Conservation of cofitness between HP15_2497 and HP15_958 in Marinobacter adhaerens HP15

65 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Marinobacter adhaerens HP15 1.0 HP15_2497 HflK 1.0 HP15_958 small multidrug resistance protein 0.54 10
Pseudomonas fluorescens SBW25 0.43 PFLU_RS02580 FtsH protease activity modulator HflK 0.53 PFLU_RS02410 multidrug efflux SMR transporter low > 109
Pseudomonas fluorescens SBW25-INTG 0.43 PFLU_RS02580 FtsH protease activity modulator HflK 0.53 PFLU_RS02410 multidrug efflux SMR transporter low > 109
Pseudomonas syringae pv. syringae B728a ΔmexB 0.43 Psyr_0574 protease FtsH subunit HflK 0.56 Psyr_0541 Small multidrug resistance protein low > 86
Pseudomonas syringae pv. syringae B728a 0.43 Psyr_0574 protease FtsH subunit HflK 0.56 Psyr_0541 Small multidrug resistance protein low > 86
Pseudomonas fluorescens FW300-N1B4 0.42 Pf1N1B4_1410 HflK protein 0.56 Pf1N1B4_1451 Ethidium bromide-methyl viologen resistance protein EmrE — —
Pseudomonas fluorescens FW300-N2C3 0.42 AO356_08645 hypothetical protein 0.55 AO356_08830 multidrug DMT transporter low > 104
Pseudomonas fluorescens FW300-N2E3 0.42 AO353_13155 hypothetical protein 0.54 AO353_12990 multidrug DMT transporter low > 101
Pseudomonas putida KT2440 0.41 PP_4892 integral membrane ATP-dependent zinc metallopeptidase / HflK-HflC complex 0.55 PP_4930 putative small multidrug resistance protein low > 96
Pseudomonas simiae WCS417 0.41 PS417_02500 membrane protein 0.53 PS417_02335 multidrug DMT transporter — —
Pseudomonas sp. RS175 0.41 PFR28_05123 Modulator of FtsH protease HflK 0.55 PFR28_05087 Multidrug transporter low > 88
Pseudomonas fluorescens FW300-N2E2 0.41 Pf6N2E2_3612 HflK protein 0.55 Pf6N2E2_3648 Ethidium bromide-methyl viologen resistance protein EmrE low > 103
Pseudomonas fluorescens GW456-L13 0.40 PfGW456L13_152 HflK protein 0.57 PfGW456L13_191 Ethidium bromide-methyl viologen resistance protein EmrE low > 87
Pseudomonas sp. S08-1 0.40 OH686_09460 HflK protein 0.59 OH686_09575 small multidrug resistance family (SMR) protein low > 80
Vibrio cholerae E7946 ATCC 55056 0.37 CSW01_01845 protease modulator HflK 0.29 CSW01_06990 QacE family quaternary ammonium compound efflux SMR transporter low > 62
Alteromonas macleodii MIT1002 0.37 MIT1002_03786 Modulator of FtsH protease HflK 0.29 MIT1002_00131 Quaternary ammonium compound-resistance protein SugE low > 70
Shewanella sp. ANA-3 0.37 Shewana3_0599 HflK protein (RefSeq) 0.29 Shewana3_1676 small multidrug resistance protein (RefSeq) — —
Shewanella oneidensis MR-1 0.37 SO0605 hflK hflK protein (NCBI ptt file) 0.45 SOA0159 multidrug efflux transporter (NCBI ptt file) low > 76
Enterobacter asburiae PDN3 0.35 EX28DRAFT_3371 HflK protein 0.34 EX28DRAFT_3348 Membrane transporters of cations and cationic drugs low > 76
Escherichia coli ECOR38 0.34 HEPCGN_10475 hflK FtsH protease activity modulator HflK 0.44 HEPCGN_14155 emrE QacE family quaternary ammonium compound efflux SMR transporter low > 85
Escherichia fergusonii Becca 0.34 EFB2_04361 Modulator of FtsH protease HflK 0.58 EFB2_02010 Multidrug transporter EmrE low > 86
Escherichia coli Nissle 1917 0.34 ECOLIN_RS24240 FtsH protease activity modulator HflK 0.58 ECOLIN_RS11040 multidrug efflux SMR transporter EmrE — —
