Conservation of cofitness between PP_4782 and PP_5097 in Pseudomonas putida KT2440

52 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_4782 Phosphomethylpyrimidine kinase 1.0 PP_5097 homoserine O-acetyltransferase 0.57 9
Pseudomonas fluorescens SBW25 0.88 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.87 PFLU_RS28385 homoserine O-acetyltransferase low > 109
Pseudomonas fluorescens SBW25-INTG 0.88 PFLU_RS26530 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.87 PFLU_RS28385 homoserine O-acetyltransferase 0.41 15
Pseudomonas fluorescens FW300-N2C3 0.88 AO356_15435 hydrogenase 0.88 AO356_13410 homoserine O-acetyltransferase low > 104
Pseudomonas simiae WCS417 0.87 PS417_24600 hydrogenase 0.87 PS417_26740 homoserine acetyltransferase low > 88
Pseudomonas fluorescens FW300-N2E3 0.87 AO353_06350 hydrogenase 0.87 AO353_08180 homoserine O-acetyltransferase low > 101
Pseudomonas fluorescens GW456-L13 0.87 PfGW456L13_1385 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.86 PfGW456L13_1007 Homoserine O-acetyltransferase (EC 2.3.1.31) low > 87
Pseudomonas syringae pv. syringae B728a ΔmexB 0.85 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.86 Psyr_0474 homoserine O-acetyltransferase low > 86
Pseudomonas syringae pv. syringae B728a 0.85 Psyr_4340 phosphomethylpyrimidine kinase, putative 0.86 Psyr_0474 homoserine O-acetyltransferase low > 86
Pseudomonas sp. RS175 0.84 PFR28_03843 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.88 PFR28_04245 Homoserine O-succinyltransferase 0.38 32
Pseudomonas sp. S08-1 0.82 OH686_09185 Hydroxymethylpyrimidine phosphate kinase ThiD 0.89 OH686_11000 homoserine O-acetyltransferase 0.66 13
Pseudomonas fluorescens FW300-N2E2 0.78 Pf6N2E2_5024 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.85 Pf6N2E2_4597 Homoserine O-acetyltransferase (EC 2.3.1.31) low > 103
Pseudomonas fluorescens FW300-N1B4 0.78 Pf1N1B4_2718 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.88 Pf1N1B4_2338 Homoserine O-acetyltransferase (EC 2.3.1.31) low > 87
Pseudomonas stutzeri RCH2 0.78 Psest_0537 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.86 Psest_0280 homoserine O-acetyltransferase low > 67
Dechlorosoma suillum PS 0.40 Dsui_0662 phosphomethylpyrimidine kinase 0.67 Dsui_0741 homoserine O-acetyltransferase — —
Acinetobacter radioresistens SK82 0.38 MPMX26_02438 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.61 MPMX26_00403 Homoserine O-succinyltransferase — —
Herbaspirillum seropedicae SmR1 0.31 HSERO_RS02135 phosphomethylpyrimidine kinase 0.63 HSERO_RS00455 homoserine O-acetyltransferase 0.43 23
Marinobacter adhaerens HP15 0.27 HP15_349 phosphomethylpyrimidine kinase 0.72 HP15_284 homoserine O-acetyltransferase — —
Rhodospirillum rubrum S1H 0.27 Rru_A1102 Phosphomethylpyrimidine kinase (NCBI) 0.47 Rru_A3266 Homoserine O-acetyltransferase (NCBI) — —
Ralstonia solanacearum IBSBF1503 0.26 RALBFv3_RS09905 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.64 RALBFv3_RS09535 homoserine O-acetyltransferase — —
Ralstonia solanacearum UW163 0.26 UW163_RS03675 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.64 UW163_RS04045 homoserine O-acetyltransferase — —
Ralstonia solanacearum PSI07 0.26 RPSI07_RS23455 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.64 RPSI07_RS23815 homoserine O-acetyltransferase — —
Ralstonia solanacearum GMI1000 0.26 RS_RS00495 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.64 RS_RS00135 homoserine O-acetyltransferase — —
Hydrogenophaga sp. GW460-11-11-14-LB1 0.24 GFF249 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.60 GFF2447 Homoserine O-acetyltransferase (EC 2.3.1.31) low > 90
Ralstonia sp. UNC404CL21Col 0.24 ABZR87_RS04830 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.62 ABZR87_RS05200 homoserine O-acetyltransferase — —
Mucilaginibacter yixingensis YX-36 DSM 26809 0.24 ABZR88_RS08810 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.22 ABZR88_RS09555 homoserine O-acetyltransferase — —
Bosea sp. OAE506 0.24 ABIE41_RS21620 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.47 ABIE41_RS23775 homoserine O-acetyltransferase — —
