Conservation of cofitness between Rv0157 and Rv1200 in Mycobacterium tuberculosis H37Rv

68 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Mycobacterium tuberculosis H37Rv 1.0 Rv0157 Probable NAD(P) transhydrogenase (subunit beta) PntB [integral membrane protein] (pyridine nucleotide transhydrogenase subunit beta) (nicotinamide nucleotide transhydrogenase subunit beta) 1.0 Rv1200 Probable conserved integral membrane transport protein low > 58
Sinorhizobium meliloti 1021 0.41 SMc03938 NAD(P) transhydrogenase subunit beta 0.35 SMc01869 transport transmembrane protein low > 103
Azospirillum sp. SherDot2 0.41 MPMX19_01276 NAD(P) transhydrogenase subunit beta 0.27 MPMX19_06787 Fosfomycin resistance protein AbaF low > 112
Variovorax sp. OAS795 0.40 ABID97_RS04440 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta 0.25 ABID97_RS19685 MFS transporter low > 91
Lysobacter sp. OAE881 0.40 ABIE51_RS05560 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta 0.23 ABIE51_RS09760 MFS transporter low > 62
Dyella japonica UNC79MFTsu3.2 0.40 ABZR86_RS22120 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta 0.23 ABZR86_RS07630 MFS transporter low > 74
Rhodopseudomonas palustris CGA009 0.40 TX73_021670 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta 0.30 TX73_012110 MFS transporter — —
Pseudomonas fluorescens FW300-N2C3 0.40 AO356_10870 NAD synthetase 0.33 AO356_22475 MFS transporter low > 104
Pseudomonas fluorescens FW300-N2E3 0.40 AO353_11080 NAD synthetase 0.33 AO353_04405 MFS transporter low > 101
Pseudomonas syringae pv. syringae B728a 0.39 Psyr_5018 NAD(P) transhydrogenase, beta subunit 0.34 Psyr_1278 Citrate-proton symport low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.39 Psyr_5018 NAD(P) transhydrogenase, beta subunit 0.34 Psyr_1278 Citrate-proton symport low > 86
Castellaniella sp019104865 MT123 0.39 ABCV34_RS10180 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta 0.24 ABCV34_RS06385 MFS transporter low > 48
Rhodospirillum rubrum S1H 0.39 Rru_A2181 NAD(P) transhydrogenase, beta subunit (NCBI) 0.30 Rru_A3159 General substrate transporter (NCBI) low > 58
Pseudomonas fluorescens SBW25 0.39 PFLU_RS00545 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta 0.34 PFLU_RS24600 MHS family MFS transporter low > 109
Ralstonia sp. UNC404CL21Col 0.39 ABZR87_RS01355 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta 0.34 ABZR87_RS02005 MFS transporter low > 80
Pseudomonas fluorescens SBW25-INTG 0.39 PFLU_RS00545 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta 0.34 PFLU_RS24600 MHS family MFS transporter low > 109
Pseudomonas sp. RS175 0.39 PFR28_04723 NAD(P) transhydrogenase subunit beta 0.33 PFR28_02541 Fosfomycin resistance protein AbaF low > 88
Pseudomonas fluorescens FW300-N2E2 0.39 Pf6N2E2_4040 NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) 0.33 Pf6N2E2_388 Transporter, MFS superfamily low > 103
Ralstonia solanacearum PSI07 0.39 RPSI07_RS02775 NAD synthetase 0.34 RPSI07_RS10905 MFS transporter low > 81
Azospirillum brasilense Sp245 0.39 AZOBR_RS06435 NAD synthetase 0.23 AZOBR_RS23185 arabinose ABC transporter permease low > 97
Pseudomonas simiae WCS417 0.39 PS417_00560 NAD synthetase 0.34 PS417_22940 MFS transporter low > 88
Pseudomonas fluorescens FW300-N1B4 0.39 Pf1N1B4_1820 NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) 0.33 Pf1N1B4_180 L-Proline/Glycine betaine transporter ProP low > 87
Rahnella sp. WP5 0.39 EX31_RS07210 Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.33 EX31_RS05410 MHS family MFS transporter low > 89
