| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_03930 | | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 1.0 | CSW01_03285 | | AI-2E family transporter | 0.43 | 17 |
| Escherichia coli BW25113 | 0.74 | b2517 | yfgB | predicted enzyme (NCBI) | 0.17 | b1688 | ydiK | predicted inner membrane protein (NCBI) | low | > 76 |
| Escherichia coli BL21 | 0.74 | ECD_02409 | | dual specificity 23S rRNA m(2)A2503, tRNA m(2)A37 methyltransferase, SAM-dependent | 0.17 | ECD_01657 | | UPF0118 family inner membrane protein | low | > 61 |
| Escherichia coli ECOR27 | 0.74 | NOLOHH_13360 | rlmN | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.17 | NOLOHH_17745 | ydiK | AI-2E family transporter YdiK | low | > 76 |
| Escherichia coli ECRC62 | 0.74 | BNILDI_12160 | rlmN | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.17 | BNILDI_16535 | ydiK | AI-2E family transporter YdiK | low | > 75 |
| Escherichia coli Nissle 1917 | 0.74 | ECOLIN_RS14300 | | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.17 | ECOLIN_RS09435 | | AI-2E family transporter YdiK | — | — |
| Escherichia coli ECOR38 | 0.74 | HEPCGN_20830 | rlmN | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.17 | HEPCGN_05610 | ydiK | AI-2E family transporter YdiK | low | > 88 |
| Escherichia fergusonii Becca | 0.74 | EFB2_01373 | | Dual-specificity RNA methyltransferase RlmN | 0.17 | EFB2_02304 | | Putative transport protein YdiK | low | > 86 |
| Escherichia coli ECRC101 | 0.74 | MCAODC_12240 | rlmN | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.17 | MCAODC_18185 | ydiK | AI-2E family transporter YdiK | low | > 87 |
| Escherichia coli ECRC99 | 0.74 | KEDOAH_06510 | rlmN | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.17 | KEDOAH_00885 | ydiK | AI-2E family transporter YdiK | — | — |
| Escherichia coli ECRC102 | 0.74 | NIAGMN_19480 | rlmN | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.17 | NIAGMN_00840 | ydiK | AI-2E family transporter YdiK | low | > 80 |
| Escherichia coli ECRC100 | 0.74 | OKFHMN_21710 | rlmN | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.17 | OKFHMN_27225 | ydiK | AI-2E family transporter YdiK | low | > 79 |
| Escherichia coli ECRC98 | 0.74 | JDDGAC_25385 | rlmN | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.17 | JDDGAC_01800 | ydiK | AI-2E family transporter YdiK | low | > 87 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.74 | OHPLBJKB_01192 | | Dual-specificity RNA methyltransferase RlmN | 0.17 | OHPLBJKB_02036 | | Putative transport protein YdiK | low | > 74 |
| Klebsiella michiganensis M5al | 0.74 | BWI76_RS21095 | | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.24 | BWI76_RS19855 | | AI-2E family transporter | low | > 92 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.74 | GFF2414 | | Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) | 0.15 | GFF3553 | | Putative membrane protein | low | > 78 |
| Enterobacter asburiae PDN3 | 0.74 | EX28DRAFT_0126 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase | 0.23 | EX28DRAFT_2609 | | Predicted permease | low | > 76 |
| Enterobacter sp. TBS_079 | 0.74 | MPMX20_03395 | | Dual-specificity RNA methyltransferase RlmN | 0.23 | MPMX20_00952 | | Putative transport protein YdiK | low | > 85 |
| Klebsiella pneumoniae MKP103 | 0.74 | KDGMDA_28215 | | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.24 | KDGMDA_26805 | | AI-2E family transporter | low | > 95 |
| Erwinia tracheiphila SCR3 | 0.74 | LU632_RS17815 | | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.15 | LU632_RS11035 | ydiK | AI-2E family transporter YdiK | low | > 73 |
| Pantoea agglomerans CFBP13505 P0401 | 0.73 | PagCFBP13505_RS14930 | | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.24 | PagCFBP13505_RS03120 | | AI-2E family transporter | low | > 74 |
| Erwinia amylovora T8 | 0.73 | OLJFJH_10435 | | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.21 | OLJFJH_12970 | | AI-2E family transporter | low | > 58 |
| Dickeya dadantii 3937 | 0.73 | DDA3937_RS15480 | | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.17 | DDA3937_RS12800 | | AI-2E family transporter YdiK | low | > 74 |
| Dickeya dianthicola ME23 | 0.73 | DZA65_RS16665 | | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.17 | DZA65_RS13330 | | AI-2E family transporter YdiK | low | > 75 |
| Dickeya dianthicola 67-19 | 0.73 | HGI48_RS15590 | | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.16 | HGI48_RS12865 | | AI-2E family transporter YdiK | low | > 71 |
