Conservation of cofitness between HEPCGN_01360 and HEPCGN_07365 in Escherichia coli ECOR38

52 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR38 1.0 HEPCGN_01360 histidine ammonia-lyase 1.0 HEPCGN_07365 frmA S-(hydroxymethyl)glutathione dehydrogenase 0.52 10
Shewanella oneidensis MR-1 0.53 SO3057 Pal/histidase family protein (NCBI ptt file) 0.74 SO2054 adhC alcohol dehydrogenase class III (NCBI ptt file) low > 76
Shewanella loihica PV-4 0.53 Shew_2280 phenylalanine/histidine ammonia-lyase (RefSeq) 0.75 Shew_1540 alcohol dehydrogenase (RefSeq) low > 60
Shewanella sp. ANA-3 0.53 Shewana3_1490 phenylalanine/histidine ammonia-lyase (RefSeq) 0.74 Shewana3_1837 alcohol dehydrogenase (RefSeq) low > 73
Sinorhizobium meliloti 1021 0.38 SMa0306 histidine ammonia-lyase 0.61 SM_b20170 glutathione-dependent formaldehyde dehydrogenase — —
Serratia liquefaciens MT49 0.37 IAI46_10665 aromatic amino acid lyase 0.75 IAI46_07885 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 86
Pseudomonas syringae pv. syringae B728a 0.18 Psyr_4833 histidine ammonia-lyase 0.88 Psyr_2956 Zinc-containing alcohol dehydrogenase superfamily low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.18 Psyr_4833 histidine ammonia-lyase 0.88 Psyr_2956 Zinc-containing alcohol dehydrogenase superfamily low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.18 GFF668 Histidine ammonia-lyase (EC 4.3.1.3) 0.80 GFF2617 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 78
Alteromonas macleodii MIT1002 0.17 MIT1002_00905 Histidine ammonia-lyase 0.75 MIT1002_03089 S-(hydroxymethyl)glutathione dehydrogenase low > 70
Hydrogenophaga sp. GW460-11-11-14-LB1 0.17 GFF3589 Histidine ammonia-lyase (EC 4.3.1.3) 0.60 GFF3318 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) — —
Cupriavidus basilensis FW507-4G11 0.17 RR42_RS14640 histidine ammonia-lyase 0.61 RR42_RS25775 alcohol dehydrogenase — —
Ralstonia solanacearum PSI07 0.17 RPSI07_RS11915 histidine ammonia-lyase 0.61 RPSI07_RS20965 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 81
Pseudomonas fluorescens FW300-N2E3 0.17 AO353_12270 histidine ammonia-lyase 0.75 AO353_16580 S-(hydroxymethyl)glutathione dehydrogenase low > 101
Ralstonia solanacearum GMI1000 0.17 RS_RS13250 histidine ammonia-lyase 0.61 RS_RS17530 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 80
Ralstonia solanacearum UW163 0.17 UW163_RS08235 histidine ammonia-lyase 0.62 UW163_RS01260 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase — —
Ralstonia solanacearum IBSBF1503 0.17 RALBFv3_RS05390 histidine ammonia-lyase 0.62 RALBFv3_RS12345 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Bosea sp. OAE506 0.17 ABIE41_RS21065 aromatic amino acid lyase 0.61 ABIE41_RS09635 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 77
Variovorax sp. OAS795 0.17 ABID97_RS03420 histidine ammonia-lyase 0.61 ABID97_RS10235 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 91
Pseudomonas sp. S08-1 0.17 OH686_16755 histidine ammonia-lyase 0.75 OH686_18150 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 80
Pseudomonas fluorescens SBW25 0.17 PFLU_RS01805 histidine ammonia-lyase 0.75 PFLU_RS06395 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 109
Pseudomonas fluorescens SBW25-INTG 0.17 PFLU_RS01805 histidine ammonia-lyase 0.75 PFLU_RS06395 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 109
Agrobacterium fabrum C58 0.17 Atu3933 histidine ammonia-lyase 0.60 Atu1670 alcohol dehydrogenase class III low > 89
Ralstonia sp. UNC404CL21Col 0.17 ABZR87_RS01025 histidine ammonia-lyase 0.62 ABZR87_RS08285 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 80
Brevundimonas sp. GW460-12-10-14-LB2 0.16 A4249_RS06630 histidine ammonia-lyase 0.58 A4249_RS00420 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 48
Pseudomonas sp. RS175 0.16 PFR28_04971 Histidine ammonia-lyase 0.73 PFR28_00420 S-(hydroxymethyl)glutathione dehydrogenase low > 88
Rahnella sp. WP5 0.16 EX31_RS06755 histidine ammonia-lyase 0.74 EX31_RS18715 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 89
