| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_12235 | | bifunctional metallophosphatase/5'-nucleotidase | insig. | 100 | 100 |
| o | Serratia liquefaciens MT49 | IAI46_24200 | | 5'-nucleotidase C-terminal domain-containing protein | cofit | 67 | 100 |
| o | Pectobacterium carotovorum WPP14 | HER17_RS21310 | | 5'-nucleotidase C-terminal domain-containing protein | insig. | 68 | 97 |
| o | Bacteroides thetaiotaomicron VPI-5482 | BT1236 | | 2',3'-cyclic-nucleotide 2'-phosphodiesterase precursor (NCBI ptt file) | insig. | 28 | 84 |
| | Dinoroseobacter shibae DFL-12 | Dshi_2189 | | 5'-Nucleotidase domain protein (RefSeq) | sig. | 28 | 86 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_00529 | | 5'-nucleotidase, C-terminal domain protein | insig. | 28 | 84 |
| o | Phocaeicola dorei CL03T12C01 | ABI39_RS13925 | | bifunctional metallophosphatase/5'-nucleotidase | cofit | 26 | 87 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS17715 | | bifunctional metallophosphatase/5'-nucleotidase | sig. | 27 | 87 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c18140 | | 2',3'-cyclic-nucleotide 2'-phosphodiesterase CpdB | insig. | 26 | 85 |
| | Klebsiella michiganensis M5al | BWI76_RS02730 | | 2',3'-cyclic-nucleotide 2'-phosphodiesterase | insig. | 27 | 77 |
| | Escherichia coli ECRC98 | JDDGAC_15685 | cpdB | 2',3'-cyclic-nucleotide 2'-phosphodiesterase | insig. | 26 | 77 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03820 | | '2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase' transl_table=11 | insig. | 25 | 87 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS04030 | | bifunctional metallophosphatase/5'-nucleotidase | insig. | 26 | 78 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS24475 | | 2',3'-cyclic-nucleotide 2'-phosphodiesterase | insig. | 25 | 91 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF866 | | '2',3'-cyclic-nucleotide 2'-phosphodiesterase (EC 3.1.4.16)' transl_table=11 | insig. | 26 | 77 |
| | Escherichia coli ECRC100 | OKFHMN_12045 | cpdB | 2',3'-cyclic-nucleotide 2'-phosphodiesterase | insig. | 26 | 77 |
| | Escherichia coli ECRC101 | MCAODC_02560 | cpdB | 2',3'-cyclic-nucleotide 2'-phosphodiesterase | insig. | 26 | 77 |
| | Escherichia coli ECRC102 | NIAGMN_09895 | cpdB | 2',3'-cyclic-nucleotide 2'-phosphodiesterase | insig. | 26 | 77 |
| | Escherichia coli ECRC99 | KEDOAH_16110 | cpdB | 2',3'-cyclic-nucleotide 2'-phosphodiesterase | no data | 26 | 77 |
| | Escherichia coli ECOR27 | NOLOHH_04305 | cpdB | 2',3'-cyclic-nucleotide 2'-phosphodiesterase | insig. | 25 | 87 |
| | Escherichia coli ECRC62 | BNILDI_07215 | cpdB | 2',3'-cyclic-nucleotide 2'-phosphodiesterase | cofit | 25 | 87 |
| | Escherichia fergusonii Becca | EFB2_04315 | | 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 25 | 87 |
| | Escherichia coli BW25113 | b4213 | cpdB | bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein (NCBI) | insig. | 25 | 87 |
| | Escherichia coli ECOR38 | HEPCGN_10240 | cpdB | 2',3'-cyclic-nucleotide 2'-phosphodiesterase | insig. | 25 | 87 |
| | Escherichia coli BL21 | ECD_04085 | | 2':3'-cyclic-nucleotide 2'-phosphodiesterase | insig. | 25 | 87 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_12970 | | 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 26 | 76 |
| | Sinorhizobium meliloti 1021 | SMc04449 | | bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic protein | insig. | 28 | 83 |
| | Rhizobium sp. OAE497 | ABIE40_RS08240 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 26 | 86 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_11215 | | bifunctional 2' 3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 26 | 77 |
| | Dickeya dianthicola 67-19 | HGI48_RS17240 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 24 | 77 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS10415 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 24 | 84 |
| | Dickeya dianthicola ME23 | DZA65_RS18330 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 24 | 77 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS10055 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | cofit | 25 | 87 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_3400 | | 2',3'-cyclic-nucleotide 2'-phosphodiesterase | insig. | 28 | 77 |
