| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_05695 | | class I SAM-dependent methyltransferase | 1.0 | CSW01_12595 | | 2-isopropylmalate synthase | 0.57 | 5 |
| Rahnella sp. WP5 | 0.49 | EX31_RS23975 | | class I SAM-dependent methyltransferase | 0.71 | EX31_RS03680 | | 2-isopropylmalate synthase | low | > 89 |
| Klebsiella pneumoniae MKP103 | 0.48 | KDGMDA_11800 | | SAM-dependent methyltransferase | 0.69 | KDGMDA_12910 | | 2-isopropylmalate synthase | low | > 95 |
| Enterobacter sp. TBS_079 | 0.48 | MPMX20_02177 | | Tuberculostearic acid methyltransferase UfaA1 | 0.69 | MPMX20_00769 | | 2-isopropylmalate synthase | low | > 85 |
| Pectobacterium carotovorum WPP14 | 0.48 | HER17_RS10550 | | cyclopropane-fatty-acyl-phospholipid synthase family protein | 0.73 | HER17_RS03085 | | 2-isopropylmalate synthase | low | > 75 |
| Enterobacter asburiae PDN3 | 0.48 | EX28DRAFT_1371 | | Cyclopropane fatty acid synthase and related methyltransferases | 0.69 | EX28DRAFT_3670 | | 2-isopropylmalate synthase (EC 2.3.3.13) | low | > 76 |
| Shewanella loihica PV-4 | 0.48 | Shew_1484 | | cyclopropane-fatty-acyl-phospholipid synthase (RefSeq) | 0.71 | Shew_3472 | | 2-isopropylmalate synthase (RefSeq) | low | > 60 |
| Alteromonas macleodii MIT1002 | 0.47 | MIT1002_02688 | | Cyclopropane-fatty-acyl-phospholipid synthase | 0.66 | MIT1002_00949 | | 2-isopropylmalate synthase | low | > 70 |
| Erwinia tracheiphila HP pepo 2.2 | 0.47 | IJEDHG_19825 | | SAM-dependent methyltransferase | 0.69 | IJEDHG_05995 | leuA | 2-isopropylmalate synthase | low | > 61 |
| Erwinia tracheiphila SCR3 | 0.47 | LU632_RS09360 | | cyclopropane-fatty-acyl-phospholipid synthase family protein | 0.69 | LU632_RS02880 | leuA | 2-isopropylmalate synthase | low | > 73 |
| Klebsiella michiganensis M5al | 0.46 | BWI76_RS12565 | | SAM-dependent methyltransferase | 0.70 | BWI76_RS04680 | | 2-isopropylmalate synthase | low | > 92 |
| Erwinia amylovora T8 | 0.46 | OLJFJH_16600 | | SAM-dependent methyltransferase | 0.67 | OLJFJH_01285 | | 2-isopropylmalate synthase | low | > 58 |
| Shewanella amazonensis SB2B | 0.46 | Sama_0816 | | cyclopropane-fatty-acyl-phospholipid synthase (RefSeq) | 0.71 | Sama_0335 | | 2-isopropylmalate synthase (RefSeq) | low | > 62 |
| Shewanella oneidensis MR-1 | 0.46 | SO3379 | cfa | cyclopropane-fatty-acyl-phospholipid synthase (NCBI ptt file) | 0.72 | SO4236 | leuA | 2-isopropylmalate synthase (NCBI ptt file) | 0.27 | 23 |
| Shewanella sp. ANA-3 | 0.45 | Shewana3_1171 | | cyclopropane-fatty-acyl-phospholipid synthase (RefSeq) | 0.72 | Shewana3_3761 | | 2-isopropylmalate synthase (RefSeq) | low | > 73 |
| Pseudomonas lactucae CFBP13502 | 0.44 | GEMAOFIL_00934 | | hypothetical protein | 0.11 | GEMAOFIL_04774 | | 2-isopropylmalate synthase | low | > 96 |
| Pseudomonas orientalis W4I3 | 0.44 | QF045_RS06620 | | cyclopropane-fatty-acyl-phospholipid synthase family protein | 0.11 | QF045_RS25330 | | 2-isopropylmalate synthase | low | > 93 |
| Pseudomonas simiae WCS417 | 0.44 | PS417_03640 | | cyclopropane-fatty-acyl-phospholipid synthase | 0.11 | PS417_23110 | | 2-isopropylmalate synthase | low | > 88 |
| Pseudomonas sp. DMC3 | 0.43 | GFF4484 | | Tuberculostearic acid methyltransferase UfaA1 | 0.11 | GFF4332 | | 2-isopropylmalate synthase | low | > 89 |
