Conservation of cofitness between CSW01_11570 and CSW01_18965 in Vibrio cholerae E7946 ATCC 55056

81 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_11570 glutamate-5-semialdehyde dehydrogenase 1.0 CSW01_18965 DUF1255 domain-containing protein 0.42 7
Dickeya dadantii 3937 0.62 DDA3937_RS16530 glutamate-5-semialdehyde dehydrogenase 0.40 DDA3937_RS05395 pyrimidine/purine nucleoside phosphorylase low > 74
Dickeya dianthicola 67-19 0.62 HGI48_RS16600 glutamate-5-semialdehyde dehydrogenase 0.41 HGI48_RS05455 pyrimidine/purine nucleoside phosphorylase low > 71
Serratia liquefaciens MT49 0.61 IAI46_04435 glutamate-5-semialdehyde dehydrogenase 0.45 IAI46_04705 pyrimidine/purine nucleoside phosphorylase low > 87
Dickeya dianthicola ME23 0.61 DZA65_RS17690 glutamate-5-semialdehyde dehydrogenase 0.40 DZA65_RS05775 pyrimidine/purine nucleoside phosphorylase low > 75
Pectobacterium carotovorum WPP14 0.60 HER17_RS04705 glutamate-5-semialdehyde dehydrogenase 0.45 HER17_RS16090 pyrimidine/purine nucleoside phosphorylase low > 75
Rahnella sp. WP5 0.60 EX31_RS20975 glutamate-5-semialdehyde dehydrogenase 0.48 EX31_RS21985 pyrimidine/purine nucleoside phosphorylase low > 89
Klebsiella michiganensis M5al 0.60 BWI76_RS05835 gamma-glutamyl-phosphate reductase 0.49 BWI76_RS06200 hypothetical protein low > 92
Klebsiella pneumoniae MKP103 0.59 KDGMDA_14000 glutamate-5-semialdehyde dehydrogenase 0.49 KDGMDA_14280 pyrimidine/purine nucleoside phosphorylase low > 94
Klebsiella pneumoniae MRSN742743 0.59 GJGHJB_03991 proA glutamate-5-semialdehyde dehydrogenase 0.49 GJGHJB_03936 ppnP pyrimidine/purine nucleoside phosphorylase low > 83
Erwinia tracheiphila HP pepo 2.2 0.59 IJEDHG_15495 proA glutamate-5-semialdehyde dehydrogenase 0.44 IJEDHG_26165 ppnP pyrimidine/purine nucleoside phosphorylase low > 61
Erwinia tracheiphila SCR3 0.59 LU632_RS01190 proA glutamate-5-semialdehyde dehydrogenase 0.44 LU632_RS18960 ppnP pyrimidine/purine nucleoside phosphorylase low > 73
Erwinia amylovora T8 0.59 OLJFJH_18405 glutamate-5-semialdehyde dehydrogenase 0.43 OLJFJH_18240 pyrimidine/purine nucleoside phosphorylase low > 58
Escherichia coli Nissle 1917 0.58 ECOLIN_RS01830 glutamate-5-semialdehyde dehydrogenase 0.45 ECOLIN_RS02375 pyrimidine/purine nucleoside phosphorylase low > 55
Escherichia coli BL21 0.58 ECD_00240 gamma-glutamylphosphate reductase 0.45 ECD_00338 UPF0345 family protein low > 61
Escherichia coli ECRC99 0.58 KEDOAH_18485 proA glutamate-5-semialdehyde dehydrogenase 0.45 KEDOAH_19380 ppnP pyrimidine/purine nucleoside phosphorylase — —
Escherichia coli ECRC102 0.58 NIAGMN_07530 proA glutamate-5-semialdehyde dehydrogenase 0.45 NIAGMN_06640 ppnP pyrimidine/purine nucleoside phosphorylase low > 80
Escherichia coli ECRC101 0.58 MCAODC_00190 proA glutamate-5-semialdehyde dehydrogenase 0.45 MCAODC_27810 ppnP pyrimidine/purine nucleoside phosphorylase low > 87
Escherichia coli ECRC100 0.58 OKFHMN_09670 proA glutamate-5-semialdehyde dehydrogenase 0.45 OKFHMN_08585 ppnP pyrimidine/purine nucleoside phosphorylase low > 79
Escherichia coli ECRC98 0.58 JDDGAC_13295 proA glutamate-5-semialdehyde dehydrogenase 0.45 JDDGAC_12240 ppnP pyrimidine/purine nucleoside phosphorylase low > 87
