| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Caulobacter crescentus NA1000 | CCNA_03749 | | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | insig. | 100 | 100 |
| o | Caulobacter crescentus NA1000 Δfur | CCNA_03749 | | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | cofit | 100 | 100 |
| o | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS13810 | | alpha/beta hydrolase | insig. | 56 | 98 |
| o | Sphingomonas koreensis DSMZ 15582 | Ga0059261_2113 | | Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) | cofit | 50 | 100 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1492 | | Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) | sig. | 45 | 99 |
| o | Sphingobium sp. HT1-2 | GFF1443 | | Putative hydrolase | insig. | 44 | 99 |
| | Rhizobium sp. OAE497 | ABIE40_RS00740 | | alpha/beta hydrolase | no data | 43 | 91 |
| o | Rhizobium sp. OAE497 | ABIE40_RS06020 | | alpha/beta hydrolase | no data | 43 | 91 |
| o | Bosea sp. OAE506 | ABIE41_RS19970 | | alpha/beta hydrolase | sig. | 38 | 98 |
| o | Ralstonia solanacearum GMI1000 | RS_RS07920 | | alpha/beta hydrolase | insig. | 37 | 85 |
| o | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS01815 | | alpha/beta hydrolase | insig. | 36 | 85 |
| o | Ralstonia solanacearum UW163 | UW163_RS15125 | | alpha/beta hydrolase | insig. | 36 | 85 |
| o | Ralstonia solanacearum PSI07 | RPSI07_RS15675 | | alpha/beta hydrolase | sig. | 36 | 85 |
| o | Rhodospirillum rubrum S1H | Rru_A1838 | | Alpha/beta hydrolase fold (NCBI) | insig. | 40 | 88 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS05255 | | alpha/beta hydrolase | insig. | 34 | 84 |
| o | Herbaspirillum seropedicae SmR1 | HSERO_RS09845 | | alpha/beta hydrolase | sig. | 35 | 90 |
| o | Ralstonia sp. UNC404CL21Col | ABZR87_RS13755 | | alpha/beta hydrolase | insig. | 35 | 87 |
| o | Dinoroseobacter shibae DFL-12 | Dshi_2701 | | alpha/beta hydrolase fold (RefSeq) | insig. | 35 | 97 |
| o | Burkholderia phytofirmans PsJN | BPHYT_RS13665 | | alpha/beta hydrolase | sig. | 37 | 87 |
| o | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4926 | | Alpha/beta hydrolase fold | strong | 36 | 92 |
| | Paraburkholderia graminis OAS925 | ABIE53_002907 | | pimeloyl-ACP methyl ester carboxylesterase | insig. | 36 | 84 |
| o | Xanthobacter sp. DMC5 | GFF1431 | | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | insig. | 36 | 94 |
| o | Cupriavidus basilensis FW507-4G11 | RR42_RS06575 | | alpha/beta hydrolase | insig. | 35 | 85 |
| o | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_04497 | | Pimeloyl-ACP methyl ester carboxylesterase | insig. | 37 | 84 |
| o | Dechlorosoma suillum PS | Dsui_2820 | | putative hydrolase or acyltransferase of alpha/beta superfamily | cofit | 33 | 95 |
| o | Azospirillum sp. SherDot2 | MPMX19_01040 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 37 | 91 |
| o | Variovorax sp. SCN45 | GFF404 | | Hydrolase, alpha/beta fold family | insig. | 33 | 90 |
| o | Variovorax sp. OAS795 | ABID97_RS17245 | | alpha/beta hydrolase | insig. | 35 | 88 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c04600 | | Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) | insig. | 35 | 79 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_361 | | Alpha/beta hydrolase fold | sig. | 35 | 88 |
| o | Azospirillum brasilense Sp245 | AZOBR_RS16350 | | alpha/beta hydrolase | insig. | 35 | 91 |
| o | Castellaniella sp019104865 MT123 | ABCV34_RS04955 | | alpha/beta hydrolase | insig. | 33 | 90 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF5117 | | D-(-)-3-hydroxybutyrate oligomer hydrolase | insig. | 33 | 95 |
| o | Magnetospirillum magneticum AMB-1 | AMB_RS06715 | | alpha/beta hydrolase | cofit | 33 | 88 |
| | Ralstonia solanacearum GMI1000 | RS_RS20890 | | alpha/beta hydrolase | insig. | 34 | 85 |
| | Variovorax sp. SCN45 | GFF507 | | Hydrolase, alpha/beta fold family | insig. | 32 | 95 |
| o | Pseudomonas fluorescens SBW25 | PFLU_RS14970 | | alpha/beta hydrolase | insig. | 31 | 91 |
| o | Pseudomonas fluorescens SBW25-INTG | PFLU_RS14970 | | alpha/beta hydrolase | sig. | 31 | 91 |
| | Variovorax sp. OAS795 | ABID97_RS17670 | | alpha/beta hydrolase | sig. | 31 | 95 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS03205 | | alpha/beta hydrolase | insig. | 31 | 89 |
| o | Pseudomonas orientalis W4I3 | QF045_RS19825 | | alpha/beta hydrolase | insig. | 30 | 91 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_72 | | D-(-)-3-hydroxybutyrate oligomer hydrolase | insig. | 31 | 95 |
| o | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02001 | | 2-(acetamidomethylene)succinate hydrolase | cofit | 29 | 91 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS19710 | | hydrolase | insig. | 28 | 88 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_28660 | | hydrolase | insig. | 29 | 93 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1229 | | Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) | insig. | 29 | 87 |
| | Pseudomonas sp. S08-1 | OH686_05455 | | Beta-ketoadipate enol-lactone hydrolase | insig. | 36 | 42 |
| | Pseudomonas sp. SVBP6 | COO64_RS19025 | | alpha/beta hydrolase | insig. | 38 | 39 |
