Conservation of cofitness between CSW01_07180 and CSW01_02560 in Vibrio cholerae E7946 ATCC 55056

74 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_07180 tRNA 2-thiocytidine(32) synthetase TtcA 1.0 CSW01_02560 chromosome initiation inhibitor 0.61 6
Escherichia coli ECRC62 0.77 BNILDI_18020 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.44 BNILDI_09890 argP DNA-binding transcriptional regulator ArgP low > 75
Escherichia coli ECRC101 0.77 MCAODC_16100 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.44 MCAODC_09970 argP DNA-binding transcriptional regulator ArgP low > 88
Escherichia coli HS(pFamp)R (ATCC 700891) 0.77 OHPLBJKB_02337 tRNA-cytidine(32) 2-sulfurtransferase 0.44 OHPLBJKB_00800 HTH-type transcriptional regulator ArgP low > 74
Escherichia coli ECRC99 0.77 KEDOAH_26600 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.44 KEDOAH_08690 argP DNA-binding transcriptional regulator ArgP
Escherichia coli Nissle 1917 0.77 ECOLIN_RS08065 tRNA 2-thiocytidine(32) synthetase TtcA 0.44 ECOLIN_RS16225 DNA-binding transcriptional regulator ArgP
Klebsiella michiganensis M5al 0.77 BWI76_RS12710 tRNA 2-thiocytidine(32) synthetase TtcA 0.46 BWI76_RS23930 transcriptional regulator ArgP low > 92
Escherichia coli BL21 0.77 ECD_01321 tRNA s(2)C32 thioltransferase, iron sulfur cluster protein 0.44 ECD_02747 transcriptional regulator for arginine transport and DNA replication genes; replication initiation inhibitor low > 61
Escherichia coli ECRC102 0.77 NIAGMN_26325 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.44 NIAGMN_17215 argP DNA-binding transcriptional regulator ArgP low > 80
Escherichia coli BW25113 0.77 b1344 ydaO predicted C32 tRNA thiolase (NCBI) 0.44 b2916 argP chromosome replication initiation inhibitor protein (NCBI) low > 76
Escherichia coli ECOR27 0.77 NOLOHH_19870 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.44 NOLOHH_11355 argP DNA-binding transcriptional regulator ArgP low > 76
Enterobacter sp. TBS_079 0.77 MPMX20_02440 tRNA-cytidine(32) 2-sulfurtransferase 0.45 MPMX20_03773 HTH-type transcriptional regulator ArgP low > 85
Pectobacterium carotovorum WPP14 0.76 HER17_RS09605 tRNA 2-thiocytidine(32) synthetase TtcA 0.44 HER17_RS02715 LysR family transcriptional regulator ArgP low > 75
Escherichia coli ECRC100 0.76 OKFHMN_02155 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.44 OKFHMN_19450 argP DNA-binding transcriptional regulator ArgP
Escherichia fergusonii Becca 0.76 EFB2_02583 tRNA-cytidine(32) 2-sulfurtransferase 0.44 EFB2_00987 HTH-type transcriptional regulator ArgP low > 86
Enterobacter asburiae PDN3 0.76 EX28DRAFT_1007 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control 0.45 EX28DRAFT_2967 transcriptional regulator, ArgP family low > 76
Escherichia coli ECOR38 0.76 HEPCGN_26005 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.44 HEPCGN_18750 argP DNA-binding transcriptional regulator ArgP low > 88
Klebsiella pneumoniae MKP103 0.76 KDGMDA_20605 tRNA 2-thiocytidine(32) synthetase TtcA 0.46 KDGMDA_04430 DNA-binding transcriptional regulator ArgP low > 95
