Conservation of cofitness between HEPCGN_01360 and HEPCGN_04870 in Escherichia coli ECOR38

49 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR38 1.0 HEPCGN_01360 histidine ammonia-lyase 1.0 HEPCGN_04870 htpX protease HtpX 0.58 4
Shewanella oneidensis MR-1 0.53 SO3057 Pal/histidase family protein (NCBI ptt file) 0.55 SO2728 htpX peptidase HtpX (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.53 Shewana3_1490 phenylalanine/histidine ammonia-lyase (RefSeq) 0.55 Shewana3_2512 heat shock protein HtpX (RefSeq) 0.66 33
Shewanella loihica PV-4 0.53 Shew_2280 phenylalanine/histidine ammonia-lyase (RefSeq) 0.55 Shew_1723 heat shock protein HtpX (RefSeq) low > 60
Sinorhizobium meliloti 1021 0.38 SMa0306 histidine ammonia-lyase 0.16 SMc04091 heat shock protein HtpX low > 103
Serratia liquefaciens MT49 0.37 IAI46_10665 aromatic amino acid lyase 0.89 IAI46_10810 protease HtpX
Vibrio cholerae E7946 ATCC 55056 0.19 CSW01_06080 histidine ammonia-lyase 0.62 CSW01_05670 protease HtpX low > 62
Pseudomonas syringae pv. syringae B728a ΔmexB 0.18 Psyr_4833 histidine ammonia-lyase 0.45 Psyr_3616 Heat shock protein, Metallo peptidase, MEROPS family M48B low > 86
Pseudomonas syringae pv. syringae B728a 0.18 Psyr_4833 histidine ammonia-lyase 0.45 Psyr_3616 Heat shock protein, Metallo peptidase, MEROPS family M48B low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.18 GFF668 Histidine ammonia-lyase (EC 4.3.1.3) 0.98 GFF2844 Probable protease HtpX (EC 3.4.24.-)
Hydrogenophaga sp. GW460-11-11-14-LB1 0.17 GFF3589 Histidine ammonia-lyase (EC 4.3.1.3) 0.42 GFF526 Heat shock protease
Cupriavidus basilensis FW507-4G11 0.17 RR42_RS14640 histidine ammonia-lyase 0.45 RR42_RS19940 heat-shock protein HtpX low > 128
Ralstonia solanacearum GMI1000 0.17 RS_RS13250 histidine ammonia-lyase 0.16 RS_RS00370 protease HtpX low > 80
Ralstonia solanacearum PSI07 0.17 RPSI07_RS11915 histidine ammonia-lyase 0.15 RPSI07_RS23580 zinc metalloprotease HtpX 0.48 39
Pseudomonas fluorescens FW300-N2E3 0.17 AO353_12270 histidine ammonia-lyase 0.45 AO353_19145 protease HtpX low > 101
Ralstonia solanacearum UW163 0.17 UW163_RS08235 histidine ammonia-lyase 0.16 UW163_RS03795 protease
Ralstonia solanacearum IBSBF1503 0.17 RALBFv3_RS05390 histidine ammonia-lyase 0.16 RALBFv3_RS09785 protease low > 76
Pseudomonas sp. S08-1 0.17 OH686_16755 histidine ammonia-lyase 0.47 OH686_22565 Protease HtpX 0.49 56
Variovorax sp. OAS795 0.17 ABID97_RS03420 histidine ammonia-lyase 0.41 ABID97_RS06055 protease HtpX low > 91
Pseudomonas fluorescens SBW25-INTG 0.17 PFLU_RS01805 histidine ammonia-lyase 0.44 PFLU_RS08505 protease HtpX 0.16 101
Pseudomonas fluorescens SBW25 0.17 PFLU_RS01805 histidine ammonia-lyase 0.44 PFLU_RS08505 protease HtpX low > 109
Agrobacterium fabrum C58 0.17 Atu3933 histidine ammonia-lyase 0.20 Atu2826 protease heat shock protein low > 89
Ralstonia sp. UNC404CL21Col 0.17 ABZR87_RS01025 histidine ammonia-lyase 0.16 ABZR87_RS04955 zinc metalloprotease HtpX low > 80
Pseudomonas sp. RS175 0.16 PFR28_04971 Histidine ammonia-lyase 0.45 PFR28_00983 Protease HtpX low > 88
Klebsiella michiganensis M5al 0.16 BWI76_RS08740 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.94 BWI76_RS17970 zinc metalloprotease HtpX low > 92
Rahnella sp. WP5 0.16 EX31_RS06755 histidine ammonia-lyase 0.90 EX31_RS24885 protease HtpX