| | Klebsiella michiganensis M5al | BWI76_RS08280 | | acyl-CoA esterase | strong | 35 | 40 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_04256 | | 3-oxoadipate enol-lactonase 2 | cofit | 33 | 43 |
| | Pseudomonas segetis P6 | ACVTMO_RS16130 | | alpha/beta fold hydrolase | insig. | 32 | 48 |
| | Pseudomonas simiae WCS417 | PS417_20530 | | 3-oxoadipate enol-lactonase | insig. | 32 | 43 |
| | Pseudomonas putida KT2440 | PP_4540 | | Hydrolase, alpha/beta fold family | sig. | 32 | 42 |
| | Paraburkholderia graminis OAS925 | ABIE53_004439 | | pimeloyl-ACP methyl ester carboxylesterase | insig. | 33 | 44 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS22225 | | alpha/beta fold hydrolase | insig. | 32 | 43 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS22225 | | alpha/beta fold hydrolase | insig. | 32 | 43 |
| | Pseudomonas sp. DMC3 | GFF2349 | | 3-oxoadipate enol-lactonase 2 | cofit | 33 | 42 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_18275 | | 3-oxoadipate enol-lactonase | insig. | 32 | 42 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_4459 | | Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) | insig. | 32 | 42 |
| | Pseudomonas sp. SVBP6 | COO64_RS21960 | | alpha/beta fold hydrolase | insig. | 31 | 42 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_16605 | | esterase | insig. | 35 | 40 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_04240 | | 3-oxoadipate enol-lactonase | insig. | 31 | 42 |
| | Pseudomonas sp. BP01 | JOY50_RS01265 | | alpha/beta fold hydrolase | insig. | 31 | 42 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS20310 | | alpha/beta hydrolase | insig. | 32 | 45 |
| | Enterobacter sp. TBS_079 | MPMX20_02280 | | Haloalkane dehalogenase | insig. | 32 | 36 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_549 | | Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) | insig. | 29 | 48 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_2683 | | Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) | sig. | 31 | 42 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_1186 | | Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) | insig. | 35 | 36 |
| | Escherichia fergusonii Becca | EFB2_03408 | | Esterase YbfF | insig. | 34 | 40 |
| | Escherichia coli ECOR27 | NOLOHH_23490 | ybfF | esterase | sig. | 34 | 40 |
| | Escherichia coli ECOR38 | HEPCGN_01115 | ybfF | esterase | insig. | 34 | 40 |
| | Escherichia coli ECRC62 | BNILDI_21495 | ybfF | esterase | cofit | 34 | 40 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS03720 | | esterase | insig. | 34 | 40 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03808 | | Pimeloyl-ACP methyl ester carboxylesterase | insig. | 31 | 44 |
| | Pseudomonas sp. DMC3 | GFF4803 | | 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxy late synthase | cofit | 36 | 39 |
| | Pseudomonas segetis P6 | ACVTMO_RS13295 | | alpha/beta fold hydrolase | insig. | 35 | 39 |
| | Azospirillum sp. SherDot2 | MPMX19_03680 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 27 | 85 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02650 | | Pimeloyl-ACP methyl ester carboxylesterase | insig. | 32 | 46 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS18965 | | alpha/beta hydrolase | insig. | 29 | 83 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5880 | | hydrolase, alpha/beta fold family | insig. | 35 | 39 |
| | Escherichia coli BL21 | ECD_00643 | | acyl-CoA esterase | insig. | 33 | 40 |
| | Escherichia coli ECRC98 | JDDGAC_10760 | ybfF | esterase | insig. | 33 | 40 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03029 | | Esterase YbfF | insig. | 33 | 40 |
| | Escherichia coli ECRC100 | OKFHMN_07110 | ybfF | esterase | insig. | 33 | 40 |
| | Escherichia coli ECRC101 | MCAODC_26325 | ybfF | esterase | sig. | 33 | 40 |
| | Escherichia coli ECRC102 | NIAGMN_05165 | ybfF | esterase | insig. | 33 | 40 |
| | Escherichia coli ECRC99 | KEDOAH_20860 | ybfF | esterase | no data | 33 | 40 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS19760 | | alpha/beta fold hydrolase | sig. | 35 | 39 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_07775 | | alpha/beta hydrolase | insig. | 35 | 39 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS53870 | | alpha/beta fold hydrolase | insig. | 35 | 39 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_19820 | | alpha/beta hydrolase | insig. | 34 | 39 |
| | Pseudomonas sp. RS175 | PFR28_00747 | | (E)-2-((N-methylformamido)methylene)succinate hydrolase | insig. | 30 | 42 |
| | Escherichia coli BW25113 | b0686 | ybfF | hypothetical protein (NCBI) | strong | 33 | 40 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4599 | | Esterase ybfF (EC 3.1.-.-) | cofit | 33 | 40 |
| | Pseudomonas sp. RS175 | PFR28_03070 | | 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase | insig. | 33 | 39 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF278 | | Alpha/beta hydrolase fold | insig. | 30 | 94 |
| | Sinorhizobium meliloti 1021 | SMa1727 | | alpha/beta hydrolase | insig. | 32 | 36 |
| o | Mycobacterium tuberculosis H37Rv | Rv3473c | | Possible peroxidase BpoA (non-haem peroxidase) | insig. | 27 | 82 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS17070 | | alpha/beta hydrolase | insig. | 32 | 37 |
| | Rhizobium sp. OAE497 | ABIE40_RS24300 | | alpha/beta hydrolase | insig. | 35 | 34 |