| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_07180 | | tRNA 2-thiocytidine(32) synthetase TtcA | 1.0 | CSW01_02560 | | chromosome initiation inhibitor | 0.61 | 6 |
| Escherichia coli ECRC62 | 0.77 | BNILDI_18020 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.44 | BNILDI_09890 | argP | DNA-binding transcriptional regulator ArgP | low | > 75 |
| Escherichia coli ECRC101 | 0.77 | MCAODC_16100 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.44 | MCAODC_09970 | argP | DNA-binding transcriptional regulator ArgP | low | > 88 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.77 | OHPLBJKB_02337 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.44 | OHPLBJKB_00800 | | HTH-type transcriptional regulator ArgP | low | > 74 |
| Escherichia coli ECRC99 | 0.77 | KEDOAH_26600 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.44 | KEDOAH_08690 | argP | DNA-binding transcriptional regulator ArgP | — | — |
| Escherichia coli Nissle 1917 | 0.77 | ECOLIN_RS08065 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.44 | ECOLIN_RS16225 | | DNA-binding transcriptional regulator ArgP | — | — |
| Klebsiella michiganensis M5al | 0.77 | BWI76_RS12710 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.46 | BWI76_RS23930 | | transcriptional regulator ArgP | low | > 92 |
| Escherichia coli BL21 | 0.77 | ECD_01321 | | tRNA s(2)C32 thioltransferase, iron sulfur cluster protein | 0.44 | ECD_02747 | | transcriptional regulator for arginine transport and DNA replication genes; replication initiation inhibitor | low | > 61 |
| Escherichia coli ECRC102 | 0.77 | NIAGMN_26325 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.44 | NIAGMN_17215 | argP | DNA-binding transcriptional regulator ArgP | low | > 80 |
| Escherichia coli BW25113 | 0.77 | b1344 | ydaO | predicted C32 tRNA thiolase (NCBI) | 0.44 | b2916 | argP | chromosome replication initiation inhibitor protein (NCBI) | low | > 76 |
| Escherichia coli ECOR27 | 0.77 | NOLOHH_19870 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.44 | NOLOHH_11355 | argP | DNA-binding transcriptional regulator ArgP | low | > 76 |
| Enterobacter sp. TBS_079 | 0.77 | MPMX20_02440 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.45 | MPMX20_03773 | | HTH-type transcriptional regulator ArgP | low | > 85 |
| Pectobacterium carotovorum WPP14 | 0.76 | HER17_RS09605 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.44 | HER17_RS02715 | | LysR family transcriptional regulator ArgP | low | > 75 |
| Escherichia coli ECRC100 | 0.76 | OKFHMN_02155 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.44 | OKFHMN_19450 | argP | DNA-binding transcriptional regulator ArgP | — | — |
| Escherichia fergusonii Becca | 0.76 | EFB2_02583 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.44 | EFB2_00987 | | HTH-type transcriptional regulator ArgP | low | > 86 |
| Enterobacter asburiae PDN3 | 0.76 | EX28DRAFT_1007 | | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control | 0.45 | EX28DRAFT_2967 | | transcriptional regulator, ArgP family | low | > 76 |
| Escherichia coli ECOR38 | 0.76 | HEPCGN_26005 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.44 | HEPCGN_18750 | argP | DNA-binding transcriptional regulator ArgP | low | > 88 |
| Klebsiella pneumoniae MKP103 | 0.76 | KDGMDA_20605 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.46 | KDGMDA_04430 | | DNA-binding transcriptional regulator ArgP | low | > 95 |
| Dickeya dadantii 3937 | 0.76 | DDA3937_RS12330 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.45 | DDA3937_RS18490 | | LysR family transcriptional regulator ArgP | low | > 74 |
| Escherichia coli ECRC98 | 0.76 | JDDGAC_04715 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.44 | JDDGAC_23090 | argP | DNA-binding transcriptional regulator ArgP | low | > 87 |
| Dickeya dianthicola ME23 | 0.76 | DZA65_RS12850 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.46 | DZA65_RS19550 | | LysR family transcriptional regulator ArgP | low | > 75 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.76 | GFF2648 | | tRNA(Cytosine32)-2-thiocytidine synthetase | 0.46 | GFF3015 | | Chromosome initiation inhibitor | low | > 78 |
| Dickeya dianthicola 67-19 | 0.76 | HGI48_RS12410 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.46 | HGI48_RS18415 | | LysR family transcriptional regulator ArgP | low | > 71 |
| Pantoea agglomerans CFBP13505 P0401 | 0.75 | PagCFBP13505_RS06680 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.45 | PagCFBP13505_RS15985 | | LysR family transcriptional regulator ArgP | low | > 74 |
| Serratia liquefaciens MT49 | 0.75 | IAI46_13420 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.45 | IAI46_20910 | | LysR family transcriptional regulator ArgP | low | > 86 |
