Conservation of cofitness between CSW01_02550 and CSW01_06950 in Vibrio cholerae E7946 ATCC 55056

75 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02550 mechanosensitive ion channel protein 1.0 CSW01_06950 ATP-dependent RNA helicase HrpA 0.56 16
Klebsiella pneumoniae MKP103 0.53 KDGMDA_04445 mechanosensitive ion channel protein MscS 0.71 KDGMDA_20775 ATP-dependent RNA helicase HrpA low > 95
Klebsiella michiganensis M5al 0.52 BWI76_RS23970 mechanosensitive ion channel protein MscS 0.70 BWI76_RS13165 ATP-dependent RNA helicase HrpA low > 92
Shewanella sp. ANA-3 0.52 Shewana3_1206 MscS mechanosensitive ion channel (RefSeq) 0.57 Shewana3_1897 ATP-dependent helicase HrpA (RefSeq) low > 73
Shewanella oneidensis MR-1 0.51 SO3340 hypothetical Small-conductance mechanosensitive channel (NCBI ptt file) 0.57 SO2229 hrpA ATP-dependent helicase HrpA (NCBI ptt file) low > 76
Erwinia tracheiphila HP pepo 2.2 0.51 IJEDHG_03355 mechanosensitive ion channel protein MscS 0.69 IJEDHG_23640 hrpA ATP-dependent RNA helicase HrpA low > 61
Serratia liquefaciens MT49 0.51 IAI46_20995 small-conductance mechanosensitive channel MscS 0.70 IAI46_13330 ATP-dependent RNA helicase HrpA low > 87
Erwinia tracheiphila SCR3 0.51 LU632_RS05550 mscS small-conductance mechanosensitive channel MscS 0.69 LU632_RS12630 hrpA ATP-dependent RNA helicase HrpA — —
Rahnella sp. WP5 0.50 EX31_RS21435 small-conductance mechanosensitive channel MscS 0.70 EX31_RS06495 ATP-dependent RNA helicase HrpA low > 89
Shewanella loihica PV-4 0.50 Shew_1152 MscS mechanosensitive ion channel (RefSeq) 0.57 Shew_1767 ATP-dependent helicase HrpA (RefSeq) low > 60
Escherichia fergusonii Becca 0.50 EFB2_00982 Small-conductance mechanosensitive channel 0.71 EFB2_02565 hypothetical protein low > 86
Shewanella amazonensis SB2B 0.50 Sama_2465 putative small-conductance mechanosensitive channel (RefSeq) 0.57 Sama_1619 ATP-dependent helicase HrpA (RefSeq) — —
Escherichia coli Nissle 1917 0.50 ECOLIN_RS16250 small-conductance mechanosensitive channel MscS 0.71 ECOLIN_RS08180 ATP-dependent RNA helicase HrpA — —
Escherichia coli BL21 0.50 ECD_02755 mechanosensitive channel protein, small conductance 0.71 ECD_01368 putative ATP-dependent helicase low > 61
Escherichia coli ECRC100 0.50 OKFHMN_19405 mscS small-conductance mechanosensitive channel MscS 0.71 OKFHMN_01730 hrpA ATP-dependent RNA helicase HrpA low > 79
Escherichia coli ECRC102 0.50 NIAGMN_17170 mscS small-conductance mechanosensitive channel MscS 0.71 NIAGMN_25865 hrpA ATP-dependent RNA helicase HrpA low > 80
Escherichia coli HS(pFamp)R (ATCC 700891) 0.50 OHPLBJKB_00792 Small-conductance mechanosensitive channel 0.71 OHPLBJKB_02301 hypothetical protein low > 74
Escherichia coli ECOR27 0.50 NOLOHH_11315 mscS small-conductance mechanosensitive channel MscS 0.71 NOLOHH_19390 hrpA ATP-dependent RNA helicase HrpA low > 76
Escherichia coli ECRC101 0.50 MCAODC_09925 mscS small-conductance mechanosensitive channel MscS 0.71 MCAODC_16205 hrpA ATP-dependent RNA helicase HrpA low > 87
