| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Dinoroseobacter shibae DFL-12 | Dshi_0471 | | beta-lactamase domain protein (RefSeq) | insig. | 100 | 100 |
| o | Sinorhizobium meliloti 1021 | SM_b20168 | | hypothetical protein | insig. | 53 | 100 |
| o | Xanthobacter sp. DMC5 | GFF3806 | | hypothetical protein | insig. | 48 | 82 |
| o | Azospirillum sp. SherDot2 | MPMX19_02915 | | hypothetical protein | no data | 47 | 81 |
| o | Azospirillum brasilense Sp245 | AZOBR_RS24465 | | beta-lactamase | insig. | 44 | 83 |
| o | Methylophilus sp. DMC18 | GFF2804 | | hypothetical protein | insig. | 36 | 82 |
| | Pseudomonas stutzeri RCH2 | Psest_2058 | | Zn-dependent hydrolases, including glyoxylases | insig. | 38 | 75 |
| | Pseudomonas fluorescens GW456-L13 | PfGW456L13_3519 | | SoxH protein, homolog | sig. | 37 | 75 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_28035 | | MBL fold metallo-hydrolase | insig. | 35 | 84 |
| | Pseudomonas fluorescens FW300-N1B4 | Pf1N1B4_4499 | | SoxH protein, homolog | no data | 37 | 77 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1384 | | SoxH protein, homolog | insig. | 37 | 75 |
| | Pseudomonas sp. RS175 | PFR28_01817 | | Hydroxyacylglutathione hydrolase | insig. | 35 | 77 |
| | Pseudomonas putida KT2440 | PP_2678 | | putative Hydrolase | insig. | 38 | 71 |
| | Pseudomonas sp. BP01 | JOY50_RS02930 | | quinoprotein relay system zinc metallohydrolase 1 | no data | 39 | 71 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_03781 | | Hydroxyacylglutathione hydrolase | cofit | 37 | 76 |
| | Pseudomonas simiae WCS417 | PS417_17440 | | beta-lactamase | insig. | 37 | 71 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1773 | | SoxH protein, homolog | insig. | 30 | 87 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF5416 | | SoxH protein, homolog | no data | 33 | 77 |
| | Azospirillum sp. SherDot2 | MPMX19_04301 | | hypothetical protein | insig. | 32 | 77 |
| | Azospirillum brasilense Sp245 | AZOBR_RS12745 | | beta-lactamase | insig. | 30 | 74 |
| | Dinoroseobacter shibae DFL-12 | Dshi_4154 | | beta-lactamase domain protein (RefSeq) | insig. | 33 | 60 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF4616 | | SoxH protein, homolog | insig. | 28 | 80 |
| | Dinoroseobacter shibae DFL-12 | Dshi_1231 | | beta-lactamase domain protein (RefSeq) | insig. | 28 | 86 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS16000 | | quinoprotein relay system zinc metallohydrolase 1 | insig. | 31 | 80 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS02710 | | Zn-dependent hydrolase | insig. | 29 | 72 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS11490 | | MBL fold metallo-hydrolase | insig. | 30 | 80 |
| | Dinoroseobacter shibae DFL-12 | Dshi_3814 | | beta-lactamase domain protein (RefSeq) | insig. | 27 | 84 |
| | Variovorax sp. OAS795 | ABID97_RS01790 | | MBL fold metallo-hydrolase | insig. | 29 | 73 |
| | Sphingobium sp. HT1-2 | GFF3837 | | MBL-fold metallo-hydrolase superfamily | cofit | 32 | 50 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS16005 | | MBL fold metallo-hydrolase | insig. | 28 | 70 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS11450 | | MBL fold metallo-hydrolase | insig. | 28 | 81 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1607 | | putative cyclase | cofit | 29 | 62 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS20775 | | MBL fold metallo-hydrolase | insig. | 30 | 72 |
| | Ralstonia solanacearum IBSBF1503 | RALBFv3_RS20210 | | MBL fold hydrolase | sig. | 30 | 72 |
| | Ralstonia solanacearum UW163 | UW163_RS18965 | | MBL fold hydrolase | insig. | 30 | 72 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c00420 | | metallo-beta-lactamase-like protein | insig. | 25 | 66 |
| | Ralstonia solanacearum GMI1000 | RS_RS23490 | | MBL fold metallo-hydrolase | no data | 33 | 58 |
| | Ralstonia solanacearum GMI1000 | RS_RS23620 | | MBL fold metallo-hydrolase | no data | 33 | 58 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_890 | | Cyclase | insig. | 26 | 72 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS15865 | | MBL fold metallo-hydrolase | insig. | 30 | 55 |
| | Ralstonia solanacearum GMI1000 | RS_RS20495 | | MBL fold metallo-hydrolase | insig. | 31 | 55 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS35700 | | beta-lactamase domain-containing protein | insig. | 31 | 55 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS14135 | | MBL fold metallo-hydrolase | insig. | 33 | 54 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS02650 | | MBL fold metallo-hydrolase | insig. | 31 | 55 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS22485 | | MBL fold metallo-hydrolase | sig. | 30 | 55 |
| | Mycobacterium tuberculosis H37Rv | Rv0939 | | Possible bifunctional enzyme: 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase) + cyclase/dehydrase | insig. | 28 | 68 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03753 | | Glyoxylase, beta-lactamase superfamily II | insig. | 30 | 55 |
