Conservation of cofitness between CSW01_05825 and CSW01_00170 in Vibrio cholerae E7946 ATCC 55056

70 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_05825 transcriptional regulator HexR 1.0 CSW01_00170 thiol:disulfide interchange protein DsbA 0.85 1
Shewanella loihica PV-4 0.78 Shew_2049 DNA-binding transcriptional regulator HexR (RefSeq) 0.38 Shew_0265 DSBA oxidoreductase (RefSeq) low > 60
Serratia liquefaciens MT49 0.78 IAI46_14580 MurR/RpiR family transcriptional regulator 0.36 IAI46_24995 thiol:disulfide interchange protein DsbA low > 87
Shewanella oneidensis MR-1 0.77 SO2490 transcriptional regulator, RpiR family (NCBI ptt file) 0.36 SO0333 dsbA thiol:disulfide interchange protein DsbA (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.77 Shewana3_2152 DNA-binding transcriptional regulator HexR (RefSeq) 0.35 Shewana3_3838 DSBA oxidoreductase (RefSeq) low > 73
Pectobacterium carotovorum WPP14 0.77 HER17_RS11785 MurR/RpiR family transcriptional regulator 0.37 HER17_RS21475 thiol:disulfide interchange protein DsbA low > 75
Shewanella amazonensis SB2B 0.77 Sama_1813 DNA-binding transcriptional regulator HexR (RefSeq) 0.36 Sama_3321 thiol:disulfide interchange protein DsbA (RefSeq) low > 62
Rahnella sp. WP5 0.76 EX31_RS10635 MurR/RpiR family transcriptional regulator 0.36 EX31_RS15910 thiol:disulfide interchange protein DsbA low > 89
Dickeya dianthicola 67-19 0.75 HGI48_RS10160 MurR/RpiR family transcriptional regulator 0.37 HGI48_RS21265 thiol:disulfide interchange protein DsbA low > 71
Dickeya dianthicola ME23 0.75 DZA65_RS10575 MurR/RpiR family transcriptional regulator 0.36 DZA65_RS22240 thiol:disulfide interchange protein DsbA low > 75
Dickeya dadantii 3937 0.75 DDA3937_RS10130 MurR/RpiR family transcriptional regulator 0.37 DDA3937_RS00100 thiol:disulfide interchange protein DsbA low > 74
Enterobacter asburiae PDN3 0.74 EX28DRAFT_0703 transcriptional regulator, RpiR family 0.37 EX28DRAFT_4341 Protein-disulfide isomerase low > 76
Enterobacter sp. TBS_079 0.74 MPMX20_02758 HTH-type transcriptional regulator HexR 0.38 MPMX20_04603 Thiol:disulfide interchange protein DsbA — —
Escherichia coli ECRC99 0.73 KEDOAH_01780 hexR DNA-binding transcriptional regulator HexR 0.38 KEDOAH_13980 dsbA thiol:disulfide interchange protein DsbA — —
Escherichia coli ECRC100 0.73 OKFHMN_26325 hexR DNA-binding transcriptional regulator HexR 0.38 OKFHMN_14170 dsbA thiol:disulfide interchange protein DsbA low > 79
Escherichia coli ECRC102 0.73 NIAGMN_01735 hexR DNA-binding transcriptional regulator HexR 0.38 NIAGMN_11925 dsbA thiol:disulfide interchange protein DsbA low > 80
Escherichia coli Nissle 1917 0.73 ECOLIN_RS10325 DNA-binding transcriptional regulator HexR 0.38 ECOLIN_RS22250 thiol:disulfide interchange protein DsbA low > 55
Escherichia coli ECOR27 0.73 NOLOHH_16840 hexR DNA-binding transcriptional regulator HexR 0.38 NOLOHH_06300 dsbA thiol:disulfide interchange protein DsbA low > 76
Escherichia coli ECOR38 0.73 HEPCGN_04730 hexR DNA-binding transcriptional regulator HexR 0.38 HEPCGN_12805 dsbA thiol:disulfide interchange protein DsbA low > 88
Escherichia coli ECRC101 0.73 MCAODC_19080 hexR DNA-binding transcriptional regulator HexR 0.38 MCAODC_04670 dsbA thiol:disulfide interchange protein DsbA — —
Escherichia coli ECRC98 0.73 JDDGAC_00900 hexR DNA-binding transcriptional regulator HexR 0.38 JDDGAC_17795 dsbA thiol:disulfide interchange protein DsbA low > 87
Escherichia coli ECRC62 0.73 BNILDI_15635 hexR DNA-binding transcriptional regulator HexR 0.38 BNILDI_05230 dsbA thiol:disulfide interchange protein DsbA low > 75
Escherichia fergusonii Becca 0.73 EFB2_02089 HTH-type transcriptional regulator HexR 0.38 EFB2_04757 Thiol:disulfide interchange protein DsbA low > 86