| Serratia liquefaciens MT49 | 0.73 | IAI46_19290 | | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.21 | IAI46_10470 | | AI-2E family transporter | low | > 87 |
| Pantoea sp. MT58 | 0.73 | IAI47_05040 | | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.25 | IAI47_14150 | | AI-2E family transporter | low | > 76 |
| Erwinia tracheiphila HP pepo 2.2 | 0.73 | IJEDHG_02785 | rlmN | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.15 | IJEDHG_25320 | ydiK | AI-2E family transporter YdiK | low | > 61 |
| Rahnella sp. WP5 | 0.72 | EX31_RS20525 | | bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN | 0.22 | EX31_RS10525 | | AI-2E family transporter | low | > 89 |
| Shewanella sp. ANA-3 | 0.71 | Shewana3_1226 | | hypothetical protein (RefSeq) | 0.13 | Shewana3_0477 | | hypothetical protein (RefSeq) | low | > 73 |
| Shewanella oneidensis MR-1 | 0.71 | SO3315 | | conserved hypothetical protein TIGR00048 (NCBI ptt file) | 0.13 | SO0472 | | membrane protein, putative (NCBI ptt file) | low | > 76 |
| Pseudomonas syringae pv. syringae B728a | 0.55 | Psyr_1245 | | 23S rRNA m(2)A-2503 methyltransferase | 0.21 | Psyr_3210 | | Protein of unknown function UPF0118 | low | > 86 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.55 | Psyr_1245 | | 23S rRNA m(2)A-2503 methyltransferase | 0.21 | Psyr_3210 | | Protein of unknown function UPF0118 | low | > 86 |
| Pseudomonas orientalis W4I3 | 0.55 | QF045_RS25380 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.22 | QF045_RS12380 | | AI-2E family transporter | low | > 93 |
| Pseudomonas simiae WCS417 | 0.55 | PS417_23160 | | 50S rRNA methyltransferase | 0.21 | PS417_10400 | | membrane protein | low | > 88 |
| Pseudomonas fluorescens SBW25-INTG | 0.55 | PFLU_RS24815 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.21 | PFLU_RS10475 | | AI-2E family transporter | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.55 | PFLU_RS24815 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.21 | PFLU_RS10475 | | AI-2E family transporter | low | > 109 |
| Pseudomonas lactucae CFBP13502 | 0.55 | GEMAOFIL_04784 | | Dual-specificity RNA methyltransferase RlmN | 0.22 | GEMAOFIL_02170 | | Putative transport protein YdiK | low | > 96 |
| Pseudomonas fluorescens FW300-N2E3 | 0.55 | AO353_15875 | | 23S rRNA (adenine(2503)-C2)-methyltransferase | 0.21 | AO353_19805 | | hypothetical protein | low | > 101 |
| Pseudomonas fluorescens FW300-N2E2 | 0.55 | Pf6N2E2_3181 | | Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) | 0.21 | Pf6N2E2_46 | | membrane protein, putative | — | — |
| Pseudomonas sp. SVBP6 | 0.55 | COO64_RS03935 | rlmN | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.21 | COO64_RS24345 | | AI-2E family transporter | low | > 93 |
| Pseudomonas fluorescens FW300-N2C3 | 0.55 | AO356_06605 | | 23S rRNA (adenine(2503)-C2)-methyltransferase | 0.22 | AO356_21305 | | hypothetical protein | low | > 104 |
| Pseudomonas sp. DMC3 | 0.54 | GFF4342 | | Dual-specificity RNA methyltransferase RlmN | 0.20 | GFF1423 | | Putative transport protein YdiK | low | > 89 |
| Pseudomonas fluorescens GW456-L13 | 0.54 | PfGW456L13_4865 | | Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) | 0.21 | PfGW456L13_2486 | | membrane protein, putative | low | > 87 |
| Pseudomonas aeruginosa MRSN321 | 0.54 | DY961_RS13890 | rlmN;go_function=S-adenosylmethionine-dependent | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.25 | DY961_RS03960 | | AI-2E family transporter | low | > 100 |
| Pseudomonas aeruginosa PUPa3 | 0.54 | DQ20_RS43210 | rlmN;go_function=S-adenosylmethionine-dependent | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.25 | DQ20_RS34990 | | AI-2E family transporter | low | > 101 |
| Pseudomonas aeruginosa PA14 | 0.54 | IKLFDK_19600 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.25 | IKLFDK_13310 | | AI-2E family transporter | low | > 98 |
| Pseudomonas fluorescens FW300-N1B4 | 0.54 | Pf1N1B4_857 | | Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) | 0.22 | Pf1N1B4_3926 | | membrane protein, putative | — | — |
| Pseudomonas segetis P6 | 0.54 | MPMX49_01515 | | Dual-specificity RNA methyltransferase RlmN | 0.12 | MPMX49_02677 | | Putative transport protein YdiK | low | > 75 |
| Pseudomonas sp. RS175 | 0.54 | PFR28_00294 | | Dual-specificity RNA methyltransferase RlmN | 0.21 | PFR28_02842 | | Putative transport protein YdiK | low | > 88 |
| Pseudomonas stutzeri RCH2 | 0.54 | Psest_1259 | | 23S rRNA m2A2503 methyltransferase | 0.24 | Psest_2012 | | Predicted permease | low | > 67 |
