Conservation of cofitness between CSW01_12260 and CSW01_12405 in Vibrio cholerae E7946 ATCC 55056

74 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_12260 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 1.0 CSW01_12405 GTP diphosphokinase 0.67 3
Escherichia coli ECOR38 0.62 HEPCGN_08505 ampD 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 HEPCGN_19500 relA GTP diphosphokinase low > 88
Escherichia fergusonii Becca 0.62 EFB2_03939 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 EFB2_01133 GTP pyrophosphokinase low > 86
Escherichia coli Nissle 1917 0.62 ECOLIN_RS00590 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 ECOLIN_RS15515 GTP diphosphokinase low > 55
Enterobacter sp. TBS_079 0.62 MPMX20_00801 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.66 MPMX20_03653 GTP pyrophosphokinase low > 85
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.61 GFF129 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) AmpD 0.67 GFF4837 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 low > 78
Escherichia coli ECRC101 0.61 MCAODC_01040 ampD 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 MCAODC_10775 relA GTP diphosphokinase low > 87
Escherichia coli ECRC100 0.61 OKFHMN_10525 ampD 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 OKFHMN_20250 relA GTP diphosphokinase low > 79
Escherichia coli ECRC98 0.61 JDDGAC_14120 ampD 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 JDDGAC_23915 relA GTP diphosphokinase low > 87
Enterobacter asburiae PDN3 0.61 EX28DRAFT_3703 N-acetylmuramoyl-L-alanine amidase 0.66 EX28DRAFT_2864 (p)ppGpp synthetase, RelA/SpoT family
Escherichia coli ECRC99 0.61 KEDOAH_17630 ampD 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 KEDOAH_07880 relA GTP diphosphokinase
Erwinia amylovora T8 0.61 OLJFJH_01045 1 6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.66 OLJFJH_09245 GTP diphosphokinase low > 58
Escherichia coli ECRC102 0.61 NIAGMN_08375 ampD 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 NIAGMN_18020 relA GTP diphosphokinase low > 80
Escherichia coli HS(pFamp)R (ATCC 700891) 0.61 OHPLBJKB_03551 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 OHPLBJKB_00947 GTP pyrophosphokinase low > 74
Alteromonas macleodii MIT1002 0.61 MIT1002_03006 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.53 MIT1002_00794 GTP pyrophosphokinase low > 70
Escherichia coli BW25113 0.61 b0110 ampD N-acetyl-anhydromuranmyl-L-alanine amidase (NCBI) 0.67 b2784 relA (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) low > 76
Escherichia coli ECOR27 0.61 NOLOHH_02870 ampD 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 NOLOHH_12125 relA GTP diphosphokinase low > 76
Escherichia coli ECRC62 0.61 BNILDI_08740 ampD 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 BNILDI_10630 relA GTP diphosphokinase low > 75
Escherichia coli BL21 0.61 ECD_00109 1,6-anhydro-N-acetylmuramyl-L-alanine amidase, Zn-dependent; murein amidase 0.67 ECD_02629 (p)ppGpp synthetase I/GTP pyrophosphokinase low > 61
Klebsiella michiganensis M5al 0.61 BWI76_RS04850 N-acetylmuramoyl-L-alanine amidase 0.67 BWI76_RS22805 GTP diphosphokinase low > 92
Klebsiella pneumoniae MKP103 0.60 KDGMDA_13085 1 6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 KDGMDA_03335 GTP diphosphokinase 0.73 18
Kangiella aquimarina DSM 16071 0.60 B158DRAFT_2134 Negative regulator of beta-lactamase expression 0.43 B158DRAFT_2277 (p)ppGpp synthetase, RelA/SpoT family low > 40
Rahnella sp. WP5 0.59 EX31_RS03510 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.66 EX31_RS07955 GTP diphosphokinase 0.60 7
Herbaspirillum seropedicae SmR1 0.59 HSERO_RS01880 N-acetyl-anhydromuranmyl-L-alanine amidase 0.35 HSERO_RS09855 GTP pyrophosphokinase low > 78
Pantoea sp. MT58 0.58 IAI47_15840 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.66 IAI47_04120 GTP diphosphokinase low > 76