Klebsiella michiganensis M5al 0.16 BWI76_RS08740 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.84 BWI76_RS13260 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 92
Rhizobium sp. OAE497 0.16 ABIE40_RS20355 histidine ammonia-lyase 0.61 ABIE40_RS09860 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 107
Sphingomonas koreensis DSMZ 15582 0.16 Ga0059261_3963 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.62 Ga0059261_1819 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 68
Enterobacter asburiae PDN3 0.16 EX28DRAFT_2219 histidine ammonia-lyase (EC 4.3.1.3) 0.83 EX28DRAFT_1257 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Azospirillum sp. SherDot2 0.16 MPMX19_04940 Histidine ammonia-lyase 0.68 MPMX19_05326 S-(hydroxymethyl)glutathione dehydrogenase low > 112
Castellaniella sp019104865 MT123 0.16 ABCV34_RS12780 histidine ammonia-lyase 0.83 ABCV34_RS09045 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 48
Xanthomonas campestris pv. campestris strain 8004 0.16 Xcc-8004.3296.1 Histidine ammonia-lyase (EC 4.3.1.3) 0.84 Xcc-8004.982.1 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 74
Variovorax sp. SCN45 0.16 GFF6409 Histidine ammonia-lyase (EC 4.3.1.3) 0.60 GFF2941 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 127
Paraburkholderia sabiae LMG 24235 0.15 QEN71_RS23515 histidine ammonia-lyase 0.61 QEN71_RS02555 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 153
Caulobacter crescentus NA1000 0.15 CCNA_01010 histidine ammonia-lyase 0.60 CCNA_02601 glutathione-dependent formaldehyde dehydrogenase low > 66
Caulobacter crescentus NA1000 Δfur 0.15 CCNA_01010 histidine ammonia-lyase 0.60 CCNA_02601 glutathione-dependent formaldehyde dehydrogenase low > 67
Kangiella aquimarina DSM 16071 0.15 B158DRAFT_1432 histidine ammonia-lyase (EC 4.3.1.3) 0.75 B158DRAFT_0940 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 40
Enterobacter sp. TBS_079 0.15 MPMX20_01400 Histidine ammonia-lyase 0.83 MPMX20_02209 S-(hydroxymethyl)glutathione dehydrogenase low > 85
Paraburkholderia graminis OAS925 0.15 ABIE53_001729 histidine ammonia-lyase 0.61 ABIE53_003402 S-(hydroxymethyl)glutathione dehydrogenase/alcohol dehydrogenase low > 113
Phaeobacter inhibens DSM 17395 0.15 PGA1_c36340 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.61 PGA1_c02510 S-(hydroxymethyl)glutathione dehydrogenase FrmA low > 62
Paraburkholderia bryophila 376MFSha3.1 0.15 H281DRAFT_04873 histidine ammonia-lyase 0.61 H281DRAFT_04166 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase low > 103
Burkholderia phytofirmans PsJN 0.14 BPHYT_RS07555 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.91 BPHYT_RS00510 S-(hydroxymethyl)glutathione dehydrogenase low > 109
Rhodospirillum rubrum S1H 0.14 Rru_A1301 Histidine ammonia-lyase (NCBI) 0.71 Rru_A3405 Formaldehyde dehydrogenase (glutathione) (NCBI) low > 58
Shewanella amazonensis SB2B 0.14 Sama_1631 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.75 Sama_0004 alcohol dehydrogenase, zinc-binding (RefSeq) low > 62
Pantoea sp. MT58 0.14 IAI47_13275 histidine ammonia-lyase 0.75 IAI47_06705 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Herbaspirillum seropedicae SmR1 0.14 HSERO_RS22680 histidine ammonia-lyase 0.59 HSERO_RS13615 alcohol dehydrogenase low > 78
Rhodanobacter denitrificans FW104-10B01 0.13 LRK54_RS01300 aromatic amino acid ammonia-lyase 0.72 LRK54_RS09935 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 59
Rhodanobacter denitrificans MT42 0.12 LRK55_RS01065 aromatic amino acid lyase 0.72 LRK55_RS09575 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 63
Dyella japonica UNC79MFTsu3.2 0.12 ABZR86_RS06750 histidine ammonia-lyase 0.82 ABZR86_RS17285 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 74
Rhodanobacter sp. FW510-T8 0.12 OKGIIK_05610 hutH histidine ammonia-lyase 0.73 OKGIIK_16185 frmA S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 52
Lysobacter sp. OAE881 0.10 ABIE51_RS13345 aromatic amino acid lyase 0.90 ABIE51_RS18925 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 62

Not shown: 11 genomes with orthologs for HEPCGN_01360 only; 32 genomes with orthologs for HEPCGN_07365 only