| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_18005 | | low-specificity L-threonine aldolase | 1.0 | CSW01_09720 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | 0.41 | 20 |
| Marinobacter adhaerens HP15 | 0.65 | HP15_2794 | | L-allo-threonine aldolase | 0.61 | HP15_2187 | | methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase | — | — |
| Shewanella sp. ANA-3 | 0.65 | Shewana3_1208 | | L-threonine aldolase (RefSeq) | 0.68 | Shewana3_2663 | | methenyltetrahydrofolate cyclohydrolase (RefSeq) | — | — |
| Shewanella oneidensis MR-1 | 0.64 | SO3338 | ybjU | L-allo-threonine aldolase (NCBI ptt file) | 0.66 | SO1792 | folD | methylenetetrahydrofolate dehydrogenase/methylenetetrahydrofolate cyclohydrolase (NCBI ptt file) | — | — |
| Shewanella amazonensis SB2B | 0.62 | Sama_2462 | | threonine aldolase (RefSeq) | 0.68 | Sama_1222 | | methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq) | — | — |
| Shewanella loihica PV-4 | 0.62 | Shew_1155 | | threonine aldolase (RefSeq) | 0.67 | Shew_2510 | | methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq) | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.58 | Pf6N2E2_5674 | | Low-specificity L-threonine aldolase (EC 4.1.2.48) | 0.61 | Pf6N2E2_2221 | | Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | — | — |
| Pseudomonas sp. RS175 | 0.58 | PFR28_03275 | | Low specificity L-threonine aldolase | 0.61 | PFR28_01223 | | Bifunctional protein FolD protein | — | — |
| Pseudomonas fluorescens FW300-N2E3 | 0.57 | AO353_02985 | | threonine aldolase | 0.61 | AO353_20145 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.57 | PfGW456L13_1979 | | Low-specificity L-threonine aldolase (EC 4.1.2.48) | 0.62 | PfGW456L13_2550 | | Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.57 | AO356_18765 | | threonine aldolase | 0.61 | AO356_01775 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase | — | — |
| Serratia liquefaciens MT49 | 0.57 | IAI46_08460 | | low-specificity L-threonine aldolase | 0.68 | IAI46_05400 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.57 | Pf1N1B4_3449 | | Low-specificity L-threonine aldolase (EC 4.1.2.48) | 0.61 | Pf1N1B4_3943 | | Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | — | — |
| Pseudomonas protegens RBAN4 | 0.56 | FABNJH_23280 | ltaE | low-specificity L-threonine aldolase | 0.61 | FABNJH_20635 | folD | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Pseudomonas orientalis W4I3 | 0.56 | QF045_RS23775 | | low-specificity L-threonine aldolase | 0.62 | QF045_RS18930 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Pseudomonas syringae pv. syringae B728a | 0.55 | Psyr_3557 | | L-threonine aldolase | 0.60 | Psyr_1743 | | methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+) | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.55 | Psyr_3557 | | L-threonine aldolase | 0.60 | Psyr_1743 | | methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+) | — | — |
| Pseudomonas simiae WCS417 | 0.55 | PS417_21665 | | threonine aldolase | 0.62 | PS417_17265 | | methenyltetrahydrofolate cyclohydrolase | — | — |
| Pseudomonas fluorescens SBW25 | 0.54 | PFLU_RS23275 | | low-specificity L-threonine aldolase | 0.61 | PFLU_RS19200 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.54 | PFLU_RS23275 | | low-specificity L-threonine aldolase | 0.61 | PFLU_RS19200 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.54 | GFF4912 | | Low-specificity L-threonine aldolase (EC 4.1.2.5) | 0.68 | GFF4447 | | Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | — | — |
| Pseudomonas segetis P6 | 0.54 | ACVTMO_RS15855 | ltaE | low-specificity L-threonine aldolase | 0.60 | ACVTMO_RS11215 | folD | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Pseudomonas sp. DMC3 | 0.54 | GFF4871 | | Low specificity L-threonine aldolase | 0.61 | GFF1441 | | Bifunctional protein FolD protein | — | — |
| Klebsiella michiganensis M5al | 0.54 | BWI76_RS09550 | | low-specificity L-threonine aldolase | 0.68 | BWI76_RS07100 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase | — | — |
| Klebsiella pneumoniae MKP103 | 0.53 | KDGMDA_17800 | | low-specificity L-threonine aldolase | 0.68 | KDGMDA_15035 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Pseudomonas lactucae CFBP13502 | 0.53 | GEMAOFIL_04477 | | Low specificity L-threonine aldolase | 0.61 | GEMAOFIL_03749 | | Bifunctional protein FolD protein | — | — |
