| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Escherichia coli BL21 | 1.0 | ECD_04103 | | putative antibiotic peptide MccB17 maturation peptidase | 1.0 | ECD_02540 | | multidrug efflux system | low | > 61 |
| Escherichia coli ECRC101 | 1.00 | MCAODC_02430 | pmbA | metalloprotease PmbA | 1.00 | MCAODC_11305 | emrA | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | low | > 87 |
| Escherichia coli BW25113 | 1.00 | b4235 | pmbA | predicted peptidase required for the maturation and secretion of the antibiotic peptide MccB17 (NCBI) | 1.00 | b2685 | emrA | multidrug efflux system (NCBI) | low | > 76 |
| Escherichia coli ECOR27 | 1.00 | NOLOHH_04185 | pmbA | metalloprotease PmbA | 1.00 | NOLOHH_12620 | emrA | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | low | > 75 |
| Escherichia coli ECRC99 | 1.00 | KEDOAH_16230 | pmbA | metalloprotease PmbA | 1.00 | KEDOAH_07355 | emrA | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 1.00 | OHPLBJKB_03800 | | Metalloprotease PmbA | 1.00 | OHPLBJKB_01048 | | Multidrug export protein EmrA | low | > 73 |
| Escherichia coli ECRC62 | 1.00 | BNILDI_07325 | pmbA | metalloprotease PmbA | 1.00 | BNILDI_11180 | emrA | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | low | > 75 |
| Escherichia coli ECRC98 | 1.00 | JDDGAC_15565 | pmbA | metalloprotease PmbA | 1.00 | JDDGAC_24445 | emrA | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | 0.73 | 44 |
| Escherichia coli ECRC102 | 1.00 | NIAGMN_09775 | pmbA | metalloprotease PmbA | 1.00 | NIAGMN_18550 | emrA | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | — | — |
| Escherichia coli ECOR38 | 1.00 | HEPCGN_10125 | pmbA | metalloprotease PmbA | 1.00 | HEPCGN_19975 | emrA | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | low | > 87 |
| Escherichia coli ECRC100 | 1.00 | OKFHMN_11925 | pmbA | metalloprotease PmbA | 1.00 | OKFHMN_20780 | emrA | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | low | > 80 |
| Escherichia fergusonii Becca | 0.99 | EFB2_04298 | | Metalloprotease PmbA | 1.00 | EFB2_01243 | | Multidrug export protein EmrA | low | > 86 |
| Escherichia coli Nissle 1917 | 0.99 | ECOLIN_RS24570 | | metalloprotease PmbA | 1.00 | ECOLIN_RS14965 | | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | low | > 55 |
| Enterobacter sp. TBS_079 | 0.96 | MPMX20_00517 | | Metalloprotease PmbA | 0.87 | MPMX20_03563 | | Multidrug export protein EmrA | low | > 85 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.96 | GFF904 | | TldE protein, part of TldE/TldD proteolytic complex | 0.89 | GFF1592 | | Multidrug resistance protein A | low | > 78 |
| Enterobacter asburiae PDN3 | 0.96 | EX28DRAFT_3422 | | Predicted Zn-dependent proteases and their inactivated homologs | 0.85 | EX28DRAFT_2768 | | efflux pump membrane protein (multidrug resistance protein A) | low | > 76 |
| Klebsiella michiganensis M5al | 0.94 | BWI76_RS02850 | | metalloprotease PmbA | 0.82 | BWI76_RS22095 | | multidrug export protein EmrA | low | > 92 |
| Serratia liquefaciens MT49 | 0.86 | IAI46_22575 | | metalloprotease PmbA | 0.70 | IAI46_20000 | | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | low | > 86 |
| Rahnella sp. WP5 | 0.85 | EX31_RS12320 | | metalloprotease PmbA | 0.71 | EX31_RS13655 | | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | low | > 89 |
| Pectobacterium carotovorum WPP14 | 0.84 | HER17_RS20090 | | metalloprotease PmbA | 0.70 | HER17_RS04465 | | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | low | > 75 |
| Pantoea sp. MT58 | 0.84 | IAI47_02765 | | metalloprotease PmbA | 0.71 | IAI47_04500 | | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | low | > 76 |
| Dickeya dadantii 3937 | 0.81 | DDA3937_RS01500 | | metalloprotease PmbA | 0.68 | DDA3937_RS16760 | | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | low | > 74 |
| Dickeya dianthicola 67-19 | 0.81 | HGI48_RS01415 | | metalloprotease PmbA | 0.66 | HGI48_RS16830 | | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | low | > 71 |