Escherichia coli ECRC62 0.33 BNILDI_06980 hflK FtsH protease activity modulator HflK 0.32 BNILDI_06855 sugE quaternary ammonium compound efflux SMR transporter SugE — —
Escherichia coli ECRC99 0.33 KEDOAH_15910 hflK FtsH protease activity modulator HflK 0.58 KEDOAH_24875 emrE multidrug efflux SMR transporter EmrE — —
Escherichia coli ECRC101 0.33 OKFHMN_12245 hflK FtsH protease activity modulator HflK 0.58 OKFHMN_00790 emrE multidrug efflux SMR transporter EmrE — —
Escherichia coli ECRC102 0.33 NIAGMN_10095 hflK FtsH protease activity modulator HflK 0.58 NIAGMN_24935 emrE multidrug efflux SMR transporter EmrE — —
Escherichia coli ECRC98 0.33 JDDGAC_15885 hflK FtsH protease activity modulator HflK 0.58 JDDGAC_06575 emrE multidrug efflux SMR transporter EmrE — —
Escherichia coli ECRC101 0.33 MCAODC_02760 hflK FtsH protease activity modulator HflK 0.58 MCAODC_14880 emrE multidrug efflux SMR transporter EmrE — —
Escherichia coli BW25113 0.33 b4174 hflK modulator for HflB protease specific for phage lambda cII repressor (NCBI) 0.58 b0543 emrE multidrug efflux protein (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.33 OHPLBJKB_03868 Modulator of FtsH protease HflK 0.58 OHPLBJKB_01793 Multidrug transporter EmrE low > 73
Escherichia coli ECOR27 0.33 NOLOHH_04510 hflK FtsH protease activity modulator HflK 0.32 NOLOHH_04635 sugE quaternary ammonium compound efflux SMR transporter SugE low > 57
Escherichia coli BL21 0.33 ECD_04041 modulator for HflB protease specific for phage lambda cII repressor 0.56 ECD_00493 DLP12 prophage; multidrug resistance protein — —
Dickeya dianthicola 67-19 0.33 HGI48_RS18535 FtsH protease activity modulator HflK 0.62 HGI48_RS06305 multidrug efflux SMR transporter low > 71
Serratia liquefaciens MT49 0.33 IAI46_01635 FtsH protease activity modulator HflK 0.62 IAI46_13370 QacE family quaternary ammonium compound efflux SMR transporter — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.33 GFF827 HflK protein 0.63 GFF2645 Ethidium bromide-methyl viologen resistance protein EmrE low > 78
Dickeya dianthicola ME23 0.33 DZA65_RS19670 FtsH protease activity modulator HflK 0.63 DZA65_RS06650 multidrug transporter low > 75
Dickeya dadantii 3937 0.33 DDA3937_RS18600 FtsH protease activity modulator HflK 0.62 DDA3937_RS06260 multidrug efflux SMR transporter low > 74
Enterobacter sp. TBS_079 0.33 MPMX20_00455 Modulator of FtsH protease HflK 0.34 MPMX20_00430 Guanidinium exporter low > 85
Pectobacterium carotovorum WPP14 0.32 HER17_RS02595 FtsH protease activity modulator HflK 0.55 HER17_RS07420 SMR family transporter low > 75
Pantoea sp. MT58 0.32 IAI47_02600 FtsH protease activity modulator HflK 0.28 IAI47_08635 multidrug/spermidine efflux SMR transporter subunit MdtI low > 76
Rahnella sp. WP5 0.32 EX31_RS08810 FtsH protease activity modulator HflK 0.56 EX31_RS02410 multidrug DMT transporter low > 89
Dechlorosoma suillum PS 0.30 Dsui_3135 HflK protein 0.66 Dsui_1837 cation/cationic drug transporter — —
Rhodospirillum rubrum S1H 0.29 Rru_A2203 HflK (NCBI) 0.44 Rru_A3353 Small multidrug resistance protein (NCBI) — —
Magnetospirillum magneticum AMB-1 0.29 AMB_RS17650 FtsH protease activity modulator HflK 0.25 AMB_RS06565 QacE family quaternary ammonium compound efflux SMR transporter — —