| Escherichia coli ECRC62 | 0.53 | BNILDI_20500 | ltaE | low-specificity L-threonine aldolase | 0.67 | BNILDI_22225 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.53 | OHPLBJKB_02798 | | Low specificity L-threonine aldolase | 0.68 | OHPLBJKB_03152 | | Bifunctional protein FolD protein | — | — |
| Escherichia fergusonii Becca | 0.53 | EFB2_03191 | | Low specificity L-threonine aldolase | 0.68 | EFB2_03532 | | Bifunctional protein FolD protein | — | — |
| Escherichia coli ECOR27 | 0.53 | NOLOHH_22245 | ltaE | low-specificity L-threonine aldolase | 0.68 | NOLOHH_00795 | | Bifunctional protein FolD | — | — |
| Rahnella sp. WP5 | 0.53 | EX31_RS18605 | | low-specificity L-threonine aldolase | 0.69 | EX31_RS22835 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Escherichia coli BL21 | 0.53 | ECD_00875 | | L-allo-threonine aldolase, PLP-dependent | 0.68 | ECD_00479 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase | — | — |
| Escherichia coli BW25113 | 0.53 | b0870 | ltaE | L-allo-threonine aldolase, PLP-dependent (NCBI) | 0.68 | b0529 | folD | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase (NCBI) | — | — |
| Enterobacter asburiae PDN3 | 0.53 | EX28DRAFT_2063 | | L-threonine aldolase (EC 4.1.2.5) | 0.68 | EX28DRAFT_2449 | | 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase | — | — |
| Escherichia coli ECRC99 | 0.53 | KEDOAH_22060 | ltaE | low-specificity L-threonine aldolase | 0.68 | KEDOAH_20165 | | Bifunctional protein FolD | — | — |
| Klebsiella pneumoniae MRSN742743 | 0.53 | KFA93_RS01085 | ltaE;go_function=lyase | low-specificity L-threonine aldolase | 0.68 | KFA93_RS03235 | folD;go_function=methylenetetrahydrofolate | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Escherichia coli ECRC98 | 0.53 | JDDGAC_09485 | ltaE | low-specificity L-threonine aldolase | 0.68 | JDDGAC_11455 | | Bifunctional protein FolD | — | — |
| Escherichia coli ECRC101 | 0.53 | MCAODC_25065 | ltaE | low-specificity L-threonine aldolase | 0.68 | MCAODC_27025 | | Bifunctional protein FolD | — | — |
| Escherichia coli ECRC100 | 0.53 | OKFHMN_05850 | ltaE | low-specificity L-threonine aldolase | 0.68 | OKFHMN_07805 | | Bifunctional protein FolD | — | — |
| Escherichia coli ECOR38 | 0.53 | HEPCGN_02165 | ltaE | low-specificity L-threonine aldolase | 0.67 | HEPCGN_06445 | | Bifunctional protein FolD | — | — |
| Escherichia coli ECRC102 | 0.53 | NIAGMN_03890 | ltaE | low-specificity L-threonine aldolase | 0.68 | NIAGMN_05860 | | Bifunctional protein FolD | — | — |
| Escherichia coli Nissle 1917 | 0.53 | ECOLIN_RS04630 | | low-specificity L-threonine aldolase | 0.68 | ECOLIN_RS03065 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Pseudomonas stutzeri RCH2 | 0.53 | Psest_2990 | | Threonine aldolase | 0.58 | Psest_2301 | | 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase | — | — |
| Enterobacter sp. TBS_079 | 0.53 | MPMX20_01531 | | Low specificity L-threonine aldolase | 0.68 | MPMX20_01107 | | Bifunctional protein FolD protein | — | — |
| Paraburkholderia graminis OAS925 | 0.52 | ABIE53_005128 | | threonine aldolase | 0.42 | ABIE53_002796 | | methylenetetrahydrofolate dehydrogenase (NADP+)/methenyltetrahydrofolate cyclohydrolase | — | — |
| Kangiella aquimarina DSM 16071 | 0.52 | B158DRAFT_1832 | | L-threonine aldolase (EC 4.1.2.5) | 0.57 | B158DRAFT_1028 | | methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9)/5,10-methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) | — | — |
| Pseudomonas aeruginosa PA14 | 0.52 | IKLFDK_04020 | | low-specificity L-threonine aldolase | 0.62 | IKLFDK_08690 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Pseudomonas aeruginosa MRSN321 | 0.52 | DY961_RS07960 | ltaE;go_function=lyase | low-specificity L-threonine aldolase | 0.62 | DY961_RS20675 | folD;go_function=methylenetetrahydrofolate | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Pseudomonas aeruginosa PUPa3 | 0.52 | DQ20_RS44840 | ltaE;go_function=lyase | low-specificity L-threonine aldolase | 0.62 | DQ20_RS54755 | folD;go_function=methylenetetrahydrofolate | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Lysobacter sp. OAE881 | 0.52 | ABIE51_RS01760 | | low-specificity L-threonine aldolase | 0.52 | ABIE51_RS09470 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Erwinia amylovora T8 | 0.51 | OLJFJH_16245 | | low-specificity L-threonine aldolase | 0.67 | OLJFJH_17600 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.51 | H281DRAFT_03052 | | L-threonine aldolase | 0.42 | H281DRAFT_00463 | | methenyltetrahydrofolate cyclohydrolase /5,10-methylenetetrahydrofolate dehydrogenase (NADP+) | — | — |