| Dickeya dianthicola ME23 | 0.81 | DZA65_RS01480 | | metalloprotease PmbA | 0.67 | DZA65_RS17905 | | multidrug efflux MFS transporter periplasmic adaptor subunit EmrA | low | > 75 |
| Pseudomonas sp. RS175 | 0.48 | PFR28_00163 | | Metalloprotease PmbA | 0.41 | PFR28_02748 | | Multidrug export protein EmrA | low | > 88 |
| Pseudomonas fluorescens FW300-N2C3 | 0.48 | AO356_07085 | | peptidase PmbA | 0.38 | AO356_01030 | | hemolysin D | low | > 104 |
| Pseudomonas fluorescens SBW25 | 0.48 | PFLU_RS04350 | | metalloprotease PmbA | 0.41 | PFLU_RS18900 | | HlyD family efflux transporter periplasmic adaptor subunit | low | > 109 |
| Pseudomonas fluorescens FW300-N2E2 | 0.48 | Pf6N2E2_3278 | | TldE protein, part of TldE/TldD proteolytic complex | 0.41 | Pf6N2E2_148 | | Membrane fusion component of tripartite multidrug resistance system | low | > 103 |
| Pseudomonas fluorescens SBW25-INTG | 0.48 | PFLU_RS04350 | | metalloprotease PmbA | 0.41 | PFLU_RS18900 | | HlyD family efflux transporter periplasmic adaptor subunit | low | > 109 |
| Pseudomonas simiae WCS417 | 0.47 | PS417_04295 | | peptidase PmbA | 0.40 | PS417_16915 | | hemolysin D | low | > 88 |
| Pseudomonas putida KT2440 | 0.47 | PP_0942 | | regulatory protease | 0.40 | PP_3549 | | multidrug efflux transport system - membrane fusion protein | low | > 96 |
| Pseudomonas fluorescens FW300-N1B4 | 0.47 | Pf1N1B4_1090 | | TldE protein, part of TldE/TldD proteolytic complex | 0.41 | Pf1N1B4_4001 | | Membrane fusion component of tripartite multidrug resistance system | low | > 87 |
| Pseudomonas fluorescens FW300-N2E3 | 0.47 | AO353_05205 | | peptidase PmbA | 0.40 | AO353_27845 | | hemolysin D | low | > 101 |
| Pseudomonas fluorescens GW456-L13 | 0.47 | PfGW456L13_5024 | | TldE protein, part of TldE/TldD proteolytic complex | 0.39 | PfGW456L13_2605 | | Membrane fusion component of tripartite multidrug resistance system | low | > 87 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.46 | Psyr_4154 | | microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 | 0.42 | Psyr_1730 | | Secretion protein HlyD | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.46 | Psyr_4154 | | microcin-processing peptidase 1, Unknown type peptidase, MEROPS family U62 | 0.42 | Psyr_1730 | | Secretion protein HlyD | low | > 86 |
| Herbaspirillum seropedicae SmR1 | 0.45 | HSERO_RS09265 | | peptidase C69 | 0.40 | HSERO_RS13570 | | hemolysin D | low | > 78 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.45 | Xcc-8004.1885.1 | | TldE protein, part of TldE/TldD proteolytic complex | 0.38 | Xcc-8004.3525.1 | | Membrane fusion component of tripartite multidrug resistance system | low | > 74 |
| Variovorax sp. OAS795 | 0.45 | ABID97_RS20695 | | metalloprotease PmbA | 0.40 | ABID97_RS20395 | | efflux RND transporter periplasmic adaptor subunit | low | > 91 |
| Dyella japonica UNC79MFTsu3.2 | 0.45 | ABZR86_RS21700 | | metalloprotease PmbA | 0.40 | ABZR86_RS14770 | | HlyD family efflux transporter periplasmic adaptor subunit | low | > 74 |
| Rhodanobacter sp. FW510-T8 | 0.45 | OKGIIK_10260 | pmbA | metalloprotease PmbA | 0.41 | OKGIIK_08530 | emrA | EmrA/EmrK family multidrug efflux transporter periplasmic adaptor subunit | low | > 52 |
| Pseudomonas sp. S08-1 | 0.45 | OH686_08570 | | TldE protein, part of TldE/TldD proteolytic complex | 0.18 | OH686_04565 | | Membrane fusion component of MSF-type tripartite multidrug efflux system | low | > 80 |
| Variovorax sp. SCN45 | 0.45 | GFF4697 | | TldE protein, part of TldE/TldD proteolytic complex | 0.40 | GFF4770 | | Multidrug efflux system EmrAB-OMF, membrane fusion component EmrA | low | > 127 |
| Rhodanobacter denitrificans FW104-10B01 | 0.44 | LRK54_RS03375 | | metalloprotease PmbA | 0.41 | LRK54_RS07785 | | HlyD family efflux transporter periplasmic adaptor subunit | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.44 | LRK55_RS03125 | | metalloprotease PmbA | 0.41 | LRK55_RS07515 | | HlyD family efflux transporter periplasmic adaptor subunit | low | > 63 |
