Homologs of BWI76_RS20860 from Klebsiella michiganensis M5al

aminoglycoside/multidrug transporter subunit AcrD
SEED: RND efflux system, inner membrane transporter CmeB
KEGG: hydrophobic/amphiphilic exporter-1 (mainly G- bacteria), HAE1 family

Top 100 hits from BLASTp (E < 0.01)

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Orth Species Gene Name Description Fitness %Id Cov
  Klebsiella michiganensis M5al BWI76_RS20860 aminoglycoside/multidrug transporter subunit AcrD insig. 100 100
o Klebsiella pneumoniae MKP103 KDGMDA_27695 multidrug efflux RND transporter permease AcrD insig. 95 100
o Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 GFF2188 RND efflux system, inner membrane transporter CmeB cofit 92 100
o Escherichia coli ECOR38 HEPCGN_21140 acrD multidrug efflux RND transporter permease AcrD insig. 92 100
o Escherichia coli ECRC62 BNILDI_12460 acrD multidrug efflux RND transporter permease AcrD insig. 92 100
o Escherichia fergusonii Becca EFB2_01418 Multidrug efflux pump subunit AcrB insig. 92 100
o Escherichia coli BL21 ECD_02361 aminoglycoside/multidrug efflux system insig. 92 100
o Escherichia coli ECOR27 NOLOHH_13650 acrD multidrug efflux RND transporter permease AcrD insig. 92 100
o Escherichia coli BW25113 b2470 acrD aminoglycoside/multidrug efflux system (NCBI) strong 92 100
o Escherichia coli ECRC100 OKFHMN_21970 acrD multidrug efflux RND transporter permease AcrD cofit 92 100
o Escherichia coli ECRC101 MCAODC_12500 acrD multidrug efflux RND transporter permease AcrD insig. 92 100
o Escherichia coli ECRC102 NIAGMN_19740 acrD multidrug efflux RND transporter permease AcrD cofit 92 100
o Escherichia coli ECRC98 JDDGAC_25915 acrD multidrug efflux RND transporter permease AcrD insig. 92 100
o Escherichia coli ECRC99 KEDOAH_06250 acrD multidrug efflux RND transporter permease AcrD no data 92 100
o Escherichia coli Nissle 1917 ECOLIN_RS14090 multidrug efflux RND transporter permease AcrD insig. 92 100
o Escherichia coli HS(pFamp)R (ATCC 700891) OHPLBJKB_01261 Multidrug efflux pump subunit AcrB insig. 92 100
o Enterobacter sp. TBS_079 MPMX20_03331 Multidrug efflux pump subunit AcrB insig. 90 100
o Enterobacter asburiae PDN3 EX28DRAFT_0191 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family insig. 90 100
o Serratia liquefaciens MT49 IAI46_18690 multidrug efflux RND transporter permease AcrD insig. 82 99
o Pantoea sp. MT58 IAI47_05310 multidrug efflux RND transporter permease AcrD insig. 80 100
o Pantoea agglomerans CFBP13505 P0401 PagCFBP13505_RS19855 multidrug efflux RND transporter permease AcrD cofit 81 100
o Erwinia amylovora T8 OLJFJH_10745 multidrug efflux RND transporter permease AcrD insig. 79 100
o Pectobacterium carotovorum WPP14 HER17_RS01560 multidrug efflux RND transporter permease AcrD cofit 79 100
o Rahnella sp. WP5 EX31_RS22805 multidrug efflux RND transporter permease AcrD insig. 79 100
  Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 GFF4379 RND efflux system, inner membrane transporter CmeB sig. 66 98
  Escherichia coli Nissle 1917 ECOLIN_RS02750 efflux RND transporter permease AcrB sig. 66 98
  Escherichia coli BL21 ECD_00413 multidrug efflux system protein strong 66 98
  Escherichia fergusonii Becca EFB2_03596 Multidrug efflux pump subunit AcrB insig. 66 98
  Escherichia coli ECOR27 NOLOHH_01140 acrB efflux RND transporter permease AcrB insig. 66 98
  Escherichia coli ECOR38 HEPCGN_06820 acrB efflux RND transporter permease AcrB strong 66 98
  Escherichia coli ECRC62 BNILDI_22555 acrB efflux RND transporter permease AcrB insig. 66 98