Pseudomonas fluorescens GW456-L13 0.39 PfGW456L13_2752 NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) 0.33 PfGW456L13_1712 Permeases of the major facilitator superfamily low > 87
Rhizobium sp. OAE497 0.39 ABIE40_RS16590 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta 0.32 ABIE40_RS11815 MFS transporter low > 107
Hydrogenophaga sp. GW460-11-11-14-LB1 0.38 GFF2606 NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) 0.28 GFF2799 Predicted thiazole transporter ThiU low > 90
Pectobacterium carotovorum WPP14 0.38 HER17_RS10515 Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.34 HER17_RS17895 MHS family MFS transporter low > 75
Pseudomonas putida KT2440 0.38 PP_0155 pyridine nucleotide transhydrogenase, beta subunit 0.33 PP_1458 putative inner membrane metabolite transport protein YhjE low > 96
Caulobacter crescentus NA1000 0.38 CCNA_03412 NAD(P) transhydrogenase subunit beta PntB 0.23 CCNA_01852 major facilitator superfamily transporter low > 66
Serratia liquefaciens MT49 0.38 IAI46_13270 Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.34 IAI46_24295 MHS family MFS transporter low > 86
Caulobacter crescentus NA1000 Δfur 0.38 CCNA_03412 NAD(P) transhydrogenase subunit beta PntB 0.23 CCNA_01852 major facilitator superfamily transporter low > 67
Ralstonia solanacearum IBSBF1503 0.38 RALBFv3_RS05785 NAD(P) transhydrogenase subunit beta 0.33 RALBFv3_RS06335 MFS transporter low > 76
Klebsiella michiganensis M5al 0.38 BWI76_RS16200 NAD(P) transhydrogenase subunit beta 0.37 BWI76_RS03450 MFS transporter low > 92
Ralstonia solanacearum UW163 0.38 UW163_RS07840 NAD(P) transhydrogenase subunit beta 0.33 UW163_RS07290 MFS transporter — —
Cupriavidus basilensis FW507-4G11 0.38 RR42_RS17505 NAD synthetase 0.33 RR42_RS26230 MFS transporter low > 128
Dickeya dianthicola 67-19 0.38 HGI48_RS10910 Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.32 HGI48_RS03435 MHS family MFS transporter low > 71
Dickeya dadantii 3937 0.38 DDA3937_RS10960 Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.33 DDA3937_RS03295 MHS family MFS transporter low > 74
Escherichia coli HS(pFamp)R (ATCC 700891) 0.38 OHPLBJKB_02124 NAD(P) transhydrogenase subunit beta 0.31 OHPLBJKB_00179 Inner membrane metabolite transport protein YhjE low > 73
Escherichia coli Nissle 1917 0.38 ECOLIN_RS08950 Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.31 ECOLIN_RS20150 MFS transporter low > 55
Escherichia coli ECRC101 0.38 MCAODC_17715 pntB Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.31 MCAODC_06735 yhjE Inner membrane metabolite transport protein YhjE low > 87
Escherichia coli ECRC102 0.38 NIAGMN_00380 pntB Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.31 NIAGMN_13985 yhjE Inner membrane metabolite transport protein YhjE — —
Escherichia coli ECOR27 0.38 NOLOHH_18200 pntB Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.31 NOLOHH_08185 yhjE Inner membrane metabolite transport protein YhjE low > 75
Escherichia coli BL21 0.38 ECD_01571 pyridine nucleotide transhydrogenase, beta subunit 0.31 ECD_03371 putative MFS transporter; membrane protein low > 61
Dickeya dianthicola ME23 0.38 DZA65_RS11370 Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.31 DZA65_RS03480 MHS family MFS transporter 0.38 31
Sphingomonas koreensis DSMZ 15582 0.38 Ga0059261_1973 NAD/NADP transhydrogenase beta subunit 0.26 Ga0059261_0247 Arabinose efflux permease low > 68
Escherichia coli ECRC62 0.38 BNILDI_16990 pntB Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.31 BNILDI_03370 yhjE Inner membrane metabolite transport protein YhjE low > 75
