Conservation of cofitness between CSW01_18005 and CSW01_09720 in Vibrio cholerae E7946 ATCC 55056

72 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_18005 low-specificity L-threonine aldolase 1.0 CSW01_09720 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD 0.41 20
Marinobacter adhaerens HP15 0.65 HP15_2794 L-allo-threonine aldolase 0.61 HP15_2187 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
Shewanella sp. ANA-3 0.65 Shewana3_1208 L-threonine aldolase (RefSeq) 0.68 Shewana3_2663 methenyltetrahydrofolate cyclohydrolase (RefSeq)
Shewanella oneidensis MR-1 0.64 SO3338 ybjU L-allo-threonine aldolase (NCBI ptt file) 0.66 SO1792 folD methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase (NCBI ptt file)
Shewanella amazonensis SB2B 0.62 Sama_2462 threonine aldolase (RefSeq) 0.68 Sama_1222 methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq)
Shewanella loihica PV-4 0.62 Shew_1155 threonine aldolase (RefSeq) 0.67 Shew_2510 methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq)
Pseudomonas fluorescens FW300-N2E2 0.58 Pf6N2E2_5674 Low-specificity L-threonine aldolase (EC 4.1.2.48) 0.61 Pf6N2E2_2221 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
Pseudomonas sp. RS175 0.58 PFR28_03275 Low specificity L-threonine aldolase 0.61 PFR28_01223 Bifunctional protein FolD protein
Pseudomonas fluorescens FW300-N2E3 0.57 AO353_02985 threonine aldolase 0.61 AO353_20145 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase
Pseudomonas fluorescens GW456-L13 0.57 PfGW456L13_1979 Low-specificity L-threonine aldolase (EC 4.1.2.48) 0.62 PfGW456L13_2550 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
Pseudomonas fluorescens FW300-N2C3 0.57 AO356_18765 threonine aldolase 0.61 AO356_01775 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase
Serratia liquefaciens MT49 0.57 IAI46_08460 low-specificity L-threonine aldolase 0.68 IAI46_05400 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Pseudomonas fluorescens FW300-N1B4 0.57 Pf1N1B4_3449 Low-specificity L-threonine aldolase (EC 4.1.2.48) 0.61 Pf1N1B4_3943 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
Pseudomonas protegens RBAN4 0.56 FABNJH_23280 ltaE low-specificity L-threonine aldolase 0.61 FABNJH_20635 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Pseudomonas orientalis W4I3 0.56 QF045_RS23775 low-specificity L-threonine aldolase 0.62 QF045_RS18930 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Pseudomonas syringae pv. syringae B728a 0.55 Psyr_3557 L-threonine aldolase 0.60 Psyr_1743 methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+)
Pseudomonas syringae pv. syringae B728a ΔmexB 0.55 Psyr_3557 L-threonine aldolase 0.60 Psyr_1743 methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+)
Pseudomonas simiae WCS417 0.55 PS417_21665 threonine aldolase 0.62 PS417_17265 methenyltetrahydrofolate cyclohydrolase
Pseudomonas fluorescens SBW25 0.54 PFLU_RS23275 low-specificity L-threonine aldolase 0.61 PFLU_RS19200 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Pseudomonas fluorescens SBW25-INTG 0.54 PFLU_RS23275 low-specificity L-threonine aldolase 0.61 PFLU_RS19200 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.54 GFF4912 Low-specificity L-threonine aldolase (EC 4.1.2.5) 0.68 GFF4447 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
Pseudomonas segetis P6 0.54 ACVTMO_RS15855 ltaE low-specificity L-threonine aldolase 0.60 ACVTMO_RS11215 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Pseudomonas sp. DMC3 0.54 GFF4871 Low specificity L-threonine aldolase 0.61 GFF1441 Bifunctional protein FolD protein
Klebsiella michiganensis M5al 0.54 BWI76_RS09550 low-specificity L-threonine aldolase 0.68 BWI76_RS07100 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase
Klebsiella pneumoniae MKP103 0.53 KDGMDA_17800 low-specificity L-threonine aldolase 0.68 KDGMDA_15035 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Pseudomonas lactucae CFBP13502 0.53 GEMAOFIL_04477 Low specificity L-threonine aldolase 0.61 GEMAOFIL_03749 Bifunctional protein FolD protein
Escherichia coli ECRC62 0.53 BNILDI_20500 ltaE low-specificity L-threonine aldolase 0.67 BNILDI_22225 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Escherichia coli HS(pFamp)R (ATCC 700891) 0.53 OHPLBJKB_02798 Low specificity L-threonine aldolase 0.68 OHPLBJKB_03152 Bifunctional protein FolD protein
Escherichia fergusonii Becca 0.53 EFB2_03191 Low specificity L-threonine aldolase 0.68 EFB2_03532 Bifunctional protein FolD protein
Escherichia coli ECOR27 0.53 NOLOHH_22245 ltaE low-specificity L-threonine aldolase 0.68 NOLOHH_00795 Bifunctional protein FolD
Rahnella sp. WP5 0.53 EX31_RS18605 low-specificity L-threonine aldolase 0.69 EX31_RS22835 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Escherichia coli BL21 0.53 ECD_00875 L-allo-threonine aldolase, PLP-dependent 0.68 ECD_00479 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase
Escherichia coli BW25113 0.53 b0870 ltaE L-allo-threonine aldolase, PLP-dependent (NCBI) 0.68 b0529 folD bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase (NCBI)
Enterobacter asburiae PDN3 0.53 EX28DRAFT_2063 L-threonine aldolase (EC 4.1.2.5) 0.68 EX28DRAFT_2449 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
Escherichia coli ECRC99 0.53 KEDOAH_22060 ltaE low-specificity L-threonine aldolase 0.68 KEDOAH_20165 Bifunctional protein FolD
Klebsiella pneumoniae MRSN742743 0.53 KFA93_RS01085 ltaE;go_function=lyase low-specificity L-threonine aldolase 0.68 KFA93_RS03235 folD;go_function=methylenetetrahydrofolate bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Escherichia coli ECRC98 0.53 JDDGAC_09485 ltaE low-specificity L-threonine aldolase 0.68 JDDGAC_11455 Bifunctional protein FolD
Escherichia coli ECRC101 0.53 MCAODC_25065 ltaE low-specificity L-threonine aldolase 0.68 MCAODC_27025 Bifunctional protein FolD
Escherichia coli ECRC100 0.53 OKFHMN_05850 ltaE low-specificity L-threonine aldolase 0.68 OKFHMN_07805 Bifunctional protein FolD
Escherichia coli ECOR38 0.53 HEPCGN_02165 ltaE low-specificity L-threonine aldolase 0.67 HEPCGN_06445 Bifunctional protein FolD
Escherichia coli ECRC102 0.53 NIAGMN_03890 ltaE low-specificity L-threonine aldolase 0.68 NIAGMN_05860 Bifunctional protein FolD
Escherichia coli Nissle 1917 0.53 ECOLIN_RS04630 low-specificity L-threonine aldolase 0.68 ECOLIN_RS03065 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Pseudomonas stutzeri RCH2 0.53 Psest_2990 Threonine aldolase 0.58 Psest_2301 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
Enterobacter sp. TBS_079 0.53 MPMX20_01531 Low specificity L-threonine aldolase 0.68 MPMX20_01107 Bifunctional protein FolD protein
Paraburkholderia graminis OAS925 0.52 ABIE53_005128 threonine aldolase 0.42 ABIE53_002796 methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase
Kangiella aquimarina DSM 16071 0.52 B158DRAFT_1832 L-threonine aldolase (EC 4.1.2.5) 0.57 B158DRAFT_1028 methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)/5,10-methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5)
Pseudomonas aeruginosa PA14 0.52 IKLFDK_04020 low-specificity L-threonine aldolase 0.62 IKLFDK_08690 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Pseudomonas aeruginosa MRSN321 0.52 DY961_RS07960 ltaE;go_function=lyase low-specificity L-threonine aldolase 0.62 DY961_RS20675 folD;go_function=methylenetetrahydrofolate bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Pseudomonas aeruginosa PUPa3 0.52 DQ20_RS44840 ltaE;go_function=lyase low-specificity L-threonine aldolase 0.62 DQ20_RS54755 folD;go_function=methylenetetrahydrofolate bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Lysobacter sp. OAE881 0.52 ABIE51_RS01760 low-specificity L-threonine aldolase 0.52 ABIE51_RS09470 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Erwinia amylovora T8 0.51 OLJFJH_16245 low-specificity L-threonine aldolase 0.67 OLJFJH_17600 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Paraburkholderia bryophila 376MFSha3.1 0.51 H281DRAFT_03052 L-threonine aldolase 0.42 H281DRAFT_00463 methenyltetrahydrofolate cyclohydrolase /5,10-methylenetetrahydrofolate dehydrogenase (NADP+)