Escherichia coli BL21 0.73 ECD_01824 putative DNA-binding transcriptional regulator 0.38 ECD_03746 periplasmic protein disulfide isomerase I low > 61
Escherichia coli BW25113 0.73 b1853 yebK predicted DNA-binding transcriptional regulator (NCBI) 0.38 b3860 dsbA periplasmic protein disulfide isomerase I (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.73 OHPLBJKB_01875 HTH-type transcriptional regulator HexR 0.38 OHPLBJKB_04193 Thiol:disulfide interchange protein DsbA low > 74
Alteromonas macleodii MIT1002 0.73 MIT1002_02408 putative HTH-type transcriptional regulator YbbH 0.34 MIT1002_00714 Thiol:disulfide interchange protein DsbA precursor — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.72 GFF1632 Phosphogluconate repressor HexR, RpiR family 0.36 GFF2213 Periplasmic thiol:disulfide interchange protein DsbA low > 78
Klebsiella pneumoniae MKP103 0.72 KDGMDA_25375 transcriptional regulator HexR 0.35 KDGMDA_08960 thiol:disulfide interchange protein DsbA — —
Klebsiella michiganensis M5al 0.72 BWI76_RS18110 transcriptional regulator HexR 0.35 BWI76_RS00345 protein disulfide oxidoreductase DsbA low > 92
Erwinia tracheiphila HP pepo 2.2 0.64 IJEDHG_22185 transcriptional regulator HexR 0.36 IJEDHG_10985 dsbA thiol:disulfide interchange protein DsbA low > 61
Erwinia tracheiphila SCR3 0.64 LU632_RS13365 MurR/RpiR family transcriptional regulator 0.36 LU632_RS23875 dsbA thiol:disulfide interchange protein DsbA low > 73
Pantoea sp. MT58 0.63 IAI47_08490 MurR/RpiR family transcriptional regulator 0.35 IAI47_00425 thiol:disulfide interchange protein DsbA — —
Pantoea agglomerans CFBP13505 P0401 0.61 PagCFBP13505_RS02370 transcriptional regulator HexR 0.35 PagCFBP13505_RS18930 thiol:disulfide interchange protein DsbA — —
Pseudomonas sp. S08-1 0.58 OH686_02440 Phosphogluconate repressor HexR, RpiR family 0.21 OH686_12195 Periplasmic thiol:disulfide interchange protein DsbA low > 80
Pseudomonas sp. SVBP6 0.58 COO64_RS04585 hexR DNA-binding transcriptional regulator HexR 0.22 COO64_RS02495 dsbA thiol:disulfide interchange protein DsbA low > 93
Pseudomonas sp. DMC3 0.58 GFF5141 HTH-type transcriptional regulator HexR 0.19 GFF627 Thiol:disulfide interchange protein DsbA — —
Pseudomonas fluorescens FW300-N2E2 0.57 Pf6N2E2_2886 Phosphogluconate repressor HexR, RpiR family 0.22 Pf6N2E2_4158 Periplasmic thiol:disulfide interchange protein DsbA — —
Pseudomonas fluorescens FW300-N2C3 0.57 AO356_05165 transcriptional regulator 0.21 AO356_11445 thiol:disulfide interchange protein — —
Pseudomonas sp. RS175 0.57 PFR28_00572 HTH-type transcriptional regulator HexR 0.20 PFR28_04628 Thiol:disulfide interchange protein DsbA low > 88
Pseudomonas fluorescens FW300-N1B4 0.57 Pf1N1B4_590 Phosphogluconate repressor HexR, RpiR family 0.20 Pf1N1B4_1879 Periplasmic thiol:disulfide interchange protein DsbA — —
Pseudomonas stutzeri RCH2 0.57 Psest_0851 Transcriptional regulators 0.19 Psest_0186 Protein-disulfide isomerase low > 67
Pseudomonas fluorescens FW300-N2E3 0.57 AO353_03365 transcriptional regulator 0.21 AO353_10950 thiol:disulfide interchange protein low > 101
Pseudomonas orientalis W4I3 0.57 QF045_RS24250 MurR/RpiR family transcriptional regulator 0.21 QF045_RS03370 thiol:disulfide interchange protein DsbA low > 93
Pseudomonas simiae WCS417 0.57 PS417_22115 transcriptional regulator 0.20 PS417_00425 thiol:disulfide interchange protein — —
Pseudomonas putida KT2440 0.57 PP_1021 DNA-binding transcriptional regulator 0.21 PP_0127 Thiol:disulfide interchange protein low > 96
Pseudomonas fluorescens SBW25-INTG 0.57 PFLU_RS23730 MurR/RpiR family transcriptional regulator 0.20 PFLU_RS00415 thiol:disulfide interchange protein DsbA/DsbL low > 109
Pseudomonas sp. BP01 0.57 JOY50_RS11445 hexR DNA-binding transcriptional regulator HexR 0.21 JOY50_RS21090 dsbA thiol:disulfide interchange protein DsbA low > 84