  Escherichia coli HS(pFamp)R (ATCC 700891) OHPLBJKB_03212 Multidrug efflux pump subunit AcrB cofit 66 98
  Escherichia coli BW25113 b0462 acrB multidrug efflux system protein (NCBI) strong 66 98
  Escherichia coli ECRC100 OKFHMN_08205 acrB efflux RND transporter permease AcrB cofit 66 98
  Escherichia coli ECRC101 MCAODC_27430 acrB efflux RND transporter permease AcrB cofit 66 98
  Escherichia coli ECRC102 NIAGMN_06260 acrB efflux RND transporter permease AcrB cofit 66 98
  Escherichia coli ECRC99 KEDOAH_19760 acrB efflux RND transporter permease AcrB no data 66 98
  Enterobacter asburiae PDN3 EX28DRAFT_2496 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family cofit 65 98
  Klebsiella pneumoniae MKP103 KDGMDA_14835 acriflavine resistance protein B strong 65 98
  Enterobacter sp. TBS_079 MPMX20_01064 Multidrug efflux pump subunit AcrB strong 65 98
  Klebsiella michiganensis M5al BWI76_RS06775 multidrug efflux RND transporter permease subunit strong 65 98
  Rahnella sp. WP5 EX31_RS22470 multidrug efflux RND transporter permease subunit cofit 65 98
  Pectobacterium carotovorum WPP14 HER17_RS15740 multidrug efflux RND transporter permease subunit cofit 65 98
  Dickeya dadantii 3937 DDA3937_RS05735 multidrug efflux RND transporter permease subunit strong 65 98
  Serratia liquefaciens MT49 IAI46_05185 multidrug efflux RND transporter permease subunit SdeY cofit 66 98
  Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 GFF2116 RND efflux system, inner membrane transporter CmeB insig. 65 99
  Enterobacter sp. TBS_079 MPMX20_04175 Multidrug export protein AcrF insig. 64 98
  Erwinia amylovora T8 OLJFJH_17855 multidrug efflux RND transporter permease subunit AcrB strong 64 98
  Dickeya dianthicola ME23 DZA65_RS06115 multidrug efflux RND transporter permease subunit strong 64 98
  Shewanella oneidensis MR-1 SO4692 AcrB/AcrD/AcrF family protein (NCBI ptt file) strong 63 100
  Enterobacter asburiae PDN3 EX28DRAFT_3319 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family insig. 64 98
  Dickeya dianthicola 67-19 HGI48_RS05790 multidrug efflux RND transporter permease subunit cofit 64 98
  Azospirillum brasilense Sp245 AZOBR_RS30185 multidrug transporter insig. 62 100
  Burkholderia phytofirmans PsJN BPHYT_RS16170 multidrug efflux RND transporter permease subunit no data 62 99
  Klebsiella pneumoniae MKP103 KDGMDA_06465 hydrophobe/amphiphile efflux-1 family RND transporter insig. 64 98
  Shewanella amazonensis SB2B Sama_3554 AcrB/AcrD/AcrF family protein (RefSeq) strong 62 100
  Paraburkholderia sabiae LMG 24235 QEN71_RS02525 efflux RND transporter permease subunit strong 61 99
  Erwinia tracheiphila HP pepo 2.2 IJEDHG_16580 adeB hydrophobe/amphiphile efflux-1 family RND transporter no data 63 98
  Erwinia tracheiphila SCR3 LU632_RS18185 efflux RND transporter permease subunit no data 63 98
  Shewanella sp. ANA-3 Shewana3_4045 hydrophobe/amphiphile efflux-1 (HAE1) family protein (RefSeq) strong 62 99
  Paraburkholderia bryophila 376MFSha3.1 H281DRAFT_04170 multidrug efflux pump strong 62 99
  Klebsiella michiganensis M5al BWI76_RS25585 multidrug efflux RND transporter permease subunit insig. 63 98
  Paraburkholderia graminis OAS925 ABIE53_003408 multidrug efflux pump strong 62 99
  Azospirillum sp. SherDot2 MPMX19_05884 Multidrug efflux pump subunit AcrB insig. 62 100
  Desulfovibrio vulgaris Hildenborough JW710 DVU2816 multidrug resistance protein (TIGR) sig. 61 100
