| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
|---|
| Klebsiella michiganensis M5al | 1.0 | BWI76_RS19375 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 1.0 | BWI76_RS23090 | | cobyrinic acid a,c-diamide synthase | 0.24 | 13 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.90 | GFF3834 | | Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) | 0.80 | GFF3950 | | Cobyrinic acid A,C-diamide synthase | low | > 78 |
| Paraburkholderia sabiae LMG 24235 | 0.54 | QEN71_RS06305 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.23 | QEN71_RS08690 | | cobyrinate a,c-diamide synthase | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.54 | H281DRAFT_00587 | | hydroxymethylpyrimidine kinase /phosphomethylpyrimidine kinase | 0.21 | H281DRAFT_06530 | | hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) (EC 6.3.5.9)/cobyrinate a,c-diamide synthase (EC 6.3.5.11) | — | — |
| Burkholderia phytofirmans PsJN | 0.52 | BPHYT_RS12250 | | phosphomethylpyrimidine kinase | 0.24 | BPHYT_RS24820 | | cobyrinic acid a,c-diamide synthase | — | — |
| Paraburkholderia graminis OAS925 | 0.50 | ABIE53_002529 | | hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.22 | ABIE53_006185 | | cobyrinic acid a,c-diamide synthase | — | — |
| Rhizobium sp. OAE497 | 0.50 | ABIE40_RS25930 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.24 | ABIE40_RS11105 | | cobyrinate a,c-diamide synthase | 0.44 | 58 |
| Rhodopseudomonas palustris CGA009 | 0.48 | TX73_020570 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.23 | TX73_010735 | | cobyrinate a,c-diamide synthase | — | — |
| Agrobacterium fabrum C58 | 0.46 | Atu3290 | | phosphomethylpyrimidine kinase | 0.26 | Atu2793 | | cobyrinic acid a,c-diamide synthase | low | > 89 |
| Bosea sp. OAE506 | 0.44 | ABIE41_RS21620 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.27 | ABIE41_RS01835 | | cobyrinate a,c-diamide synthase | — | — |
| Parabacteroides merdae CL09T00C40 | 0.43 | HMPREF1078_RS03470 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.29 | HMPREF1078_RS09710 | | cobyrinate a,c-diamide synthase | low | > 61 |
| Sinorhizobium meliloti 1021 | 0.42 | SM_b20962 | | phoshomethylpyrimidine kinase | 0.21 | SMc04282 | | cobyrinic acid a,c-diamide synthase | — | — |
| Phocaeicola vulgatus CL09T03C04 | 0.39 | HMPREF1058_RS06820 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.27 | HMPREF1058_RS01405 | | cobyrinate a,c-diamide synthase | low | > 67 |
| Phocaeicola dorei CL03T12C01 | 0.39 | ABI39_RS20615 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.26 | ABI39_RS15650 | | cobyrinate a,c-diamide synthase | low | > 72 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.38 | GFF249 | | Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) | 0.24 | GFF3977 | | Cobyrinic acid A,C-diamide synthase | low | > 90 |
| Dinoroseobacter shibae DFL-12 | 0.38 | Dshi_0915 | | phosphomethylpyrimidine kinase (RefSeq) | 0.26 | Dshi_1693 | | cobyrinic acid a,c-diamide synthase (RefSeq) | — | — |
| Bacteroides stercoris CC31F | 0.38 | HMPREF1181_RS14705 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.22 | HMPREF1181_RS10540 | | cobyrinate a,c-diamide synthase | low | > 56 |
| Rhodospirillum rubrum S1H | 0.37 | Rru_A1102 | | Phosphomethylpyrimidine kinase (NCBI) | 0.29 | Rru_A3359 | | Cobyrinic acid a,c-diamide synthase CbiA (NCBI) | — | — |
| Azospirillum brasilense Sp245 | 0.36 | AZOBR_RS07045 | | phosphomethylpyrimidine kinase | 0.30 | AZOBR_RS16735 | | cobyrinic acid a c-diamide synthase | — | — |
| Ralstonia solanacearum GMI1000 | 0.36 | RS_RS00495 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.22 | RS_RS20060 | | cobyrinate a,c-diamide synthase | — | — |
| Ralstonia solanacearum IBSBF1503 | 0.35 | RALBFv3_RS09905 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.25 | RALBFv3_RS20545 | | cobyrinate a,c-diamide synthase | — | — |
| Ralstonia solanacearum UW163 | 0.35 | UW163_RS03675 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.25 | UW163_RS18630 | | cobyrinate a,c-diamide synthase | — | — |
| Ralstonia solanacearum PSI07 | 0.35 | RPSI07_RS23455 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.25 | RPSI07_RS02195 | | cobyrinate a,c-diamide synthase | — | — |
| Variovorax sp. OAS795 | 0.35 | ABID97_RS15330 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.23 | ABID97_RS17420 | | cobyrinate a,c-diamide synthase | — | — |
| Azospirillum sp. SherDot2 | 0.34 | MPMX19_06182 | | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.24 | MPMX19_05562 | | Hydrogenobyrinate a,c-diamide synthase | — | — |
| Acidovorax sp. GW101-3H11 | 0.33 | Ac3H11_1063 | | Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) | 0.24 | Ac3H11_986 | | Cobyrinic acid A,C-diamide synthase | — | — |
