Conservation of cofitness between ECD_02743 and ECD_04113 in Escherichia coli BL21

67 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_02743 5-formyltetrahydrofolate cyclo-ligase family protein 1.0 ECD_04113 aspartate carbamoyltransferase, catalytic subunit 0.47 40
Escherichia fergusonii Becca 1.00 EFB2_00991 5-formyltetrahydrofolate cyclo-ligase 1.00 EFB2_04288 Aspartate carbamoyltransferase catalytic subunit low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00804 5-formyltetrahydrofolate cyclo-ligase 1.00 OHPLBJKB_03789 Aspartate carbamoyltransferase catalytic subunit low > 73
Escherichia coli ECRC62 1.00 BNILDI_09930 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 BNILDI_07385 pyrB aspartate carbamoyltransferase low > 75
Escherichia coli ECRC100 1.00 OKFHMN_19485 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 OKFHMN_11865 pyrB aspartate carbamoyltransferase 0.75 63
Escherichia coli ECOR27 1.00 NOLOHH_11395 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 NOLOHH_04125 pyrB aspartate carbamoyltransferase low > 75
Escherichia coli ECRC99 1.00 KEDOAH_08655 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 KEDOAH_16290 pyrB aspartate carbamoyltransferase — —
Escherichia coli ECRC101 1.00 MCAODC_10005 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 MCAODC_02370 pyrB aspartate carbamoyltransferase low > 87
Escherichia coli ECRC102 1.00 NIAGMN_17250 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 NIAGMN_09715 pyrB aspartate carbamoyltransferase — —
Escherichia coli ECRC98 1.00 JDDGAC_23125 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 JDDGAC_15505 pyrB aspartate carbamoyltransferase low > 86
Escherichia coli Nissle 1917 0.99 ECOLIN_RS16205 5-formyltetrahydrofolate cyclo-ligase 1.00 ECOLIN_RS24625 aspartate carbamoyltransferase low > 55
Escherichia coli BW25113 0.99 b2912 ygfA putative ligase (VIMSS) 1.00 b4245 pyrB aspartate carbamoyltransferase catalytic subunit (NCBI) low > 76
Escherichia coli ECOR38 0.99 HEPCGN_18775 ygfA 5-formyltetrahydrofolate cyclo-ligase 1.00 HEPCGN_10060 pyrB aspartate carbamoyltransferase low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.85 GFF3012 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) 0.96 GFF930 Aspartate carbamoyltransferase (EC 2.1.3.2) low > 78
Enterobacter sp. TBS_079 0.82 MPMX20_03770 5-formyltetrahydrofolate cyclo-ligase 0.92 MPMX20_00544 Aspartate carbamoyltransferase catalytic subunit low > 85
Klebsiella michiganensis M5al 0.79 BWI76_RS23915 5-formyltetrahydrofolate cyclo-ligase 0.94 BWI76_RS02995 aspartate carbamoyltransferase 0.22 38
Enterobacter asburiae PDN3 0.78 EX28DRAFT_2964 5,10-methenyltetrahydrofolate synthetase 0.93 EX28DRAFT_3446 aspartate carbamoyltransferase (EC 2.1.3.2) — —
Pectobacterium carotovorum WPP14 0.69 HER17_RS19095 5-formyltetrahydrofolate cyclo-ligase 0.87 HER17_RS19510 aspartate carbamoyltransferase low > 75
Serratia liquefaciens MT49 0.66 IAI46_20895 5-formyltetrahydrofolate cyclo-ligase 0.90 IAI46_02275 aspartate carbamoyltransferase low > 86
Dickeya dadantii 3937 0.64 DDA3937_RS02410 5-formyltetrahydrofolate cyclo-ligase 0.86 DDA3937_RS01925 aspartate carbamoyltransferase low > 74
Rahnella sp. WP5 0.64 EX31_RS21480 5-formyltetrahydrofolate cyclo-ligase 0.88 EX31_RS12785 aspartate carbamoyltransferase low > 89
Dickeya dianthicola 67-19 0.62 HGI48_RS02370 5-formyltetrahydrofolate cyclo-ligase 0.86 HGI48_RS01900 aspartate carbamoyltransferase low > 71
