Conservation of cofitness between ECD_00373 and ECD_01825 in Escherichia coli BL21

62 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BL21 1.0 ECD_00373 2-dehydropantoate reductase, NADPH-specific 1.0 ECD_01825 pyruvate kinase II 0.50 9
Escherichia coli BW25113 1.00 b0425 panE 2-dehydropantoate 2-reductase (NCBI) 1.00 b1854 pykA pyruvate kinase (NCBI) 0.29 3
Escherichia fergusonii Becca 1.00 EFB2_03632 2-dehydropantoate 2-reductase 1.00 EFB2_02088 Pyruvate kinase II low > 86
Escherichia coli ECOR38 1.00 HEPCGN_07025 panE 2-dehydropantoate 2-reductase 1.00 HEPCGN_04725 pyk pyruvate kinase low > 87
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_03251 2-dehydropantoate 2-reductase 1.00 OHPLBJKB_01874 Pyruvate kinase II low > 73
Escherichia coli ECRC62 0.99 BNILDI_22760 panE 2-dehydropantoate 2-reductase 1.00 BNILDI_15630 pyk pyruvate kinase low > 75
Escherichia coli ECOR27 0.99 NOLOHH_01345 panE 2-dehydropantoate 2-reductase 1.00 NOLOHH_16835 pyk pyruvate kinase low > 75
Escherichia coli ECRC101 0.99 MCAODC_27620 panE 2-dehydropantoate 2-reductase 1.00 MCAODC_19085 pyk pyruvate kinase low > 87
Escherichia coli ECRC100 0.99 OKFHMN_08395 panE 2-dehydropantoate 2-reductase 1.00 OKFHMN_26320 pyk pyruvate kinase low > 80
Escherichia coli ECRC102 0.99 NIAGMN_06450 panE 2-dehydropantoate 2-reductase 1.00 NIAGMN_01740 pyk pyruvate kinase — —
Escherichia coli ECRC98 0.99 JDDGAC_12050 panE 2-dehydropantoate 2-reductase 1.00 JDDGAC_00895 pyk pyruvate kinase low > 86
Escherichia coli ECRC99 0.99 KEDOAH_19570 panE 2-dehydropantoate 2-reductase 1.00 KEDOAH_01785 pyk pyruvate kinase — —
Escherichia coli Nissle 1917 0.99 ECOLIN_RS02560 2-dehydropantoate 2-reductase 1.00 ECOLIN_RS10330 pyruvate kinase low > 55
Enterobacter sp. TBS_079 0.86 MPMX20_01016 2-dehydropantoate 2-reductase 0.98 MPMX20_02759 Pyruvate kinase II low > 85
Enterobacter asburiae PDN3 0.85 EX28DRAFT_2546 2-dehydropantoate 2-reductase 0.98 EX28DRAFT_0702 pyruvate kinase low > 76
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.81 GFF4336 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.99 GFF1633 Pyruvate kinase (EC 2.7.1.40) low > 78
Klebsiella michiganensis M5al 0.79 BWI76_RS06405 2-dehydropantoate 2-reductase 0.97 BWI76_RS18115 pyruvate kinase low > 92
Pantoea sp. MT58 0.66 IAI47_14715 2-dehydropantoate 2-reductase 0.93 IAI47_08485 pyruvate kinase 0.25 34
Serratia liquefaciens MT49 0.66 IAI46_04950 2-dehydropantoate 2-reductase 0.93 IAI46_14585 pyruvate kinase low > 86
Pectobacterium carotovorum WPP14 0.62 HER17_RS15910 2-dehydropantoate 2-reductase 0.92 HER17_RS11790 pyruvate kinase low > 75
Erwinia tracheiphila SCR3 0.61 LU632_RS18455 panE 2-dehydropantoate 2-reductase 0.92 LU632_RS13370 pyk pyruvate kinase low > 74
Dickeya dianthicola ME23 0.60 DZA65_RS05940 2-dehydropantoate 2-reductase 0.90 DZA65_RS10570 pyruvate kinase low > 75
Dickeya dianthicola 67-19 0.59 HGI48_RS05615 2-dehydropantoate 2-reductase 0.90 HGI48_RS10155 pyruvate kinase low > 71
Dickeya dadantii 3937 0.59 DDA3937_RS05555 2-dehydropantoate 2-reductase 0.90 DDA3937_RS10125 pyruvate kinase low > 74
Rahnella sp. WP5 0.58 EX31_RS22180 2-dehydropantoate 2-reductase 0.93 EX31_RS10640 pyruvate kinase low > 89
Vibrio cholerae E7946 ATCC 55056 0.34 CSW01_11730 2-dehydropantoate 2-reductase 0.68 CSW01_10025 pyruvate kinase low > 62
Pseudomonas stutzeri RCH2 0.24 Psest_1140 2-dehydropantoate 2-reductase 0.53 Psest_3190 pyruvate kinase low > 67
