| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Sphingobium sp. HT1-2 | 1.0 | GFF5087 | | Zinc-type alcohol dehydrogenase-like protein | 1.0 | GFF683 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | 0.86 | 8 |
| Rhizobium sp. OAE497 | 0.66 | ABIE40_RS05835 | | zinc-binding alcohol dehydrogenase family protein | 0.18 | ABIE40_RS10550 | | fumarate hydratase | low | > 107 |
| Acinetobacter baumannii LAC-4 | 0.62 | RR41_RS16800 | | zinc-binding alcohol dehydrogenase family protein | 0.70 | RR41_RS16545 | | fumarate hydratase | low | > 55 |
| Azospirillum brasilense Sp245 | 0.61 | AZOBR_RS06765 | | NADPH:quinone reductase | 0.19 | AZOBR_RS10315 | | fumarate hydratase | — | — |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.60 | GFF2160 | | Bifunctional protein: zinc-containing alcohol dehydrogenase; quinone oxidoreductase ( NADPH:quinone reductase) (EC 1.1.1.-); Similar to arginate lyase | 0.69 | GFF4099 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | — | — |
| Acinetobacter radioresistens SK82 | 0.58 | MPMX26_00857 | | Zinc-type alcohol dehydrogenase-like protein | 0.70 | MPMX26_00411 | | Fumarate hydratase class I, aerobic | low | > 36 |
| Pseudomonas segetis P6 | 0.58 | MPMX49_01119 | | Zinc-type alcohol dehydrogenase-like protein | 0.68 | MPMX49_03729 | | Fumarate hydratase class I, anaerobic | — | — |
| Bosea sp. OAE506 | 0.57 | ABIE41_RS23570 | | zinc-binding alcohol dehydrogenase family protein | 0.17 | ABIE41_RS00110 | | fumarate hydratase | low | > 77 |
| Acidovorax sp. GW101-3H11 | 0.57 | Ac3H11_4512 | | Bifunctional protein: zinc-containing alcohol dehydrogenase; quinone oxidoreductase ( NADPH:quinone reductase) (EC 1.1.1.-); Similar to arginate lyase | 0.68 | Ac3H11_941 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | — | — |
| Ralstonia sp. UNC404CL21Col | 0.56 | ABZR87_RS05920 | | zinc-binding alcohol dehydrogenase family protein | 0.74 | ABZR87_RS14375 | | fumarate hydratase | low | > 80 |
| Pseudomonas putida KT2440 | 0.56 | PP_2953 | | Alcohol dehydrogenase, zinc-containing | 0.70 | PP_0897 | | Fumarate hydratase, class I | — | — |
| Pseudomonas fluorescens FW300-N2C3 | 0.56 | AO356_26600 | | NADPH:quinone reductase | 0.71 | AO356_17810 | | fumarate hydratase | — | — |
| Pseudomonas fluorescens FW300-N1B4 | 0.56 | Pf1N1B4_1257 | | Bifunctional protein: zinc-containing alcohol dehydrogenase; quinone oxidoreductase ( NADPH:quinone reductase) (EC 1.1.1.-); Similar to arginate lyase | 0.71 | Pf1N1B4_683 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | low | > 87 |
| Pseudomonas fluorescens FW300-N2E3 | 0.55 | AO353_06135 | | NADPH:quinone reductase | 0.72 | AO353_03795 | | fumarate hydratase | low | > 101 |
| Pseudomonas syringae pv. syringae B728a | 0.55 | Psyr_0658 | | Zinc-containing alcohol dehydrogenase superfamily | 0.71 | Psyr_4031 | | fumarase | — | — |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.55 | Psyr_0658 | | Zinc-containing alcohol dehydrogenase superfamily | 0.71 | Psyr_4031 | | fumarase | — | — |
| Pseudomonas sp. SVBP6 | 0.55 | COO64_RS26360 | | zinc-binding alcohol dehydrogenase family protein | 0.71 | COO64_RS12175 | | fumarate hydratase | — | — |
| Azospirillum sp. SherDot2 | 0.55 | MPMX19_00223 | | Zinc-type alcohol dehydrogenase-like protein | 0.18 | MPMX19_03166 | | Fumarate hydratase class I, aerobic | — | — |
| Pseudomonas sp. DMC3 | 0.55 | GFF3361 | | Zinc-type alcohol dehydrogenase-like protein | 0.71 | GFF5036 | | Fumarate hydratase class I, aerobic | — | — |
| Pseudomonas sp. S08-1 | 0.55 | OH686_07350 | | Zinc-type alcohol dehydrogenase-like protein | 0.71 | OH686_18780 | | Fumarate hydratase class I, aerobic | — | — |