| Pseudomonas fluorescens SBW25-INTG | 0.43 | PFLU_RS03690 | | class I SAM-dependent methyltransferase | 0.11 | PFLU_RS24765 | | 2-isopropylmalate synthase | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.43 | PFLU_RS03690 | | class I SAM-dependent methyltransferase | 0.11 | PFLU_RS24765 | | 2-isopropylmalate synthase | low | > 109 |
| Pseudomonas sp. S08-1 | 0.43 | OH686_07875 | | S-adenosyl-L-methionine dependent methyltransferase, similar to cyclopropane-fatty-acyl-phospholipid synthase | 0.12 | OH686_17570 | | 2-isopropylmalate synthase | low | > 80 |
| Pseudomonas syringae pv. syringae B728a | 0.43 | Psyr_0956 | | Cyclopropane-fatty-acyl-phospholipid synthase | 0.11 | Psyr_1257 | | 2-isopropylmalate synthase | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.43 | Psyr_0956 | | Cyclopropane-fatty-acyl-phospholipid synthase | 0.11 | Psyr_1257 | | 2-isopropylmalate synthase | low | > 86 |
| Methylophilus sp. DMC18 | 0.42 | GFF716 | | Tuberculostearic acid methyltransferase UfaA1 | 0.44 | GFF1746 | | 2-isopropylmalate synthase | low | > 43 |
| Pseudomonas stutzeri RCH2 | 0.42 | Psest_2402 | | Cyclopropane fatty acid synthase and related methyltransferases | 0.48 | Psest_1056 | | 2-isopropylmalate synthase, bacterial type | low | > 67 |
| Pseudomonas segetis P6 | 0.42 | MPMX49_01343 | | Tuberculostearic acid methyltransferase UfaA1 | 0.13 | MPMX49_01526 | | 2-isopropylmalate synthase | low | > 75 |
| Pseudomonas fluorescens FW300-N2C3 | 0.42 | AO356_25315 | | cyclopropane-fatty-acyl-phospholipid synthase | 0.11 | AO356_06550 | | 2-isopropylmalate synthase | low | > 104 |
| Pseudomonas putida KT2440 | 0.42 | PP_2734 | | Cyclopropane-fatty-acyl-phospholipid synthase | 0.12 | PP_1025 | | 2-isopropylmalate synthase | low | > 96 |
| Pseudomonas sp. RS175 | 0.41 | PFR28_02038 | | hypothetical protein | 0.11 | PFR28_00305 | | 2-isopropylmalate synthase | low | > 88 |
| Pseudomonas fluorescens FW300-N2E2 | 0.41 | Pf6N2E2_1350 | | Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79), plant type | 0.11 | Pf6N2E2_3170 | | 2-isopropylmalate synthase (EC 2.3.3.13) | low | > 103 |
| Pseudomonas sp. BP01 | 0.41 | JOY50_RS03410 | | cyclopropane-fatty-acyl-phospholipid synthase family protein | 0.11 | JOY50_RS11470 | leuA | 2-isopropylmalate synthase | low | > 84 |
| Rhodanobacter denitrificans FW104-10B01 | 0.40 | LRK54_RS07535 | | cyclopropane-fatty-acyl-phospholipid synthase family protein | 0.40 | LRK54_RS10345 | | 2-isopropylmalate synthase | low | > 59 |
| Rhodanobacter denitrificans MT42 | 0.40 | LRK55_RS07275 | | cyclopropane-fatty-acyl-phospholipid synthase family protein | 0.40 | LRK55_RS09985 | | 2-isopropylmalate synthase | low | > 63 |
| Marinobacter adhaerens HP15 | 0.40 | HP15_1773 | | cyclopropane-fatty-acyl-phospholipid synthase | 0.46 | HP15_538 | | 2-isopropylmalate synthase | low | > 73 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.40 | Xcc-8004.3607.1 | | S-adenosyl-L-methionine dependent methyltransferase, similar to cyclopropane-fatty-acyl-phospholipid synthase | 0.40 | Xcc-8004.1056.1 | | 2-isopropylmalate synthase (EC 2.3.3.13) | low | > 74 |
| Rhodanobacter sp. FW510-T8 | 0.39 | OKGIIK_13955 | cfa | SAM-dependent methyltransferase | 0.39 | OKGIIK_13575 | leuA | 2-isopropylmalate synthase | low | > 53 |
| Lysobacter sp. OAE881 | 0.39 | ABIE51_RS02520 | | cyclopropane-fatty-acyl-phospholipid synthase family protein | 0.42 | ABIE51_RS17570 | | 2-isopropylmalate synthase | low | > 62 |
