| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Agrobacterium fabrum C58 | Atu3603 | | two component response regulator | insig. | 100 | 100 |
| o | Rhizobium sp. OAE497 | ABIE40_RS17545 | | response regulator | insig. | 86 | 100 |
| o | Sinorhizobium meliloti 1021 | SMc00720 | | 2-component receiver domain-containing protein | insig. | 80 | 100 |
| o | Rhodopseudomonas palustris CGA009 | TX73_024620 | | response regulator | insig. | 59 | 100 |
| o | Bosea sp. OAE506 | ABIE41_RS05580 | | response regulator | no data | 50 | 98 |
| | Caulobacter crescentus NA1000 | CCNA_00781 | | two-component receiver protein CpdR | strong | 46 | 100 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00781 | | two-component receiver protein CpdR | cofit | 46 | 100 |
| | Xanthobacter sp. DMC5 | GFF4162 | | Response regulator receiver protein CpdR | no data | 41 | 100 |
| | Sphingobium sp. HT1-2 | GFF3766 | | Response regulator | cofit | 43 | 100 |
| | Sinorhizobium meliloti 1021 | SMc04044 | | 2-component receiver domain-containing protein | no data | 42 | 99 |
| | Agrobacterium fabrum C58 | Atu3883 | | chemotaxis response regulator | no data | 41 | 98 |
| | Rhizobium sp. OAE497 | ABIE40_RS16330 | | response regulator CpdR1 | no data | 41 | 98 |
| | Bosea sp. OAE506 | ABIE41_RS08525 | | cell cycle two-component system response regulator CpdR | no data | 40 | 100 |
| | Sphingobium sp. HT1-2 | GFF3118 | | Sensory box histidine kinase/response regulator | cofit | 43 | 98 |
| | Rhodopseudomonas palustris CGA009 | TX73_004670 | | response regulator | no data | 39 | 100 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS10965 | | response regulator | insig. | 42 | 100 |
| | Azospirillum sp. SherDot2 | MPMX19_00868 | | Sensor kinase CckA | cofit | 41 | 92 |
| | Rhodospirillum rubrum S1H | Rru_A2820 | | Multi-sensor Hybrid Histidine Kinase (NCBI) | cofit | 41 | 97 |
| | Azospirillum brasilense Sp245 | AZOBR_RS11105 | | histidine kinase | insig. | 39 | 94 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1569 | | Response regulator receiver domain | sig. | 42 | 92 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS03195 | | PAS domain-containing sensor histidine kinase | cofit | 38 | 97 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS32770 | | histidine kinase | insig. | 38 | 98 |
| | Rhodanobacter sp000427505 FW510-R12 | LRK53_RS14940 | | response regulator | sig. | 36 | 99 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.3196.1 | | response regulator | insig. | 38 | 97 |
| | Lysobacter sp. OAE881 | ABIE51_RS02560 | | PAS domain-containing protein | insig. | 41 | 97 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_02885 | ompR | response regulator | insig. | 36 | 99 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS09370 | cbrB;inference=COORDINATES | two-component system response regulator CbrB | strong | 38 | 98 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_29980 | | two-component system response regulator CbrB | strong | 38 | 98 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS52660 | cbrB;inference=COORDINATES | two-component system response regulator CbrB | strong | 38 | 98 |
| | Azospirillum sp. SherDot2 | MPMX19_04555 | | Sensor histidine kinase RcsC | insig. | 39 | 92 |
| | Pseudomonas sp. BP01 | JOY50_RS23595 | | transporter substrate-binding domain-containing protein | insig. | 38 | 98 |
| | Marinobacter adhaerens HP15 | HP15_328 | | two component, sigma54 specific, transcriptional regulator, Fis family | strong | 37 | 99 |
| | Xanthobacter sp. DMC5 | GFF1252 | | Sensor histidine kinase RcsC | no data | 36 | 98 |
| | Escherichia coli ECOR38 | HEPCGN_22430 | atoC | acetoacetate metabolism transcriptional regulator AtoC | insig. | 38 | 98 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_00180 | | response regulator receiver domain protein | sig. | 37 | 97 |
| | Lysobacter sp. OAE881 | ABIE51_RS14700 | | response regulator | insig. | 35 | 90 |