Erwinia tracheiphila SCR3 0.60 LU632_RS05860 5-formyltetrahydrofolate cyclo-ligase 0.86 LU632_RS20950 pyrB aspartate carbamoyltransferase — —
Shewanella loihica PV-4 0.59 Shew_3069 5-formyltetrahydrofolate cyclo-ligase (RefSeq) 0.34 Shew_1013 aspartate carbamoyltransferase (RefSeq) 0.35 55
Dickeya dianthicola ME23 0.59 DZA65_RS02475 5-formyltetrahydrofolate cyclo-ligase 0.87 DZA65_RS01970 aspartate carbamoyltransferase 0.65 47
Pantoea sp. MT58 0.59 IAI47_03730 5-formyltetrahydrofolate cyclo-ligase 0.87 IAI47_16860 aspartate carbamoyltransferase low > 76
Vibrio cholerae E7946 ATCC 55056 0.57 CSW01_12545 5-formyltetrahydrofolate cyclo-ligase 0.74 CSW01_12725 aspartate carbamoyltransferase low > 62
Shewanella oneidensis MR-1 0.56 SO0774 5-formyltetrahydrofolate cyclo-ligase family protein (NCBI ptt file) 0.35 SO1301 pyrB aspartate carbamoyltransferase (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.55 Shewana3_3506 5-formyltetrahydrofolate cyclo-ligase (RefSeq) 0.35 Shewana3_3070 aspartate carbamoyltransferase (RefSeq) low > 73
Marinobacter adhaerens HP15 0.32 HP15_3211 5-formyltetrahydrofolate cyclo-ligase 0.23 HP15_3507 aspartate carbamoyltransferase low > 73
Pseudomonas stutzeri RCH2 0.30 Psest_0170 5,10-methenyltetrahydrofolate synthetase 0.23 Psest_0291 aspartate carbamoyltransferase — —
Pseudomonas fluorescens FW300-N1B4 0.30 Pf1N1B4_2225 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) 0.23 Pf1N1B4_2347 Aspartate carbamoyltransferase (EC 2.1.3.2) — —
Pseudomonas fluorescens SBW25 0.29 PFLU_RS28965 5-formyltetrahydrofolate cyclo-ligase 0.23 PFLU_RS28345 aspartate carbamoyltransferase — —
Pseudomonas simiae WCS417 0.29 PS417_27305 5-formyltetrahydrofolate cyclo-ligase 0.23 PS417_26700 aspartate carbamoyltransferase catalytic subunit — —
Pseudomonas fluorescens FW300-N2E3 0.29 AO353_08780 5-formyltetrahydrofolate cyclo-ligase 0.23 AO353_08135 aspartate carbamoyltransferase catalytic subunit — —
Pseudomonas fluorescens SBW25-INTG 0.29 PFLU_RS28965 5-formyltetrahydrofolate cyclo-ligase 0.23 PFLU_RS28345 aspartate carbamoyltransferase — —
Pseudomonas fluorescens GW456-L13 0.28 PfGW456L13_892 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) 0.23 PfGW456L13_1016 Aspartate carbamoyltransferase (EC 2.1.3.2) — —
Pseudomonas sp. S08-1 0.28 OH686_11225 5-formyltetrahydrofolate cyclo-ligase 0.23 OH686_10940 aspartate carbamoyltransferase — —
Pseudomonas putida KT2440 0.27 PP_5203 5-formyltetrahydrofolate cyclo-ligase 0.23 PP_4998 Aspartate carbamoyltransferase — —
Pseudomonas syringae pv. syringae B728a 0.27 Psyr_0317 5-formyltetrahydrofolate cyclo-ligase 0.22 Psyr_0482 aspartate carbamoyltransferase — —
Pseudomonas fluorescens FW300-N2E2 0.27 Pf6N2E2_4476 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) 0.23 Pf6N2E2_4606 Aspartate carbamoyltransferase (EC 2.1.3.2) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.27 Psyr_0317 5-formyltetrahydrofolate cyclo-ligase 0.22 Psyr_0482 aspartate carbamoyltransferase — —
Pseudomonas sp. RS175 0.27 PFR28_04325 5-formyltetrahydrofolate cyclo-ligase 0.23 PFR28_04237 Aspartate carbamoyltransferase — —
Pseudomonas fluorescens FW300-N2C3 0.27 AO356_12990 5-formyltetrahydrofolate cyclo-ligase 0.23 AO356_13450 aspartate carbamoyltransferase catalytic subunit — —
Acinetobacter radioresistens SK82 0.25 MPMX26_02298 5-formyltetrahydrofolate cyclo-ligase 0.23 MPMX26_01099 Aspartate carbamoyltransferase 0.80 6
Lysobacter sp. OAE881 0.24 ABIE51_RS17355 5-formyltetrahydrofolate cyclo-ligase 0.22 ABIE51_RS16015 aspartate carbamoyltransferase catalytic subunit low > 62