Escherichia coli ECRC100 0.38 OKFHMN_27695 pntB Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.31 OKFHMN_16220 yhjE Inner membrane metabolite transport protein YhjE low > 80
Escherichia coli BW25113 0.38 b1602 pntB pyridine nucleotide transhydrogenase (NCBI) 0.31 b3523 yhjE predicted transporter (NCBI) low > 76
Escherichia coli ECOR38 0.38 HEPCGN_06070 pntB Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.31 HEPCGN_15125 yhjE Inner membrane metabolite transport protein YhjE low > 87
Escherichia coli ECRC98 0.38 JDDGAC_02285 pntB Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.31 JDDGAC_19850 yhjE Inner membrane metabolite transport protein YhjE low > 86
Escherichia coli ECRC99 0.38 KEDOAH_00410 pntB Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.28 KEDOAH_02925 shiA shikimate transporter — —
Escherichia fergusonii Becca 0.38 EFB2_02390 NAD(P) transhydrogenase subunit beta 0.31 EFB2_00285 Inner membrane metabolite transport protein YhjE low > 86
Acinetobacter radioresistens SK82 0.38 MPMX26_00530 NAD(P) transhydrogenase subunit beta 0.37 MPMX26_00605 Inner membrane metabolite transport protein YhjE low > 36
Enterobacter sp. TBS_079 0.38 MPMX20_02032 NAD(P) transhydrogenase subunit beta 0.33 MPMX20_04408 Inner membrane metabolite transport protein YhjE low > 85
Enterobacter asburiae PDN3 0.38 EX28DRAFT_1543 NAD/NADP transhydrogenase beta subunit 0.33 EX28DRAFT_4054 metabolite-proton symporter low > 76
Bosea sp. OAE506 0.37 ABIE41_RS09270 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta 0.22 ABIE41_RS21015 MFS transporter low > 77
Brevundimonas sp. GW460-12-10-14-LB2 0.37 A4249_RS09070 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta 0.31 A4249_RS05430 MFS transporter low > 48
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.37 GFF1795 NAD(P) transhydrogenase subunit beta (EC 1.6.1.2) 0.32 GFF501 Inner membrane metabolite transport protein YhjE low > 78
Bifidobacterium breve UCC2003 0.37 BBR_RS15195 NAD(P) transhydrogenase subunit beta 0.32 BBR_RS10795 MFS transporter low > 34
Ralstonia solanacearum GMI1000 0.37 RS_RS13675 NAD(P) transhydrogenase subunit beta 0.32 RS_RS14285 MFS transporter low > 80
Paraburkholderia graminis OAS925 0.37 ABIE53_000814 NAD(P) transhydrogenase subunit beta 0.33 ABIE53_001309 metabolite-proton symporter low > 113
Erwinia tracheiphila SCR3 0.37 LU632_RS11430 pntB Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.32 LU632_RS00550 MHS family MFS transporter low > 74
Paraburkholderia sabiae LMG 24235 0.37 QEN71_RS26720 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta 0.34 QEN71_RS03550 MFS transporter low > 153
Burkholderia phytofirmans PsJN 0.36 BPHYT_RS03380 NAD(P) transhydrogenase subunit beta 0.33 BPHYT_RS05200 MFS transporter 0.20 36
Herbaspirillum seropedicae SmR1 0.36 HSERO_RS03495 NAD(P) transhydrogenase subunit beta 0.26 HSERO_RS18780 3-(2-hydroxyphenyl) propionic acid transporter low > 78
Paraburkholderia bryophila 376MFSha3.1 0.36 H281DRAFT_04655 NAD(P) transhydrogenase subunit beta 0.33 H281DRAFT_00192 metabolite-proton symporter low > 103
Pantoea sp. MT58 0.36 IAI47_09570 Re/Si-specific NAD(P)(+) transhydrogenase subunit beta 0.35 IAI47_01055 MHS family MFS transporter low > 76
Agrobacterium fabrum C58 0.36 Atu2494 NAD(P)+ transhydrogenase beta chain 0.33 Atu2090 ABC transporter, membrane spanning protein (sugar) low > 89
Pseudomonas sp. S08-1 0.34 OH686_11935 NAD(P) transhydrogenase subunit beta 0.23 OH686_05635 Uncharacterized MFS-type transporter low > 80

Not shown: 16 genomes with orthologs for Rv0157 only; 4 genomes with orthologs for Rv1200 only