Pantoea sp. MT58 0.51 IAI47_12975 low-specificity L-threonine aldolase 0.68 IAI47_14320 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Pantoea agglomerans CFBP13505 P0401 0.51 PagCFBP13516_RS13060 ltaE low-specificity L-threonine aldolase 0.68 PagCFBP13516_RS14565 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Variovorax sp. OAS795 0.50 ABID97_RS05265 low-specificity L-threonine aldolase 0.44 ABID97_RS14085 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Rhodanobacter denitrificans FW104-10B01 0.50 LRK54_RS12390 low-specificity L-threonine aldolase 0.55 LRK54_RS00100 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Rhodanobacter denitrificans MT42 0.50 LRK55_RS12125 low-specificity L-threonine aldolase 0.55 LRK55_RS18095 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Rhodanobacter sp000427505 FW510-R12 0.50 LRK53_RS16110 low-specificity L-threonine aldolase 0.56 LRK53_RS11165 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Burkholderia phytofirmans PsJN 0.50 BPHYT_RS29600 threonine aldolase 0.42 BPHYT_RS12865 bifunctional protein FolD
Dyella japonica UNC79MFTsu3.2 0.49 ABZR86_RS19205 low-specificity L-threonine aldolase 0.54 ABZR86_RS05415 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Paraburkholderia sabiae LMG 24235 0.49 QEN71_RS14320 low-specificity L-threonine aldolase 0.43 QEN71_RS05700 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Variovorax sp. SCN45 0.49 GFF5893 Low-specificity L-threonine aldolase (EC 4.1.2.48) 0.44 GFF964 Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) / Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5)
Rhodanobacter sp. FW510-T8 0.48 OKGIIK_11545 ltaE low-specificity L-threonine aldolase 0.54 OKGIIK_07100 folD bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Acidovorax sp. GW101-3H11 0.47 Ac3H11_4475 Low-specificity L-threonine aldolase (EC 4.1.2.48) 0.45 Ac3H11_4096 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
Hydrogenophaga sp. GW460-11-11-14-LB1 0.45 GFF3108 Low-specificity L-threonine aldolase (EC 4.1.2.48) 0.45 GFF4894 Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)
Ralstonia sp. UNC404CL21Col 0.45 ABZR87_RS05825 low-specificity L-threonine aldolase 0.45 ABZR87_RS13485 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD
Pontibacter actiniarum KMM 6156, DSM 19842 0.36 CA264_06480 threonine aldolase 0.43 CA264_07145 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase
Dinoroseobacter shibae DFL-12 0.36 Dshi_2144 Threonine aldolase (RefSeq) 0.37 Dshi_1285 Methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq)
Pedobacter sp. GW460-11-11-14-LB5 0.35 CA265_RS02210 threonine aldolase 0.38 CA265_RS08950 bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase
Mucilaginibacter yixingensis YX-36 DSM 26809 0.34 ABZR88_RS09335 low specificity L-threonine aldolase 0.39 ABZR88_RS09400 bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase
Echinicola vietnamensis KMM 6221, DSM 17526 0.32 Echvi_4604 Threonine aldolase 0.43 Echvi_4643 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase
Cellulophaga baltica 18 0.31 M666_RS13845 GntG family PLP-dependent aldolase 0.41 M666_RS00795 bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase
Rhodopseudomonas palustris CGA009 0.30 TX73_008155 threonine aldolase family protein 0.39 TX73_002145 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD

Not shown: 0 genomes with orthologs for CSW01_18005 only; 50 genomes with orthologs for CSW01_09720 only