Dickeya dadantii 3937 0.76 DDA3937_RS12330 tRNA 2-thiocytidine(32) synthetase TtcA 0.45 DDA3937_RS18490 LysR family transcriptional regulator ArgP low > 74
Escherichia coli ECRC98 0.76 JDDGAC_04715 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.44 JDDGAC_23090 argP DNA-binding transcriptional regulator ArgP low > 87
Dickeya dianthicola ME23 0.76 DZA65_RS12850 tRNA 2-thiocytidine(32) synthetase TtcA 0.46 DZA65_RS19550 LysR family transcriptional regulator ArgP low > 75
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.76 GFF2648 tRNA(Cytosine32)-2-thiocytidine synthetase 0.46 GFF3015 Chromosome initiation inhibitor low > 78
Dickeya dianthicola 67-19 0.76 HGI48_RS12410 tRNA 2-thiocytidine(32) synthetase TtcA 0.46 HGI48_RS18415 LysR family transcriptional regulator ArgP low > 71
Pantoea agglomerans CFBP13505 P0401 0.75 PagCFBP13505_RS06680 tRNA 2-thiocytidine(32) synthetase TtcA 0.45 PagCFBP13505_RS15985 LysR family transcriptional regulator ArgP low > 74
Serratia liquefaciens MT49 0.75 IAI46_13420 tRNA 2-thiocytidine(32) synthetase TtcA 0.45 IAI46_20910 LysR family transcriptional regulator ArgP low > 86
Pantoea sp. MT58 0.75 IAI47_09475 tRNA 2-thiocytidine(32) synthetase TtcA 0.45 IAI47_03715 LysR family transcriptional regulator ArgP low > 76
Erwinia amylovora T8 0.74 OLJFJH_13765 tRNA 2-thiocytidine(32) synthetase TtcA 0.44 OLJFJH_08715 HTH-type transcriptional regulator ArgP low > 58
Rahnella sp. WP5 0.73 EX31_RS06375 tRNA 2-thiocytidine(32) synthetase TtcA 0.46 EX31_RS21460 LysR family transcriptional regulator ArgP low > 89
Alteromonas macleodii MIT1002 0.72 MIT1002_02139 tRNA 2-thiocytidine biosynthesis protein TtcA 0.29 MIT1002_00129 OriC replication inhibitor low > 70
Pseudomonas sp. S08-1 0.64 OH686_05145 tRNA-(cytosine32)-2-thiocytidine synthetase TtcA 0.30 OH686_07195 Transcriptional regulator ArgP, LysR family low > 80
Pseudomonas stutzeri RCH2 0.64 Psest_3033 Predicted ATPase of the PP-loop superfamily implicated in cell cycle control 0.32 Psest_1166 transcriptional regulator, ArgP family low > 67
Shewanella amazonensis SB2B 0.64 Sama_1801 hypothetical protein (RefSeq) 0.40 Sama_2987 chromosome replication initiation inhibitor protein (RefSeq) low > 62
Shewanella sp. ANA-3 0.64 Shewana3_2117 PP-loop domain-containing protein (RefSeq) 0.37 Shewana3_1652 chromosome replication initiation inhibitor protein (RefSeq) low > 73
Pseudomonas aeruginosa PA14 0.64 IKLFDK_05600 tRNA 2-thiocytidine(32) synthetase TtcA 0.34 IKLFDK_02285 HTH-type transcriptional regulator ArgP low > 100
Marinobacter adhaerens HP15 0.64 HP15_2116 PP-loop domain protein 0.30 HP15_868 transcriptional regulator, LysR family low > 73
Pseudomonas segetis P6 0.63 MPMX49_01806 tRNA-cytidine(32) 2-sulfurtransferase 0.34 MPMX49_03758 HTH-type transcriptional regulator ArgP low > 75
Shewanella oneidensis MR-1 0.63 SO2354 conserved hypothetical protein (NCBI ptt file) 0.37 SO2866 iciA chromosome initiation inhibitor (NCBI ptt file) low > 76
