFF2949 | | Hypothetical ATP-binding protein UPF0042, contains P-loop | low | > 78 |
| Enterobacter asburiae PDN3 | 0.36 | EX28DRAFT_3854 | | Transcriptional regulators | 0.29 | EX28DRAFT_3259 | | Predicted P-loop-containing kinase | low | > 76 |
| Escherichia coli ECRC62 | 0.36 | BNILDI_03860 | lldR | transcriptional regulator LldR | 0.29 | BNILDI_01810 | rapZ | RNase adapter RapZ | low | > 75 |
| Escherichia coli ECOR27 | 0.36 | NOLOHH_07655 | lldR | transcriptional regulator LldR | 0.29 | NOLOHH_09725 | rapZ | RNase adapter RapZ | low | > 76 |
| Klebsiella pneumoniae MKP103 | 0.36 | KDGMDA_07875 | | transcriptional regulator LldR | 0.29 | KDGMDA_06095 | | RNase adapter RapZ | low | > 95 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.35 | OHPLBJKB_00095 | | Putative L-lactate dehydrogenase operon regulatory protein | 0.29 | OHPLBJKB_00495 | | RNase adapter protein RapZ | low | > 74 |
| Escherichia coli BW25113 | 0.35 | b3604 | lldR | DNA-binding transcriptional repressor (NCBI) | 0.29 | b3205 | yhbJ | hypothetical protein (NCBI) | low | > 76 |
| Escherichia coli BL21 | 0.35 | ECD_03462 | | dual role activator/repressor for lldPRD operon | 0.29 | ECD_03070 | | adaptor protein for GlmZ/GlmY sRNA decay, glucosamine-6-phosphate-regulated; NTPase | low | > 61 |
| Pantoea sp. MT58 | 0.35 | IAI47_15025 | | transcriptional regulator LldR | 0.29 | IAI47_17200 | | RNase adapter RapZ | low | > 76 |
| Klebsiella michiganensis M5al | 0.35 | BWI76_RS27190 | | transcriptional regulator LldR | 0.30 | BWI76_RS25280 | | RNase adaptor protein RapZ | low | > 92 |
| Escherichia coli ECRC99 | 0.35 | KEDOAH_12375 | lldR | transcriptional regulator LldR | 0.29 | KEDOAH_10225 | rapZ | RNase adapter RapZ | — | — |
| Escherichia coli ECRC100 | 0.35 | OKFHMN_15775 | lldR | transcriptional regulator LldR | 0.29 | OKFHMN_17925 | rapZ | RNase adapter RapZ | low | > 79 |
| Escherichia coli ECRC102 | 0.35 | NIAGMN_13535 | lldR | transcriptional regulator LldR | 0.29 | NIAGMN_15685 | rapZ | RNase adapter RapZ | low | > 80 |
| Escherichia coli ECRC101 | 0.35 | MCAODC_06285 | lldR | transcriptional regulator LldR | 0.29 | MCAODC_08445 | rapZ | RNase adapter RapZ | low | > 87 |
| Escherichia coli ECRC98 | 0.35 | JDDGAC_19400 | lldR | transcriptional regulator LldR | 0.29 | JDDGAC_21550 | rapZ | RNase adapter RapZ | low | > 87 |
| Escherichia coli Nissle 1917 | 0.35 | ECOLIN_RS20575 | | transcriptional regulator LldR | 0.29 | ECOLIN_RS18440 | | RNase adapter RapZ | low | > 55 |
| Escherichia coli ECOR38 | 0.35 | HEPCGN_14615 | lldR | transcriptional regulator LldR | 0.29 | HEPCGN_16800 | rapZ | RNase adapter RapZ | low | > 88 |
| Escherichia fergusonii Becca | 0.35 | EFB2_00206 | | Putative L-lactate dehydrogenase operon regulatory protein | 0.29 | EFB2_00618 | | RNase adapter protein RapZ | 0.47 | 44 |
| Pantoea agglomerans CFBP13505 P0401 | 0.34 | PagCFBP13505_RS10135 | | transcriptional regulator LldR | 0.29 | PagCFBP13505_RS09365 | | RNase adapter RapZ | low | > 74 |
