Conservation of cofitness between SMc01012 and SMc02867 in Sinorhizobium meliloti 1021

66 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sinorhizobium meliloti 1021 1.0 SMc01012 hypothetical protein 1.0 SMc02867 multidrug-efflux system transmembrane protein 0.36 2
Rhizobium sp. OAE497 0.79 ABIE40_RS09685 nitroreductase 0.50 ABIE40_RS24225 efflux RND transporter permease subunit low > 107
Agrobacterium fabrum C58 0.66 Atu1744 nitroreductase family protein 0.72 Atu3202 RND multidrug efflux transporter low > 89
Bosea sp. OAE506 0.48 ABIE41_RS14115 nitroreductase 0.51 ABIE41_RS01595 efflux RND transporter permease subunit — —
Rhodopseudomonas palustris CGA009 0.47 TX73_017620 nitroreductase 0.68 TX73_020235 efflux RND transporter permease subunit low > 86
Caulobacter crescentus NA1000 Δfur 0.40 CCNA_02736 nitroreductase family 0.52 CCNA_00850 cation/multidrug efflux pump acrB2 low > 67
Caulobacter crescentus NA1000 0.40 CCNA_02736 nitroreductase family 0.52 CCNA_00850 cation/multidrug efflux pump acrB2 low > 66
Rhodanobacter sp. FW510-T8 0.39 OKGIIK_10710 Putative NAD(P)H nitroreductase 0.49 OKGIIK_09170 Efflux pump membrane transporter low > 52
Xanthomonas campestris pv. campestris strain 8004 0.39 Xcc-8004.4214.1 Oxygen-insensitive NADPH nitroreductase (EC 1.-.-.-) 0.52 Xcc-8004.1794.1 RND efflux system, inner membrane transporter CmeB low > 74
Rhodanobacter denitrificans FW104-10B01 0.37 LRK54_RS03860 nitroreductase 0.48 LRK54_RS02100 multidrug efflux RND transporter permease subunit low > 59
Sphingomonas koreensis DSMZ 15582 0.37 Ga0059261_1311 Nitroreductase 0.46 Ga0059261_0559 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family low > 68
Lysobacter sp. OAE881 0.37 ABIE51_RS05520 nitroreductase 0.49 ABIE51_RS17980 multidrug efflux RND transporter permease subunit low > 62
Rhodanobacter denitrificans MT42 0.37 LRK55_RS03610 nitroreductase 0.48 LRK55_RS01875 multidrug efflux RND transporter permease subunit low > 63
Dyella japonica UNC79MFTsu3.2 0.35 ABZR86_RS22155 nitroreductase 0.51 ABZR86_RS18285 efflux RND transporter permease subunit low > 74
Burkholderia phytofirmans PsJN 0.32 BPHYT_RS35735 nitroreductase 0.53 BPHYT_RS16170 multidrug efflux RND transporter permease subunit — —
Kangiella aquimarina DSM 16071 0.31 B158DRAFT_1412 Nitroreductase 0.49 B158DRAFT_0733 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family low > 40
Pseudomonas putida KT2440 0.29 PP_4506 Nitroreductase family protein 0.61 PP_3456 Multidrug resistance protein MexB 0.12 75
Pseudomonas fluorescens FW300-N2E2 0.28 Pf6N2E2_2633 Nitroreductase family protein 0.63 Pf6N2E2_1661 RND efflux system, inner membrane transporter CmeB low > 103
Shewanella sp. ANA-3 0.28 Shewana3_2494 nitroreductase (RefSeq) 0.53 Shewana3_4045 hydrophobe/amphiphile efflux-1 (HAE1) family protein (RefSeq) low > 73
Pseudomonas fluorescens FW300-N2C3 0.28 AO356_03990 nitroreductase 0.63 AO356_28730 acriflavine resistance protein B low > 104
Pseudomonas simiae WCS417 0.27 PS417_22730 nitroreductase 0.61 PS417_12585 acriflavine resistance protein B — —
Pseudomonas sp. S08-1 0.27 OH686_20760 Putative NAD(P)H nitroreductase YdjA 0.54 OH686_16050 Multidrug efflux system, inner membrane proton/drug antiporter (RND type) low > 80
