Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| Bifidobacterium breve UCC2003 | BBR_RS16575 | | (p)ppGpp synthetase | strong | 100 | 100 |
| Escherichia coli BL21 | ECD_03507 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | sig. | 33 | 46 |
| Escherichia fergusonii Becca | EFB2_00138 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | insig. | 33 | 46 |
| Escherichia coli ECOR27 | NOLOHH_07435 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | no data | 33 | 46 |
| Escherichia coli ECOR38 | HEPCGN_14375 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | cofit | 33 | 46 |
| Escherichia coli ECRC101 | OKFHMN_15555 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | insig. | 33 | 46 |
| Escherichia coli ECRC101 | MCAODC_06065 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | insig. | 33 | 46 |
| Escherichia coli ECRC102 | NIAGMN_13315 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | insig. | 33 | 46 |
| Escherichia coli ECRC62 | BNILDI_04080 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | insig. | 33 | 46 |
| Escherichia coli ECRC98 | JDDGAC_19180 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | no data | 33 | 46 |
| Escherichia coli ECRC99 | KEDOAH_12590 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | no data | 33 | 46 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00051 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | cofit | 33 | 46 |
| Escherichia coli Nissle 1917 | ECOLIN_RS20790 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | strong | 33 | 46 |
| Escherichia coli BW25113 | b3650 | spoT | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (NCBI) | strong | 33 | 46 |
| Pseudomonas fluorescens SBW25 | PFLU_RS30490 | | hypothetical protein | insig. | 35 | 54 |
| Pseudomonas fluorescens SBW25-INTG | PFLU_RS30490 | | hypothetical protein | sig. | 35 | 54 |
| Klebsiella michiganensis M5al | BWI76_RS27430 | | (p)ppGpp synthetase | strong | 33 | 46 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF357 | | 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 | strong | 33 | 46 |
| Vibrio cholerae E7946 ATCC 55056 | CSW01_13675 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis(diphosphate) 3'-diphosphatase | insig. | 29 | 61 |
| Enterobacter asburiae PDN3 | EX28DRAFT_3899 | | (p)ppGpp synthetase, RelA/SpoT family | sig. | 32 | 46 |
| Enterobacter sp. TBS_079 | MPMX20_00086 | | Bifunctional (p)ppGpp synthase/hydrolase SpoT | strong | 32 | 46 |
| Erwinia tracheiphila SCR3 | LU632_RS22200 | spoT | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | insig. | 33 | 44 |
| Pantoea sp. MT58 | IAI47_00510 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | sig. | 33 | 44 |
| Desulfovibrio vulgaris Hildenborough JW710 | DVU2083 | relA | GTP pyrophosphokinase (TIGR) | sig. | 32 | 65 |
| Parabacteroides merdae CL09T00C40 | HMPREF1078_RS16595 | | HD domain-containing protein | strong | 29 | 73 |
| Dinoroseobacter shibae DFL-12 | Dshi_0194 | | (p)ppGpp synthetase I, SpoT/RelA (RefSeq) | strong | 39 | 43 |
| Serratia liquefaciens MT49 | IAI46_24895 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | insig. | 33 | 44 |
| Bosea sp. OAE506 | ABIE41_RS19890 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 33 | 57 |
| Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS05505 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | cofit | 35 | 48 |
| Pseudomonas sp. RS175 | PFR28_03223 | | GTP pyrophosphokinase | strong | 34 | 51 |
| Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_3508 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | strong | 34 | 51 |
| Pseudomonas fluorescens FW300-N2C3 | AO356_19060 | | (p)ppGpp synthetase | strong | 34 | 51 |
| Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5723 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | strong | 34 | 51 |
| Acidovorax sp. GW101-3H11 | Ac3H11_362 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I | strong | 34 | 44 |
| Pseudomonas fluorescens GW456-L13 | PfGW456L13_2035 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | strong | 34 | 51 |
| Dickeya dadantii 3937 | DDA3937_RS00180 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | no data | 33 | 44 |
| Dickeya dianthicola ME23 | DZA65_RS22150 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | no data | 33 | 44 |
| Pseudomonas fluorescens SBW25 | PFLU_RS22095 | | GTP diphosphokinase | strong | 33 | 51 |
| Pseudomonas fluorescens SBW25-INTG | PFLU_RS22095 | | GTP diphosphokinase | strong | 33 | 51 |
| Pseudomonas simiae WCS417 | PS417_20150 | | (p)ppGpp synthetase | no data | 33 | 51 |
| Fusobacterium nucleatum SB010 | HUW76_05485 | | GTP pyrophosphokinase | strong | 25 | 55 |
| Dickeya dianthicola 67-19 | HGI48_RS21180 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | no data | 40 | 35 |
| Pectobacterium carotovorum WPP14 | HER17_RS21385 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | cofit | 40 | 35 |
| Pseudomonas sp. S08-1 | OH686_18960 | | Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase , (p)ppGpp synthetase I | cofit | 34 | 52 |
| Pseudomonas fluorescens FW300-N2E3 | AO353_02710 | | (p)ppGpp synthetase | strong | 33 | 51 |
| Pseudomonas syringae pv. syringae B728a | Psyr_3695 | | RelA/SpoT protein | strong | 33 | 51 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_3695 | | RelA/SpoT protein | strong | 33 | 51 |
| Rahnella sp. WP5 | EX31_RS15810 | | bifunctional GTP diphosphokinase/guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase | sig. | 38 | 37 |
| Shewanella amazonensis SB2B | Sama_0264 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | strong | 34 | 50 |
| Acidovorax sp. GW101-3H11 | Ac3H11_2291 | | FIG00911518: hypothetical protein | insig. | 28 | 52 |
| Shewanella sp. ANA-3 | Shewana3_3812 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | strong | 36 | 44 |
| Shewanella oneidensis MR-1 | SO0359 | spoT | guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (NCBI ptt file) | strong | 36 | 44 |
| Magnetospirillum magneticum AMB-1 | AMB_RS11400 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | no data | 35 | 48 |
| Shewanella loihica PV-4 | Shew_3499 | | bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase (RefSeq) | strong | 33 | 42 |
| Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4631 | | (p)ppGpp synthetase, RelA/SpoT family | strong | 32 | 48 |
| Pseudomonas putida KT2440 | PP_1656 | | ATP:GTP 3'-pyrophosphotransferase | strong | 32 | 51 |
| Vibrio cholerae E7946 ATCC 55056 | CSW01_12405 | | GTP diphosphokinase | insig. | 30 | 48 |
| Parabacteroides merdae CL09T00C40 | HMPREF1078_RS04420 | | RelA/SpoT family protein | strong | 25 | 51 |
| Pseudomonas stutzeri RCH2 | Psest_1640 | | (p)ppGpp synthetase, RelA/SpoT family | strong | 34 | 45 |
| Pseudomonas sp. S08-1 | OH686_13550 | | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase / GTP pyrophosphokinase , (p)ppGpp synthetase II | insig. | 34 | 43 |
| Escherichia coli BL21 | ECD_02629 | | (p)ppGpp synthetase I/GTP pyrophosphokinase | strong | 32 | 48 |
| Escherichia fergusonii Becca | EFB2_01133 | | GTP pyrophosphokinase | strong | 32 | 48 |
| Escherichia coli ECOR27 | NOLOHH_12125 | relA | GTP diphosphokinase | cofit | 32 | 48 |
| Escherichia coli ECOR38 | HEPCGN_19500 | relA | GTP diphosphokinase | insig. | 32 | 48 |
| Escherichia coli ECRC101 | OKFHMN_20250 | relA | GTP diphosphokinase | insig. | 32 | 48 |
