Conservation of cofitness between GFF4449 and GFF2870 in Variovorax sp. SCN45

68 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Variovorax sp. SCN45 1.0 GFF4449 TldD protein, part of TldE/TldD proteolytic complex 1.0 GFF2870 Nicotinate phosphoribosyltransferase (EC 6.3.4.21) 0.92 6
Variovorax sp. OAS795 0.95 ABID97_RS06335 metalloprotease TldD 0.94 ABID97_RS10590 nicotinate phosphoribosyltransferase low > 91
Acidovorax sp. GW101-3H11 0.86 Ac3H11_4036 TldD protein, part of TldE/TldD proteolytic complex 0.81 Ac3H11_2601 Nicotinate phosphoribosyltransferase (EC 2.4.2.11) low > 79
Hydrogenophaga sp. GW460-11-11-14-LB1 0.85 GFF580 TldD protein, part of TldE/TldD proteolytic complex 0.48 GFF1573 Nicotinate phosphoribosyltransferase (EC 2.4.2.11) low > 90
Cupriavidus basilensis FW507-4G11 0.73 RR42_RS05875 protease TldD 0.70 RR42_RS14205 nicotinate phosphoribosyltransferase low > 128
Herbaspirillum seropedicae SmR1 0.73 HSERO_RS07155 peptidase C69 0.68 HSERO_RS08100 nicotinate phosphoribosyltransferase low > 78
Ralstonia sp. UNC404CL21Col 0.72 ABZR87_RS01105 metalloprotease TldD 0.69 ABZR87_RS10040 nicotinate phosphoribosyltransferase low > 80
Ralstonia solanacearum GMI1000 0.72 RS_RS13315 metalloprotease TldD 0.69 RS_RS05105 nicotinate phosphoribosyltransferase low > 80
Burkholderia phytofirmans PsJN 0.72 BPHYT_RS03540 peptidase C69 0.73 BPHYT_RS14535 nicotinate phosphoribosyltransferase low > 109
Ralstonia solanacearum UW163 0.72 UW163_RS08170 metalloprotease TldD 0.69 UW163_RS11790 nicotinate phosphoribosyltransferase
Ralstonia solanacearum IBSBF1503 0.72 RALBFv3_RS05455 metalloprotease TldD 0.69 RALBFv3_RS14325 nicotinate phosphoribosyltransferase low > 76
Paraburkholderia sabiae LMG 24235 0.71 QEN71_RS26555 metalloprotease TldD 0.72 QEN71_RS04445 nicotinate phosphoribosyltransferase low > 153
Ralstonia solanacearum PSI07 0.71 RPSI07_RS11850 metalloprotease TldD 0.70 RPSI07_RS19135 nicotinate phosphoribosyltransferase low > 81
Paraburkholderia bryophila 376MFSha3.1 0.71 H281DRAFT_04688 microcin-processing peptidase 2. Unknown type peptidase. MEROPS family U62 0.73 H281DRAFT_04330 nicotinate phosphoribosyltransferase low > 103
Paraburkholderia graminis OAS925 0.71 ABIE53_000851 TldD protein 0.72 ABIE53_003069 nicotinate phosphoribosyltransferase low > 113
Castellaniella sp019104865 MT123 0.70 ABCV34_RS02590 metalloprotease TldD 0.50 ABCV34_RS02595 nicotinate phosphoribosyltransferase low > 48
Dyella japonica UNC79MFTsu3.2 0.62 ABZR86_RS21715 metalloprotease TldD 0.69 ABZR86_RS00460 nicotinate phosphoribosyltransferase low > 74
Rhodanobacter sp. FW510-T8 0.61 OKGIIK_10280 tldD metalloprotease TldD 0.68 OKGIIK_03545 pncB nicotinate phosphoribosyltransferase low > 52
Rhodanobacter denitrificans MT42 0.59 LRK55_RS03145 metalloprotease TldD 0.67 LRK55_RS14435 nicotinate phosphoribosyltransferase low > 63
Xanthomonas campestris pv. campestris strain 8004 0.59 Xcc-8004.1883.1 TldD protein, part of TldE/TldD proteolytic complex 0.62 Xcc-8004.4407.1 Nicotinate phosphoribosyltransferase (EC 2.4.2.11) low > 74
Rhodanobacter denitrificans FW104-10B01 0.59 LRK54_RS03395 metalloprotease TldD 0.67 LRK54_RS14720 nicotinate phosphoribosyltransferase low > 59
Pseudomonas putida KT2440 0.58 PP_0940 putative protease involved in Microcin B17 maturation and in sensitivity to the DNA gyrase inhibitor LetD 0.45 PP_4868 Nicotinate phosphoribosyltransferase low > 96
