Conservation of cofitness between ECD_02776 and ECD_01770 in Escherichia coli BL21

58 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_02776 16S rRNA m(3)U1498 methyltransferase, SAM-dependent 1.0 ECD_01770 D-malate oxidase, NAD-dependent; putative tartrate dehydrogenase 0.75 9
Escherichia coli ECOR38 1.00 HEPCGN_18585 Ribosomal RNA small subunit methyltransferase E 0.99 HEPCGN_05015 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase low > 87
Escherichia coli ECRC98 1.00 JDDGAC_22910 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.99 JDDGAC_01200 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase low > 86
Escherichia coli ECRC99 1.00 KEDOAH_08860 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.99 KEDOAH_01485 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase — —
Escherichia coli ECRC101 1.00 MCAODC_09800 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.99 MCAODC_18785 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00772 Ribosomal RNA small subunit methyltransferase E 1.00 OHPLBJKB_01933 D-malate dehydrogenase [decarboxylating] low > 73
Escherichia coli ECRC102 1.00 NIAGMN_17045 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.99 NIAGMN_01440 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase — —
Escherichia coli ECOR27 1.00 NOLOHH_11150 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.99 NOLOHH_17145 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase low > 75
Escherichia coli BW25113 1.00 b2946 yggJ orf, hypothetical protein (VIMSS) 1.00 b1800 yeaU predicted dehydrogenase (NCBI) low > 76
Escherichia coli ECRC100 1.00 OKFHMN_19280 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.99 OKFHMN_26625 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase low > 80
Escherichia coli ECRC62 1.00 BNILDI_09730 rsmE 16S rRNA (uracil(1498)-N(3))-methyltransferase 1.00 BNILDI_15930 dmlA multifunctional D-malate/3-isopropylmalate/tartarate dehydrogenase low > 75
Klebsiella michiganensis M5al 0.86 BWI76_RS24070 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.89 BWI76_RS10680 tartrate dehydrogenase low > 92
Serratia liquefaciens MT49 0.83 IAI46_21385 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.84 IAI46_21025 tartrate dehydrogenase low > 86
Pantoea sp. MT58 0.82 IAI47_03620 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.67 IAI47_17525 tartrate dehydrogenase low > 76
Dickeya dadantii 3937 0.81 DDA3937_RS18555 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.66 DDA3937_RS04645 tartrate dehydrogenase low > 74
Dickeya dianthicola 67-19 0.79 HGI48_RS18490 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.64 HGI48_RS04605 tartrate dehydrogenase low > 71
Dickeya dianthicola ME23 0.79 DZA65_RS19625 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.65 DZA65_RS04525 tartrate dehydrogenase low > 75
Shewanella loihica PV-4 0.65 Shew_3224 hypothetical protein (RefSeq) 0.27 Shew_2760 isocitrate dehydrogenase (RefSeq) — —
Marinobacter adhaerens HP15 0.46 HP15_2926 ribosomal RNA small subunit methyltransferase E 0.35 HP15_817 3-isopropylmalate dehydrogenase low > 73
Alteromonas macleodii MIT1002 0.45 MIT1002_03054 Ribosomal RNA small subunit methyltransferase E 0.27 MIT1002_00983 Isocitrate dehydrogenase [NADP] low > 70
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_08050 16S rRNA methyltransferase 0.80 AO353_28225 tartrate dehydrogenase low > 101
Pseudomonas fluorescens SBW25 0.42 PFLU_RS28200 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.78 PFLU_RS19735 tartrate dehydrogenase low > 109
Pseudomonas fluorescens SBW25-INTG 0.42 PFLU_RS28200 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.78 PFLU_RS19735 tartrate dehydrogenase low > 109
Pseudomonas fluorescens FW300-N2E2 0.41 Pf6N2E2_4630 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) 0.78 Pf6N2E2_369 Tartrate dehydrogenase (EC 1.1.1.93) @ Tartrate decarboxylase (EC 4.1.1.73) @ D-malic enzyme (EC 1.1.1.83) low > 103
Pseudomonas fluorescens FW300-N2C3 0.41 AO356_13565 16S rRNA methyltransferase 0.78 AO356_26735 tartrate dehydrogenase low > 104
Pseudomonas fluorescens FW300-N1B4 0.40 Pf1N1B4_2376 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) 0.79 Pf1N1B4_4932 Tartrate dehydrogenase (EC 1.1.1.93) / Tartrate decarboxylase (EC 4.1.1.73) / D-malic enzyme (EC 1.1.1.83) — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.40 Psyr_0453 16S rRNA m(3)U-1498 methyltransferase 0.77 Psyr_2396 Tartrate dehydrogenase low > 86
Pseudomonas syringae pv. syringae B728a 0.40 Psyr_0453 16S rRNA m(3)U-1498 methyltransferase 0.77 Psyr_2396 Tartrate dehydrogenase low > 86
Dyella japonica UNC79MFTsu3.2 0.38 ABZR86_RS10230 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.28 ABZR86_RS00740 isocitrate dehydrogenase — —
