Conservation of cofitness between ECD_03708 and ECD_03078 in Escherichia coli BL21

61 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_03708 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 1.0 ECD_03078 glutamate synthase, 4Fe-4S protein, small subunit low > 61
Escherichia coli Nissle 1917 1.00 ECOLIN_RS21980 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 1.00 ECOLIN_RS18480 glutamate synthase subunit GltD low > 55
Escherichia coli BW25113 1.00 b3829 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (NCBI) 1.00 b3213 gltD glutamate synthase, 4Fe-4S protein, small subunit (NCBI) low > 76
Escherichia fergusonii Becca 1.00 EFB2_04808 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1.00 EFB2_00610 Glutamate synthase [NADPH] small chain low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_04222 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 1.00 OHPLBJKB_00487 Glutamate synthase [NADPH] small chain low > 73
Escherichia coli ECOR27 0.99 NOLOHH_06455 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 1.00 NOLOHH_09680 gltD glutamate synthase subunit GltD 0.82 49
Escherichia coli ECRC62 0.99 BNILDI_05075 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 BNILDI_01855 gltD glutamate synthase subunit GltD 0.91 65
Escherichia coli ECOR38 0.99 HEPCGN_13025 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 HEPCGN_16755 gltD glutamate synthase subunit GltD 0.94 48
Escherichia coli ECRC100 0.99 OKFHMN_14325 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 OKFHMN_17880 gltD glutamate synthase subunit GltD 0.88 67
Escherichia coli ECRC99 0.99 KEDOAH_13825 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 KEDOAH_10270 gltD glutamate synthase subunit GltD
Escherichia coli ECRC101 0.99 MCAODC_04830 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 MCAODC_08400 gltD glutamate synthase subunit GltD low > 87
Escherichia coli ECRC98 0.99 JDDGAC_17950 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 JDDGAC_21505 gltD glutamate synthase subunit GltD low > 86
Escherichia coli ECRC102 0.99 NIAGMN_12080 metE 5-methyltetrahydropteroyltriglutamate--homocystei ne S-methyltransferase 0.99 NIAGMN_15640 gltD glutamate synthase subunit GltD
Enterobacter asburiae PDN3 0.95 EX28DRAFT_4494 methionine synthase (B12-independent) (EC 2.1.1.14) 0.95 EX28DRAFT_3276 glutamate synthase small subunit family protein, proteobacterial 0.82 4
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.94 GFF254 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.96 GFF2957 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) low > 78
Klebsiella michiganensis M5al 0.94 BWI76_RS01280 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.95 BWI76_RS25320 glutamate synthase 0.27 47
Enterobacter sp. TBS_079 0.94 MPMX20_04451 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.95 MPMX20_04127 Glutamate synthase [NADPH] small chain low > 85
Pectobacterium carotovorum WPP14 0.86 HER17_RS20685 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.88 HER17_RS19915 glutamate synthase small subunit low > 75
Dickeya dadantii 3937 0.85 DDA3937_RS20380 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.89 DDA3937_RS01660 FAD-dependent oxidoreductase 0.49 44
Dickeya dianthicola ME23 0.85 DZA65_RS00875 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.88 DZA65_RS01630 FAD-dependent oxidoreductase 0.43 65
Dickeya dianthicola 67-19 0.85 HGI48_RS00820 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.89 HGI48_RS01555 glutamate synthase small subunit low > 71
Erwinia tracheiphila SCR3 0.84 LU632_RS24030 metE 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.90 LU632_RS21320 glutamate synthase small subunit low > 74
Serratia liquefaciens MT49 0.84 IAI46_01035 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.87 IAI46_22350 glutamate synthase small subunit 0.69 40
Rahnella sp. WP5 0.83 EX31_RS14710 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.88 EX31_RS12510 FAD-dependent oxidoreductase low > 89
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_5472 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.69 Pf6N2E2_3751 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) low > 103
Pseudomonas fluorescens FW300-N1B4 0.62 Pf1N1B4_783 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.68 Pf1N1B4_1533 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) low > 87
Pseudomonas sp. RS175 0.61 PFR28_03477 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.69 PFR28_05016 Glutamate synthase [NADPH] small chain low > 88
Pseudomonas fluorescens FW300-N2E3 0.61 AO353_16215 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.68 AO353_12520 glutamate synthase low > 101
Pseudomonas fluorescens FW300-N2C3 0.61 AO356_17740 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.69 AO356_09370 glutamate synthase low > 104
Pseudomonas stutzeri RCH2 0.60 Psest_1452 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 0.69 Psest_3710 glutamate synthase small subunit family protein, proteobacterial low > 67
Vibrio cholerae E7946 ATCC 55056 0.60 CSW01_08575 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.75 CSW01_12035 glutamate synthase small subunit low > 62
Pseudomonas fluorescens GW456-L13 0.59 PfGW456L13_3767 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.68 PfGW456L13_271 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) low > 87