| | Enterobacter sp. TBS_079 | MPMX20_00491 | | 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 27 | 77 |
| | Serratia liquefaciens MT49 | IAI46_01740 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 25 | 77 |
| | Shewanella loihica PV-4 | Shew_2162 | cpdB | bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein (RefSeq) | insig. | 25 | 85 |
| | Erwinia amylovora T8 | OLJFJH_02415 | | bifunctional 2' 3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 25 | 77 |
| | Pantoea sp. MT58 | IAI47_02690 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 25 | 76 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS11285 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 25 | 76 |
| | Agrobacterium fabrum C58 | Atu1210 | | putative 2,3-cyclic nucleotide 2-phosphodiesterase/3-nucleotidase | insig. | 25 | 83 |
| | Shewanella amazonensis SB2B | Sama_1563 | cpdB | bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein (RefSeq) | insig. | 25 | 74 |
| | Dickeya dadantii 3937 | DDA3937_RS17185 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 24 | 73 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_13510 | ushA | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 24 | 87 |
| | Pantoea agglomerans CFBP13505 P0401 | PagCFBP13505_RS10775 | | bifunctional UDP-sugar hydrolase/5'-nucleotidase | cofit | 25 | 76 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF2328 | | '5'-nucleotidase (EC 3.1.3.5)' transl_table=11 | insig. | 26 | 77 |
| | Rahnella sp. WP5 | EX31_RS08725 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 25 | 77 |
| | Pectobacterium carotovorum WPP14 | HER17_RS03950 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | cofit | 23 | 83 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF1113 | | '5'-nucleotidase (EC 3.1.3.5)' transl_table=11 | insig. | 25 | 77 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS03215 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 24 | 88 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3791 | | 2',3'-cyclic-nucleotide 2'-phosphodiesterase (EC 3.1.4.16) | insig. | 26 | 74 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS16000 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 24 | 83 |
| | Shewanella oneidensis MR-1 | SO3565 | cpdB | 2',3'-cyclic-nucleotide 2'-phosphodiesterase (NCBI ptt file) | insig. | 25 | 70 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS22755 | | bifunctional UDP-sugar hydrolase/5'-nucleotidase | insig. | 26 | 77 |
| | Escherichia fergusonii Becca | EFB2_04673 | | Trifunctional nucleotide phosphoesterase protein YfkN | insig. | 26 | 77 |
| | Pantoea sp. MT58 | IAI47_14425 | | bifunctional UDP-sugar hydrolase/5'-nucleotidase | insig. | 25 | 76 |
| | Shewanella sp. ANA-3 | Shewana3_1585 | cpdB | bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein (RefSeq) | insig. | 24 | 70 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_09310 | | multifunctional 2' 3'-cyclic-nucleotide 2'-phosphodiesterase/5'-nucleotidase/3'-nucleotidase | insig. | 25 | 77 |
| | Escherichia coli ECOR38 | HEPCGN_12315 | | multifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'-nucleotidase/3'-nucleotidase | insig. | 26 | 77 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS22745 | | bifunctional UDP-sugar hydrolase/5'-nucleotidase | insig. | 25 | 77 |
| | Escherichia fergusonii Becca | EFB2_04675 | | Mannosylglucosyl-3-phosphoglycerate phosphatase | insig. | 25 | 77 |
| | Escherichia coli ECOR38 | HEPCGN_12325 | | multifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'-nucleotidase/3'-nucleotidase | insig. | 25 | 77 |
| | Escherichia coli ECOR38 | HEPCGN_12330 | | multifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'-nucleotidase/3'-nucleotidase | insig. | 26 | 67 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_20715 | | metallophosphatase | cofit | 28 | 45 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_01578 | | Ser/Thr phosphatase family protein | insig. | 28 | 44 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS22740 | | bifunctional UDP-sugar hydrolase/5'-nucleotidase | insig. | 26 | 74 |