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.58 GFF4115 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.47 GFF4289 Cytoplasmic protein YaiE low > 78
Enterobacter asburiae PDN3 0.58 EX28DRAFT_2650 glutamate-5-semialdehyde dehydrogenase (EC 1.2.1.41) 0.46 EX28DRAFT_2580 Uncharacterized protein conserved in bacteria low > 76
Escherichia coli ECOR38 0.58 HEPCGN_07775 proA glutamate-5-semialdehyde dehydrogenase 0.45 HEPCGN_07225 ppnP pyrimidine/purine nucleoside phosphorylase low > 88
Escherichia coli BW25113 0.58 b0243 proA gamma-glutamyl phosphate reductase (NCBI) 0.45 b0391 yaiE hypothetical protein (NCBI) low > 76
Enterobacter sp. TBS_079 0.58 MPMX20_00928 Gamma-glutamyl phosphate reductase 0.46 MPMX20_00981 Pyrimidine/purine nucleoside phosphorylase low > 85
Escherichia coli ECOR27 0.58 NOLOHH_02045 proA glutamate-5-semialdehyde dehydrogenase 0.45 NOLOHH_01510 ppnP pyrimidine/purine nucleoside phosphorylase low > 75
Escherichia coli ECRC62 0.58 BNILDI_00240 proA glutamate-5-semialdehyde dehydrogenase 0.45 BNILDI_22925 ppnP pyrimidine/purine nucleoside phosphorylase low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.58 OHPLBJKB_03397 Gamma-glutamyl phosphate reductase 0.45 OHPLBJKB_03283 Pyrimidine/purine nucleoside phosphorylase low > 74
Escherichia fergusonii Becca 0.57 EFB2_03777 Gamma-glutamyl phosphate reductase 0.45 EFB2_03665 Pyrimidine/purine nucleoside phosphorylase low > 86
Pantoea agglomerans CFBP13505 P0401 0.57 PagCFBP13516_RS15415 proA glutamate-5-semialdehyde dehydrogenase 0.45 PagCFBP13516_RS15195 ppnP pyrimidine/purine nucleoside phosphorylase — —
Pantoea sp. MT58 0.57 IAI47_15115 glutamate-5-semialdehyde dehydrogenase 0.45 IAI47_14920 pyrimidine/purine nucleoside phosphorylase low > 76
Shewanella sp. ANA-3 0.54 Shewana3_0955 proA gamma-glutamyl phosphate reductase (RefSeq) 0.31 Shewana3_0263 hypothetical protein (RefSeq) low > 73
Shewanella oneidensis MR-1 0.54 SO1122 proA gamma-glutamyl phosphate reductase (NCBI ptt file) 0.31 SO4467 conserved hypothetical protein (NCBI ptt file) low > 76
Shewanella amazonensis SB2B 0.51 Sama_2515 proA gamma-glutamyl phosphate reductase (RefSeq) 0.32 Sama_3424 hypothetical protein (RefSeq) low > 62
Pseudomonas stutzeri RCH2 0.42 Psest_0508 gamma-glutamyl phosphate reductase 0.45 Psest_2502 Uncharacterized protein conserved in bacteria low > 67
Pseudomonas sp. S08-1 0.41 OH686_09340 Gamma-glutamyl phosphate reductase 0.50 OH686_02025 Pyrimidine/purine nucleoside phosphorylase PpnP low > 80
Pseudomonas fluorescens SBW25 0.41 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase 0.48 PFLU_RS21575 pyrimidine/purine nucleoside phosphorylase — —
Pseudomonas fluorescens SBW25-INTG 0.41 PFLU_RS26675 glutamate-5-semialdehyde dehydrogenase 0.48 PFLU_RS21575 pyrimidine/purine nucleoside phosphorylase — —
Pseudomonas protegens RBAN4 0.41 FABNJH_27550 proA glutamate-5-semialdehyde dehydrogenase 0.50 FABNJH_21695 ppnP Pyrimidine/purine nucleoside phosphorylase — —
Pseudomonas orientalis W4I3 0.41 QF045_RS27030 glutamate-5-semialdehyde dehydrogenase 0.47 QF045_RS21750 pyrimidine/purine nucleoside phosphorylase — —