| Pantoea sp. MT58 | 0.51 | IAI47_12975 | | low-specificity L-threonine aldolase | 0.68 | IAI47_14320 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Pantoea agglomerans CFBP13505 P0401 | 0.51 | PagCFBP13516_RS13060 | ltaE | low-specificity L-threonine aldolase | 0.68 | PagCFBP13516_RS14565 | folD | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Variovorax sp. OAS795 | 0.50 | ABID97_RS05265 | | low-specificity L-threonine aldolase | 0.44 | ABID97_RS14085 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Rhodanobacter denitrificans FW104-10B01 | 0.50 | LRK54_RS12390 | | low-specificity L-threonine aldolase | 0.55 | LRK54_RS00100 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Rhodanobacter denitrificans MT42 | 0.50 | LRK55_RS12125 | | low-specificity L-threonine aldolase | 0.55 | LRK55_RS18095 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Rhodanobacter sp000427505 FW510-R12 | 0.50 | LRK53_RS16110 | | low-specificity L-threonine aldolase | 0.56 | LRK53_RS11165 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Burkholderia phytofirmans PsJN | 0.50 | BPHYT_RS29600 | | threonine aldolase | 0.42 | BPHYT_RS12865 | | bifunctional protein FolD | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.49 | ABZR86_RS19205 | | low-specificity L-threonine aldolase | 0.54 | ABZR86_RS05415 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.49 | QEN71_RS14320 | | low-specificity L-threonine aldolase | 0.43 | QEN71_RS05700 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Variovorax sp. SCN45 | 0.49 | GFF5893 | | Low-specificity L-threonine aldolase (EC 4.1.2.48) | 0.44 | GFF964 | | Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) / Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) | — | — |
| Rhodanobacter sp. FW510-T8 | 0.48 | OKGIIK_11545 | ltaE | low-specificity L-threonine aldolase | 0.54 | OKGIIK_07100 | folD | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Acidovorax sp. GW101-3H11 | 0.47 | Ac3H11_4475 | | Low-specificity L-threonine aldolase (EC 4.1.2.48) | 0.45 | Ac3H11_4096 | | Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.45 | GFF3108 | | Low-specificity L-threonine aldolase (EC 4.1.2.48) | 0.45 | GFF4894 | | Methylenetetrahydrofolate dehydrogenase (NADP+) (EC 1.5.1.5) / Methenyltetrahydrofolate cyclohydrolase (EC 3.5.4.9) | — | — |
| Ralstonia sp. UNC404CL21Col | 0.45 | ABZR87_RS05825 | | low-specificity L-threonine aldolase | 0.45 | ABZR87_RS13485 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
| Pontibacter actiniarum KMM 6156, DSM 19842 | 0.36 | CA264_06480 | | threonine aldolase | 0.43 | CA264_07145 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase | — | — |
| Dinoroseobacter shibae DFL-12 | 0.36 | Dshi_2144 | | Threonine aldolase (RefSeq) | 0.37 | Dshi_1285 | | Methylenetetrahydrofolate dehydrogenase (NADP(+)) (RefSeq) | — | — |
| Pedobacter sp. GW460-11-11-14-LB5 | 0.35 | CA265_RS02210 | | threonine aldolase | 0.38 | CA265_RS08950 | | bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/5,10-methylene-tetrahydrofolate cyclohydrolase | — | — |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | 0.34 | ABZR88_RS09335 | | low specificity L-threonine aldolase | 0.39 | ABZR88_RS09400 | | bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase | — | — |
| Echinicola vietnamensis KMM 6221, DSM 17526 | 0.32 | Echvi_4604 | | Threonine aldolase | 0.43 | Echvi_4643 | | 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase | — | — |
| Cellulophaga baltica 18 | 0.31 | M666_RS13845 | | GntG family PLP-dependent aldolase | 0.41 | M666_RS00795 | | bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/5,10-methenyltetrahydrofolate cyclohydrolase | — | — |
| Rhodopseudomonas palustris CGA009 | 0.30 | TX73_008155 | | threonine aldolase family protein | 0.39 | TX73_002145 | | bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD | — | — |
Not shown: 0 genomes with orthologs for CSW01_18005 only; 50 genomes with orthologs for CSW01_09720 only