Pseudomonas fluorescens SBW25 0.59 PFLU_RS17405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.68 PFLU_RS02050 NAD(P)-binding protein low > 109
Pseudomonas fluorescens SBW25-INTG 0.59 PFLU_RS17405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.68 PFLU_RS02050 NAD(P)-binding protein low > 109
Castellaniella sp019104865 MT123 0.59 ABCV34_RS04445 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.26 ABCV34_RS11155 glutamate synthase subunit beta low > 48
Pseudomonas sp. S08-1 0.59 OH686_20470 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.69 OH686_10000 Glutamate synthase [NADPH] small chain low > 80
Paraburkholderia sabiae LMG 24235 0.57 QEN71_RS19725 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.25 QEN71_RS28005 glutamate synthase subunit beta low > 153
Ralstonia sp. UNC404CL21Col 0.56 ABZR87_RS20880 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.26 ABZR87_RS02565 glutamate synthase subunit beta low > 80
Ralstonia solanacearum PSI07 0.55 RPSI07_RS02545 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.25 RPSI07_RS10325 glutamate synthase subunit beta 0.57 78
Acidovorax sp. GW101-3H11 0.55 Ac3H11_2345 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (EC 2.1.1.14) 0.26 Ac3H11_4711 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) 0.69 55
Ralstonia solanacearum GMI1000 0.55 RS_RS20360 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.25 RS_RS14855 glutamate synthase subunit beta 0.70 19
Ralstonia solanacearum UW163 0.55 UW163_RS18855 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.25 UW163_RS06705 glutamate synthase subunit beta
Ralstonia solanacearum IBSBF1503 0.55 RALBFv3_RS20320 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.25 RALBFv3_RS06910 glutamate synthase subunit beta low > 76
Shewanella sp. ANA-3 0.55 Shewana3_3469 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.69 Shewana3_3051 gltD glutamate synthase subunit beta (RefSeq) low > 73
Variovorax sp. SCN45 0.55 GFF795 5-methyltetrahydropteroyltriglutamate--homocystei ne methyltransferase (EC 2.1.1.14) 0.24 GFF5333 Glutamate synthase [NADPH] small chain (EC 1.4.1.13) low > 127
Shewanella loihica PV-4 0.55 Shew_2986 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase (RefSeq) 0.69 Shew_1031 gltD glutamate synthase subunit beta (RefSeq) low > 60
Shewanella oneidensis MR-1 0.55 SO0818 metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (NCBI ptt file) 0.69 SO1324 gltD glutamate synthase, small subunit (NCBI ptt file) 0.85 72
Marinobacter adhaerens HP15 0.54 HP15_457 5-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase 0.67 HP15_483 oxidoreductase Fe-S binding subunit
Mucilaginibacter yixingensis YX-36 DSM 26809 0.53 ABZR88_RS18615 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.23 ABZR88_RS06910 glutamate synthase subunit beta
Pedobacter sp. GW460-11-11-14-LB5 0.53 CA265_RS21095 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.26 CA265_RS08705 glutamate synthase low > 88
Cupriavidus basilensis FW507-4G11 0.53 RR42_RS30660 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.26 RR42_RS18985 glutamate synthase 0.65 36
Shewanella amazonensis SB2B 0.53 Sama_2627 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase (RefSeq) 0.69 Sama_0856 gltD glutamate synthase subunit beta (RefSeq) low > 62
Variovorax sp. OAS795 0.52 ABID97_RS19395 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.26 ABID97_RS23220 glutamate synthase subunit beta low > 91
Rhodopseudomonas palustris CGA009 0.52 TX73_012380 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.26 TX73_004595 glutamate synthase subunit beta
Caulobacter crescentus NA1000 Δfur 0.52 CCNA_00515 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.38 CCNA_03721 glutamate synthase (NADPH) small chain GltD low > 67
Caulobacter crescentus NA1000 0.52 CCNA_00515 5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase 0.38 CCNA_03721 glutamate synthase (NADPH) small chain GltD 0.90 50
Echinicola vietnamensis KMM 6221, DSM 17526 0.51 Echvi_2559 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase 0.22 Echvi_1243 glutamate synthases, NADH/NADPH, small subunit low > 79
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS03225 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.54 ABZR86_RS16800 FAD-dependent oxidoreductase low > 74
Rhodanobacter denitrificans FW104-10B01 0.49 LRK54_RS12135 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.55 LRK54_RS10965 FAD-dependent oxidoreductase low > 59
Rhodanobacter denitrificans MT42 0.49 LRK55_RS11870 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.55 LRK55_RS10670 FAD-dependent oxidoreductase low > 63
Mycobacterium tuberculosis H37Rv 0.45 Rv1133c Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MetE (methionine synthase, vitamin-B12 independent isozyme) 0.25 Rv3858c Probable NADH-dependent glutamate synthase (small subunit) GltD (L-glutamate synthase) (L-glutamate synthetase) (NADH-glutamate synthase) (glutamate synthase (NADH)) (GLTS beta chain) (NADPH-GOGAT)
Bifidobacterium breve UCC2003 0.42 BBR_RS15405 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase 0.27 BBR_RS15260 glutamate synthase subunit beta low > 34

Not shown: 6 genomes with orthologs for ECD_03708 only; 22 genomes with orthologs for ECD_03078 only