| Bosea sp. OAE506 | 0.36 | ABIE41_RS10305 | | cyclopropane-fatty-acyl-phospholipid synthase family protein | 0.45 | ABIE41_RS13000 | | 2-isopropylmalate synthase | low | > 77 |
| Rhizobium sp. OAE497 | 0.35 | ABIE40_RS08305 | | cyclopropane-fatty-acyl-phospholipid synthase family protein | 0.15 | ABIE40_RS06220 | | citramalate synthase | low | > 107 |
| Caulobacter crescentus NA1000 Δfur | 0.32 | CCNA_01494 | | cyclopropane-fatty-acyl-phospholipid synthase | 0.42 | CCNA_01610 | | 2-isopropylmalate synthase | low | > 67 |
| Caulobacter crescentus NA1000 | 0.32 | CCNA_01494 | | cyclopropane-fatty-acyl-phospholipid synthase | 0.42 | CCNA_01610 | | 2-isopropylmalate synthase | low | > 66 |
| Agrobacterium fabrum C58 | 0.32 | Atu1979 | | cyclopropane-fatty-acyl-phospholipid synthase | 0.11 | Atu2264 | | 2-isopropylmalate synthase | low | > 89 |
| Variovorax sp. OAS795 | 0.32 | ABID97_RS21850 | | cyclopropane-fatty-acyl-phospholipid synthase family protein | 0.41 | ABID97_RS14910 | | 2-isopropylmalate synthase | low | > 91 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.32 | GFF2526 | | S-adenosyl-L-methionine dependent methyltransferase, similar to cyclopropane-fatty-acyl-phospholipid synthase | 0.43 | GFF4281 | | 2-isopropylmalate synthase (EC 2.3.3.13) | low | > 90 |
| Phaeobacter inhibens DSM 17395 | 0.31 | PGA1_c13920 | | cyclopropane-fatty-acyl-phospholipid synthase Cfa | 0.41 | PGA1_c26470 | | 2-isopropylmalate synthase LeuA | low | > 62 |
| Acidovorax sp. GW101-3H11 | 0.30 | Ac3H11_1218 | | S-adenosyl-L-methionine dependent methyltransferase, similar to cyclopropane-fatty-acyl-phospholipid synthase | 0.42 | Ac3H11_530 | | 2-isopropylmalate synthase (EC 2.3.3.13) | low | > 79 |
| Variovorax sp. SCN45 | 0.30 | GFF5435 | | Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79), plant type | 0.41 | GFF1165 | | 2-isopropylmalate synthase (EC 2.3.3.13) | low | > 127 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.29 | H281DRAFT_01468 | | cyclopropane-fatty-acyl-phospholipid synthase | 0.42 | H281DRAFT_04556 | | 2-isopropylmalate synthase | low | > 103 |
| Cupriavidus basilensis FW507-4G11 | 0.29 | RR42_RS29215 | | cyclopropane-fatty-acyl-phospholipid synthase | 0.42 | RR42_RS05465 | | 2-isopropylmalate synthase | low | > 128 |
| Sphingomonas koreensis DSMZ 15582 | 0.28 | Ga0059261_0323 | | Cyclopropane fatty acid synthase and related methyltransferases | 0.11 | Ga0059261_4031 | | 2-isopropylmalate synthase, yeast type | low | > 68 |
| Burkholderia phytofirmans PsJN | 0.28 | BPHYT_RS05125 | | cyclopropane-fatty-acyl-phospholipid synthase | 0.42 | BPHYT_RS06570 | | 2-isopropylmalate synthase | low | > 109 |
| Ralstonia sp. UNC404CL21Col | 0.27 | ABZR87_RS21055 | | cyclopropane-fatty-acyl-phospholipid synthase family protein | 0.42 | ABZR87_RS14930 | | 2-isopropylmalate synthase | low | > 80 |
| Sphingobium sp. HT1-2 | 0.27 | GFF77 | | Cyclopropane-fatty-acyl-phospholipid synthase (EC 2.1.1.79), plant type | 0.10 | GFF2060 | | 2-isopropylmalate synthase (EC 2.3.3.13) | low | > 95 |
| Escherichia coli ECOR27 | 0.25 | NOLOHH_17890 | cfa | cyclopropane fatty acyl phospholipid synthase | 0.70 | NOLOHH_03060 | | 2-isopropylmalate synthase | — | — |
| Escherichia coli ECRC62 | 0.25 | BNILDI_16680 | cfa | cyclopropane fatty acyl phospholipid synthase | 0.70 | BNILDI_08550 | | 2-isopropylmalate synthase | low | > 75 |