Escherichia coli ECRC98 0.50 JDDGAC_23035 mscS small-conductance mechanosensitive channel MscS 0.71 JDDGAC_04220 hrpA ATP-dependent RNA helicase HrpA low > 87
Escherichia coli ECRC62 0.50 BNILDI_09850 mscS small-conductance mechanosensitive channel MscS 0.71 BNILDI_17845 hrpA ATP-dependent RNA helicase HrpA low > 75
Escherichia coli ECOR38 0.50 HEPCGN_18710 mscS small-conductance mechanosensitive channel MscS 0.71 HEPCGN_26110 hrpA ATP-dependent RNA helicase HrpA low > 88
Escherichia coli BW25113 0.50 b2924 mscS mechanosensitive channel (NCBI) 0.71 b1413 hrpA ATP-dependent helicase (RefSeq) low > 76
Escherichia coli ECRC99 0.50 KEDOAH_08735 mscS small-conductance mechanosensitive channel MscS 0.71 KEDOAH_26710 hrpA ATP-dependent RNA helicase HrpA — —
Pantoea sp. MT58 0.49 IAI47_03700 small-conductance mechanosensitive channel MscS 0.70 IAI47_09520 ATP-dependent RNA helicase HrpA low > 76
Dickeya dadantii 3937 0.49 DDA3937_RS18505 small-conductance mechanosensitive channel MscS 0.69 DDA3937_RS12270 ATP-dependent RNA helicase HrpA low > 74
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.48 GFF3019 Protein involved in stability of MscS mechanosensitive channel 0.72 GFF2632 ATP-dependent RNA helicase HrpA (EC 3.6.4.13) low > 78
Alteromonas macleodii MIT1002 0.48 MIT1002_03053 Small-conductance mechanosensitive channel 0.55 MIT1002_01685 ATP-dependent RNA helicase HrpB — —
Dickeya dianthicola 67-19 0.48 HGI48_RS18430 small-conductance mechanosensitive channel MscS 0.69 HGI48_RS12360 ATP-dependent RNA helicase HrpA low > 71
Dickeya dianthicola ME23 0.47 DZA65_RS19565 small-conductance mechanosensitive channel MscS 0.69 DZA65_RS12800 ATP-dependent RNA helicase HrpA low > 75
Pectobacterium carotovorum WPP14 0.47 HER17_RS02700 small-conductance mechanosensitive channel MscS 0.69 HER17_RS09660 ATP-dependent RNA helicase HrpA low > 75
Enterobacter sp. TBS_079 0.47 MPMX20_03776 Small-conductance mechanosensitive channel 0.71 MPMX20_02189 hypothetical protein low > 85
Enterobacter asburiae PDN3 0.46 EX28DRAFT_2970 Small-conductance mechanosensitive channel 0.71 EX28DRAFT_1357 RNA helicase HrpA low > 76
Pantoea agglomerans CFBP13505 P0401 0.45 PagCFBP13505_RS16000 small-conductance mechanosensitive channel MscS 0.70 PagCFBP13505_RS06635 ATP-dependent RNA helicase HrpA low > 74
Kangiella aquimarina DSM 16071 0.43 B158DRAFT_2270 Small-conductance mechanosensitive channel 0.38 B158DRAFT_1779 ATP-dependent helicase HrpA low > 40
Pseudomonas stutzeri RCH2 0.41 Psest_1143 Small-conductance mechanosensitive channel 0.43 Psest_1339 ATP-dependent helicase HrpA low > 67
Erwinia amylovora T8 0.41 OLJFJH_08665 mechanosensitive ion channel protein MscS 0.69 OLJFJH_13820 ATP-dependent RNA helicase HrpA low > 58
Pseudomonas segetis P6 0.41 ACVTMO_RS18740 mechanosensitive ion channel family protein 0.43 ACVTMO_RS16215 hrpA ATP-dependent RNA helicase HrpA low > 75