Pantoea agglomerans CFBP13505 P0401 0.58 PagCFBP13505_RS13160 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.66 PagCFBP13505_RS16850 GTP diphosphokinase low > 74
Serratia liquefaciens MT49 0.57 IAI46_03535 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.66 IAI46_03600 GTP diphosphokinase low > 87
Pseudomonas segetis P6 0.56 MPMX49_03899 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.44 MPMX49_01654 GTP pyrophosphokinase low > 75
Dickeya dianthicola ME23 0.56 DZA65_RS19020 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 DZA65_RS18145 GTP diphosphokinase 0.56 2
Dickeya dianthicola 67-19 0.56 HGI48_RS17875 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 HGI48_RS17070 GTP diphosphokinase low > 71
Pectobacterium carotovorum WPP14 0.56 HER17_RS03260 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.66 HER17_RS04115 GTP diphosphokinase low > 75
Dickeya dadantii 3937 0.56 DDA3937_RS17945 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.67 DDA3937_RS17015 GTP diphosphokinase low > 74
Pseudomonas sp. SVBP6 0.56 COO64_RS03530 ampD 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.45 COO64_RS07325 relA GTP diphosphokinase
Pseudomonas aeruginosa PA14 0.55 IKLFDK_01470 beta-lactamase expression regulator AmpD 0.45 IKLFDK_04200 GTP diphosphokinase low > 98
Pseudomonas aeruginosa PUPa3 0.55 DQ20_RS56325 ampD;go_function=N-acetylmuramoyl-L-alanine 1 6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.45 DQ20_RS45020 relA;go_process=guanosine GTP diphosphokinase low > 101
Shewanella sp. ANA-3 0.55 Shewana3_0423 N-acetyl-anhydromuranmyl-L-alanine amidase (RefSeq) 0.56 Shewana3_1111 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) low > 73
Pseudomonas lactucae CFBP13502 0.53 GEMAOFIL_00991 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.45 GEMAOFIL_04223 GTP pyrophosphokinase low > 96
Shewanella oneidensis MR-1 0.53 SO0421 ampD AmpD protein (NCBI ptt file) 0.56 SO3455 relA GTP pyrophosphokinase (NCBI ptt file) low > 76
Pseudomonas simiae WCS417 0.53 PS417_03935 N-acetyl-anhydromuranmyl-L-alanine amidase 0.45 PS417_20150 (p)ppGpp synthetase
Pseudomonas sp. RS175 0.53 PFR28_00100 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.45 PFR28_03223 GTP pyrophosphokinase low > 88
Marinobacter adhaerens HP15 0.53 HP15_1307 N-acetyl-anhydromuranmyl-L-alanine amidase 0.43 HP15_791 (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA
Pseudomonas fluorescens FW300-N1B4 0.53 Pf1N1B4_1151 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) AmpD 0.45 Pf1N1B4_3508 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Pseudomonas fluorescens SBW25-INTG 0.53 PFLU_RS03980 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.45 PFLU_RS22095 GTP diphosphokinase low > 109
Pseudomonas sp. S08-1 0.53 OH686_16530 1,6-anhydro-N-acetylmuramyl-L-alanine amidase 0.45 OH686_18960 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase , (p)ppGpp synthetase I low > 80
Pseudomonas fluorescens SBW25 0.53 PFLU_RS03980 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.45 PFLU_RS22095 GTP diphosphokinase 0.81 30
Shewanella amazonensis SB2B 0.53 Sama_0372 N-acetyl-anhydromuranmyl-L-alanine amidase (RefSeq) 0.57 Sama_1033 GTP diphosphokinase (RefSeq) low > 62
Pseudomonas sp. DMC3 0.53 GFF4998 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.45 GFF4818 GTP pyrophosphokinase low > 89
Shewanella loihica PV-4 0.53 Shew_3434 N-acetyl-anhydromuranmyl-L-alanine amidase (RefSeq) 0.56 Shew_1202 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) low > 60
Pseudomonas fluorescens GW456-L13 0.52 PfGW456L13_5081 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) AmpD 0.45 PfGW456L13_2035 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)
Pseudomonas stutzeri RCH2 0.52 Psest_0725 Negative regulator of beta-lactamase expression 0.44 Psest_1640 (p)ppGpp synthetase, RelA/SpoT family low > 67
Pseudomonas fluorescens FW300-N2C3 0.52 AO356_07360 N-acetyl-anhydromuranmyl-L-alanine amidase 0.45 AO356_19060 (p)ppGpp synthetase low > 104