  Pseudomonas aeruginosa PA14 IKLFDK_23290 multidrug efflux RND transporter permease subunit MexB cofit 62 99
  Pseudomonas segetis P6 MPMX49_00685 Multidrug resistance protein MexB insig. 61 100
  Pantoea sp. MT58 IAI47_14515 multidrug efflux RND transporter permease subunit cofit 63 98
  Pantoea agglomerans CFBP13505 P0401 PagCFBP13505_RS10680 multidrug efflux RND transporter permease subunit cofit 63 98
  Escherichia fergusonii Becca EFB2_00558 Multidrug export protein AcrF insig. 63 99
  Escherichia coli Nissle 1917 ECOLIN_RS18755 multidrug efflux RND transporter permease subunit AcrF insig. 63 99
  Escherichia coli ECOR27 NOLOHH_09440 acrF multidrug efflux RND transporter permease subunit AcrF insig. 63 99
  Escherichia coli HS(pFamp)R (ATCC 700891) OHPLBJKB_00439 Multidrug export protein AcrF insig. 63 99
  Escherichia coli BL21 ECD_03124 multidrug efflux system protein insig. 63 99
  Escherichia coli ECRC62 BNILDI_02080 acrF multidrug efflux RND transporter permease subunit AcrF insig. 63 99
  Escherichia coli BW25113 b3266 acrF multidrug efflux system protein (NCBI) insig. 63 99
  Paraburkholderia sabiae LMG 24235 QEN71_RS29865 efflux RND transporter permease subunit insig. 61 99
  Methylophilus sp. DMC18 GFF2593 Multidrug efflux pump subunit AcrB insig. 61 99
  Pseudomonas sp. S08-1 OH686_16050 Multidrug efflux system, inner membrane proton/drug antiporter (RND type) cofit 60 100
  Cupriavidus basilensis FW507-4G11 RR42_RS32420 multidrug efflux RND transporter permease subunit insig. 60 100
  Rhodospirillum rubrum S1H Rru_A2051 Hydrophobe/amphiphile efflux-1 HAE1 (NCBI) cofit 62 100
  Pseudomonas sp. DMC3 GFF2212 Toluene efflux pump membrane transporter TtgB cofit 60 99
  Pseudomonas sp. SVBP6 COO64_RS26275 efflux RND transporter permease subunit cofit 59 100
  Dyella japonica UNC79MFTsu3.2 ABZR86_RS18285 efflux RND transporter permease subunit insig. 60 100
  Caulobacter crescentus NA1000 CCNA_00850 cation/multidrug efflux pump acrB2 strong 62 98
  Caulobacter crescentus NA1000 Δfur CCNA_00850 cation/multidrug efflux pump acrB2 cofit 62 98
  Pseudomonas fluorescens GW456-L13 PfGW456L13_4581 RND efflux system, inner membrane transporter CmeB strong 60 99
  Pseudomonas fluorescens FW300-N2E3 AO353_17295 multidrug transporter strong 60 99
  Pseudomonas syringae pv. syringae B728a Psyr_4008 Hydrophobe/amphiphile efflux-1 HAE1 strong 59 100
  Pseudomonas syringae pv. syringae B728a ΔmexB Psyr_4008 Hydrophobe/amphiphile efflux-1 HAE1 no data 59 100
  Pseudomonas fluorescens FW300-N2E2 Pf6N2E2_2824 RND efflux system, inner membrane transporter CmeB strong 59 99
  Pseudomonas fluorescens FW300-N1B4 Pf1N1B4_3246 RND efflux system, inner membrane transporter CmeB strong 60 99
  Pseudomonas stutzeri RCH2 Psest_0310 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family strong 59 99
  Ralstonia solanacearum GMI1000 RS_RS21030 multidrug efflux RND transporter permease subunit insig. 60 99
  Xanthomonas campestris pv. campestris strain 8004 Xcc-8004.1794.1 RND efflux system, inner membrane transporter CmeB insig. 60 100
  Pseudomonas putida KT2440 PP_1385 Probable efflux pump membrane transporter TtgB strong 59 100
  Pseudomonas fluorescens FW300-N2C3 AO356_04880 multidrug transporter strong 59 99
  Herbaspirillum seropedicae SmR1 HSERO_RS23055 multidrug transporter insig. 59 100
  Shewanella loihica PV-4 Shew_0032 hydrophobe/amphiphile efflux-1 (HAE1) family protein (RefSeq) strong 60 100
  Pseudomonas sp. BP01 JOY50_RS14445 ttgB multidrug efflux RND transporter permease subunit TtgB cofit 59 100