Enterobacter asburiae PDN3 0.16 EX28DRAFT_2219 histidine ammonia-lyase (EC 4.3.1.3) 0.96 EX28DRAFT_0727 Zn-dependent protease with chaperone function low > 76
Xanthomonas campestris pv. campestris strain 8004 0.16 Xcc-8004.3296.1 Histidine ammonia-lyase (EC 4.3.1.3) 0.54 Xcc-8004.2262.1 Probable protease htpX homolog (EC 3.4.24.-) low > 74
Castellaniella sp019104865 MT123 0.16 ABCV34_RS12780 histidine ammonia-lyase 0.43 ABCV34_RS02205 protease HtpX
Variovorax sp. SCN45 0.16 GFF6409 Histidine ammonia-lyase (EC 4.3.1.3) 0.40 GFF4554 Protease HtpX low > 127
Paraburkholderia sabiae LMG 24235 0.15 QEN71_RS23515 histidine ammonia-lyase 0.16 QEN71_RS00170 zinc metalloprotease HtpX low > 153
Caulobacter crescentus NA1000 0.15 CCNA_01010 histidine ammonia-lyase 0.18 CCNA_02594 heat shock endopeptidase HtpX low > 66
Kangiella aquimarina DSM 16071 0.15 B158DRAFT_1432 histidine ammonia-lyase (EC 4.3.1.3) 0.48 B158DRAFT_2016 Zn-dependent protease with chaperone function low > 40
Caulobacter crescentus NA1000 Δfur 0.15 CCNA_01010 histidine ammonia-lyase 0.18 CCNA_02594 heat shock endopeptidase HtpX low > 67
Fusobacterium nucleatum SB010 0.15 HUW76_04780 histidine ammonia-lyase 0.23 HUW76_05515 M48 family metalloprotease low > 35
Enterobacter sp. TBS_079 0.15 MPMX20_01400 Histidine ammonia-lyase 0.96 MPMX20_02736 Protease HtpX low > 85
Paraburkholderia graminis OAS925 0.15 ABIE53_001729 histidine ammonia-lyase 0.17 ABIE53_000391 heat shock protein HtpX low > 113
Paraburkholderia bryophila 376MFSha3.1 0.15 H281DRAFT_04873 histidine ammonia-lyase 0.17 H281DRAFT_02238 Heat shock protein. Metallo peptidase. MEROPS family M48B low > 103
Burkholderia phytofirmans PsJN 0.14 BPHYT_RS07555 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.17 BPHYT_RS01470 protease HtpX homolog
Rhodospirillum rubrum S1H 0.14 Rru_A1301 Histidine ammonia-lyase (NCBI) 0.16 Rru_A3579 Peptidase M48, Ste24p (NCBI) low > 58
Bacteroides ovatus ATCC 8483 0.14 BACOVA_00991 histidine ammonia-lyase 0.17 BACOVA_03977 peptidase, M48 family low > 94
Shewanella amazonensis SB2B 0.14 Sama_1631 Histidine ammonia-lyase (EC 4.3.1.3) (from data) 0.55 Sama_1443 heat shock protein HtpX (RefSeq)
Herbaspirillum seropedicae SmR1 0.14 HSERO_RS22680 histidine ammonia-lyase 0.44 HSERO_RS16415 heat shock protein HtpX low > 78
Pantoea sp. MT58 0.14 IAI47_13275 histidine ammonia-lyase 0.91 IAI47_08710 protease HtpX 0.36 16
Bacteroides thetaiotaomicron VPI-5482 0.14 BT2690 histidine ammonia-lyase (NCBI ptt file) 0.15 BT1199 putative protease (NCBI ptt file) low > 81
Rhodanobacter denitrificans FW104-10B01 0.13 LRK54_RS01300 aromatic amino acid ammonia-lyase 0.48 LRK54_RS14825 protease HtpX low > 59
Rhodanobacter denitrificans MT42 0.12 LRK55_RS01065 aromatic amino acid lyase 0.48 LRK55_RS14540 protease HtpX low > 63
Dyella japonica UNC79MFTsu3.2 0.12 ABZR86_RS06750 histidine ammonia-lyase 0.47 ABZR86_RS00580 protease HtpX low > 74
Rhodanobacter sp. FW510-T8 0.12 OKGIIK_05610 hutH histidine ammonia-lyase 0.47 OKGIIK_03645 htpX protease HtpX low > 52
Lysobacter sp. OAE881 0.10 ABIE51_RS13345 aromatic amino acid lyase 0.56 ABIE51_RS13515 protease HtpX low > 62

Not shown: 14 genomes with orthologs for HEPCGN_01360 only; 33 genomes with orthologs for HEPCGN_04870 only