Cupriavidus basilensis FW507-4G11 0.28 RR42_RS13105 membrane protein 0.57 RR42_RS14705 multidrug transporter — —
Herbaspirillum seropedicae SmR1 0.28 HSERO_RS14765 membrane protein 0.63 HSERO_RS23145 multidrug transporter low > 78
Rhodanobacter denitrificans FW104-10B01 0.28 LRK54_RS00620 FtsH protease activity modulator HflK 0.34 LRK54_RS00480 quaternary ammonium compound efflux SMR transporter SugE low > 59
Hydrogenophaga sp. GW460-11-11-14-LB1 0.28 GFF4856 HflK protein 0.70 GFF4245 Ethidium bromide-methyl viologen resistance protein EmrE low > 90
Rhodanobacter denitrificans MT42 0.27 LRK55_RS00390 FtsH protease activity modulator HflK 0.34 LRK55_RS00220 quaternary ammonium compound efflux SMR transporter SugE low > 63
Paraburkholderia sabiae LMG 24235 0.27 QEN71_RS06010 FtsH protease activity modulator HflK 0.60 QEN71_RS22735 multidrug efflux SMR transporter low > 153
Rhodopseudomonas palustris CGA009 0.27 TX73_018080 FtsH protease activity modulator HflK 0.49 TX73_009120 multidrug efflux SMR transporter low > 86
Dinoroseobacter shibae DFL-12 0.26 Dshi_2736 HflK protein (RefSeq) 0.51 Dshi_1638 small multidrug resistance protein (RefSeq) low > 64
Ralstonia sp. UNC404CL21Col 0.26 ABZR87_RS10950 FtsH protease activity modulator HflK 0.29 ABZR87_RS21585 multidrug efflux SMR transporter low > 80
Phaeobacter inhibens DSM 17395 0.26 PGA1_c23710 putative protein HflK 0.52 PGA1_c15310 multidrug transporter EmrE low > 62
Lysobacter sp. OAE881 0.26 ABIE51_RS06550 FtsH protease activity modulator HflK 0.70 ABIE51_RS10570 SMR family transporter low > 62
Azospirillum sp. SherDot2 0.26 MPMX19_01251 Modulator of FtsH protease HflK 0.36 MPMX19_00112 Multidrug transporter EmrE — —
Acidovorax sp. GW101-3H11 0.26 Ac3H11_1801 HflK protein 0.67 Ac3H11_2948 Ethidium bromide-methyl viologen resistance protein EmrE low > 79
Bosea sp. OAE506 0.26 ABIE41_RS12850 FtsH protease activity modulator HflK 0.60 ABIE41_RS07290 SMR family transporter low > 77
Variovorax sp. SCN45 0.25 GFF1002 HflK protein 0.67 GFF2129 small multidrug resistance family (SMR) protein low > 127
Sinorhizobium meliloti 1021 0.25 SMc01441 membrane bound protease 0.56 SMc01523 methyl viologen/ethidium resistance transmembrane protein low > 103
Dyella japonica UNC79MFTsu3.2 0.25 ABZR86_RS08355 FtsH protease activity modulator HflK 0.33 ABZR86_RS08255 quaternary ammonium compound efflux SMR transporter SugE low > 74
Variovorax sp. OAS795 0.25 ABID97_RS14260 FtsH protease activity modulator HflK 0.32 ABID97_RS10520 quaternary ammonium compound efflux SMR transporter SugE low > 91
Xanthomonas campestris pv. campestris strain 8004 0.24 Xcc-8004.3955.1 HflK protein 0.63 Xcc-8004.2118.1 Ethidium bromide-methyl viologen resistance protein EmrE low > 74
Agrobacterium fabrum C58 0.24 Atu2045 HFLK protein 0.56 Atu2319 quaternary ammonium compound-resistance protein low > 89
Rhizobium sp. OAE497 0.23 ABIE40_RS11535 FtsH protease activity modulator HflK 0.58 ABIE40_RS14355 SMR family transporter low > 107
Sphingomonas koreensis DSMZ 15582 0.20 Ga0059261_1380 Membrane protease subunits, stomatin/prohibitin homologs 0.32 Ga0059261_0749 Membrane transporters of cations and cationic drugs low > 68

Not shown: 9 genomes with orthologs for HP15_2497 only; 13 genomes with orthologs for HP15_958 only