| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_06560 | | 6-carboxytetrahydropterin synthase QueD | 1.0 | CSW01_09870 | | pyridoxal phosphate-dependent aminotransferase | 0.58 | 4 |
| Erwinia amylovora T8 | 0.86 | OLJFJH_09295 | | 6-carboxytetrahydropterin synthase QueD | 0.80 | OLJFJH_11400 | | Glutamate-pyruvate aminotransferase AlaA | low | > 58 |
| Enterobacter sp. TBS_079 | 0.85 | MPMX20_03644 | | 6-carboxy-5,6,7,8-tetrahydropterin synthase | 0.81 | MPMX20_03220 | | Glutamate-pyruvate aminotransferase AlaA | low | > 85 |
| Klebsiella pneumoniae MKP103 | 0.85 | KDGMDA_03305 | | 6-carboxytetrahydropterin synthase QueD | 0.81 | KDGMDA_27080 | | alanine transaminase AlaA | low | > 95 |
| Escherichia coli ECOR38 | 0.85 | HEPCGN_19100 | queD | 6-carboxytetrahydropterin synthase QueD | 0.81 | HEPCGN_22030 | alaA | alanine transaminase AlaA | low | > 88 |
| Enterobacter asburiae PDN3 | 0.85 | EX28DRAFT_2854 | | queuosine biosynthesis protein QueD | 0.81 | EX28DRAFT_0319 | | Aspartate/tyrosine/aromatic aminotransferase | low | > 76 |
| Klebsiella michiganensis M5al | 0.85 | BWI76_RS22775 | | 6-carboxytetrahydropterin synthase QueD | 0.81 | BWI76_RS20205 | | aminotransferase AlaT | low | > 92 |
| Pantoea agglomerans CFBP13505 P0401 | 0.85 | PagCFBP13505_RS16820 | | 6-carboxytetrahydropterin synthase QueD | 0.80 | PagCFBP13505_RS00325 | | pyridoxal phosphate-dependent aminotransferase | low | > 74 |
| Pantoea sp. MT58 | 0.84 | IAI47_04145 | | 6-carboxytetrahydropterin synthase QueD | 0.80 | IAI47_06350 | | pyridoxal phosphate-dependent aminotransferase | low | > 76 |
| Dickeya dianthicola 67-19 | 0.84 | HGI48_RS17030 | | 6-carboxytetrahydropterin synthase QueD | 0.80 | HGI48_RS14320 | | pyridoxal phosphate-dependent aminotransferase | low | > 71 |
| Escherichia coli ECRC62 | 0.84 | BNILDI_10730 | queD | 6-carboxytetrahydropterin synthase QueD | 0.81 | BNILDI_13365 | alaA | alanine transaminase AlaA | 0.48 | 36 |
| Escherichia coli ECRC102 | 0.84 | NIAGMN_18135 | queD | 6-carboxytetrahydropterin synthase QueD | 0.81 | NIAGMN_20595 | alaA | alanine transaminase AlaA | low | > 80 |
| Escherichia coli ECRC101 | 0.84 | MCAODC_10890 | queD | 6-carboxytetrahydropterin synthase QueD | 0.81 | MCAODC_13865 | alaA | alanine transaminase AlaA | low | > 88 |
| Escherichia coli ECRC98 | 0.84 | JDDGAC_24030 | queD | 6-carboxytetrahydropterin synthase QueD | 0.81 | JDDGAC_26790 | alaA | alanine transaminase AlaA | low | > 87 |
| Escherichia coli ECOR27 | 0.84 | NOLOHH_12180 | queD | 6-carboxytetrahydropterin synthase QueD | 0.81 | NOLOHH_14445 | alaA | alanine transaminase AlaA | low | > 76 |
| Escherichia coli BW25113 | 0.84 | b2765 | ygcM | 6-pyruvoyl tetrahydrobiopterin synthase (PTPS) (NCBI) | 0.81 | b2290 | yfbQ | aspartate aminotransferase (NCBI) | low | > 76 |
| Escherichia coli BL21 | 0.84 | ECD_02610 | | 6-pyruvoyl tetrahydrobiopterin synthase (PTPS) | 0.81 | ECD_02215 | | glutamate-pyruvate aminotransferase; glutamic-pyruvic transaminase (GPT); alanine transaminase | low | > 61 |
| Escherichia fergusonii Becca | 0.84 | EFB2_01152 | | 6-carboxy-5,6,7,8-tetrahydropterin synthase | 0.81 | EFB2_01568 | | Glutamate-pyruvate aminotransferase AlaA | low | > 86 |
| Escherichia coli ECRC100 | 0.84 | OKFHMN_20365 | queD | 6-carboxytetrahydropterin synthase QueD | 0.81 | OKFHMN_22825 | alaA | alanine transaminase AlaA | 0.64 | 17 |