| Pseudomonas aeruginosa PA14 | 0.55 | IKLFDK_18210 | | zinc-binding alcohol dehydrogenase family protein | 0.72 | IKLFDK_02440 | | fumarate hydratase | — | — |
| Pseudomonas sp. RS175 | 0.55 | PFR28_05249 | | Zinc-type alcohol dehydrogenase-like protein | 0.71 | PFR28_03458 | | Fumarate hydratase class I, aerobic | — | — |
| Rhodopseudomonas palustris CGA009 | 0.55 | TX73_016670 | | zinc-binding alcohol dehydrogenase family protein | 0.20 | TX73_020085 | | fumarate hydratase | low | > 86 |
| Burkholderia phytofirmans PsJN | 0.55 | BPHYT_RS27480 | | NADPH:quinone reductase | 0.72 | BPHYT_RS06985 | | fumarate hydratase | — | — |
| Pseudomonas fluorescens FW300-N2E2 | 0.54 | Pf6N2E2_3482 | | Bifunctional protein: zinc-containing alcohol dehydrogenase; quinone oxidoreductase ( NADPH:quinone reductase) (EC 1.1.1.-); Similar to arginate lyase | 0.71 | Pf6N2E2_5489 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | — | — |
| Pseudomonas fluorescens GW456-L13 | 0.54 | PfGW456L13_19 | | Bifunctional protein: zinc-containing alcohol dehydrogenase; quinone oxidoreductase ( NADPH:quinone reductase) (EC 1.1.1.-); Similar to arginate lyase | 0.72 | PfGW456L13_1808 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | — | — |
| Variovorax sp. SCN45 | 0.54 | GFF6904 | | Zinc-type alcohol dehydrogenase-like protein | 0.69 | GFF483 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | low | > 127 |
| Pseudomonas sp. BP01 | 0.54 | JOY50_RS03260 | | zinc-binding alcohol dehydrogenase family protein | 0.70 | JOY50_RS14310 | | fumarate hydratase | — | — |
| Herbaspirillum seropedicae SmR1 | 0.54 | HSERO_RS05430 | | NADPH:quinone reductase | 0.73 | HSERO_RS07760 | | fumarate hydratase | — | — |
| Xanthomonas campestris pv. campestris strain 8004 | 0.54 | Xcc-8004.5377.1 | | DNA recombination protein RmuC | 0.70 | Xcc-8004.3506.1 | | Fumarate hydratase class I, aerobic (EC 4.2.1.2) | — | — |
| Pseudomonas simiae WCS417 | 0.53 | PS417_03185 | | NADPH:quinone reductase | 0.72 | PS417_22635 | | fumarate hydratase | — | — |
| Klebsiella pneumoniae MKP103 | 0.53 | KDGMDA_08245 | | zinc-binding alcohol dehydrogenase family protein | 0.18 | KDGMDA_20935 | | class I fumarate hydratase FumA | low | > 95 |
| Pseudomonas fluorescens SBW25-INTG | 0.53 | PFLU_RS03265 | | zinc-binding alcohol dehydrogenase family protein | 0.72 | PFLU_RS24270 | | fumarate hydratase | — | — |
| Pseudomonas fluorescens SBW25 | 0.53 | PFLU_RS03265 | | zinc-binding alcohol dehydrogenase family protein | 0.72 | PFLU_RS24270 | | fumarate hydratase | — | — |
| Paraburkholderia bryophila 376MFSha3.1 | 0.53 | H281DRAFT_01721 | | zinc-binding alcohol dehydrogenase family protein | 0.73 | H281DRAFT_04956 | | fumarase, class I, homodimeric | — | — |
| Pseudomonas lactucae CFBP13502 | 0.53 | GEMAOFIL_00852 | | Zinc-type alcohol dehydrogenase-like protein | 0.70 | GEMAOFIL_04680 | | Fumarate hydratase class I, aerobic | low | > 93 |
| Pseudomonas stutzeri RCH2 | 0.53 | Psest_3828 | | zinc-binding alcohol dehydrogenase family protein | 0.71 | Psest_3193 | | hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region/hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region | — | — |
| Rhodospirillum rubrum S1H | 0.53 | Rru_A0088 | | Zinc-containing alcohol dehydrogenase superfamily (NCBI) | 0.19 | Rru_A2206 | | tartrate dehydrogenase (NCBI) | — | — |
| Alteromonas macleodii MIT1002 | 0.52 | MIT1002_02514 | | Zinc-type alcohol dehydrogenase-like protein | 0.67 | MIT1002_02009 | | Fumarate hydratase class I, anaerobic | — | — |
| Dyella japonica UNC79MFTsu3.2 | 0.52 | ABZR86_RS18125 | | zinc-binding alcohol dehydrogenase family protein | 0.71 | ABZR86_RS19555 | | fumarate hydratase | low | > 74 |