| Escherichia coli ECRC101 | MCAODC_10775 | relA | GTP diphosphokinase | insig. | 32 | 48 |
| Escherichia coli ECRC102 | NIAGMN_18020 | relA | GTP diphosphokinase | insig. | 32 | 48 |
| Escherichia coli ECRC62 | BNILDI_10630 | relA | GTP diphosphokinase | insig. | 32 | 48 |
| Escherichia coli ECRC98 | JDDGAC_23915 | relA | GTP diphosphokinase | no data | 32 | 48 |
| Escherichia coli ECRC99 | KEDOAH_07880 | relA | GTP diphosphokinase | no data | 32 | 48 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_00947 | | GTP pyrophosphokinase | cofit | 32 | 48 |
| Escherichia coli Nissle 1917 | ECOLIN_RS15515 | | GTP diphosphokinase | cofit | 32 | 48 |
| Escherichia coli BW25113 | b2784 | relA | (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) | strong | 32 | 48 |
| Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS15610 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 27 | 71 |
| Caulobacter crescentus NA1000 | CCNA_01622 | | Rsh ppGpp hydrolase-synthetase | strong | 36 | 43 |
| Caulobacter crescentus NA1000 Δfur | CCNA_01622 | | Rsh ppGpp hydrolase-synthetase | cofit | 36 | 43 |
| Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.1215.1 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase II / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) | no data | 32 | 45 |
| Pantoea sp. MT58 | IAI47_04120 | | GTP diphosphokinase | strong | 31 | 48 |
| Phocaeicola dorei CL03T12C01 | ABI39_RS14150 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 29 | 54 |
| Phocaeicola vulgatus CL09T03C04 | HMPREF1058_RS17885 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 29 | 54 |
| Ralstonia sp. UNC404CL21Col | ABZR87_RS15225 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 34 | 56 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4925 | | GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I | strong | 33 | 44 |
| Enterobacter asburiae PDN3 | EX28DRAFT_2864 | | (p)ppGpp synthetase, RelA/SpoT family | strong | 32 | 48 |
| Enterobacter sp. TBS_079 | MPMX20_03653 | | GTP pyrophosphokinase | strong | 32 | 48 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF4837 | | 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 | strong | 32 | 48 |
| Shewanella amazonensis SB2B | Sama_1033 | | GTP diphosphokinase (RefSeq) | strong | 27 | 76 |
| Desulfovibrio vulgaris Miyazaki F | DvMF_0787 | | (p)ppGpp synthetase I, SpoT/RelA (RefSeq) | strong | 32 | 65 |
| Dechlorosoma suillum PS | Dsui_2816 | | (p)ppGpp synthetase, RelA/SpoT family | strong | 34 | 50 |
| Erwinia tracheiphila SCR3 | LU632_RS06350 | relA | GTP diphosphokinase | cofit | 31 | 48 |
| Klebsiella michiganensis M5al | BWI76_RS22805 | | GTP diphosphokinase | strong | 31 | 48 |
| Variovorax sp. SCN45 | GFF403 | | Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I | cofit | 31 | 44 |
| Bacteroides stercoris CC31F | HMPREF1181_RS16240 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 27 | 59 |
| Rhodopseudomonas palustris CGA009 | TX73_013955 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | strong | 34 | 44 |
| Pseudomonas stutzeri RCH2 | Psest_3817 | | (p)ppGpp synthetase, RelA/SpoT family | no data | 32 | 42 |
| Dickeya dianthicola 67-19 | HGI48_RS17070 | | GTP diphosphokinase | cofit | 31 | 48 |
| Dyella japonica UNC79MFTsu3.2 | ABZR86_RS11850 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | no data | 33 | 49 |
| Bifidobacterium breve UCC2003 | BBR_RS16410 | | bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase | no data | 33 | 37 |
| Dickeya dadantii 3937 | DDA3937_RS17015 | | GTP diphosphokinase | strong | 31 | 48 |
| Dickeya dianthicola ME23 | DZA65_RS18145 | | GTP diphosphokinase | sig. | 31 | 48 |
| Pectobacterium carotovorum WPP14 | HER17_RS04115 | | GTP diphosphokinase | strong | 31 | 48 |