| Cupriavidus basilensis FW507-4G11 | 0.32 | RR42_RS01370 | | phosphomethylpyrimidine kinase | 0.24 | RR42_RS35070 | | cobyrinic acid a,c-diamide synthase | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.30 | Xcc-8004.3091.1 | | hypothetical protein | 0.22 | Xcc-8004.1394.1 | | Cobyrinic acid A,C-diamide synthase | low | > 74 |
| Fusobacterium nucleatum SB010 | 0.30 | HUW76_10300 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.33 | HUW76_05255 | | cobyrinate a,c-diamide synthase | low | > 35 |
| Magnetospirillum magneticum AMB-1 | 0.30 | AMB_RS16155 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.25 | AMB_RS18335 | | cobyrinate a,c-diamide synthase | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.29 | ABZR86_RS00760 | | bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase | 0.23 | ABZR86_RS10915 | | cobyrinate a,c-diamide synthase | — | — |
| Desulfovibrio vulgaris Miyazaki F | 0.28 | DvMF_1376 | | phosphomethylpyrimidine kinase (RefSeq) | 0.29 | DvMF_2254 | | cobyrinic acid a,c-diamide synthase (RefSeq) | — | — |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.28 | DVU0931 | thiD | phosphomethylpyrimidine kinase (TIGR) | 0.27 | DVU0405 | cobB-1 | cobyrinic acid a,c-diamide synthase (TIGR) | — | — |
| Dechlorosoma suillum PS | 0.24 | Dsui_0662 | | phosphomethylpyrimidine kinase | 0.20 | Dsui_0533 | | cobyrinic acid a,c-diamide synthase | — | — |
| Mycobacterium tuberculosis H37Rv | 0.24 | Rv0422c | | Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) | 0.25 | Rv2848c | | Probable cobyrinic acid A,C-diamide synthase CobB | — | — |
| Pseudomonas fluorescens SBW25 | 0.24 | PFLU_RS26530 | | hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.24 | PFLU_RS22025 | | cobyrinate a,c-diamide synthase | low | > 109 |
| Pseudomonas fluorescens SBW25-INTG | 0.24 | PFLU_RS26530 | | hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.24 | PFLU_RS22025 | | cobyrinate a,c-diamide synthase | 0.38 | 21 |
| Pseudomonas simiae WCS417 | 0.23 | PS417_24600 | | hydrogenase | 0.24 | PS417_20060 | | cobyrinic acid a,c-diamide synthase | low | > 88 |
| Synechococcus elongatus PCC 7942 | 0.23 | Synpcc7942_2379 | thiD | phosphomethylpyrimidine kinase | 0.29 | Synpcc7942_1855 | cobB | cobyrinic acid a,c-diamide synthase | — | — |
| Pseudomonas putida KT2440 | 0.22 | PP_4782 | | Phosphomethylpyrimidine kinase | 0.25 | PP_1673 | | cobyrinate a,c-diamide synthase | low | > 96 |
| Pseudomonas fluorescens GW456-L13 | 0.22 | PfGW456L13_1385 | | Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) | 0.23 | PfGW456L13_4242 | | Cobyrinic acid A,C-diamide synthase | low | > 87 |
| Pseudomonas fluorescens FW300-N2E3 | 0.22 | AO353_06350 | | hydrogenase | 0.24 | AO353_02635 | | cobyrinic acid a,c-diamide synthase | low | > 101 |
| Pseudomonas fluorescens FW300-N2C3 | 0.22 | AO356_15435 | | hydrogenase | 0.24 | AO356_19140 | | cobyrinic acid a,c-diamide synthase | low | > 104 |
| Pseudomonas stutzeri RCH2 | 0.21 | Psest_0537 | | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.23 | Psest_3013 | | cobyrinic acid a,c-diamide synthase | low | > 67 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.21 | Psyr_4340 | | phosphomethylpyrimidine kinase, putative | 0.24 | Psyr_3680 | | hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) / cobyrinate a,c-diamide synthase | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.21 | Psyr_4340 | | phosphomethylpyrimidine kinase, putative | 0.24 | Psyr_3680 | | hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) / cobyrinate a,c-diamide synthase | low | > 86 |
| Pseudomonas sp. RS175 | 0.20 | PFR28_03843 | | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase | 0.24 | PFR28_03208 | | Cobyrinate a,c-diamide synthase | low | > 88 |
| Pseudomonas fluorescens FW300-N1B4 | 0.18 | Pf1N1B4_2718 | | Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) | 0.24 | Pf1N1B4_3707 | | Cobyrinic acid A,C-diamide synthase | low | > 87 |
| Pseudomonas fluorescens FW300-N2E2 | 0.18 | Pf6N2E2_5024 | | Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) | 0.25 | Pf6N2E2_5738 | | Cobyrinic acid A,C-diamide synthase | low | > 103 |
| Herbaspirillum seropedicae SmR1 | 0.18 | HSERO_RS02135 | | phosphomethylpyrimidine kinase | 0.23 | HSERO_RS13255 | | cobyrinic acid a,c-diamide synthase | low | > 78 |
| Phaeobacter inhibens DSM 17395 | 0.17 | PGA1_c09030 | | phosphomethylpyrimidine kinase ThiD | 0.25 | PGA1_c08080 | | putative cobyrinic acid A,C-diamide synthase CobB | — | — |
Not shown: 38 genomes with orthologs for BWI76_RS19375 only; 5 genomes with orthologs for BWI76_RS23090 only