| Acidovorax sp. GW101-3H11 | 0.44 | Ac3H11_3262 | | TldE protein, part of TldE/TldD proteolytic complex | 0.40 | Ac3H11_2351 | | Membrane fusion component of tripartite multidrug resistance system | low | > 79 |
| Ralstonia solanacearum IBSBF1503 | 0.43 | RALBFv3_RS13965 | | metalloprotease PmbA | 0.43 | RALBFv3_RS15700 | | hemolysin D | low | > 76 |
| Ralstonia sp. UNC404CL21Col | 0.43 | ABZR87_RS09660 | | metalloprotease PmbA | 0.42 | ABZR87_RS11230 | | HlyD family secretion protein | low | > 80 |
| Paraburkholderia graminis OAS925 | 0.43 | ABIE53_003116 | | PmbA protein | 0.45 | ABIE53_002457 | | membrane fusion protein (multidrug efflux system) | low | > 113 |
| Ralstonia solanacearum PSI07 | 0.43 | RPSI07_RS19505 | | metalloprotease PmbA | 0.41 | RPSI07_RS17655 | | hemolysin D | low | > 81 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.43 | H281DRAFT_04304 | | microcin-processing peptidase 1. Unknown type peptidase. MEROPS family U62 | 0.45 | H281DRAFT_05108 | | membrane fusion protein, multidrug efflux system | low | > 103 |
| Burkholderia phytofirmans PsJN | 0.43 | BPHYT_RS14705 | | peptidase C69 | 0.46 | BPHYT_RS08090 | | hemolysin D | low | > 109 |
| Paraburkholderia sabiae LMG 24235 | 0.43 | QEN71_RS04270 | | metalloprotease PmbA | 0.47 | QEN71_RS23080 | | EmrA/EmrK family multidrug efflux transporter periplasmic adaptor subunit | low | > 153 |
| Castellaniella sp019104865 MT123 | 0.42 | ABCV34_RS10610 | | metalloprotease PmbA | 0.39 | ABCV34_RS05945 | | HlyD family efflux transporter periplasmic adaptor subunit | low | > 48 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.41 | GFF3655 | | TldE protein, part of TldE/TldD proteolytic complex | 0.35 | GFF3756 | | Membrane fusion component of tripartite multidrug resistance system | low | > 90 |
| Lysobacter sp. OAE881 | 0.41 | ABIE51_RS06805 | | metalloprotease PmbA | 0.39 | ABIE51_RS07710 | | efflux RND transporter periplasmic adaptor subunit | low | > 62 |
| Ralstonia solanacearum GMI1000 | 0.41 | RS_RS04700 | | metalloprotease PmbA | 0.41 | RS_RS06480 | | hemolysin D | low | > 80 |
| Cupriavidus basilensis FW507-4G11 | 0.41 | RR42_RS14750 | | peptidase PMbA | 0.44 | RR42_RS12825 | | hemolysin D | low | > 128 |
| Sphingomonas koreensis DSMZ 15582 | 0.30 | Ga0059261_0810 | | Predicted Zn-dependent proteases and their inactivated homologs | 0.21 | Ga0059261_4006 | | Multidrug resistance efflux pump | low | > 68 |
| Rhodopseudomonas palustris CGA009 | 0.29 | TX73_005930 | | TldD/PmbA family protein | 0.34 | TX73_019155 | | efflux RND transporter periplasmic adaptor subunit | low | > 86 |
| Rhodospirillum rubrum S1H | 0.29 | Rru_A0575 | | Peptidase U62, modulator of DNA gyrase (NCBI) | 0.41 | Rru_A0859 | | Secretion protein HlyD (NCBI) | low | > 58 |
| Caulobacter crescentus NA1000 | 0.28 | CCNA_00311 | | Zn-dependent protease family protein | 0.22 | CCNA_03830 | | multidrug resistance protein A, efflux pump | low | > 66 |
| Caulobacter crescentus NA1000 Δfur | 0.28 | CCNA_00311 | | Zn-dependent protease family protein | 0.22 | CCNA_03830 | | multidrug resistance protein A, efflux pump | low | > 67 |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.28 | A4249_RS09195 | | TldD/PmbA family protein | 0.19 | A4249_RS14990 | | HlyD family secretion protein | low | > 48 |
| Bacteroides thetaiotaomicron VPI-5482 | 0.20 | BT3649 | | putative modulator of DNA gyrase (NCBI ptt file) | 0.17 | BT2794 | | bile salt tripartite efflux system, membrane fusion component (from data) | low | > 81 |
| Bacteroides stercoris CC31F | 0.17 | HMPREF1181_RS03170 | | TldD/PmbA family protein | 0.16 | HMPREF1181_RS03700 | | HlyD family secretion protein | low | > 56 |
Not shown: 23 genomes with orthologs for ECD_04103 only; 2 genomes with orthologs for ECD_02540 only