| Pantoea sp. MT58 | 0.75 | IAI47_09475 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.45 | IAI47_03715 | | LysR family transcriptional regulator ArgP | low | > 76 |
| Erwinia amylovora T8 | 0.74 | OLJFJH_13765 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.44 | OLJFJH_08715 | | HTH-type transcriptional regulator ArgP | low | > 58 |
| Rahnella sp. WP5 | 0.73 | EX31_RS06375 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.46 | EX31_RS21460 | | LysR family transcriptional regulator ArgP | low | > 89 |
| Alteromonas macleodii MIT1002 | 0.72 | MIT1002_02139 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.29 | MIT1002_00129 | | OriC replication inhibitor | low | > 70 |
| Pseudomonas sp. S08-1 | 0.64 | OH686_05145 | | tRNA-(cytosine32)-2-thiocytidine synthetase TtcA | 0.30 | OH686_07195 | | Transcriptional regulator ArgP, LysR family | low | > 80 |
| Pseudomonas stutzeri RCH2 | 0.64 | Psest_3033 | | Predicted ATPase of the PP-loop superfamily implicated in cell cycle control | 0.32 | Psest_1166 | | transcriptional regulator, ArgP family | low | > 67 |
| Shewanella amazonensis SB2B | 0.64 | Sama_1801 | | hypothetical protein (RefSeq) | 0.40 | Sama_2987 | | chromosome replication initiation inhibitor protein (RefSeq) | low | > 62 |
| Shewanella sp. ANA-3 | 0.64 | Shewana3_2117 | | PP-loop domain-containing protein (RefSeq) | 0.37 | Shewana3_1652 | | chromosome replication initiation inhibitor protein (RefSeq) | low | > 73 |
| Pseudomonas aeruginosa PA14 | 0.64 | IKLFDK_05600 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.34 | IKLFDK_02285 | | HTH-type transcriptional regulator ArgP | low | > 100 |
| Marinobacter adhaerens HP15 | 0.64 | HP15_2116 | | PP-loop domain protein | 0.30 | HP15_868 | | transcriptional regulator, LysR family | low | > 73 |
| Pseudomonas segetis P6 | 0.63 | MPMX49_01806 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.34 | MPMX49_03758 | | HTH-type transcriptional regulator ArgP | low | > 75 |
| Shewanella oneidensis MR-1 | 0.63 | SO2354 | | conserved hypothetical protein (NCBI ptt file) | 0.37 | SO2866 | iciA | chromosome initiation inhibitor (NCBI ptt file) | low | > 76 |
| Pseudomonas sp. DMC3 | 0.63 | GFF4833 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.30 | GFF5060 | | HTH-type transcriptional regulator ArgP | low | > 89 |
| Pseudomonas sp. RS175 | 0.63 | PFR28_03236 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.31 | PFR28_00608 | | HTH-type transcriptional regulator ArgP | low | > 88 |
| Pseudomonas lactucae CFBP13502 | 0.63 | GEMAOFIL_03610 | | tRNA-cytidine(32) 2-sulfurtransferase | 0.31 | GEMAOFIL_04569 | | HTH-type transcriptional regulator ArgP | low | > 93 |
| Pseudomonas simiae WCS417 | 0.63 | PS417_16415 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.32 | PS417_22165 | | LysR family transcriptional regulator | low | > 88 |
| Paraburkholderia sabiae LMG 24235 | 0.63 | QEN71_RS28595 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.29 | QEN71_RS23610 | | LysR family transcriptional regulator ArgP | low | > 153 |
| Pseudomonas putida KT2440 | 0.63 | PP_1641 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.30 | PP_0917 | | Chromosome initiation inhibitor | 0.16 | 71 |
| Pseudomonas sp. BP01 | 0.63 | JOY50_RS23840 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.32 | JOY50_RS14225 | | LysR family transcriptional regulator ArgP | low | > 84 |
| Pseudomonas fluorescens FW300-N2E2 | 0.63 | Pf6N2E2_5711 | | tRNA(Cytosine32)-2-thiocytidine synthetase | 0.31 | Pf6N2E2_2849 | | Chromosome initiation inhibitor | low | > 103 |
| Pseudomonas fluorescens FW300-N2E3 | 0.63 | AO353_02780 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.32 | AO353_03915 | | LysR family transcriptional regulator | low | > 101 |
| Pseudomonas fluorescens GW456-L13 | 0.63 | PfGW456L13_2020 | | tRNA(Cytosine32)-2-thiocytidine synthetase | 0.31 | PfGW456L13_1782 | | Chromosome initiation inhibitor | low | > 87 |
| Pseudomonas fluorescens FW300-N1B4 | 0.62 | Pf1N1B4_3491 | | tRNA(Cytosine32)-2-thiocytidine synthetase | 0.31 | Pf1N1B4_708 | | Chromosome initiation inhibitor | low | > 87 |
| Pseudomonas fluorescens FW300-N2C3 | 0.62 | AO356_19000 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.32 | AO356_04995 | | LysR family transcriptional regulator | low | > 104 |