Pseudomonas sp. DMC3 0.63 GFF4833 tRNA-cytidine(32) 2-sulfurtransferase 0.30 GFF5060 HTH-type transcriptional regulator ArgP low > 89
Pseudomonas sp. RS175 0.63 PFR28_03236 tRNA-cytidine(32) 2-sulfurtransferase 0.31 PFR28_00608 HTH-type transcriptional regulator ArgP low > 88
Pseudomonas lactucae CFBP13502 0.63 GEMAOFIL_03610 tRNA-cytidine(32) 2-sulfurtransferase 0.31 GEMAOFIL_04569 HTH-type transcriptional regulator ArgP low > 93
Pseudomonas simiae WCS417 0.63 PS417_16415 tRNA 2-thiocytidine biosynthesis protein TtcA 0.32 PS417_22165 LysR family transcriptional regulator low > 88
Paraburkholderia sabiae LMG 24235 0.63 QEN71_RS28595 tRNA 2-thiocytidine(32) synthetase TtcA 0.29 QEN71_RS23610 LysR family transcriptional regulator ArgP low > 153
Pseudomonas putida KT2440 0.63 PP_1641 tRNA 2-thiocytidine biosynthesis protein TtcA 0.30 PP_0917 Chromosome initiation inhibitor 0.16 71
Pseudomonas sp. BP01 0.63 JOY50_RS23840 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.32 JOY50_RS14225 LysR family transcriptional regulator ArgP low > 84
Pseudomonas fluorescens FW300-N2E2 0.63 Pf6N2E2_5711 tRNA(Cytosine32)-2-thiocytidine synthetase 0.31 Pf6N2E2_2849 Chromosome initiation inhibitor low > 103
Pseudomonas fluorescens FW300-N2E3 0.63 AO353_02780 tRNA 2-thiocytidine biosynthesis protein TtcA 0.32 AO353_03915 LysR family transcriptional regulator low > 101
Pseudomonas fluorescens GW456-L13 0.63 PfGW456L13_2020 tRNA(Cytosine32)-2-thiocytidine synthetase 0.31 PfGW456L13_1782 Chromosome initiation inhibitor low > 87
Pseudomonas fluorescens FW300-N1B4 0.62 Pf1N1B4_3491 tRNA(Cytosine32)-2-thiocytidine synthetase 0.31 Pf1N1B4_708 Chromosome initiation inhibitor low > 87
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_19000 tRNA 2-thiocytidine biosynthesis protein TtcA 0.32 AO356_04995 LysR family transcriptional regulator low > 104
Acidovorax sp. GW101-3H11 0.62 Ac3H11_1817 tRNA(Cytosine32)-2-thiocytidine synthetase 0.27 Ac3H11_3378 chromosome replication initiation inhibitor protein low > 79
Paraburkholderia bryophila 376MFSha3.1 0.62 H281DRAFT_05824 tRNA s(2)C-32 sulfurtransferase 0.29 H281DRAFT_04882 transcriptional regulator, LysR family
Pseudomonas syringae pv. syringae B728a ΔmexB 0.62 Psyr_3705 conserved hypothetical protein 0.34 Psyr_4057 regulatory protein, LysR:LysR, substrate-binding protein low > 86
Pseudomonas syringae pv. syringae B728a 0.62 Psyr_3705 conserved hypothetical protein 0.34 Psyr_4057 regulatory protein, LysR:LysR, substrate-binding protein low > 86
Pseudomonas sp. SVBP6 0.62 COO64_RS07395 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.32 COO64_RS12100 LysR family transcriptional regulator ArgP low > 93
Burkholderia phytofirmans PsJN 0.62 BPHYT_RS18570 tRNA 2-thiocytidine biosynthesis protein TtcA 0.28 BPHYT_RS07440 LysR family transcriptional regulator
Pseudomonas fluorescens SBW25-INTG 0.62 PFLU_RS18455 tRNA 2-thiocytidine(32) synthetase TtcA 0.32 PFLU_RS23790 LysR family transcriptional regulator ArgP low > 109