| | Rhodanobacter denitrificans MT42 | LRK55_RS13375 | | response regulator | insig. | 34 | 99 |
| | Rhodanobacter denitrificans FW104-10B01 | LRK54_RS13635 | | response regulator | insig. | 34 | 99 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0196 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | strong | 32 | 93 |
| | Pseudomonas stutzeri RCH2 | Psest_3963 | | PAS domain S-box | strong | 37 | 93 |
| | Escherichia coli BL21 | ECD_02147 | | fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein | insig. | 38 | 98 |
| | Escherichia fergusonii Becca | EFB2_01635 | | Regulatory protein AtoC | insig. | 38 | 98 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_01490 | | Regulatory protein AtoC | insig. | 38 | 98 |
| | Escherichia coli Nissle 1917 | ECOLIN_RS12965 | | acetoacetate metabolism transcriptional regulator AtoC | no data | 38 | 98 |
| | Escherichia coli BW25113 | b2220 | atoC | fused response regulator of ato operon, in two-component system with AtoS: response regulator/sigma54 interaction protein (NCBI) | insig. | 38 | 98 |
| | Pseudomonas sp. S08-1 | OH686_17260 | | Two-component sensor CbrB: intrcellular carbon:nitrogen balance | strong | 37 | 98 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0990 | | two-component system response regulator (NCBI ptt file) | sig. | 37 | 97 |
| | Pseudomonas stutzeri RCH2 | Psest_0999 | | Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains | strong | 36 | 99 |
| | Pseudomonas segetis P6 | ACVTMO_RS06070 | | sigma-54-dependent transcriptional regulator | no data | 37 | 98 |
| | Pseudomonas syringae pv. syringae B728a | Psyr_0831 | | Two-component response regulator CbrB | sig. | 37 | 98 |
| | Pseudomonas syringae pv. syringae B728a ΔmexB | Psyr_0831 | | Two-component response regulator CbrB | no data | 37 | 98 |
| | Phocaeicola dorei CL03T12C01 | ABI39_RS05370 | | response regulator transcription factor | insig. | 36 | 92 |
| o | Pseudomonas sp. RS175 | PFR28_01718 | | Response regulator receiver protein CpdR | sig. | 35 | 96 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT0366 | | two-component system sensor histidine kinase/response regulator, hybrid ('one component system') (NCBI ptt file) | sig. | 37 | 85 |
| | Parabacteroides merdae CL09T00C40 | HMPREF1078_RS01665 | | response regulator transcription factor | insig. | 33 | 100 |
| | Pontibacter actiniarum KMM 6156, DSM 19842 | CA264_04380 | | response regulator | strong | 33 | 93 |
| | Pseudomonas segetis P6 | ACVTMO_RS15595 | | sigma-54-dependent transcriptional regulator | strong | 38 | 87 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02954 | | Sensor kinase CckA | no data | 35 | 97 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_0209 | | His Kinase A (phospho-acceptor) domain/Response regulator receiver domain/Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase | cofit | 39 | 88 |
| | Pseudomonas sp. S08-1 | OH686_02845 | | Flagellar two-component response regulator FleR | strong | 36 | 96 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_1524 | | Two-component sensor CbrB: intrcellular carbon:nitrogen balance | strong | 36 | 98 |
| | Pseudomonas sp. DMC3 | GFF2294 | | Blue-light-activated protein | insig. | 35 | 90 |
| | Pseudomonas sp. BP01 | JOY50_RS27675 | | sigma-54 dependent transcriptional regulator | cofit | 35 | 98 |
| | Pseudomonas sp. RS175 | PFR28_03718 | | Transcriptional regulatory protein ZraR | strong | 35 | 98 |
| | Pseudomonas putida KT2440 | PP_4696 | | Nitrogen regulation protein NR(I) | strong | 35 | 98 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_10660 | | sigma-54-dependent Fis family transcriptional regulator | cofit | 34 | 96 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03888 | | His Kinase A (phospho-acceptor) domain-containing protein | insig. | 34 | 98 |