Echinicola vietnamensis KMM 6221, DSM 17526 0.24 Echvi_0215 phosphomethylpyrimidine kinase 0.26 Echvi_3285 homoserine O-acetyltransferase low > 79
Brevundimonas sp. GW460-12-10-14-LB2 0.24 A4249_RS15985 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.08 A4249_RS16165 homoserine O-succinyltransferase — —
Lysobacter sp. OAE881 0.23 ABIE51_RS07970 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.31 ABIE51_RS08680 homoserine O-acetyltransferase — —
Xanthomonas campestris pv. campestris strain 8004 0.23 Xcc-8004.3091.1 hypothetical protein 0.28 Xcc-8004.2337.1 Homoserine O-acetyltransferase (EC 2.3.1.31) low > 74
Dyella japonica UNC79MFTsu3.2 0.23 ABZR86_RS00760 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.29 ABZR86_RS06465 homoserine O-acetyltransferase — —
Caulobacter crescentus NA1000 Δfur 0.23 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase 0.46 CCNA_00559 homoserine O-acetyltransferase — —
Caulobacter crescentus NA1000 0.23 CCNA_03331 phosphomethylpyrimidine kinase/hydroxymethylpyrimidine kinase 0.46 CCNA_00559 homoserine O-acetyltransferase — —
Azospirillum brasilense Sp245 0.23 AZOBR_RS07045 phosphomethylpyrimidine kinase 0.46 AZOBR_RS20475 homoserine acetyltransferase — —
Rhodopseudomonas palustris CGA009 0.22 TX73_020570 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.48 TX73_023025 homoserine O-acetyltransferase — —
Paraburkholderia graminis OAS925 0.22 ABIE53_001125 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.63 ABIE53_000414 homoserine O-acetyltransferase low > 113
Castellaniella sp019104865 MT123 0.22 ABCV34_RS14505 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.58 ABCV34_RS10925 homoserine O-acetyltransferase — —
Rhodanobacter sp. FW510-T8 0.22 OKGIIK_03835 Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.29 OKGIIK_08605 homoserine O-acetyltransferase — —
Paraburkholderia bryophila 376MFSha3.1 0.22 H281DRAFT_04811 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.63 H281DRAFT_02214 homoserine O-acetyltransferase low > 103
Magnetospirillum magneticum AMB-1 0.22 AMB_RS16155 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.46 AMB_RS20100 homoserine O-acetyltransferase — —
Acidovorax sp. GW101-3H11 0.21 Ac3H11_1063 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.61 Ac3H11_4277 Homoserine O-acetyltransferase (EC 2.3.1.31) — —
Azospirillum sp. SherDot2 0.21 MPMX19_06182 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.46 MPMX19_04391 Homoserine O-acetyltransferase — —
Sphingomonas koreensis DSMZ 15582 0.21 Ga0059261_1961 hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.45 Ga0059261_2301 homoserine O-acetyltransferase (EC 2.3.1.31) — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.20 CA264_20430 hydroxymethylpyrimidine/phosphomethylpyrimidine kinase 0.23 CA264_02375 homoserine O-acetyltransferase low > 74
Paraburkholderia sabiae LMG 24235 0.19 QEN71_RS06305 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.63 QEN71_RS00290 homoserine O-acetyltransferase — —
Burkholderia phytofirmans PsJN 0.19 BPHYT_RS04205 kinase 0.63 BPHYT_RS01595 homoserine O-acetyltransferase low > 109
Pedobacter sp. GW460-11-11-14-LB5 0.19 CA265_RS24160 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.22 CA265_RS08175 homoserine O-acetyltransferase low > 88
Variovorax sp. OAS795 0.19 ABID97_RS15330 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 0.63 ABID97_RS02600 homoserine O-acetyltransferase — —
Cupriavidus basilensis FW507-4G11 0.19 RR42_RS01370 phosphomethylpyrimidine kinase 0.64 RR42_RS01160 homoserine O-acetyltransferase — —
Mycobacterium tuberculosis H37Rv 0.18 Rv0422c Probable phosphomethylpyrimidine kinase ThiD (HMP-phosphate kinase) (HMP-P kinase) 0.27 Rv3341 Probable homoserine O-acetyltransferase MetA (homoserine O-trans-acetylase) (homoserine transacetylase) (HTA) — —
Synechococcus elongatus PCC 7942 0.17 Synpcc7942_2379 thiD phosphomethylpyrimidine kinase 0.13 Synpcc7942_1714 metX hypothetical protein low > 38
Variovorax sp. SCN45 0.16 GFF2149 Hydroxymethylpyrimidine phosphate kinase ThiD (EC 2.7.4.7) 0.61 GFF3265 Homoserine O-acetyltransferase (EC 2.3.1.31) low > 127

Not shown: 41 genomes with orthologs for PP_4782 only; 2 genomes with orthologs for PP_5097 only