Conservation of cofitness between GFF4211 and GFF652 in Hydrogenophaga sp. GW460-11-11-14-LB1

53 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Hydrogenophaga sp. GW460-11-11-14-LB1 1.0 GFF4211 Dihydroorotate dehydrogenase (EC 1.3.3.1) 1.0 GFF652 Dihydroorotase (EC 3.5.2.3) 0.84 5
Variovorax sp. OAS795 0.74 ABID97_RS14065 quinone-dependent dihydroorotate dehydrogenase 0.67 ABID97_RS24655 dihydroorotase — —
Acidovorax sp. GW101-3H11 0.74 Ac3H11_4100 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.73 Ac3H11_3977 Dihydroorotase (EC 3.5.2.3) — —
Variovorax sp. SCN45 0.73 GFF960 Dihydroorotate dehydrogenase (quinone) (EC 1.3.5.2) 0.64 GFF2161 Dihydroorotase (EC 3.5.2.3) — —
Ralstonia sp. UNC404CL21Col 0.56 ABZR87_RS13360 quinone-dependent dihydroorotate dehydrogenase 0.62 ABZR87_RS08630 dihydroorotase — —
Ralstonia solanacearum IBSBF1503 0.55 RALBFv3_RS01570 quinone-dependent dihydroorotate dehydrogenase 0.62 RALBFv3_RS12630 dihydroorotase — —
Ralstonia solanacearum UW163 0.55 UW163_RS14880 quinone-dependent dihydroorotate dehydrogenase 0.62 UW163_RS00935 dihydroorotase — —
Herbaspirillum seropedicae SmR1 0.55 HSERO_RS16155 dihydroorotate dehydrogenase 0.60 HSERO_RS02340 dihydroorotase — —
Ralstonia solanacearum PSI07 0.55 RPSI07_RS15920 quinone-dependent dihydroorotate dehydrogenase 0.61 RPSI07_RS20630 dihydroorotase — —
Ralstonia solanacearum GMI1000 0.55 RS_RS08160 dihydroorotate dehydrogenase (quinone) 0.61 RS_RS03415 dihydroorotase — —
Burkholderia phytofirmans PsJN 0.53 BPHYT_RS08565 dihydroorotate dehydrogenase 0.63 BPHYT_RS04245 dihydroorotase low > 109
Paraburkholderia sabiae LMG 24235 0.53 QEN71_RS22765 quinone-dependent dihydroorotate dehydrogenase 0.63 QEN71_RS25775 dihydroorotase — —
Cupriavidus basilensis FW507-4G11 0.53 RR42_RS07465 dihydroorotate dehydrogenase 0.60 RR42_RS15855 dihydroorotase — —
Paraburkholderia graminis OAS925 0.53 ABIE53_001954 dihydroorotate dehydrogenase 0.62 ABIE53_001133 dihydroorotase — —
Dechlorosoma suillum PS 0.51 Dsui_2978 dihydroorotate dehydrogenase, subfamily 2 0.45 Dsui_0597 dihydroorotase, multifunctional complex type — —
Paraburkholderia bryophila 376MFSha3.1 0.51 H281DRAFT_00743 dihydroorotate oxidase A 0.63 H281DRAFT_04818 dihydroorotase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.49 Psyr_2106 dihydroorotate oxidase A 0.38 Psyr_0481 dihydroorotase — —
Pseudomonas syringae pv. syringae B728a 0.49 Psyr_2106 dihydroorotate oxidase A 0.38 Psyr_0481 dihydroorotase — —
Pseudomonas fluorescens SBW25 0.48 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.38 PFLU_RS28350 dihydroorotase — —
Pseudomonas fluorescens SBW25-INTG 0.48 PFLU_RS22550 quinone-dependent dihydroorotate dehydrogenase 0.38 PFLU_RS28350 dihydroorotase — —
Pseudomonas simiae WCS417 0.48 PS417_20935 dihydroorotate dehydrogenase 0.38 PS417_26705 dihydroorotase — —
Pseudomonas putida KT2440 0.48 PP_2095 Dihydroorotate dehydrogenase (quinone) 0.38 PP_4999 dihydroorotase-like protein — —
Pseudomonas stutzeri RCH2 0.48 Psest_1947 dihydroorotate dehydrogenase, subfamily 2 0.37 Psest_0290 dihydroorotase, multifunctional complex type — —
Pseudomonas sp. RS175 0.48 PFR28_01054 Dihydroorotate dehydrogenase (quinone) 0.37 PFR28_04238 Dihydroorotase-like protein — —
Pseudomonas fluorescens GW456-L13 0.48 PfGW456L13_4095 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.38 PfGW456L13_1015 Dihydroorotase (EC 3.5.2.3) — —
Pseudomonas fluorescens FW300-N1B4 0.47 Pf1N1B4_3842 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.38 Pf1N1B4_2346 Dihydroorotase (EC 3.5.2.3) — —
Pseudomonas fluorescens FW300-N2E2 0.47 Pf6N2E2_2347 Dihydroorotate dehydrogenase (EC 1.3.3.1) 0.37 Pf6N2E2_4605 Dihydroorotase (EC 3.5.2.3) — —