Pseudomonas fluorescens SBW25 0.57 PFLU_RS23730 MurR/RpiR family transcriptional regulator 0.20 PFLU_RS00415 thiol:disulfide interchange protein DsbA/DsbL low > 109
Pseudomonas lactucae CFBP13502 0.57 GEMAOFIL_04559 HTH-type transcriptional regulator HexR 0.20 GEMAOFIL_00288 Thiol:disulfide interchange protein DsbA — —
Pseudomonas syringae pv. syringae B728a 0.56 Psyr_1119 Helix-turn-helix protein RpiR:Sugar isomerase (SIS) 0.18 Psyr_0268 DSBA oxidoreductase low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.56 Psyr_1119 Helix-turn-helix protein RpiR:Sugar isomerase (SIS) 0.18 Psyr_0268 DSBA oxidoreductase — —
Marinobacter adhaerens HP15 0.55 HP15_2180 transcriptional regulator, RpiR family protein 0.22 HP15_3325 DSBA oxidoreductase low > 73
Pseudomonas aeruginosa PA14 0.55 IKLFDK_16180 HTH-type transcriptional regulator HexR 0.21 IKLFDK_25970 thiol:disulfide interchange protein DsbA low > 98
Pseudomonas aeruginosa PUPa3 0.55 DQ20_RS34520 MurR/RpiR family transcriptional regulator 0.21 DQ20_RS58175 dsbA;inference=COORDINATES thiol:disulfide interchange protein DsbA — —
Pseudomonas aeruginosa MRSN321 0.55 DY961_RS01015 MurR/RpiR family transcriptional regulator 0.21 DY961_RS25745 dsbA;inference=COORDINATES thiol:disulfide interchange protein DsbA — —
Castellaniella sp019104865 MT123 0.39 ABCV34_RS08655 SIS domain-containing protein 0.16 ABCV34_RS12390 thiol:disulfide interchange protein DsbA/DsbL low > 48
Paraburkholderia graminis OAS925 0.35 ABIE53_003518 RpiR family carbohydrate utilization transcriptional regulator 0.21 ABIE53_000598 thiol:disulfide interchange protein DsbA 0.34 72
Burkholderia phytofirmans PsJN 0.34 BPHYT_RS16740 transcriptional regulator 0.19 BPHYT_RS02280 DSBA oxidoreductase — —
Acidovorax sp. GW101-3H11 0.34 Ac3H11_2055 Probable transcriptional regulator 0.20 Ac3H11_724 Periplasmic thiol:disulfide interchange protein DsbA — —
Cupriavidus basilensis FW507-4G11 0.34 RR42_RS06120 transcriptional regulator 0.21 RR42_RS00835 DSBA oxidoreductase low > 128
Paraburkholderia bryophila 376MFSha3.1 0.33 H281DRAFT_04279 transcriptional regulator, RpiR family 0.19 H281DRAFT_02081 thiol:disulfide interchange protein DsbA — —
Herbaspirillum seropedicae SmR1 0.32 HSERO_RS05505 transcriptional regulator 0.18 HSERO_RS21760 DSBA oxidoreductase low > 78
Paraburkholderia sabiae LMG 24235 0.30 QEN71_RS26925 MurR/RpiR family transcriptional regulator 0.20 QEN71_RS01165 thiol:disulfide interchange protein DsbA/DsbL low > 153
Ralstonia solanacearum GMI1000 0.23 RS_RS22855 MurR/RpiR family transcriptional regulator 0.18 RS_RS21435 thiol:disulfide interchange protein DsbA/DsbL low > 80
Ralstonia sp. UNC404CL21Col 0.22 ABZR87_RS03145 MurR/RpiR family transcriptional regulator 0.14 ABZR87_RS06350 thiol:disulfide interchange protein DsbA/DsbL low > 80
Ralstonia solanacearum IBSBF1503 0.22 RALBFv3_RS18180 MurR/RpiR family transcriptional regulator 0.13 RALBFv3_RS10560 thiol:disulfide interchange protein DsbA/DsbL low > 76
Ralstonia solanacearum PSI07 0.22 RPSI07_RS05455 MurR/RpiR family transcriptional regulator 0.13 RPSI07_RS22755 thiol:disulfide interchange protein DsbA/DsbL low > 81
Ralstonia solanacearum UW163 0.22 UW163_RS20950 MurR/RpiR family transcriptional regulator 0.13 UW163_RS03020 thiol:disulfide interchange protein DsbA/DsbL — —
Variovorax sp. OAS795 0.20 ABID97_RS22860 MurR/RpiR family transcriptional regulator 0.23 ABID97_RS04765 thiol:disulfide interchange protein DsbA/DsbL low > 91
Variovorax sp. SCN45 0.20 GFF6715 Transcriptional regulator of RpiR family in catabolic operon 0.24 GFF6293 Periplasmic thiol:disulfide interchange protein DsbA low > 127

Not shown: 9 genomes with orthologs for CSW01_05825 only; 8 genomes with orthologs for CSW01_00170 only