| Escherichia coli ECRC99 | 0.84 | KEDOAH_07760 | queD | 6-carboxytetrahydropterin synthase QueD | 0.81 | KEDOAH_05370 | alaA | alanine transaminase AlaA | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.84 | OHPLBJKB_00968 | | 6-carboxy-5,6,7,8-tetrahydropterin synthase | 0.81 | OHPLBJKB_01415 | | Glutamate-pyruvate aminotransferase AlaA | low | > 74 |
| Erwinia tracheiphila SCR3 | 0.83 | LU632_RS06395 | queD | 6-carboxytetrahydropterin synthase QueD | 0.80 | LU632_RS07955 | | pyridoxal phosphate-dependent aminotransferase | low | > 74 |
| Erwinia tracheiphila HP pepo 2.2 | 0.83 | IJEDHG_17415 | queD | 6-carboxytetrahydropterin synthase QueD | 0.80 | IJEDHG_18035 | aspB | aminotransferase | low | > 61 |
| Escherichia coli Nissle 1917 | 0.83 | ECOLIN_RS15415 | | 6-carboxytetrahydropterin synthase QueD | 0.81 | ECOLIN_RS13295 | | alanine transaminase AlaA | low | > 55 |
| Dickeya dianthicola ME23 | 0.83 | DZA65_RS18105 | | 6-carboxytetrahydropterin synthase QueD | 0.80 | DZA65_RS14995 | | pyridoxal phosphate-dependent aminotransferase | low | > 75 |
| Dickeya dadantii 3937 | 0.83 | DDA3937_RS16965 | | 6-carboxytetrahydropterin synthase QueD | 0.80 | DDA3937_RS14345 | | pyridoxal phosphate-dependent aminotransferase | low | > 74 |
| Rahnella sp. WP5 | 0.81 | EX31_RS07915 | | 6-carboxytetrahydropterin synthase QueD | 0.77 | EX31_RS19445 | | pyridoxal phosphate-dependent aminotransferase | low | > 89 |
| Pectobacterium carotovorum WPP14 | 0.80 | HER17_RS04205 | | 6-carboxytetrahydropterin synthase QueD | 0.78 | HER17_RS07115 | | pyridoxal phosphate-dependent aminotransferase | low | > 75 |
| Serratia liquefaciens MT49 | 0.79 | IAI46_03680 | | 6-carboxytetrahydropterin synthase QueD | 0.79 | IAI46_17720 | | pyridoxal phosphate-dependent aminotransferase | low | > 86 |
| Pseudomonas segetis P6 | 0.79 | MPMX49_02208 | | 6-carboxy-5,6,7,8-tetrahydropterin synthase | 0.73 | MPMX49_02271 | | Glutamate-pyruvate aminotransferase AlaA | low | > 75 |
| Pseudomonas aeruginosa PA14 | 0.76 | IKLFDK_13390 | | 6-carboxytetrahydropterin synthase QueD | 0.74 | IKLFDK_14365 | | aminotransferase | — | — |
| Pseudomonas sp. RS175 | 0.75 | PFR28_02851 | | 6-carboxy-5,6,7,8-tetrahydropterin synthase | 0.74 | PFR28_00984 | | Glutamate-pyruvate aminotransferase AlaA | low | > 88 |
| Pseudomonas simiae WCS417 | 0.75 | PS417_09830 | | 6-carboxy-5,6,7,8-tetrahydropterin synthase | 0.73 | PS417_08560 | | aminotransferase | low | > 88 |
| Pseudomonas lactucae CFBP13502 | 0.75 | GEMAOFIL_02161 | | 6-carboxy-5,6,7,8-tetrahydropterin synthase | 0.73 | GEMAOFIL_01844 | | Glutamate-pyruvate aminotransferase AlaA | low | > 93 |
| Pseudomonas fluorescens SBW25 | 0.75 | PFLU_RS10415 | | 6-carboxytetrahydropterin synthase QueD | 0.73 | PFLU_RS08510 | | pyridoxal phosphate-dependent aminotransferase | low | > 109 |
| Pseudomonas fluorescens FW300-N1B4 | 0.75 | Pf1N1B4_110 | | Queuosine biosynthesis QueD, PTPS-I | 0.73 | Pf1N1B4_261 | | Aspartate aminotransferase (EC 2.6.1.1) | low | > 87 |
| Pseudomonas fluorescens SBW25-INTG | 0.75 | PFLU_RS10415 | | 6-carboxytetrahydropterin synthase QueD | 0.73 | PFLU_RS08510 | | pyridoxal phosphate-dependent aminotransferase | low | > 109 |
| Lysobacter sp. OAE881 | 0.75 | ABIE51_RS17950 | | 6-carboxytetrahydropterin synthase QueD | 0.42 | ABIE51_RS18840 | | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | low | > 62 |