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_00780 dihydroorotate dehydrogenase (quinone) 0.37 AO353_08140 dihydroorotase — —
Acinetobacter radioresistens SK82 0.47 MPMX26_01120 Dihydroorotate dehydrogenase (quinone) 0.24 MPMX26_01100 Dihydroorotase-like protein 0.98 2
Pseudomonas fluorescens FW300-N2C3 0.47 AO356_02610 dihydroorotate dehydrogenase (quinone) 0.37 AO356_13445 dihydroorotase — —
Pseudomonas sp. S08-1 0.46 OH686_03120 dihydroorotate dehydrogenase (fumarate) 0.36 OH686_10945 Dihydroorotase — —
Marinobacter adhaerens HP15 0.45 HP15_1377 dihydroorotate dehydrogenase 0.31 HP15_3506 dihydroorotase, multifunctional complex type 0.79 1
Echinicola vietnamensis KMM 6221, DSM 17526 0.40 Echvi_1806 dihydroorotate dehydrogenase, subfamily 2 0.21 Echvi_4623 Dihydroorotase and related cyclic amidohydrolases — —
Agrobacterium fabrum C58 0.39 Atu0486 dihydroorotate dehydrogenase 0.28 Atu1307 dihydroorotase 0.92 5
Pontibacter actiniarum KMM 6156, DSM 19842 0.38 CA264_00865 dihydroorotate dehydrogenase (quinone) 0.26 CA264_01480 dihydroorotase low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.37 ABZR88_RS12040 quinone-dependent dihydroorotate dehydrogenase 0.24 ABZR88_RS07940 dihydroorotase family protein — —
Pedobacter sp. GW460-11-11-14-LB5 0.37 CA265_RS14005 dihydroorotate dehydrogenase (quinone) 0.22 CA265_RS03710 dihydroorotase — —
Sinorhizobium meliloti 1021 0.37 SMc02245 dihydroorotate dehydrogenase 2 0.29 SMc01361 dihydroorotase 0.79 64
Azospirillum brasilense Sp245 0.36 AZOBR_RS13520 dihydroorotate dehydrogenase 0.32 AZOBR_RS20570 dihydroorotase — —
Azospirillum sp. SherDot2 0.35 MPMX19_02083 Dihydroorotate dehydrogenase (quinone) 0.31 MPMX19_01053 Dihydroorotase — —
Phaeobacter inhibens DSM 17395 0.35 PGA1_c12150 dihydroorotate dehydrogenase PyrD 0.28 PGA1_c03020 dihydroorotase PyrC 0.96 3
Rhizobium sp. OAE497 0.35 ABIE40_RS02420 quinone-dependent dihydroorotate dehydrogenase 0.29 ABIE40_RS07380 dihydroorotase — —
Brevundimonas sp. GW460-12-10-14-LB2 0.34 A4249_RS00280 quinone-dependent dihydroorotate dehydrogenase 0.31 A4249_RS04255 dihydroorotase — —
Sphingomonas koreensis DSMZ 15582 0.34 Ga0059261_1468 dihydroorotate oxidase A (EC 1.3.3.1) 0.21 Ga0059261_0075 Dihydroorotase and related cyclic amidohydrolases — —
Dinoroseobacter shibae DFL-12 0.33 Dshi_0847 Dihydroorotate oxidase (RefSeq) 0.23 Dshi_3094 dihydroorotase, multifunctional complex type (RefSeq) 0.81 10
Rhodospirillum rubrum S1H 0.33 Rru_A0514 Dihydroorotate dehydrogenase 2 (NCBI) 0.32 Rru_A3191 Dihydroorotase multifunctional complex type (NCBI) 0.88 8
Caulobacter crescentus NA1000 0.32 CCNA_00562 dihydroorotate dehydrogenase 0.28 CCNA_02526 dihydroorotase 0.96 3
Bosea sp. OAE506 0.32 ABIE41_RS24065 quinone-dependent dihydroorotate dehydrogenase 0.31 ABIE41_RS17225 dihydroorotase — —
Caulobacter crescentus NA1000 Δfur 0.32 CCNA_00562 dihydroorotate dehydrogenase 0.28 CCNA_02526 dihydroorotase 0.72 11
Magnetospirillum magneticum AMB-1 0.32 AMB_RS19685 quinone-dependent dihydroorotate dehydrogenase 0.35 AMB_RS18295 dihydroorotase — —
Rhodopseudomonas palustris CGA009 0.30 TX73_004110 quinone-dependent dihydroorotate dehydrogenase 0.30 TX73_016125 dihydroorotase — —
Synechococcus elongatus PCC 7942 0.30 Synpcc7942_0290 pyrD dihydroorotate dehydrogenase 2 0.18 Synpcc7942_0486 pyrC dihydroorotase — —
Mycobacterium tuberculosis H37Rv 0.27 Rv2139 Probable dihydroorotate dehydrogenase PyrD 0.24 Rv1381 Probable dihydroorotase PyrC (DHOase) — —
Bifidobacterium breve UCC2003 0.18 BBR_RS12895 quinone-dependent dihydroorotate dehydrogenase 0.15 BBR_RS15435 dihydroorotase low > 34

Not shown: 42 genomes with orthologs for GFF4211 only; 2 genomes with orthologs for GFF652 only