Pseudomonas fluorescens SBW25 0.62 PFLU_RS18455 tRNA 2-thiocytidine(32) synthetase TtcA 0.32 PFLU_RS23790 LysR family transcriptional regulator ArgP low > 109
Paraburkholderia graminis OAS925 0.62 ABIE53_000036 tRNA 2-thiocytidine biosynthesis protein TtcA 0.29 ABIE53_001719 LysR family transcriptional regulator (chromosome initiation inhibitor) low > 113
Ralstonia sp. UNC404CL21Col 0.61 ABZR87_RS05700 tRNA 2-thiocytidine(32) synthetase TtcA 0.30 ABZR87_RS14025 LysR family transcriptional regulator ArgP low > 80
Ralstonia solanacearum PSI07 0.61 RPSI07_RS23130 tRNA 2-thiocytidine(32) synthetase TtcA 0.30 RPSI07_RS03900 transcriptional regulator ArgP low > 81
Shewanella loihica PV-4 0.61 Shew_1995 PP-loop domain-containing protein (RefSeq) 0.42 Shew_1844 chromosome replication initiation inhibitor protein (RefSeq) low > 60
Ralstonia solanacearum UW163 0.61 UW163_RS03335 tRNA 2-thiocytidine(32) synthetase TtcA 0.31 UW163_RS20770 transcriptional regulator ArgP
Ralstonia solanacearum IBSBF1503 0.61 RALBFv3_RS10245 tRNA 2-thiocytidine(32) synthetase TtcA 0.31 RALBFv3_RS18360 transcriptional regulator ArgP low > 76
Erwinia tracheiphila SCR3 0.60 LU632_RS12165 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.45 LU632_RS05845 LysR family transcriptional regulator ArgP low > 74
Hydrogenophaga sp. GW460-11-11-14-LB1 0.60 GFF1658 tRNA(Cytosine32)-2-thiocytidine synthetase 0.29 GFF5065 Chromosome initiation inhibitor
Cupriavidus basilensis FW507-4G11 0.60 RR42_RS01445 tRNA 2-thiocytidine biosynthesis protein TtcA 0.28 RR42_RS31465 LysR family transcriptional regulator low > 128
Dyella japonica UNC79MFTsu3.2 0.60 ABZR86_RS16485 tRNA 2-thiocytidine(32) synthetase TtcA 0.27 ABZR86_RS10990 LysR family transcriptional regulator ArgP low > 74
Variovorax sp. SCN45 0.59 GFF7310 tRNA-(cytosine32)-2-thiocytidine synthetase TtcA 0.23 GFF2318 Transcriptional regulator ArgP, LysR family low > 127
Variovorax sp. OAS795 0.59 ABID97_RS06505 tRNA 2-thiocytidine(32) synthetase TtcA 0.26 ABID97_RS23875 LysR family transcriptional regulator ArgP low > 91
Acinetobacter baumannii LAC-4 0.55 RR41_RS04315 tRNA 2-thiocytidine(32) synthetase TtcA 0.31 RR41_RS09265 LysR family transcriptional regulator ArgP low > 55
Rhodanobacter sp. FW510-T8 0.52 OKGIIK_13200 ttcA tRNA 2-thiocytidine(32) synthetase TtcA 0.27 OKGIIK_01770 Transcriptional regulator ArgP low > 53
Xanthomonas campestris pv. campestris strain 8004 0.51 Xcc-8004.5211.1 tRNA(Cytosine32)-2-thiocytidine synthetase 0.26 Xcc-8004.1463.1 Transcriptional regulator lysR family low > 74
Phaeobacter inhibens DSM 17395 0.46 PGA1_c02110 tRNA 2-thiocytidine biosynthesis protein TtcA 0.23 PGA1_c21740 transcriptional regulator, ArgP family low > 62
Dinoroseobacter shibae DFL-12 0.45 Dshi_0330 PP-loop domain protein (RefSeq) 0.26 Dshi_0711 transcriptional regulator, LysR family (RefSeq) low > 64
Agrobacterium fabrum C58 0.45 Atu1858 hypothetical protein 0.27 Atu0928 transcriptional regulator, LysR family low > 89

Not shown: 12 genomes with orthologs for CSW01_07180 only; 7 genomes with orthologs for CSW01_02560 only