Marinobacter adhaerens HP15 0.40 HP15_3381 MscS mechanosensitive ion channel 0.44 HP15_1863 RNA helicase, ATP-dependent DEAH box, HrpA type low > 73
Pseudomonas lactucae CFBP13502 0.40 GEMAOFIL_04653 Small-conductance mechanosensitive channel 0.45 GEMAOFIL_04265 hypothetical protein low > 96
Pseudomonas simiae WCS417 0.40 PS417_22505 mechanosensitive ion channel protein MscS 0.44 PS417_20575 ATP-dependent helicase HrpA low > 88
Pseudomonas sp. RS175 0.40 PFR28_03424 Small-conductance mechanosensitive channel 0.44 PFR28_00739 hypothetical protein low > 88
Pseudomonas fluorescens SBW25 0.39 PFLU_RS24145 mechanosensitive ion channel 0.45 PFLU_RS22265 ATP-dependent RNA helicase HrpA low > 109
Pseudomonas fluorescens SBW25-INTG 0.39 PFLU_RS24145 mechanosensitive ion channel 0.45 PFLU_RS22265 ATP-dependent RNA helicase HrpA low > 109
Pseudomonas orientalis W4I3 0.39 QF045_RS24670 mechanosensitive ion channel family protein 0.45 QF045_RS22485 ATP-dependent RNA helicase HrpA low > 93
Pseudomonas sp. DMC3 0.36 GFF5197 Small-conductance mechanosensitive channel 0.45 GFF2341 hypothetical protein low > 89
Pseudomonas fluorescens GW456-L13 0.36 PfGW456L13_1841 Small-conductance mechanosensitive channel 0.45 PfGW456L13_4467 ATP-dependent RNA helicase HrpA (EC 3.6.4.13) low > 87
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_17965 mechanosensitive ion channel protein MscS 0.45 AO356_04280 ATP-dependent RNA helicase HrpA low > 104
Pseudomonas sp. BP01 0.35 JOY50_RS15030 mechanosensitive ion channel family protein 0.44 JOY50_RS01295 hrpA ATP-dependent RNA helicase HrpA low > 84
Pseudomonas fluorescens FW300-N1B4 0.35 Pf1N1B4_649 Small-conductance mechanosensitive channel 0.45 Pf1N1B4_3388 ATP-dependent RNA helicase HrpA (EC 3.6.4.13) low > 87
Pseudomonas fluorescens FW300-N2E2 0.35 Pf6N2E2_5523 Small-conductance mechanosensitive channel 0.45 Pf6N2E2_2694 ATP-dependent RNA helicase HrpA (EC 3.6.4.13) low > 103
Dyella japonica UNC79MFTsu3.2 0.35 ABZR86_RS12290 mechanosensitive ion channel domain-containing protein 0.37 ABZR86_RS19720 ATP-dependent RNA helicase HrpA low > 74
Pseudomonas aeruginosa PUPa3 0.34 DQ20_RS56965 mechanosensitive ion channel family protein 0.45 DQ20_RS40625 hrpA;go_function=helicase ATP-dependent RNA helicase HrpA low > 101
Pseudomonas aeruginosa MRSN321 0.34 DY961_RS24515 mechanosensitive ion channel family protein 0.45 DY961_RS00395 hrpA;go_function=helicase ATP-dependent RNA helicase HrpA low > 100
Pseudomonas aeruginosa PA14 0.34 IKLFDK_02125 mechanosensitive ion channel protein MscS 0.45 IKLFDK_16885 ATP-dependent RNA helicase HrpA low > 98
Pseudomonas fluorescens FW300-N2E3 0.34 AO353_03635 mechanosensitive ion channel protein MscS 0.45 AO353_18225 ATP-dependent RNA helicase HrpA low > 101
Pseudomonas sp. SVBP6 0.34 COO64_RS11980 mechanosensitive ion channel family protein 0.45 COO64_RS22000 hrpA ATP-dependent RNA helicase HrpA 0.46 25