Pantoea sp. MT58 0.58 IAI47_02465 metalloprotease TldD 0.37 IAI47_12750 nicotinate phosphoribosyltransferase low > 76
Pseudomonas syringae pv. syringae B728a 0.58 Psyr_4156 microcin-processing peptidase 2, Unknown type peptidase, MEROPS family U62 0.46 Psyr_0595 Nicotinate phosphoribosyltransferase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.58 Psyr_4156 microcin-processing peptidase 2, Unknown type peptidase, MEROPS family U62 0.46 Psyr_0595 Nicotinate phosphoribosyltransferase low > 86
Serratia liquefaciens MT49 0.56 IAI46_22685 metalloprotease TldD 0.38 IAI46_08765 nicotinate phosphoribosyltransferase low > 86
Pseudomonas fluorescens SBW25-INTG 0.56 PFLU_RS04340 metalloprotease TldD 0.45 PFLU_RS02705 nicotinate phosphoribosyltransferase low > 109
Pseudomonas fluorescens SBW25 0.56 PFLU_RS04340 metalloprotease TldD 0.45 PFLU_RS02705 nicotinate phosphoribosyltransferase low > 109
Pseudomonas fluorescens FW300-N2E3 0.56 AO353_05215 protease TldD 0.45 AO353_13320 nicotinate phosphoribosyltransferase low > 101
Pseudomonas simiae WCS417 0.56 PS417_04285 protease TldD 0.45 PS417_02635 nicotinate phosphoribosyltransferase low > 88
Pseudomonas stutzeri RCH2 0.56 Psest_3320 Predicted Zn-dependent proteases and their inactivated homologs 0.46 Psest_1171 nicotinate phosphoribosyltransferase low > 67
Dickeya dadantii 3937 0.56 DDA3937_RS01460 metalloprotease TldD 0.39 DDA3937_RS12890 nicotinate phosphoribosyltransferase low > 74
Pseudomonas fluorescens FW300-N1B4 0.56 Pf1N1B4_1092 TldD protein, part of TldE/TldD proteolytic complex 0.46 Pf1N1B4_1386 Nicotinate phosphoribosyltransferase (EC 2.4.2.11) low > 87
Pseudomonas sp. RS175 0.56 PFR28_00161 Metalloprotease TldD 0.46 PFR28_05149 Nicotinate phosphoribosyltransferase 2 low > 88
Dickeya dianthicola 67-19 0.56 HGI48_RS01380 metalloprotease TldD 0.39 HGI48_RS12960 nicotinate phosphoribosyltransferase low > 71
Pseudomonas fluorescens FW300-N2C3 0.55 AO356_07095 protease TldD 0.46 AO356_08520 nicotinate phosphoribosyltransferase low > 104
Pseudomonas sp. S08-1 0.55 OH686_08580 TldD protein, part of TldE/TldD proteolytic complex 0.45 OH686_03820 nicotinate phosphoribosyltransferase low > 80
Pseudomonas fluorescens FW300-N2E2 0.55 Pf6N2E2_3280 TldD protein, part of TldE/TldD proteolytic complex 0.46 Pf6N2E2_3585 Nicotinate phosphoribosyltransferase (EC 2.4.2.11) low > 103
Dickeya dianthicola ME23 0.55 DZA65_RS01440 metalloprotease TldD 0.40 DZA65_RS13425 nicotinate phosphoribosyltransferase low > 75
Enterobacter sp. TBS_079 0.55 MPMX20_04151 Metalloprotease TldD 0.37 MPMX20_01589 Nicotinate phosphoribosyltransferase low > 85
Pseudomonas fluorescens GW456-L13 0.55 PfGW456L13_5026 TldD protein, part of TldE/TldD proteolytic complex 0.45 PfGW456L13_129 Nicotinate phosphoribosyltransferase (EC 2.4.2.11) low > 87
Klebsiella michiganensis M5al 0.55 BWI76_RS25470 metalloprotease TldD 0.36 BWI76_RS09885 nicotinate phosphoribosyltransferase low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.55 GFF2140 TldD protein, part of TldE/TldD proteolytic complex 0.37 GFF3695 Nicotinate phosphoribosyltransferase (EC 2.4.2.11) low > 78
Escherichia fergusonii Becca 0.55 EFB2_00586 Metalloprotease TldD 0.38 EFB2_03133 Nicotinate phosphoribosyltransferase low > 86
Escherichia coli Nissle 1917 0.55 ECOLIN_RS18595 metalloprotease TldD 0.38 ECOLIN_RS04930 nicotinate phosphoribosyltransferase low > 55