Pseudomonas syringae pv. syringae B728a 0.52 Psyr_0817 N-acetylmuramoyl-L-alanine amidase, family 2 0.45 Psyr_3695 RelA/SpoT protein low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.52 Psyr_0817 N-acetylmuramoyl-L-alanine amidase, family 2 0.45 Psyr_3695 RelA/SpoT protein low > 86
Pseudomonas fluorescens FW300-N2E2 0.52 Pf6N2E2_3344 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) AmpD 0.45 Pf6N2E2_5723 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) low > 103
Pseudomonas fluorescens FW300-N2E3 0.51 AO353_05510 N-acetyl-anhydromuranmyl-L-alanine amidase 0.45 AO353_02710 (p)ppGpp synthetase low > 101
Pseudomonas putida KT2440 0.51 PP_0789 N-acetyl-anhydromuramyl-L-alanine-amidase 0.45 PP_1656 ATP:GTP 3'-pyrophosphotransferase low > 96
Pseudomonas sp. BP01 0.51 JOY50_RS19335 ampD 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.45 JOY50_RS23910 relA GTP diphosphokinase low > 84
Acinetobacter radioresistens SK82 0.50 MPMX26_00043 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.35 MPMX26_00539 GTP pyrophosphokinase low > 36
Castellaniella sp019104865 MT123 0.50 ABCV34_RS09025 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.34 ABCV34_RS08440 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 48
Acinetobacter baumannii LAC-4 0.49 RR41_RS18675 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.35 RR41_RS16080 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 55
Burkholderia phytofirmans PsJN 0.48 BPHYT_RS17065 N-acetyl-anhydromuranmyl-L-alanine amidase 0.35 BPHYT_RS13655 GTP pyrophosphokinase
Cupriavidus basilensis FW507-4G11 0.48 RR42_RS17865 N-acetyl-anhydromuranmyl-L-alanine amidase 0.37 RR42_RS06585 GTP pyrophosphokinase low > 128
Dechlorosoma suillum PS 0.47 Dsui_0134 negative regulator of beta-lactamase expression 0.38 Dsui_2816 (p)ppGpp synthetase, RelA/SpoT family low > 51
Paraburkholderia bryophila 376MFSha3.1 0.47 H281DRAFT_06273 AmpD protein 0.35 H281DRAFT_04499 GTP pyrophosphokinase low > 103
Paraburkholderia sabiae LMG 24235 0.47 QEN71_RS27225 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.37 QEN71_RS05265 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 153
Paraburkholderia graminis OAS925 0.47 ABIE53_003579 AmpD protein 0.35 ABIE53_002905 GTP pyrophosphokinase low > 113
Methylophilus sp. DMC18 0.47 GFF2302 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.37 GFF2658 GTP pyrophosphokinase
Hydrogenophaga sp. GW460-11-11-14-LB1 0.47 GFF594 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) AmpD 0.34 GFF4925 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I
Ralstonia solanacearum GMI1000 0.46 RS_RS14030 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.38 RS_RS07930 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Ralstonia solanacearum PSI07 0.45 RPSI07_RS11160 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.38 RPSI07_RS15685 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Ralstonia solanacearum UW163 0.45 UW163_RS07545 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.38 UW163_RS15115 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Ralstonia solanacearum IBSBF1503 0.45 RALBFv3_RS06080 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.38 RALBFv3_RS01805 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase
Variovorax sp. SCN45 0.45 GFF4433 1,6-anhydro-N-acetylmuramyl-L-alanine amidase 0.32 GFF403 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I low > 127
Ralstonia sp. UNC404CL21Col 0.44 ABZR87_RS01745 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD 0.38 ABZR87_RS13745 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase low > 80
Acidovorax sp. GW101-3H11 0.37 Ac3H11_4020 N-acetylmuramoyl-L-alanine amidase (EC 3.5.1.28) AmpD 0.34 Ac3H11_362 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I

Not shown: 1 genomes with orthologs for CSW01_12260 only; 16 genomes with orthologs for CSW01_12405 only