| | Escherichia fergusonii Becca | EFB2_04676 | | Mannosylglucosyl-3-phosphoglycerate phosphatase | insig. | 26 | 74 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS03625 | | metallophosphoesterase | insig. | 29 | 38 |
| | Shewanella loihica PV-4 | Shew_2135 | ushA | bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor (RefSeq) | insig. | 27 | 61 |
| | Variovorax sp. SCN45 | GFF5698 | | 2',3'-cyclic-nucleotide 2'-phosphodiesterase (EC 3.1.4.16) / 3'-nucleotidase (EC 3.1.3.6) | insig. | 25 | 91 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c12170 | | putative 5'-nucleotidase | insig. | 29 | 51 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT2440 | | 5'-nucleotidase precursor (NCBI ptt file) | sig. | 30 | 40 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1283 | | 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases | insig. | 24 | 78 |
| | Dickeya dianthicola 67-19 | HGI48_RS05865 | | bifunctional UDP-sugar hydrolase/5'-nucleotidase | insig. | 26 | 65 |
| | Ralstonia solanacearum GMI1000 | RS_RS16850 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 23 | 84 |
| | Dickeya dianthicola ME23 | DZA65_RS06190 | | bifunctional UDP-sugar hydrolase/5'-nucleotidase | insig. | 26 | 65 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_10820 | | bifunctional UDP-sugar hydrolase/5'-nucleotidase | insig. | 25 | 65 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS04330 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 24 | 84 |
| | Cellulophaga baltica 18 | M666_RS17695 | | metallophosphatase | insig. | 29 | 40 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS00800 | | metallophosphoesterase | no data | 30 | 40 |
| | Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS01000 | | metallophosphoesterase | no data | 30 | 40 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_14925 | | bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA | insig. | 25 | 61 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2924 | | 5'-nucleotidase (EC 3.1.3.5) | insig. | 22 | 73 |
| | Dickeya dadantii 3937 | DDA3937_RS05815 | | bifunctional UDP-sugar hydrolase/5'-nucleotidase | insig. | 25 | 65 |
| | Pectobacterium carotovorum WPP14 | HER17_RS15670 | | bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA | cofit | 25 | 65 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS08230 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 23 | 84 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS09040 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 23 | 84 |
| | Ralstonia solanacearum UW163 | UW163_RS04555 | | bifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase | insig. | 23 | 84 |
| | Klebsiella michiganensis M5al | BWI76_RS06865 | | bifunctional UDP-sugar hydrolase/5'-nucleotidase | insig. | 26 | 61 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4400 | | 'UDP-sugar hydrolase (EC 3.6.1.45); 5'-nucleotidase (EC 3.1.3.5)' transl_table=11 | insig. | 27 | 63 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c30230 | | 2',3'-cyclic-nucleotide 2'-phosphodiesterase CpdB | cofit | 29 | 43 |
| | Escherichia coli ECRC100 | OKFHMN_08110 | ushA | bifunctional UDP-sugar hydrolase/5'-nucleotidase | cofit | 24 | 63 |
| | Escherichia coli ECRC101 | MCAODC_27330 | ushA | bifunctional UDP-sugar hydrolase/5'-nucleotidase | insig. | 24 | 63 |
| | Escherichia coli ECRC102 | NIAGMN_06160 | ushA | bifunctional UDP-sugar hydrolase/5'-nucleotidase | cofit | 24 | 63 |
| | Escherichia coli ECRC98 | JDDGAC_11755 | ushA | bifunctional UDP-sugar hydrolase/5'-nucleotidase | insig. | 24 | 63 |
| | Escherichia coli ECRC99 | KEDOAH_19860 | ushA | bifunctional UDP-sugar hydrolase/5'-nucleotidase | no data | 24 | 63 |
| | Erwinia tracheiphila HP pepo 2.2 | IJEDHG_16700 | ushA | bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA | insig. | 25 | 65 |
| | Erwinia tracheiphila SCR3 | LU632_RS18065 | ushA | bifunctional UDP-sugar hydrolase/5'-nucleotidase UshA | insig. | 25 | 65 |
| | Escherichia coli ECOR38 | HEPCGN_06730 | ushA | bifunctional UDP-sugar hydrolase/5'-nucleotidase | insig. | 25 | 63 |
| | Serratia liquefaciens MT49 | IAI46_05290 | | bifunctional UDP-sugar hydrolase/5'-nucleotidase | insig. | 27 | 52 |