| Pseudomonas fluorescens FW300-N2E2 | 0.74 | Pf6N2E2_37 | | 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I | 0.73 | Pf6N2E2_2446 | | Aspartate aminotransferase (EC 2.6.1.1) | low | > 103 |
| Pseudomonas fluorescens FW300-N2C3 | 0.74 | AO356_21260 | | 6-carboxy-5,6,7,8-tetrahydropterin synthase | 0.73 | AO356_03090 | | aminotransferase | low | > 104 |
| Pseudomonas fluorescens GW456-L13 | 0.74 | PfGW456L13_2447 | | 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I | 0.73 | PfGW456L13_2252 | | Aspartate aminotransferase (EC 2.6.1.1) | low | > 87 |
| Pseudomonas sp. DMC3 | 0.74 | GFF1361 | | 6-carboxy-5,6,7,8-tetrahydropterin synthase | 0.73 | GFF4596 | | Glutamate-pyruvate aminotransferase AlaA | low | > 89 |
| Pseudomonas fluorescens FW300-N2E3 | 0.74 | AO353_19760 | | 6-carboxy-5,6,7,8-tetrahydropterin synthase | 0.73 | AO353_19150 | | aminotransferase | low | > 101 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.73 | Psyr_3215 | | 6-pyruvoyl tetrahydropterin synthase and hypothetical protein | 0.73 | Psyr_3615 | | Aminotransferase, class I and II | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.73 | Psyr_3215 | | 6-pyruvoyl tetrahydropterin synthase and hypothetical protein | 0.73 | Psyr_3615 | | Aminotransferase, class I and II | — | — |
| Pseudomonas putida KT2440 | 0.73 | PP_2341 | | 6-carboxy-5,6,7,8-tetrahydropterin synthase | 0.73 | PP_1872 | | glutamate-pyruvate aminotransferase | low | > 96 |
| Pseudomonas sp. BP01 | 0.73 | JOY50_RS10905 | queD | 6-carboxytetrahydropterin synthase QueD | 0.74 | JOY50_RS16985 | | pyridoxal phosphate-dependent aminotransferase | low | > 84 |
| Pseudomonas stutzeri RCH2 | 0.72 | Psest_2010 | | queuosine biosynthesis protein QueD | 0.74 | Psest_1772 | | Aspartate/tyrosine/aromatic aminotransferase | — | — |
| Pseudomonas sp. SVBP6 | 0.72 | COO64_RS17240 | queD | 6-carboxytetrahydropterin synthase QueD | 0.74 | COO64_RS05980 | | pyridoxal phosphate-dependent aminotransferase | low | > 93 |
| Pseudomonas sp. S08-1 | 0.71 | OH686_00030 | | queuosine biosynthesis protein QueD | 0.72 | OH686_22575 | | Alanine transaminase | 0.47 | 9 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.70 | Xcc-8004.4528.1 | | hypothetical protein | 0.39 | Xcc-8004.1010.1 | | Aspartate aminotransferase (EC 2.6.1.1) | low | > 74 |
| Rhodanobacter denitrificans MT42 | 0.66 | LRK55_RS09085 | | 6-carboxytetrahydropterin synthase QueD | 0.38 | LRK55_RS10860 | | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | low | > 63 |
| Rhodanobacter sp. FW510-T8 | 0.64 | OKGIIK_15925 | queD | 6-carboxytetrahydropterin synthase QueD | 0.38 | OKGIIK_12720 | aspB | aminotransferase | low | > 53 |
| Rhodanobacter denitrificans FW104-10B01 | 0.64 | LRK54_RS09655 | | 6-carboxytetrahydropterin synthase QueD | 0.38 | LRK54_RS11155 | | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | low | > 59 |
| Rhodanobacter sp000427505 FW510-R12 | 0.64 | LRK53_RS02150 | | 6-carboxytetrahydropterin synthase QueD | 0.39 | LRK53_RS04055 | | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | low | > 59 |
| Dyella japonica UNC79MFTsu3.2 | 0.64 | ABZR86_RS13650 | | 6-carboxytetrahydropterin synthase QueD | 0.38 | ABZR86_RS12435 | | aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme | low | > 74 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.59 | DVU2657 | | 6-pyruvoyl tetrahydrobiopterin synthase, putative (TIGR) | 0.16 | DVU3223 | aspB | aspartate aminotransferase (TIGR) | low | > 55 |