| Escherichia coli ECRC101 | 0.25 | MCAODC_18040 | cfa | cyclopropane fatty acyl phospholipid synthase | 0.70 | MCAODC_01230 | | 2-isopropylmalate synthase | low | > 87 |
| Escherichia coli ECRC102 | 0.25 | NIAGMN_00695 | cfa | cyclopropane fatty acyl phospholipid synthase | 0.70 | NIAGMN_08565 | | 2-isopropylmalate synthase | low | > 80 |
| Escherichia coli ECRC98 | 0.25 | JDDGAC_01960 | cfa | cyclopropane fatty acyl phospholipid synthase | 0.70 | JDDGAC_14310 | | 2-isopropylmalate synthase | low | > 87 |
| Escherichia coli ECOR38 | 0.25 | HEPCGN_05755 | cfa | cyclopropane fatty acyl phospholipid synthase | 0.70 | HEPCGN_08695 | | 2-isopropylmalate synthase | low | > 88 |
| Escherichia coli BW25113 | 0.25 | b1661 | cfa | cyclopropane fatty acyl phospholipid synthase (unsaturated-phospholipid methyltransferase) (NCBI) | 0.70 | b0074 | leuA | 2-isopropylmalate synthase (NCBI) | 0.23 | 55 |
| Escherichia coli Nissle 1917 | 0.25 | ECOLIN_RS09260 | | cyclopropane fatty acyl phospholipid synthase | 0.70 | ECOLIN_RS00400 | | 2-isopropylmalate synthase | low | > 55 |
| Escherichia coli ECRC100 | 0.25 | OKFHMN_27370 | cfa | cyclopropane fatty acyl phospholipid synthase | 0.70 | OKFHMN_10715 | | 2-isopropylmalate synthase | low | > 79 |
| Escherichia coli BL21 | 0.25 | ECD_01632 | | cyclopropane fatty acyl phospholipid synthase, SAM-dependent | 0.70 | ECD_00076 | | 2-isopropylmalate synthase | 0.53 | 6 |
| Escherichia coli ECRC99 | 0.25 | KEDOAH_00740 | cfa | cyclopropane fatty acyl phospholipid synthase | 0.70 | KEDOAH_17440 | | 2-isopropylmalate synthase | — | — |
| Escherichia fergusonii Becca | 0.25 | EFB2_02331 | | Cyclopropane-fatty-acyl-phospholipid synthase | 0.70 | EFB2_03971 | | 2-isopropylmalate synthase | low | > 86 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.25 | OHPLBJKB_02063 | | Cyclopropane-fatty-acyl-phospholipid synthase | 0.70 | OHPLBJKB_03583 | | 2-isopropylmalate synthase | low | > 74 |
| Dickeya dianthicola ME23 | 0.24 | DZA65_RS13145 | | cyclopropane fatty acyl phospholipid synthase | 0.71 | DZA65_RS19200 | | 2-isopropylmalate synthase | low | > 75 |
| Serratia liquefaciens MT49 | 0.24 | IAI46_11225 | | cyclopropane fatty acyl phospholipid synthase | 0.74 | IAI46_03355 | | 2-isopropylmalate synthase | 0.51 | 47 |
| Dickeya dadantii 3937 | 0.24 | DDA3937_RS07210 | | cyclopropane fatty acyl phospholipid synthase | 0.71 | DDA3937_RS18115 | | 2-isopropylmalate synthase | low | > 74 |
| Dickeya dianthicola 67-19 | 0.24 | HGI48_RS12690 | | cyclopropane fatty acyl phospholipid synthase | 0.71 | HGI48_RS18055 | | 2-isopropylmalate synthase | low | > 71 |
| Pantoea sp. MT58 | 0.23 | IAI47_10810 | | cyclopropane fatty acyl phospholipid synthase | 0.68 | IAI47_16000 | | 2-isopropylmalate synthase | low | > 76 |
| Sinorhizobium meliloti 1021 | 0.23 | SMc00358 | | cyclopropane-fatty-acyl-phospholipid synthase | 0.15 | SMc02546 | | alpha-isopropylmalate/homocitrate synthase family transferase | low | > 103 |
| Pantoea agglomerans CFBP13505 P0401 | 0.23 | PagCFBP13505_RS17780 | | cyclopropane fatty acyl phospholipid synthase | 0.68 | PagCFBP13505_RS13000 | | 2-isopropylmalate synthase | low | > 74 |
Not shown: 9 genomes with orthologs for CSW01_05695 only; 29 genomes with orthologs for CSW01_12595 only