Agrobacterium fabrum C58 0.23 Atu3731 5-formyltetrahydrofolate cyclo-ligase 0.21 Atu1308 aspartate carbamoyl transferase catalytic subunit 0.79 43
Xanthomonas campestris pv. campestris strain 8004 0.22 Xcc-8004.1138.1 5-formyltetrahydrofolate cyclo-ligase (EC 6.3.3.2) 0.22 Xcc-8004.1722.1 Aspartate carbamoyltransferase (EC 2.1.3.2) — —
Sinorhizobium meliloti 1021 0.21 SMc03974 hypothetical protein 0.23 SMc01360 aspartate carbamoyltransferase catalytic subunit low > 103
Parabacteroides merdae CL09T00C40 0.21 HMPREF1078_RS14635 5-formyltetrahydrofolate cyclo-ligase 0.51 HMPREF1078_RS01350 aspartate carbamoyltransferase — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.20 CA264_15880 5-formyltetrahydrofolate cyclo-ligase 0.22 CA264_20465 aspartate carbamoyltransferase low > 74
Desulfovibrio vulgaris Miyazaki F 0.20 DvMF_2318 5-formyltetrahydrofolate cyclo-ligase (RefSeq) 0.17 DvMF_1425 pyrB aspartate carbamoyltransferase catalytic subunit (RefSeq) 0.43 46
Rhizobium sp. OAE497 0.20 ABIE40_RS15645 5-formyltetrahydrofolate cyclo-ligase 0.21 ABIE40_RS07385 aspartate carbamoyltransferase catalytic subunit — —
Rhodanobacter denitrificans MT42 0.19 LRK55_RS11395 5-formyltetrahydrofolate cyclo-ligase 0.23 LRK55_RS03990 aspartate carbamoyltransferase catalytic subunit — —
Rhodanobacter denitrificans FW104-10B01 0.19 LRK54_RS11670 5-formyltetrahydrofolate cyclo-ligase 0.23 LRK54_RS04220 aspartate carbamoyltransferase catalytic subunit — —
Rhodanobacter sp. FW510-T8 0.19 OKGIIK_12225 5-formyltetrahydrofolate cyclo-ligase 0.22 OKGIIK_11095 pyrB aspartate carbamoyltransferase catalytic subunit — —
Bacteroides ovatus ATCC 8483 0.18 BACOVA_05091 5-formyltetrahydrofolate cyclo-ligase 0.49 BACOVA_02450 aspartate carbamoyltransferase — —
Caulobacter crescentus NA1000 Δfur 0.18 CCNA_03354 5-formyltetrahydrofolate cyclo-ligase 0.20 CCNA_02525 aspartate carbamoyltransferase low > 67
Caulobacter crescentus NA1000 0.18 CCNA_03354 5-formyltetrahydrofolate cyclo-ligase 0.20 CCNA_02525 aspartate carbamoyltransferase low > 66
Azospirillum brasilense Sp245 0.18 AZOBR_RS09025 5-formyltetrahydrofolate cyclo-ligase 0.23 AZOBR_RS20575 aspartate carbamoyltransferase low > 97
Phocaeicola dorei CL03T12C01 0.18 ABI39_RS13145 5-formyltetrahydrofolate cyclo-ligase 0.48 ABI39_RS17400 aspartate carbamoyltransferase — —
Rhodopseudomonas palustris CGA009 0.18 TX73_023120 5-formyltetrahydrofolate cyclo-ligase 0.19 TX73_016120 aspartate carbamoyltransferase catalytic subunit — —
Phocaeicola vulgatus CL09T03C04 0.18 HMPREF1058_RS17145 5-formyltetrahydrofolate cyclo-ligase 0.48 HMPREF1058_RS03820 aspartate carbamoyltransferase — —
Bacteroides stercoris CC31F 0.17 HMPREF1181_RS06170 5-formyltetrahydrofolate cyclo-ligase 0.48 HMPREF1181_RS14990 aspartate carbamoyltransferase low > 56
Dyella japonica UNC79MFTsu3.2 0.15 ABZR86_RS11995 5-formyltetrahydrofolate cyclo-ligase 0.22 ABZR86_RS10390 aspartate carbamoyltransferase catalytic subunit — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.15 Echvi_1511 5,10-methenyltetrahydrofolate synthetase 0.23 Echvi_4661 aspartate carbamoyltransferase — —
Cupriavidus basilensis FW507-4G11 0.14 RR42_RS01400 5-formyltetrahydrofolate cyclo-ligase 0.22 RR42_RS15860 aspartate carbamoyltransferase catalytic subunit — —
Phaeobacter inhibens DSM 17395 0.13 PGA1_c21820 5-formyltetrahydrofolate cycloligase-like protein 0.22 PGA1_c03060 aspartate carbamoyltransferase PyrB low > 62

Not shown: 2 genomes with orthologs for ECD_02743 only; 27 genomes with orthologs for ECD_04113 only