| Desulfovibrio vulgaris Miyazaki F | 0.57 | DvMF_1123 | | queuosine biosynthesis protein QueD (RefSeq) | 0.17 | DvMF_2204 | | aminotransferase class I and II (RefSeq) | — | — |
| Xanthobacter sp. DMC5 | 0.53 | GFF3475 | | hypothetical protein | 0.17 | GFF4663 | | Aspartate/prephenate aminotransferase | — | — |
| Rhodopseudomonas palustris CGA009 | 0.52 | TX73_008525 | | 6-carboxytetrahydropterin synthase QueD | 0.19 | TX73_022440 | | pyridoxal phosphate-dependent aminotransferase | — | — |
| Synechocystis sp000284455 PCC 6803 | 0.42 | SGL_RS15290 | | 6-carboxytetrahydropterin synthase QueD | 0.17 | SGL_RS13785 | | pyridoxal phosphate-dependent aminotransferase | — | — |
| Agrobacterium fabrum C58 | 0.34 | Atu3345 | | 6-pyruvoyl tetrahydrobiopterin synthase | 0.18 | Atu2196 | | aspartate aminotransferase A | — | — |
| Brevundimonas sp. GW460-12-10-14-LB2 | 0.33 | A4249_RS08690 | | 6-carboxytetrahydropterin synthase | 0.19 | A4249_RS04680 | | pyridoxal phosphate-dependent aminotransferase | — | — |
| Caulobacter crescentus NA1000 Δfur | 0.32 | CCNA_03260 | | queuosine biosynthesis protein QueD | 0.18 | CCNA_01603 | | aspartate aminotransferase | low | > 67 |
| Caulobacter crescentus NA1000 | 0.32 | CCNA_03260 | | queuosine biosynthesis protein QueD | 0.18 | CCNA_01603 | | aspartate aminotransferase | low | > 66 |
| Sinorhizobium meliloti 1021 | 0.32 | SM_b20939 | | 6-pyruvoyl-tetrahydropterin synthase | 0.18 | SMc01578 | | aspartate aminotransferase | low | > 103 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.28 | GFF4632 | | 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I | 0.68 | GFF3934 | | Aspartate aminotransferase (EC 2.6.1.1) | — | — |
| Variovorax sp. OAS795 | 0.28 | ABID97_RS07420 | | 6-carboxytetrahydropterin synthase | 0.67 | ABID97_RS10885 | | pyridoxal phosphate-dependent aminotransferase | low | > 91 |
| Phaeobacter inhibens DSM 17395 | 0.27 | PGA1_c05610 | | putative queuosine biosynthesis protein QueD | 0.16 | PGA1_c21250 | | aspartate aminotransferase AatA | low | > 62 |
| Methylophilus sp. DMC18 | 0.27 | GFF1366 | | hypothetical protein | 0.67 | GFF1162 | | Glutamate-pyruvate aminotransferase AlaA | — | — |
| Phocaeicola dorei CL03T12C01 | 0.27 | ABI39_RS10595 | | 6-carboxytetrahydropterin synthase QueD | 0.16 | ABI39_RS00770 | | pyridoxal phosphate-dependent aminotransferase | low | > 72 |
| Acidovorax sp. GW101-3H11 | 0.27 | Ac3H11_3826 | | 6-carboxytetrahydropterin synthase (EC 4.1.2.50) @ Queuosine biosynthesis QueD, PTPS-I | 0.68 | Ac3H11_1508 | | Aspartate aminotransferase (EC 2.6.1.1) | 0.43 | 62 |
| Variovorax sp. SCN45 | 0.27 | GFF2576 | | 6-carboxy-5,6,7,8-tetrahydropterin synthase (EC 4.1.2.50) | 0.67 | GFF2803 | | Alanine transaminase (EC 2.6.1.2) | low | > 127 |
| Phocaeicola vulgatus CL09T03C04 | 0.26 | HMPREF1058_RS14875 | | 6-carboxytetrahydropterin synthase QueD | 0.16 | HMPREF1058_RS06225 | | pyridoxal phosphate-dependent aminotransferase | low | > 67 |
| Bacteroides stercoris CC31F | 0.25 | HMPREF1181_RS13890 | | 6-carboxytetrahydropterin synthase QueD | 0.17 | HMPREF1181_RS03765 | | pyridoxal phosphate-dependent aminotransferase | low | > 56 |
| Parabacteroides merdae CL09T00C40 | 0.24 | HMPREF1078_RS00755 | | 6-carboxytetrahydropterin synthase QueD | 0.16 | HMPREF1078_RS13530 | | pyridoxal phosphate-dependent aminotransferase | — | — |
Not shown: 0 genomes with orthologs for CSW01_06560 only; 43 genomes with orthologs for CSW01_09870 only