Pseudomonas simiae WCS417 0.41 PS417_24745 gamma-glutamyl phosphate reductase 0.49 PS417_19605 hypothetical protein low > 88
Pseudomonas lactucae CFBP13502 0.41 GEMAOFIL_05102 Gamma-glutamyl phosphate reductase 0.49 GEMAOFIL_04121 Pyrimidine/purine nucleoside phosphorylase — —
Paraburkholderia sabiae LMG 24235 0.40 QEN71_RS26940 glutamate-5-semialdehyde dehydrogenase 0.33 QEN71_RS33290 pyrimidine/purine nucleoside phosphorylase low > 153
Dechlorosoma suillum PS 0.40 Dsui_1220 gamma-glutamyl phosphate reductase 0.33 Dsui_3246 hypothetical protein — —
Pseudomonas aeruginosa MRSN321 0.40 PFGADD_00950 proA glutamate-5-semialdehyde dehydrogenase 0.43 PFGADD_03565 ppnP Pyrimidine/purine nucleoside phosphorylase low > 99
Pseudomonas aeruginosa PUPa3 0.40 NPBIFN_00955 proA glutamate-5-semialdehyde dehydrogenase 0.43 NPBIFN_03601 ppnP Pyrimidine/purine nucleoside phosphorylase low > 101
Pseudomonas aeruginosa PA14 0.40 IKLFDK_20665 glutamate-5-semialdehyde dehydrogenase 0.43 IKLFDK_07530 Pyrimidine/purine nucleoside phosphorylase — —
Marinobacter adhaerens HP15 0.40 HP15_601 gamma-glutamyl phosphate reductase 0.43 HP15_2594 hypothetical protein — —
Acinetobacter radioresistens SK82 0.39 MPMX26_00417 Gamma-glutamyl phosphate reductase 0.29 MPMX26_00240 Pyrimidine/purine nucleoside phosphorylase low > 36
Methylophilus sp. DMC18 0.39 GFF254 Gamma-glutamyl phosphate reductase 0.33 GFF649 Pyrimidine/purine nucleoside phosphorylase — —
Alteromonas macleodii MIT1002 0.39 MIT1002_01885 Gamma-glutamyl phosphate reductase 0.41 MIT1002_01116 hypothetical protein low > 70
Pseudomonas segetis P6 0.39 ACVTMO_RS05195 glutamate-5-semialdehyde dehydrogenase 0.44 ACVTMO_RS11620 ppnP pyrimidine/purine nucleoside phosphorylase — —
Pseudomonas syringae pv. syringae B728a 0.39 Psyr_4369 glutamate-5-semialdehyde dehydrogenase 0.49 Psyr_1831 Protein of unknown function DUF1255 — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.39 Psyr_4369 glutamate-5-semialdehyde dehydrogenase 0.49 Psyr_1831 Protein of unknown function DUF1255 — —
Pedobacter sp. GW460-11-11-14-LB5 0.39 CA265_RS20850 glutamate-5-semialdehyde dehydrogenase 0.47 CA265_RS10695 hypothetical protein low > 88
Pseudomonas putida KT2440 0.39 PP_4811 Gamma-glutamyl phosphate reductase 0.49 PP_4248 conserved protein of unknown function, UPF0345 family — —
Acinetobacter baumannii LAC-4 0.38 RR41_RS16505 glutamate-5-semialdehyde dehydrogenase 0.27 RR41_RS17370 pyrimidine/purine nucleoside phosphorylase low > 55
Ralstonia solanacearum GMI1000 0.38 RS_RS13715 gamma-glutamyl-phosphate reductase 0.32 RS_RS12795 hypothetical protein — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.38 ABZR88_RS22165 glutamate-5-semialdehyde dehydrogenase 0.40 ABZR88_RS07110 pyrimidine/purine nucleoside phosphorylase low > 71
Pseudomonas sp. RS175 0.38 PFR28_03872 Gamma-glutamyl phosphate reductase 0.50 PFR28_01014 Pyrimidine/purine nucleoside phosphorylase — —
Pseudomonas fluorescens FW300-N1B4 0.38 Pf1N1B4_2688 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.48 Pf1N1B4_227 FIG074102: hypothetical protein — —