Xanthomonas campestris pv. campestris strain 8004 0.37 Xcc-8004.1558.1 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) 0.27 Xcc-8004.4057.1 Isocitrate dehydrogenase [NAD] (EC 1.1.1.41) — —
Rhodanobacter denitrificans FW104-10B01 0.36 LRK54_RS04160 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.27 LRK54_RS15050 isocitrate dehydrogenase — —
Rhodanobacter denitrificans MT42 0.35 LRK55_RS03930 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.27 LRK55_RS14765 isocitrate dehydrogenase — —
Lysobacter sp. OAE881 0.35 ABIE51_RS05260 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.27 ABIE51_RS14200 isocitrate dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.34 RALBFv3_RS05880 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.74 RALBFv3_RS18940 tartrate dehydrogenase — —
Ralstonia solanacearum UW163 0.34 UW163_RS07745 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.74 UW163_RS20190 tartrate dehydrogenase — —
Burkholderia phytofirmans PsJN 0.34 BPHYT_RS16855 16S rRNA methyltransferase 0.71 BPHYT_RS30235 tartrate dehydrogenase low > 109
Ralstonia solanacearum PSI07 0.34 RPSI07_RS11365 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.74 RPSI07_RS04610 tartrate dehydrogenase low > 81
Cupriavidus basilensis FW507-4G11 0.33 RR42_RS17590 16S rRNA methyltransferase 0.66 RR42_RS02600 tartrate dehydrogenase low > 128
Rhodanobacter sp. FW510-T8 0.33 OKGIIK_11035 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.26 OKGIIK_03810 leuB isocitrate dehydrogenase — —
Ralstonia solanacearum GMI1000 0.33 RS_RS13825 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.72 RS_RS24845 tartrate dehydrogenase low > 80
Paraburkholderia bryophila 376MFSha3.1 0.33 H281DRAFT_06311 16S rRNA (uracil1498-N3)-methyltransferase 0.70 H281DRAFT_06345 tartrate dehydrogenase/decarboxylase / D-malate dehydrogenase low > 103
Ralstonia sp. UNC404CL21Col 0.33 ABZR87_RS01505 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.74 ABZR87_RS21505 tartrate dehydrogenase low > 80
Paraburkholderia sabiae LMG 24235 0.33 QEN71_RS27020 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.72 QEN71_RS32005 tartrate dehydrogenase low > 153
Acidovorax sp. GW101-3H11 0.32 Ac3H11_4323 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) 0.73 Ac3H11_3259 Tartrate dehydrogenase (EC 1.1.1.93) @ Tartrate decarboxylase (EC 4.1.1.73) @ D-malic enzyme (EC 1.1.1.83) low > 79
Paraburkholderia graminis OAS925 0.32 ABIE53_003540 16S rRNA (uracil1498-N3)-methyltransferase 0.71 ABIE53_005023 tartrate dehydrogenase/decarboxylase/D-malate dehydrogenase low > 113
Variovorax sp. SCN45 0.30 GFF3255 16S rRNA (uracil(1498)-N(3))-methyltransferase (EC 2.1.1.193) 0.65 GFF2854 D-malate dehydrogenase [decarboxylating] (EC 1.1.1.83) low > 127
Herbaspirillum seropedicae SmR1 0.29 HSERO_RS07110 16S rRNA methyltransferase 0.75 HSERO_RS07390 tartrate dehydrogenase low > 78
Hydrogenophaga sp. GW460-11-11-14-LB1 0.29 GFF2462 Ribosomal RNA small subunit methyltransferase E (EC 2.1.1.-) 0.65 GFF3852 Tartrate dehydrogenase (EC 1.1.1.93) / Tartrate decarboxylase (EC 4.1.1.73) / D-malic enzyme (EC 1.1.1.83) low > 90
Castellaniella sp019104865 MT123 0.27 ABCV34_RS15445 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.72 ABCV34_RS14695 tartrate dehydrogenase low > 48
Phaeobacter inhibens DSM 17395 0.19 PGA1_c02950 RNA methyltransferase-like protein 0.55 PGA1_c17990 D-malate dehydrogenase low > 62
Dinoroseobacter shibae DFL-12 0.18 Dshi_3099 protein of unknown function DUF558 (RefSeq) 0.66 Dshi_0775 tartrate dehydrogenase (RefSeq) low > 64
Azospirillum sp. SherDot2 0.18 MPMX19_00577 Ribosomal RNA small subunit methyltransferase E 0.45 MPMX19_06850 putative tartrate dehydrogenase/decarboxylase TtuC' low > 112
Rhodopseudomonas palustris CGA009 0.17 TX73_005910 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.65 TX73_008960 tartrate dehydrogenase low > 86
Agrobacterium fabrum C58 0.17 Atu0657 hypothetical protein 0.46 Atu3402 3-isopropylmalate dehydrogenase low > 89
Bosea sp. OAE506 0.16 ABIE41_RS23100 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.66 ABIE41_RS22540 tartrate dehydrogenase low > 77
Sinorhizobium meliloti 1021 0.16 SMc00826 16S ribosomal RNA methyltransferase RsmE 0.45 SMa1846 3-isopropylmalate dehydrogenase low > 103
Magnetospirillum magneticum AMB-1 0.15 AMB_RS01240 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.49 AMB_RS16020 tartrate dehydrogenase — —
Mycobacterium tuberculosis H37Rv 0.15 Rv2372c Conserved hypothetical protein 0.31 Rv2995c Probable 3-isopropylmalate dehydrogenase LeuB (beta-IPM dehydrogenase) (IMDH) (3-IPM-DH) — —
Bifidobacterium breve UCC2003 0.11 BBR_RS15150 16S rRNA (uracil(1498)-N(3))-methyltransferase 0.36 BBR_RS12870 3-isopropylmalate dehydrogenase low > 34

Not shown: 41 genomes with orthologs for ECD_02776 only; 3 genomes with orthologs for ECD_01770 only