| Acinetobacter baumannii LAC-4 | 0.32 | RR41_RS18510 | | transcriptional regulator LldR | 0.28 | RR41_RS16040 | | RNase adapter RapZ | low | > 55 |
| Acinetobacter radioresistens SK82 | 0.30 | MPMX26_02258 | | Putative L-lactate dehydrogenase operon regulatory protein | 0.27 | MPMX26_00547 | | RNase adapter protein RapZ | low | > 36 |
| Pseudomonas sp. S08-1 | 0.28 | OH686_17020 | | Lactate-responsive regulator LldR in Enterobacteria, GntR family | 0.29 | OH686_08560 | | RNase adapter protein RapZ | low | > 80 |
| Pseudomonas aeruginosa PUPa3 | 0.28 | DQ20_RS52435 | | FCD domain-containing protein | 0.29 | DQ20_RS56610 | rapZ;go_function=ATP | RNase adapter RapZ | low | > 101 |
| Pseudomonas aeruginosa MRSN321 | 0.28 | DY961_RS09605 | | FCD domain-containing protein | 0.29 | DY961_RS24150 | rapZ;go_function=ATP | RNase adapter RapZ | low | > 100 |
| Pseudomonas segetis P6 | 0.28 | MPMX49_01174 | | Pyruvate dehydrogenase complex repressor | 0.28 | MPMX49_03861 | | RNase adapter protein RapZ | low | > 75 |
| Pseudomonas aeruginosa PA14 | 0.28 | IKLFDK_29745 | | transcriptional regulator PdhR | 0.29 | IKLFDK_01755 | | RNase adapter RapZ | low | > 98 |
| Pseudomonas fluorescens FW300-N2E2 | 0.27 | Pf6N2E2_3379 | | Lactate-responsive regulator LldR in Enterobacteria, GntR family | 0.29 | Pf6N2E2_3270 | | Hypothetical ATP-binding protein UPF0042, contains P-loop | low | > 103 |
| Magnetospirillum magneticum AMB-1 | 0.27 | AMB_RS01210 | | FCD domain-containing protein | 0.40 | AMB_RS22235 | | RNase adaptor protein RapZ | — | — |
| Pseudomonas sp. SVBP6 | 0.27 | COO64_RS15305 | | GntR family transcriptional regulator | 0.29 | COO64_RS04270 | rapZ | RNase adapter RapZ | low | > 93 |
| Pseudomonas fluorescens SBW25 | 0.27 | PFLU_RS25940 | | FCD domain-containing protein | 0.30 | PFLU_RS04385 | | RNase adapter RapZ | low | > 109 |
| Pseudomonas lactucae CFBP13502 | 0.27 | GEMAOFIL_04970 | | Pyruvate dehydrogenase complex repressor | 0.29 | GEMAOFIL_01072 | | RNase adapter protein RapZ | low | > 96 |
| Pseudomonas fluorescens SBW25-INTG | 0.27 | PFLU_RS25940 | | FCD domain-containing protein | 0.30 | PFLU_RS04385 | | RNase adapter RapZ | low | > 109 |
| Pseudomonas fluorescens GW456-L13 | 0.26 | PfGW456L13_5113 | | Lactate-responsive regulator LldR in Enterobacteria, GntR family | 0.29 | PfGW456L13_5017 | | Hypothetical ATP-binding protein UPF0042, contains P-loop | low | > 87 |
| Pseudomonas fluorescens FW300-N2E3 | 0.26 | AO353_05695 | | transcriptional regulator PdhR | 0.29 | AO353_05195 | | glmZ(sRNA)-inactivating NTPase | 0.27 | 28 |
| Pseudomonas orientalis W4I3 | 0.26 | QF045_RS26355 | | FCD domain-containing protein | 0.29 | QF045_RS07320 | | RNase adapter RapZ | low | > 93 |
| Pseudomonas fluorescens FW300-N2C3 | 0.26 | AO356_07545 | | transcriptional regulator PdhR | 0.29 | AO356_07050 | | glmZ(sRNA)-inactivating NTPase | low | > 104 |
| Pseudomonas fluorescens FW300-N1B4 | 0.26 | Pf1N1B4_1185 | | Lactate-responsive regulator LldR in Enterobacteria, GntR family | 0.29 | Pf1N1B4_1083 | | Hypothetical ATP-binding protein UPF0042, contains P-loop | — | — |