| | Azospirillum sp. SherDot2 | MPMX19_00288 | | hypothetical protein | insig. | 29 | 72 |
| | Variovorax sp. SCN45 | GFF5497 | | MBL-fold metallo-hydrolase superfamily | insig. | 27 | 73 |
| | Ralstonia solanacearum UW163 | UW163_RS18325 | | MBL fold metallo-hydrolase | insig. | 33 | 58 |
| | Rhodopseudomonas palustris CGA009 | TX73_024290 | | MBL fold metallo-hydrolase | insig. | 27 | 72 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c10010 | | putative protein SoxH | insig. | 27 | 81 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS13765 | | MBL fold metallo-hydrolase | insig. | 30 | 55 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1333 | | Zn-dependent hydrolases, including glyoxylases | insig. | 28 | 67 |
| | Kangiella aquimarina DSM 16071 | B158DRAFT_2023 | | Zn-dependent hydrolases, including glyoxylases | insig. | 26 | 67 |
| | Variovorax sp. SCN45 | GFF2171 | | MBL-fold metallohydrolase SPO0683 | insig. | 25 | 72 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF5401 | | probable beta lactamase( EC:3.5.2.6 ) | no data | 27 | 75 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF5259 | | Fumarylacetoacetase (EC 3.7.1.2) | insig. | 26 | 57 |
| | Agrobacterium fabrum C58 | Atu0807 | | metallo-beta-lactamase superfamily protein | strong | 28 | 66 |
| | Mycobacterium tuberculosis H37Rv | Rv1913 | | Conserved hypothetical protein | insig. | 30 | 53 |
| | Variovorax sp. SCN45 | GFF5051 | | MBL-fold metallohydrolase SPO0683 | insig. | 25 | 72 |
| | Variovorax sp. OAS795 | ABID97_RS03975 | | MBL fold metallo-hydrolase | insig. | 28 | 54 |
| | Sinorhizobium meliloti 1021 | SMc00087 | | hydrolase | strong | 30 | 65 |
| | Bosea sp. OAE506 | ABIE41_RS10145 | | MBL fold metallo-hydrolase | strong | 30 | 65 |
| | Bosea sp. OAE506 | ABIE41_RS06770 | | MBL fold metallo-hydrolase | insig. | 30 | 53 |
| | Rhizobium sp. OAE497 | ABIE40_RS12235 | | MBL fold metallo-hydrolase | insig. | 28 | 46 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02656 | | Glyoxylase, beta-lactamase superfamily II | insig. | 28 | 57 |
| | Paraburkholderia graminis OAS925 | ABIE53_004493 | | glyoxylase-like metal-dependent hydrolase (beta-lactamase superfamily II) | insig. | 36 | 21 |
| | Variovorax sp. OAS795 | ABID97_RS26255 | | MBL fold metallo-hydrolase | no data | 26 | 73 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS08770 | | FprA family A-type flavoprotein | cofit | 22 | 65 |
| | Lysobacter sp. OAE881 | ABIE51_RS03355 | | MBL fold metallo-hydrolase | insig. | 26 | 69 |
| | Shewanella loihica PV-4 | Shew_1646 | | beta-lactamase domain-containing protein (RefSeq) | insig. | 24 | 53 |
| | Agrobacterium fabrum C58 | Atu5203 | | beta-lactamase | insig. | 28 | 52 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT4126 | | flavoprotein (NCBI ptt file) | sig. | 22 | 65 |
| | Rhodopseudomonas palustris CGA009 | TX73_005630 | | MBL fold metallo-hydrolase | strong | 27 | 62 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_1687 | | Zn-dependent hydrolases, including glyoxylases | insig. | 29 | 43 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_4509 | | Zn-dependent hydrolases, including glyoxylases | insig. | 24 | 68 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1146 | | putative metallo-beta-lactamase (NCBI ptt file) | strong | 24 | 51 |
| | Shewanella sp. ANA-3 | Shewana3_2197 | | beta-lactamase domain-containing protein (RefSeq) | insig. | 24 | 54 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_04039 | | metallo-beta-lactamase domain protein | strong | 24 | 51 |
| | Xanthobacter sp. DMC5 | GFF4267 | | Hydroxyacylglutathione hydrolase | strong | 29 | 61 |
| | Rhodanobacter sp. FW510-T8 | OKGIIK_06410 | | MBL fold metallo-hydrolase | insig. | 23 | 70 |
| | Alteromonas macleodii MIT1002 | MIT1002_03357 | | hydroxyacylglutathione hydrolase | insig. | 43 | 15 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2853 | | beta-lactamase domain protein (RefSeq) | insig. | 29 | 51 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS08805 | | alkyl/aryl-sulfatase | insig. | 27 | 37 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_03150 | | Linear primary-alkylsulfatase | insig. | 27 | 37 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS44045 | | alkyl/aryl-sulfatase | insig. | 27 | 37 |
| | Shewanella amazonensis SB2B | Sama_1415 | | beta-lactamase-like protein (RefSeq) | insig. | 23 | 66 |
| | Caulobacter crescentus NA1000 | CCNA_00971 | | hydroxyacylglutathione hydrolase | cofit | 29 | 54 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_00971 | | hydroxyacylglutathione hydrolase | cofit | 29 | 54 |
| | Dinoroseobacter shibae DFL-12 | Dshi_1920 | | beta-lactamase domain protein (RefSeq) | insig. | 32 | 54 |
| | Lysobacter sp. OAE881 | ABIE51_RS01550 | | MBL fold metallo-hydrolase | insig. | 29 | 29 |