Shewanella oneidensis MR-1 0.27 SO2708 nitroreductase family protein (NCBI ptt file) 0.53 SO4692 AcrB/AcrD/AcrF family protein (NCBI ptt file) low > 76
Pseudomonas syringae pv. syringae B728a 0.27 Psyr_3592 Nitroreductase 0.56 Psyr_2282 Hydrophobe/amphiphile efflux-1 HAE1 low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.27 Psyr_3592 Nitroreductase 0.56 Psyr_2282 Hydrophobe/amphiphile efflux-1 HAE1 low > 86
Enterobacter asburiae PDN3 0.27 EX28DRAFT_1766 Nitroreductase 0.54 EX28DRAFT_2496 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.27 GFF3484 FIG002003: Protein YdjA 0.54 GFF4379 RND efflux system, inner membrane transporter CmeB low > 78
Pseudomonas sp. RS175 0.27 PFR28_00799 Putative NAD(P)H nitroreductase YdjA 0.63 PFR28_02463 Multidrug resistance protein MexB low > 88
Pseudomonas fluorescens SBW25-INTG 0.27 PFLU_RS24370 NAD(P)H nitroreductase 0.62 PFLU_RS13280 multidrug efflux RND transporter permease subunit low > 109
Pseudomonas fluorescens SBW25 0.27 PFLU_RS24370 NAD(P)H nitroreductase 0.62 PFLU_RS13280 multidrug efflux RND transporter permease subunit low > 109
Klebsiella michiganensis M5al 0.26 BWI76_RS11590 NAD(P)H nitroreductase 0.54 BWI76_RS06775 multidrug efflux RND transporter permease subunit — —
Escherichia coli Nissle 1917 0.26 ECOLIN_RS09845 NAD(P)H nitroreductase 0.53 ECOLIN_RS02750 efflux RND transporter permease AcrB — —
Escherichia coli ECOR27 0.26 NOLOHH_17330 ydjA NAD(P)H nitroreductase 0.53 NOLOHH_01140 acrB efflux RND transporter permease AcrB — —
Escherichia coli ECRC62 0.26 BNILDI_16115 ydjA NAD(P)H nitroreductase 0.53 BNILDI_22555 acrB efflux RND transporter permease AcrB — —
Escherichia coli BW25113 0.26 b1765 ydjA predicted oxidoreductase (NCBI) 0.53 b0462 acrB multidrug efflux system protein (NCBI) low > 76
Escherichia coli ECOR38 0.26 HEPCGN_05190 ydjA NAD(P)H nitroreductase 0.53 HEPCGN_06820 acrB efflux RND transporter permease AcrB low > 85
Escherichia coli BL21 0.26 ECD_01734 putative oxidoreductase 0.53 ECD_00413 multidrug efflux system protein — —
Escherichia fergusonii Becca 0.26 EFB2_02229 Putative NAD(P)H nitroreductase YdjA 0.53 EFB2_03596 Multidrug efflux pump subunit AcrB low > 86
Escherichia coli ECRC101 0.26 MCAODC_18590 ydjA NAD(P)H nitroreductase 0.53 MCAODC_27430 acrB efflux RND transporter permease AcrB — —
Escherichia coli ECRC101 0.26 OKFHMN_26820 ydjA NAD(P)H nitroreductase 0.53 OKFHMN_08205 acrB efflux RND transporter permease AcrB — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.26 OHPLBJKB_01967 Putative NAD(P)H nitroreductase YdjA 0.53 OHPLBJKB_03212 Multidrug efflux pump subunit AcrB low > 73
Shewanella loihica PV-4 0.26 Shew_1740 nitroreductase (RefSeq) 0.51 Shew_0032 hydrophobe/amphiphile efflux-1 (HAE1) family protein (RefSeq) — —
Escherichia coli ECRC98 0.26 JDDGAC_01395 ydjA NAD(P)H nitroreductase 0.52 JDDGAC_25915 acrD multidrug efflux RND transporter permease AcrD — —
Escherichia coli ECRC99 0.26 KEDOAH_01290 ydjA NAD(P)H nitroreductase 0.53 KEDOAH_19760 acrB efflux RND transporter permease AcrB — —
Escherichia coli ECRC102 0.26 NIAGMN_01245 ydjA NAD(P)H nitroreductase 0.53 NIAGMN_06260 acrB efflux RND transporter permease AcrB — —