| Pseudomonas sp. BP01 | 0.26 | JOY50_RS26710 | | FCD domain-containing protein | 0.29 | JOY50_RS11115 | rapZ | RNase adapter RapZ | low | > 84 |
| Pseudomonas sp. DMC3 | 0.26 | GFF4964 | | Pyruvate dehydrogenase complex repressor | 0.29 | GFF1825 | | RNase adapter protein RapZ | 0.86 | 3 |
| Pseudomonas sp. RS175 | 0.25 | PFR28_00064 | | Pyruvate dehydrogenase complex repressor | 0.29 | PFR28_00170 | | RNase adapter protein RapZ | low | > 88 |
| Pseudomonas putida KT2440 | 0.25 | PP_4734 | | DNA-binding transcriptional dual regulator, LldR-L-lactate | 0.29 | PP_0949 | | putative ATP-binding protein UPF0042 | low | > 96 |
| Pseudomonas simiae WCS417 | 0.25 | PS417_24100 | | transcriptional regulator PdhR | 0.30 | PS417_04330 | | glmZ(sRNA)-inactivating NTPase | — | — |
| Pseudomonas stutzeri RCH2 | 0.25 | Psest_0956 | | Transcriptional regulators | 0.27 | Psest_3316 | | Predicted P-loop-containing kinase | low | > 67 |
| Burkholderia phytofirmans PsJN | 0.23 | BPHYT_RS26990 | | GntR family transcriptional regulator | 0.30 | BPHYT_RS02885 | | glmZ(sRNA)-inactivating NTPase | low | > 109 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.23 | H281DRAFT_02906 | | transcriptional regulator, GntR family | 0.30 | H281DRAFT_01931 | | UPF0042 nucleotide-binding protein | low | > 103 |
| Paraburkholderia graminis OAS925 | 0.23 | ABIE53_005884 | | GntR family transcriptional repressor for pyruvate dehydrogenase complex | 0.30 | ABIE53_000714 | | UPF0042 nucleotide-binding protein | low | > 113 |
| Alteromonas macleodii MIT1002 | 0.23 | MIT1002_03004 | | Pyruvate dehydrogenase complex repressor | 0.29 | MIT1002_00824 | | glmZ(sRNA)-inactivating NTPase | low | > 70 |
| Pectobacterium carotovorum WPP14 | 0.22 | HER17_RS03285 | | pyruvate dehydrogenase complex transcriptional repressor PdhR | 0.29 | HER17_RS20075 | | RNase adapter RapZ | low | > 75 |
| Azospirillum sp. SherDot2 | 0.22 | MPMX19_06090 | | Pyruvate dehydrogenase complex repressor | 0.40 | MPMX19_02622 | | Nucleotide-binding protein | low | > 112 |
| Dickeya dianthicola 67-19 | 0.22 | HGI48_RS17855 | | pyruvate dehydrogenase complex transcriptional repressor PdhR | 0.30 | HGI48_RS01430 | | RNase adapter RapZ | 0.32 | 67 |
| Erwinia tracheiphila SCR3 | 0.22 | LU632_RS03075 | pdhR | pyruvate dehydrogenase complex transcriptional repressor PdhR | 0.29 | LU632_RS21295 | rapZ | RNase adapter RapZ | low | > 73 |
| Serratia liquefaciens MT49 | 0.22 | IAI46_21330 | | pyruvate dehydrogenase complex transcriptional repressor PdhR | 0.30 | IAI46_22485 | | RNase adapter RapZ | 0.45 | 67 |
| Dickeya dianthicola ME23 | 0.22 | DZA65_RS19005 | | pyruvate dehydrogenase complex transcriptional repressor PdhR | 0.30 | DZA65_RS01495 | | RNase adapter RapZ | low | > 75 |
| Dickeya dadantii 3937 | 0.22 | DDA3937_RS17930 | | pyruvate dehydrogenase complex transcriptional repressor PdhR | 0.30 | DDA3937_RS01515 | | RNase adapter RapZ | low | > 74 |
| Paraburkholderia sabiae LMG 24235 | 0.21 | QEN71_RS10135 | | FadR/GntR family transcriptional regulator | 0.31 | QEN71_RS01735 | | RNase adapter RapZ | low | > 153 |