Pseudomonas putida KT2440 0.34 PP_1353 conserved membrane protein of unknown function 0.44 PP_4546 ATP-dependent helicase HrpA 0.33 38
Cupriavidus basilensis FW507-4G11 0.33 RR42_RS37450 mechanosensitive ion channel protein MscS 0.41 RR42_RS13030 ATP-dependent helicase low > 128
Rhodanobacter sp000427505 FW510-R12 0.32 LRK53_RS04170 mechanosensitive ion channel 0.36 LRK53_RS15885 ATP-dependent RNA helicase HrpA low > 59
Castellaniella sp019104865 MT123 0.31 ABCV34_RS00345 mechanosensitive ion channel family protein 0.39 ABCV34_RS02420 ATP-dependent RNA helicase HrpA low > 48
Pseudomonas sp. S08-1 0.31 OH686_08205 Small-conductance mechanosensitive channel 0.43 OH686_05730 RNA helicase HrpA low > 80
Rhodanobacter denitrificans MT42 0.31 LRK55_RS10980 mechanosensitive ion channel 0.34 LRK55_RS12420 ATP-dependent RNA helicase HrpA low > 63
Rhodanobacter denitrificans FW104-10B01 0.31 LRK54_RS11275 mechanosensitive ion channel 0.34 LRK54_RS12715 ATP-dependent RNA helicase HrpA low > 59
Rhodanobacter sp. FW510-T8 0.30 OKGIIK_12610 Small-conductance mechanosensitive channel 0.33 OKGIIK_02155 hrpA ATP-dependent RNA helicase HrpA low > 53
Pseudomonas syringae pv. syringae B728a 0.30 Psyr_4086 MscS Mechanosensitive ion channel 0.44 Psyr_3831 ATP-dependent helicase HrpA low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.30 Psyr_4086 MscS Mechanosensitive ion channel 0.44 Psyr_3831 ATP-dependent helicase HrpA low > 86
Ralstonia solanacearum GMI1000 0.26 RS_RS13330 mechanosensitive ion channel family protein 0.41 RS_RS06270 ATP-dependent RNA helicase HrpA low > 80
Ralstonia solanacearum UW163 0.26 UW163_RS08150 mechanosensitive ion channel family protein 0.41 UW163_RS12950 ATP-dependent RNA helicase HrpA — —
Ralstonia solanacearum IBSBF1503 0.26 RALBFv3_RS05475 mechanosensitive ion channel family protein 0.41 RALBFv3_RS15490 ATP-dependent RNA helicase HrpA low > 76
Ralstonia solanacearum PSI07 0.25 RPSI07_RS11830 mechanosensitive ion channel family protein 0.41 RPSI07_RS17865 ATP-dependent RNA helicase HrpA low > 81
Ralstonia sp. UNC404CL21Col 0.25 ABZR87_RS01115 mechanosensitive ion channel family protein 0.40 ABZR87_RS11020 ATP-dependent RNA helicase HrpA low > 80
Paraburkholderia sabiae LMG 24235 0.25 QEN71_RS26425 mechanosensitive ion channel family protein 0.37 QEN71_RS05625 ATP-dependent RNA helicase HrpA low > 153
Burkholderia phytofirmans PsJN 0.23 BPHYT_RS06305 small mechanosensitive ion channel protein MscS 0.36 BPHYT_RS12980 ATP-dependent helicase low > 109
Herbaspirillum seropedicae SmR1 0.23 HSERO_RS17760 mechanosensitive ion channel protein MscS 0.40 HSERO_RS17315 ATP-dependent helicase low > 78
Hydrogenophaga sp. GW460-11-11-14-LB1 0.16 GFF1625 Potassium efflux system KefA protein / Small-conductance mechanosensitive channel 0.37 GFF4301 macromolecule metabolism; macromolecule synthesis, modification; dna - replication, repair, restr./modif. low > 90

Not shown: 22 genomes with orthologs for CSW01_02550 only; 9 genomes with orthologs for CSW01_06950 only