Enterobacter sp. TBS_079 0.26 MPMX20_01851 Putative NAD(P)H nitroreductase YdjA 0.54 MPMX20_01064 Multidrug efflux pump subunit AcrB low > 85
Variovorax sp. SCN45 0.26 GFF205 Nitroreductase family protein 0.59 GFF3725 RND efflux system, inner membrane transporter low > 127
Pantoea sp. MT58 0.25 IAI47_08975 NAD(P)H nitroreductase 0.52 IAI47_14515 multidrug efflux RND transporter permease subunit low > 76
Pseudomonas stutzeri RCH2 0.25 Psest_1881 Nitroreductase 0.52 Psest_0310 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family low > 67
Pseudomonas fluorescens FW300-N1B4 0.25 Pf1N1B4_3544 Nitroreductase family protein 0.64 Pf1N1B4_4772 RND efflux system, inner membrane transporter CmeB low > 87
Azospirillum brasilense Sp245 0.25 AZOBR_RS29250 oxidoreductase 0.57 AZOBR_RS05000 acriflavine resistance protein B — —
Pseudomonas fluorescens GW456-L13 0.24 PfGW456L13_4412 Nitroreductase family protein 0.63 PfGW456L13_2954 RND efflux system, inner membrane transporter CmeB low > 87
Castellaniella sp019104865 MT123 0.24 ABCV34_RS04210 nitroreductase 0.56 ABCV34_RS04225 efflux RND transporter permease subunit low > 48
Paraburkholderia bryophila 376MFSha3.1 0.24 H281DRAFT_04933 Nitroreductase 0.53 H281DRAFT_04170 multidrug efflux pump low > 103
Shewanella amazonensis SB2B 0.24 Sama_1457 nitroreductase family protein (RefSeq) 0.52 Sama_3554 AcrB/AcrD/AcrF family protein (RefSeq) low > 62
Erwinia tracheiphila SCR3 0.24 LU632_RS12965 NAD(P)H nitroreductase 0.53 LU632_RS18185 efflux RND transporter permease subunit — —
Dickeya dianthicola 67-19 0.23 HGI48_RS10305 NAD(P)H nitroreductase 0.51 HGI48_RS05790 multidrug efflux RND transporter permease subunit low > 71
Pseudomonas fluorescens FW300-N2E3 0.23 AO353_18485 nitroreductase 0.63 AO353_26845 acriflavine resistance protein B low > 101
Serratia liquefaciens MT49 0.23 IAI46_14320 NAD(P)H nitroreductase 0.52 IAI46_18690 multidrug efflux RND transporter permease AcrD low > 86
Dickeya dianthicola ME23 0.23 DZA65_RS10780 NAD(P)H nitroreductase 0.51 DZA65_RS06115 multidrug efflux RND transporter permease subunit low > 75
Dickeya dadantii 3937 0.22 DDA3937_RS10295 NAD(P)H nitroreductase 0.57 DDA3937_RS07155 multidrug efflux RND transporter permease subunit low > 74
Rahnella sp. WP5 0.22 EX31_RS06310 NAD(P)H nitroreductase 0.54 EX31_RS22470 multidrug efflux RND transporter permease subunit low > 89
Hydrogenophaga sp. GW460-11-11-14-LB1 0.21 GFF5438 Nitroreductase family protein 0.60 GFF3840 RND efflux system, inner membrane transporter CmeB low > 90
Alteromonas macleodii MIT1002 0.21 MIT1002_01842 Putative NAD(P)H nitroreductase YdjA 0.49 MIT1002_00135 Multidrug-efflux transporter MexB low > 70
Acidovorax sp. GW101-3H11 0.21 Ac3H11_4500 nitroreductase 0.60 Ac3H11_4448 RND efflux system, inner membrane transporter CmeB — —
Pectobacterium carotovorum WPP14 0.19 HER17_RS11100 NAD(P)H nitroreductase 0.54 HER17_RS15740 multidrug efflux RND transporter permease subunit low > 75
Acinetobacter radioresistens SK82 0.18 MPMX26_01115 Putative NAD(P)H nitroreductase YdjA 0.47 MPMX26_00689 Multidrug resistance protein MexB low > 36

Not shown: 9 genomes with orthologs for SMc01012 only; 14 genomes with orthologs for SMc02867 only