| Acidovorax sp. GW101-3H11 | 0.62 | Ac3H11_1817 | | tRNA(Cytosine32)-2-thiocytidine synthetase | 0.27 | Ac3H11_3378 | | chromosome replication initiation inhibitor protein | low | > 79 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.62 | H281DRAFT_05824 | | tRNA s(2)C-32 sulfurtransferase | 0.29 | H281DRAFT_04882 | | transcriptional regulator, LysR family | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.62 | Psyr_3705 | | conserved hypothetical protein | 0.34 | Psyr_4057 | | regulatory protein, LysR:LysR, substrate-binding protein | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.62 | Psyr_3705 | | conserved hypothetical protein | 0.34 | Psyr_4057 | | regulatory protein, LysR:LysR, substrate-binding protein | low | > 86 |
| Pseudomonas sp. SVBP6 | 0.62 | COO64_RS07395 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.32 | COO64_RS12100 | | LysR family transcriptional regulator ArgP | low | > 93 |
| Burkholderia phytofirmans PsJN | 0.62 | BPHYT_RS18570 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.28 | BPHYT_RS07440 | | LysR family transcriptional regulator | — | — |
| Pseudomonas fluorescens SBW25-INTG | 0.62 | PFLU_RS18455 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.32 | PFLU_RS23790 | | LysR family transcriptional regulator ArgP | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.62 | PFLU_RS18455 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.32 | PFLU_RS23790 | | LysR family transcriptional regulator ArgP | low | > 109 |
| Paraburkholderia graminis OAS925 | 0.62 | ABIE53_000036 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.29 | ABIE53_001719 | | LysR family transcriptional regulator (chromosome initiation inhibitor) | low | > 113 |
| Ralstonia sp. UNC404CL21Col | 0.61 | ABZR87_RS05700 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.30 | ABZR87_RS14025 | | LysR family transcriptional regulator ArgP | low | > 80 |
| Ralstonia solanacearum PSI07 | 0.61 | RPSI07_RS23130 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.30 | RPSI07_RS03900 | | transcriptional regulator ArgP | low | > 81 |
| Shewanella loihica PV-4 | 0.61 | Shew_1995 | | PP-loop domain-containing protein (RefSeq) | 0.42 | Shew_1844 | | chromosome replication initiation inhibitor protein (RefSeq) | low | > 60 |
| Ralstonia solanacearum UW163 | 0.61 | UW163_RS03335 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.31 | UW163_RS20770 | | transcriptional regulator ArgP | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.61 | RALBFv3_RS10245 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.31 | RALBFv3_RS18360 | | transcriptional regulator ArgP | low | > 76 |
| Erwinia tracheiphila SCR3 | 0.60 | LU632_RS12165 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.45 | LU632_RS05845 | | LysR family transcriptional regulator ArgP | low | > 74 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.60 | GFF1658 | | tRNA(Cytosine32)-2-thiocytidine synthetase | 0.29 | GFF5065 | | Chromosome initiation inhibitor | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.60 | RR42_RS01445 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.28 | RR42_RS31465 | | LysR family transcriptional regulator | low | > 128 |
| Dyella japonica UNC79MFTsu3.2 | 0.60 | ABZR86_RS16485 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.27 | ABZR86_RS10990 | | LysR family transcriptional regulator ArgP | low | > 74 |
| Variovorax sp. SCN45 | 0.59 | GFF7310 | | tRNA-(cytosine32)-2-thiocytidine synthetase TtcA | 0.23 | GFF2318 | | Transcriptional regulator ArgP, LysR family | low | > 127 |
| Variovorax sp. OAS795 | 0.59 | ABID97_RS06505 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.26 | ABID97_RS23875 | | LysR family transcriptional regulator ArgP | low | > 91 |
| Acinetobacter baumannii LAC-4 | 0.55 | RR41_RS04315 | | tRNA 2-thiocytidine(32) synthetase TtcA | 0.31 | RR41_RS09265 | | LysR family transcriptional regulator ArgP | low | > 55 |
| Rhodanobacter sp. FW510-T8 | 0.52 | OKGIIK_13200 | ttcA | tRNA 2-thiocytidine(32) synthetase TtcA | 0.27 | OKGIIK_01770 | | Transcriptional regulator ArgP | low | > 53 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.51 | Xcc-8004.5211.1 | | tRNA(Cytosine32)-2-thiocytidine synthetase | 0.26 | Xcc-8004.1463.1 | | Transcriptional regulator lysR family | low | > 74 |
| Phaeobacter inhibens DSM 17395 | 0.46 | PGA1_c02110 | | tRNA 2-thiocytidine biosynthesis protein TtcA | 0.23 | PGA1_c21740 | | transcriptional regulator, ArgP family | low | > 62 |
| Dinoroseobacter shibae DFL-12 | 0.45 | Dshi_0330 | | PP-loop domain protein (RefSeq) | 0.26 | Dshi_0711 | | transcriptional regulator, LysR family (RefSeq) | low | > 64 |
| Agrobacterium fabrum C58 | 0.45 | Atu1858 | | hypothetical protein | 0.27 | Atu0928 | | transcriptional regulator, LysR family | low | > 89 |
Not shown: 12 genomes with orthologs for CSW01_07180 only; 7 genomes with orthologs for CSW01_02560 only