Pseudomonas fluorescens FW300-N2E2 0.38 Pf6N2E2_4993 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.50 Pf6N2E2_2413 FIG074102: hypothetical protein low > 103
Burkholderia phytofirmans PsJN 0.38 BPHYT_RS16770 gamma-glutamyl phosphate reductase 0.34 BPHYT_RS33245 hypothetical protein — —
Pseudomonas sp. DMC3 0.38 GFF3876 Gamma-glutamyl phosphate reductase 0.50 GFF4565 Pyrimidine/purine nucleoside phosphorylase low > 89
Paraburkholderia bryophila 376MFSha3.1 0.38 H281DRAFT_06324 glutamate-5-semialdehyde dehydrogenase 0.34 H281DRAFT_05998 hypothetical protein low > 103
Pseudomonas sp. SVBP6 0.38 COO64_RS15630 glutamate-5-semialdehyde dehydrogenase 0.49 COO64_RS18720 pyrimidine/purine nucleoside phosphorylase low > 91
Herbaspirillum seropedicae SmR1 0.38 HSERO_RS02965 gamma-glutamyl phosphate reductase 0.35 HSERO_RS07175 hypothetical protein low > 78
Ralstonia sp. UNC404CL21Col 0.38 ABZR87_RS01395 glutamate-5-semialdehyde dehydrogenase 0.35 ABZR87_RS00830 pyrimidine/purine nucleoside phosphorylase low > 80
Ralstonia solanacearum IBSBF1503 0.38 RALBFv3_RS05825 glutamate-5-semialdehyde dehydrogenase 0.33 RALBFv3_RS05175 DUF1255 domain-containing protein low > 76
Ralstonia solanacearum UW163 0.38 UW163_RS07800 glutamate-5-semialdehyde dehydrogenase 0.33 UW163_RS08450 DUF1255 domain-containing protein — —
Pseudomonas fluorescens FW300-N2C3 0.37 AO356_15290 gamma-glutamyl phosphate reductase 0.50 AO356_02940 hypothetical protein low > 104
Variovorax sp. SCN45 0.37 GFF6326 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.31 GFF3095 FIG074102: hypothetical protein — —
Ralstonia solanacearum PSI07 0.37 RPSI07_RS11475 glutamate-5-semialdehyde dehydrogenase 0.33 RPSI07_RS12125 DUF1255 domain-containing protein low > 81
Pseudomonas fluorescens FW300-N2E3 0.37 AO353_06495 gamma-glutamyl phosphate reductase 0.50 AO353_19295 hypothetical protein low > 101
Paraburkholderia graminis OAS925 0.37 ABIE53_003523 glutamate-5-semialdehyde dehydrogenase 0.34 ABIE53_004878 uncharacterized protein YaiE (UPF0345 family) low > 113
Pseudomonas fluorescens GW456-L13 0.37 PfGW456L13_1356 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.50 PfGW456L13_2282 FIG074102: hypothetical protein — —
Pseudomonas sp. BP01 0.37 JOY50_RS17680 glutamate-5-semialdehyde dehydrogenase 0.50 JOY50_RS00045 pyrimidine/purine nucleoside phosphorylase low > 84
Variovorax sp. OAS795 0.36 ABID97_RS04600 glutamate-5-semialdehyde dehydrogenase 0.31 ABID97_RS21665 pyrimidine/purine nucleoside phosphorylase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.36 GFF2641 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.32 GFF295 FIG074102: hypothetical protein — —
Acidovorax sp. GW101-3H11 0.36 Ac3H11_704 Gamma-glutamyl phosphate reductase (EC 1.2.1.41) 0.37 Ac3H11_2615 FIG074102: hypothetical protein low > 79
Cupriavidus basilensis FW507-4G11 0.33 RR42_RS17530 gamma-glutamyl phosphate reductase 0.33 RR42_RS17165 hypothetical protein low > 128
Cellulophaga baltica 18 0.29 M666_RS02645 glutamate-5-semialdehyde dehydrogenase 0.41 M666_RS15485 pyrimidine/purine nucleoside phosphorylase low > 67

Not shown: 41 genomes with orthologs for CSW01_11570 only; 0 genomes with orthologs for CSW01_18965 only