| Shewanella oneidensis MR-1 | 0.52 | SO0401 | | alcohol dehydrogenase, zinc-containing (NCBI ptt file) | 0.65 | SO2222 | | fumarate hydratase, class I, anaerobic, putative (NCBI ptt file) | — | — |
| Shewanella sp. ANA-3 | 0.51 | Shewana3_0406 | | alcohol dehydrogenase (RefSeq) | 0.65 | Shewana3_2302 | | fumarase (RefSeq) | — | — |
| Rhodanobacter sp000427505 FW510-R12 | 0.51 | LRK53_RS01755 | | zinc-binding alcohol dehydrogenase family protein | 0.71 | LRK53_RS15950 | | fumarate hydratase | low | > 59 |
| Variovorax sp. OAS795 | 0.51 | ABID97_RS05565 | | zinc-binding alcohol dehydrogenase family protein | 0.69 | ABID97_RS17550 | | fumarate hydratase | low | > 91 |
| Klebsiella michiganensis M5al | 0.51 | BWI76_RS27625 | | NADPH:quinone reductase | 0.17 | BWI76_RS16115 | | fumarate hydratase | low | > 92 |
| Paraburkholderia graminis OAS925 | 0.51 | ABIE53_005668 | | NADPH2:quinone reductase | 0.73 | ABIE53_001662 | | fumarate hydratase class I | low | > 113 |
| Rhodanobacter sp. FW510-T8 | 0.51 | OKGIIK_16975 | qor | zinc-binding alcohol dehydrogenase family protein | 0.70 | OKGIIK_02115 | ttdA | fumarate hydratase | low | > 53 |
| Cupriavidus basilensis FW507-4G11 | 0.51 | RR42_RS34125 | | NADPH:quinone reductase | 0.75 | RR42_RS13905 | | fumarate hydratase | low | > 128 |
| Rhodanobacter denitrificans MT42 | 0.50 | LRK55_RS06410 | | zinc-binding alcohol dehydrogenase family protein | 0.71 | LRK55_RS12360 | | fumarate hydratase | low | > 63 |
| Rhodanobacter denitrificans FW104-10B01 | 0.50 | LRK54_RS06665 | | zinc-binding alcohol dehydrogenase family protein | 0.71 | LRK54_RS12620 | | fumarate hydratase | low | > 59 |
| Lysobacter sp. OAE881 | 0.49 | ABIE51_RS06075 | | zinc-binding alcohol dehydrogenase family protein | 0.72 | ABIE51_RS12620 | | fumarate hydratase | low | > 62 |
| Paraburkholderia sabiae LMG 24235 | 0.49 | QEN71_RS22130 | | zinc-binding alcohol dehydrogenase family protein | 0.72 | QEN71_RS23780 | | fumarate hydratase | low | > 153 |
| Rahnella sp. WP5 | 0.42 | EX31_RS04010 | | zinc-binding alcohol dehydrogenase family protein | 0.18 | EX31_RS01160 | | fumarate hydratase | low | > 89 |
| Pantoea agglomerans CFBP13505 P0401 | 0.42 | PagCFBP13505_RS21765 | | zinc-binding alcohol dehydrogenase family protein | 0.18 | PagCFBP13505_RS13945 | | fumarate hydratase | low | > 74 |
| Pantoea sp. MT58 | 0.42 | IAI47_16335 | | zinc-binding alcohol dehydrogenase family protein | 0.17 | IAI47_20435 | | fumarate hydratase | low | > 76 |
| Erwinia amylovora T8 | 0.41 | OLJFJH_01565 | | zinc-binding alcohol dehydrogenase family protein | 0.18 | OLJFJH_15150 | | class I fumarate hydratase FumA | low | > 58 |
| Serratia liquefaciens MT49 | 0.41 | IAI46_02955 | | zinc-binding alcohol dehydrogenase family protein | 0.18 | IAI46_21370 | | fumarate hydratase | low | > 86 |
| Enterobacter sp. TBS_079 | 0.40 | MPMX20_00696 | | Zinc-type alcohol dehydrogenase-like protein | 0.18 | MPMX20_02021 | | Fumarate hydratase class I, aerobic | low | > 85 |
| Dickeya dadantii 3937 | 0.39 | DDA3937_RS18475 | | zinc-binding alcohol dehydrogenase family protein | 0.17 | DDA3937_RS04540 | | fumarate hydratase | low | > 74 |
| Enterobacter asburiae PDN3 | 0.39 | EX28DRAFT_3599 | | zinc-binding alcohol dehydrogenase family protein | 0.18 | EX28DRAFT_1609 | | hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha region/hydro-lyases, Fe-S type, tartrate/fumarate subfamily, beta region | low | > 76 |
| Pectobacterium carotovorum WPP14 | 0.37 | HER17_RS02730 | | zinc-binding alcohol dehydrogenase family protein | 0.17 | HER17_RS17120 | | fumarate hydratase | low | > 75 |
Not shown: 5 genomes with orthologs for GFF5087 only; 38 genomes with orthologs for GFF683 only