| Pseudomonas putida KT2440 | 0.54 | PP_0850 | | Dual-specificity RNA methyltransferase RlmN | 0.21 | PP_2207 | | conserved membrane protein of unknown function | low | > 96 |
| Pseudomonas sp. BP01 | 0.53 | JOY50_RS22780 | rlmN | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.22 | JOY50_RS12685 | | AI-2E family transporter | low | > 84 |
| Pseudomonas sp. S08-1 | 0.53 | OH686_17515 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase | 0.22 | OH686_00090 | | Uncharacterized UPF0118 membrane protein | low | > 80 |
| Marinobacter adhaerens HP15 | 0.52 | HP15_1490 | | conserved hypothetical protein | 0.22 | HP15_593 | | protein belonging to uncharacterized protein family UPF0118 | low | > 73 |
| Dechlorosoma suillum PS | 0.51 | Dsui_3145 | | 23S rRNA m2A2503 methyltransferase | 0.16 | Dsui_0423 | | putative permease | — | — |
| Acinetobacter radioresistens SK82 | 0.50 | MPMX26_00426 | | Dual-specificity RNA methyltransferase RlmN | 0.12 | MPMX26_02768 | | Putative transport protein YdiK | low | > 36 |
| Cupriavidus basilensis FW507-4G11 | 0.50 | RR42_RS13155 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.23 | RR42_RS15425 | | membrane protein | — | — |
| Acinetobacter baumannii LAC-4 | 0.50 | RR41_RS16460 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.14 | RR41_RS01810 | | AI-2E family transporter | low | > 55 |
| Ralstonia sp. UNC404CL21Col | 0.49 | ABZR87_RS10900 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.20 | ABZR87_RS08310 | | AI-2E family transporter | low | > 80 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.48 | GFF4866 | | Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) | 0.21 | GFF1907 | | membrane protein, putative | low | > 90 |
| Acidovorax sp. GW101-3H11 | 0.48 | Ac3H11_1791 | | Ribosomal RNA large subunit methyltransferase N (EC 2.1.1.-) | 0.21 | Ac3H11_2468 | | membrane protein, putative | low | > 79 |
| Variovorax sp. OAS795 | 0.48 | ABID97_RS14210 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.22 | ABID97_RS22290 | | AI-2E family transporter | low | > 91 |
| Variovorax sp. SCN45 | 0.47 | GFF992 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase @ tRNA (adenine(37)-C(2))-methyltransferase (EC 2.1.1.192) | 0.20 | GFF1804 | | Uncharacterized UPF0118 membrane protein | low | > 127 |
| Paraburkholderia sabiae LMG 24235 | 0.46 | QEN71_RS05965 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.19 | QEN71_RS09300 | | AI-2E family transporter | low | > 153 |
| Burkholderia phytofirmans PsJN | 0.46 | BPHYT_RS12590 | | dual-specificity RNA methyltransferase RlmN | 0.13 | BPHYT_RS06810 | | membrane protein | low | > 109 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.46 | H281DRAFT_00514 | | 23S rRNA m(2)A-2503 methyltransferase | 0.12 | H281DRAFT_04605 | | Predicted PurR-regulated permease PerM | — | — |
| Paraburkholderia graminis OAS925 | 0.45 | ABIE53_002744 | | 23S rRNA (adenine2503-C2)-methyltransferase | 0.13 | ABIE53_001629 | | putative PurR-regulated permease PerM | low | > 113 |
| Castellaniella sp019104865 MT123 | 0.43 | ABCV34_RS02610 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.20 | ABCV34_RS06025 | | AI-2E family transporter | low | > 48 |
| Rhodopseudomonas palustris CGA009 | 0.38 | TX73_002060 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.22 | TX73_002840 | | AI-2E family transporter | low | > 86 |
| Sinorhizobium meliloti 1021 | 0.37 | SMc03831 | | hypothetical protein | 0.21 | SM_b21335 | | hypothetical protein | low | > 103 |
| Xanthobacter sp. DMC5 | 0.36 | GFF1781 | | Dual-specificity RNA methyltransferase RlmN | 0.08 | GFF712 | | Putative transport protein YdiK | — | — |
| Rhizobium sp. OAE497 | 0.36 | ABIE40_RS18200 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN | 0.11 | ABIE40_RS09660 | | AI-2E family transporter | low | > 107 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.35 | DVU2904 | | radical SAM enzyme, Cfr family (TIGR) | 0.25 | DVU1189 | | conserved hypothetical protein (TIGR) | low | > 55 |
| Desulfovibrio vulgaris Miyazaki F | 0.34 | DvMF_1431 | | radical SAM enzyme, Cfr family (RefSeq) | 0.32 | DvMF_3082 | | protein of unknown function UPF0118 (RefSeq) | low | > 51 |
| Sphingobium sp. HT1-2 | 0.34 | GFF717 | | 23S rRNA (adenine(2503)-C(2))-methyltransferase @ tRNA (adenine(37)-C(2))-methyltransferase (EC 2.1.1.192) | 0.20 | GFF4818 | | Uncharacterized UPF0118 membrane protein | low | > 95 |
Not shown: 45 genomes with orthologs for CSW01_03930 only; 1 genomes with orthologs for CSW01_03285 only