| Erwinia tracheiphila HP pepo 2.2 | 0.21 | IJEDHG_05795 | | Pyruvate dehydrogenase complex repressor | 0.29 | IJEDHG_13725 | rapZ | RNase adapter RapZ | 0.63 | 51 |
| Rahnella sp. WP5 | 0.21 | EX31_RS03485 | | pyruvate dehydrogenase complex transcriptional repressor PdhR | 0.30 | EX31_RS12385 | | RNase adapter RapZ | low | > 89 |
| Shewanella oneidensis MR-1 | 0.21 | SO0423 | pdhR | pyruvate dehydrogenase complex repressor (NCBI ptt file) | 0.31 | SO3964 | | conserved hypothetical protein (NCBI ptt file) | low | > 76 |
| Shewanella sp. ANA-3 | 0.21 | Shewana3_0425 | pdhR | transcriptional regulator PdhR (RefSeq) | 0.31 | Shewana3_0669 | | hypothetical protein (RefSeq) | low | > 73 |
| Vibrio cholerae E7946 ATCC 55056 | 0.21 | CSW01_12225 | | pyruvate dehydrogenase complex transcriptional repressor PdhR | 0.31 | CSW01_12830 | | RNase adaptor protein RapZ | low | > 62 |
| Erwinia amylovora T8 | 0.20 | OLJFJH_01000 | | pyruvate dehydrogenase complex transcriptional repressor PdhR | 0.30 | OLJFJH_07055 | | RNase adapter RapZ | low | > 58 |
| Dinoroseobacter shibae DFL-12 | 0.20 | Dshi_3026 | | GntR domain protein (RefSeq) | 0.39 | Dshi_0209 | | hypothetical protein (RefSeq) | low | > 64 |
| Shewanella loihica PV-4 | 0.19 | Shew_3432 | pdhR | transcriptional regulator PdhR (RefSeq) | 0.29 | Shew_3314 | | hypothetical protein (RefSeq) | — | — |
| Shewanella amazonensis SB2B | 0.19 | Sama_0374 | pdhR | transcriptional regulator PdhR (RefSeq) | 0.29 | Sama_3091 | | hypothetical protein (RefSeq) | low | > 62 |
| Azospirillum brasilense Sp245 | 0.19 | AZOBR_RS25130 | | GntR family transcriptional regulator | 0.41 | AZOBR_RS30485 | | nucleotide-binding protein | low | > 97 |
| Phaeobacter inhibens DSM 17395 | 0.17 | PGA1_c00760 | | putative pyruvate dehydrogenase complex repressor | 0.37 | PGA1_c01180 | | Predicted P-loop-containing kinase | low | > 62 |
| Rhodospirillum rubrum S1H | 0.15 | Rru_A1414 | | regulatory protein GntR (NCBI) | 0.41 | Rru_A3448 | | Uncharacterized P-loop ATPase protein UPF0042 (NCBI) | low | > 58 |
| Cupriavidus basilensis FW507-4G11 | 0.15 | RR42_RS21300 | | GntR family transcriptional regulator | 0.25 | RR42_RS02060 | | nucleotide-binding protein | low | > 128 |
| Desulfovibrio vulgaris Miyazaki F | 0.15 | DvMF_1205 | | GntR domain protein (RefSeq) | 0.28 | DvMF_0424 | | hypothetical protein (RefSeq) | low | > 51 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.14 | Psyr_0299 | | transcriptional regulator, GntR family | 0.29 | Psyr_4150 | | Uncharacterized P-loop ATPase protein UPF0042 | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.14 | Psyr_0299 | | transcriptional regulator, GntR family | 0.29 | Psyr_4150 | | Uncharacterized P-loop ATPase protein UPF0042 | low | > 86 |
| Bifidobacterium breve UCC2003 | 0.11 | BBR_RS11160 | | FadR family transcriptional regulator | 0.29 | BBR_RS15525 | | RNase adapter RapZ | low | > 34 |
Not shown: 4 genomes with orthologs for GFF3399 only; 25 genomes with orthologs for GFF3820 only