| | Pseudomonas orientalis W4I3 | QF045_RS08450 | | sigma-54 dependent transcriptional regulator | insig. | 30 | 97 |
| | Pseudomonas sp. SVBP6 | COO64_RS15090 | | sigma-54 dependent transcriptional regulator | strong | 35 | 98 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_2858 | | Two-component sensor CbrB: intrcellular carbon:nitrogen balance | strong | 35 | 98 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_16075 | | Fis family transcriptional regulator | strong | 35 | 98 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_5156 | | Two-component sensor CbrB: intrcellular carbon:nitrogen balance | strong | 35 | 98 |
| | Cellulophaga baltica 18 | M666_RS19210 | | sigma-54 dependent transcriptional regulator | insig. | 32 | 93 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS25735 | | sigma-54-dependent Fis family transcriptional regulator | strong | 35 | 98 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS25735 | | sigma-54-dependent Fis family transcriptional regulator | strong | 35 | 98 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2107 | | response regulator receiver protein (RefSeq) | strong | 35 | 98 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_04930 | | Transcriptional regulatory protein ZraR | cofit | 35 | 98 |
| | Pseudomonas orientalis W4I3 | QF045_RS26155 | | sigma-54 dependent transcriptional regulator | strong | 35 | 98 |
| | Pseudomonas simiae WCS417 | PS417_23895 | | Fis family transcriptional regulator | no data | 35 | 98 |
| | Rhodopseudomonas palustris CGA009 | TX73_000735 | | response regulator | insig. | 34 | 87 |
| | Pseudomonas sp. DMC3 | GFF3711 | | Sensor histidine kinase RcsC | cofit | 39 | 96 |
| | Pseudomonas sp. DMC3 | GFF4030 | | Transcriptional regulatory protein ZraR | strong | 35 | 98 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_14400 | | Fis family transcriptional regulator | strong | 35 | 98 |
| | Shewanella oneidensis MR-1 | SO3230 | flrC | flagellar regulatory protein C (NCBI ptt file) | cofit | 34 | 97 |
| | Pseudomonas orientalis W4I3 | QF045_RS14130 | | PAS domain-containing protein | insig. | 36 | 87 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1563 | | sensory box histidine kinase/response regulator (TIGR) | insig. | 35 | 97 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0110 | ntrC | sigma-54 dependent transcriptional regulator/response regulator (TIGR) | cofit | 33 | 100 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2370 | | diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) | insig. | 38 | 98 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1993 | | two component, sigma54 specific, transcriptional regulator, Fis family (RefSeq) | sig. | 36 | 100 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS12830 | | PAS domain-containing protein | cofit | 36 | 87 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS12830 | | PAS domain-containing protein | strong | 36 | 87 |
| | Pseudomonas simiae WCS417 | PS417_12140 | | histidine kinase | insig. | 36 | 87 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU3303 | lon | ATP-dependent protease La, truncation (TIGR) | cofit | 34 | 97 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_19555 | | response regulator | insig. | 33 | 98 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_05479 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | insig. | 32 | 87 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_15165 | | DNA-binding response regulator | insig. | 32 | 90 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU3381 | ntrC | transcriptional regulatory protein zraR (TIGR) | strong | 36 | 96 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_01292 | | Regulatory protein AtoC | cofit | 32 | 97 |
| | Marinobacter adhaerens HP15 | HP15_2093 | | signal transduction histidine kinase | cofit | 31 | 95 |
| | Cellulophaga baltica 18 | M666_RS02825 | | sigma-54 dependent transcriptional regulator | strong | 32 | 96 |