Escherichia coli HS(pFamp)R (ATCC 700891) 0.55 OHPLBJKB_00460 Metalloprotease TldD 0.38 OHPLBJKB_02735 Nicotinate phosphoribosyltransferase low > 73
Escherichia coli ECOR27 0.55 NOLOHH_09555 tldD metalloprotease TldD 0.38 NOLOHH_21925 pncB nicotinate phosphoribosyltransferase low > 75
Pectobacterium carotovorum WPP14 0.55 HER17_RS20140 metalloprotease TldD 0.39 HER17_RS12015 nicotinate phosphoribosyltransferase low > 75
Vibrio cholerae E7946 ATCC 55056 0.55 CSW01_02220 metalloprotease TldD 0.32 CSW01_14505 nicotinate phosphoribosyltransferase low > 62
Escherichia coli ECRC101 0.55 MCAODC_08275 tldD metalloprotease TldD 0.38 MCAODC_24760 pncB nicotinate phosphoribosyltransferase low > 87
Escherichia coli ECRC100 0.55 OKFHMN_17755 tldD metalloprotease TldD 0.38 OKFHMN_05370 pncB nicotinate phosphoribosyltransferase low > 80
Escherichia coli ECRC62 0.55 BNILDI_01980 tldD metalloprotease TldD 0.38 BNILDI_20180 pncB nicotinate phosphoribosyltransferase 0.73 59
Escherichia coli ECRC102 0.55 NIAGMN_15515 tldD metalloprotease TldD 0.38 NIAGMN_03090 pncB nicotinate phosphoribosyltransferase
Escherichia coli ECRC99 0.55 KEDOAH_10395 tldD metalloprotease TldD 0.38 KEDOAH_22365 pncB nicotinate phosphoribosyltransferase
Escherichia coli BW25113 0.55 b3244 tldD predicted peptidase (NCBI) 0.38 b0931 pncB nicotinate phosphoribosyltransferase (NCBI) low > 76
Escherichia coli ECRC98 0.55 JDDGAC_21380 tldD metalloprotease TldD 0.38 JDDGAC_08980 pncB nicotinate phosphoribosyltransferase low > 86
Escherichia coli BL21 0.55 ECD_03104 putative peptidase 0.38 ECD_00935 nicotinate phosphoribosyltransferase low > 61
Escherichia coli ECOR38 0.55 HEPCGN_16620 tldD metalloprotease TldD 0.37 HEPCGN_23155 pncB nicotinate phosphoribosyltransferase low > 87
Enterobacter asburiae PDN3 0.54 EX28DRAFT_3295 Predicted Zn-dependent proteases and their inactivated homologs 0.37 EX28DRAFT_2005 nicotinate phosphoribosyltransferase low > 76
Erwinia tracheiphila SCR3 0.54 LU632_RS21420 tldD metalloprotease TldD 0.36 LU632_RS09925 pncB nicotinate phosphoribosyltransferase
Rahnella sp. WP5 0.54 EX31_RS12265 metalloprotease TldD 0.38 EX31_RS18130 nicotinate phosphoribosyltransferase low > 89
Azospirillum sp. SherDot2 0.52 MPMX19_00882 Metalloprotease TldD 0.19 MPMX19_03477 Nicotinate phosphoribosyltransferase low > 112
Rhizobium sp. OAE497 0.51 ABIE40_RS04050 metalloprotease TldD 0.24 ABIE40_RS00645 nicotinate phosphoribosyltransferase low > 107
Agrobacterium fabrum C58 0.50 Atu0765 TldD 0.23 Atu0213 nicotinate phosphoribosyltransferase low > 89
Sinorhizobium meliloti 1021 0.50 SMc00960 hypothetical protein 0.24 SMc02276 nicotinate phosphoribosyltransferase low > 103
Brevundimonas sp. GW460-12-10-14-LB2 0.49 A4249_RS10860 metalloprotease TldD 0.21 A4249_RS08365 nicotinate phosphoribosyltransferase low > 48
Phaeobacter inhibens DSM 17395 0.49 PGA1_c06240 protein TldD 0.19 PGA1_c32130 nicotinate phosphoribosyltransferase PncB low > 62
Dinoroseobacter shibae DFL-12 0.48 Dshi_1139 peptidase U62 modulator of DNA gyrase (RefSeq) 0.24 Dshi_3345 nicotinate phosphoribosyltransferase (RefSeq)
Bacteroides thetaiotaomicron VPI-5482 0.35 BT3648 putative modulator of DNA gyrase (NCBI ptt file) 0.25 BT1913 nicotinate phosphoribosyltransferase (NCBI ptt file) low > 81

Not shown: 21 genomes with orthologs for GFF4449 only; 3 genomes with orthologs for GFF2870 only