Pseudomonas sp. S08-1 0.23 OH686_08220 2-dehydropantoate 2-reductase 0.52 OH686_18800 pyruvate kinase low > 80
Pseudomonas fluorescens FW300-N2C3 0.23 AO356_17955 2-dehydropantoate 2-reductase 0.54 AO356_17830 pyruvate kinase low > 104
Pseudomonas fluorescens FW300-N2E2 0.23 Pf6N2E2_5521 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.54 Pf6N2E2_5494 Pyruvate kinase (EC 2.7.1.40) low > 103
Pseudomonas sp. RS175 0.23 PFR28_03426 2-dehydropantoate 2-reductase 0.54 PFR28_03455 Pyruvate kinase II low > 88
Pseudomonas fluorescens GW456-L13 0.23 PfGW456L13_1839 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.54 PfGW456L13_1813 Pyruvate kinase (EC 2.7.1.40) low > 87
Pseudomonas fluorescens SBW25-INTG 0.22 PFLU_RS24155 putative 2-dehydropantoate 2-reductase 0.54 PFLU_RS24255 pyruvate kinase low > 109
Pseudomonas fluorescens SBW25 0.22 PFLU_RS24155 putative 2-dehydropantoate 2-reductase 0.54 PFLU_RS24255 pyruvate kinase low > 109
Pseudomonas simiae WCS417 0.22 PS417_22515 2-dehydropantoate 2-reductase 0.54 PS417_22620 pyruvate kinase low > 88
Pseudomonas fluorescens FW300-N2E3 0.22 AO353_03645 2-dehydropantoate 2-reductase 0.54 AO353_03775 pyruvate kinase low > 101
Pseudomonas putida KT2440 0.22 PP_1351 putative 2-dehydropantoate 2-reductase 0.54 PP_1362 pyruvate kinase II low > 96
Pseudomonas fluorescens FW300-N1B4 0.22 Pf1N1B4_651 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.54 Pf1N1B4_678 Pyruvate kinase (EC 2.7.1.40) low > 87
Alteromonas macleodii MIT1002 0.21 MIT1002_01217 2-dehydropantoate 2-reductase 0.67 MIT1002_02409 Pyruvate kinase II — —
Shewanella sp. ANA-3 0.21 Shewana3_0780 2-dehydropantoate 2-reductase (RefSeq) 0.70 Shewana3_2153 pyruvate kinase (RefSeq) low > 73
Marinobacter adhaerens HP15 0.21 HP15_1312 2-dehydropantoate 2-reductase 0.57 HP15_2176 pyruvate kinase II low > 73
Shewanella loihica PV-4 0.20 Shew_2895 2-dehydropantoate 2-reductase (RefSeq) 0.69 Shew_2050 pyruvate kinase (RefSeq) — —
Shewanella oneidensis MR-1 0.20 SO3817 panE 2-dehydropantoate 2-reductase (NCBI ptt file) 0.69 SO2491 pykA pyruvate kinase II (NCBI ptt file) low > 76
Pseudomonas syringae pv. syringae B728a ΔmexB 0.20 Psyr_4088 ketopantoate reductase 0.53 Psyr_4029 pyruvate kinase low > 86
Pseudomonas syringae pv. syringae B728a 0.20 Psyr_4088 ketopantoate reductase 0.53 Psyr_4029 pyruvate kinase low > 86
Shewanella amazonensis SB2B 0.19 Sama_2559 2-dehydropantoate 2-reductase (RefSeq) 0.70 Sama_1814 pyruvate kinase (RefSeq) — —
Herbaspirillum seropedicae SmR1 0.17 HSERO_RS09230 2-dehydropantoate 2-reductase 0.45 HSERO_RS03350 hypothetical protein low > 78
Ralstonia sp. UNC404CL21Col 0.15 ABZR87_RS15450 2-dehydropantoate 2-reductase 0.45 ABZR87_RS08070 pyruvate kinase low > 80
Rhodopseudomonas palustris CGA009 0.14 TX73_023700 2-dehydropantoate 2-reductase 0.31 TX73_021735 pyruvate kinase — —
Variovorax sp. OAS795 0.14 ABID97_RS00870 2-dehydropantoate 2-reductase 0.45 ABID97_RS01755 pyruvate kinase low > 91
Variovorax sp. SCN45 0.14 GFF3590 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.46 GFF5504 Pyruvate kinase (EC 2.7.1.40) low > 127
Paraburkholderia sabiae LMG 24235 0.14 QEN71_RS38425 ketopantoate reductase family protein 0.47 QEN71_RS02430 pyruvate kinase low > 153
Cupriavidus basilensis FW507-4G11 0.12 RR42_RS32960 2-dehydropantoate 2-reductase 0.45 RR42_RS03210 pyruvate kinase low > 128
Acidovorax sp. GW101-3H11 0.12 Ac3H11_2346 2-dehydropantoate 2-reductase (EC 1.1.1.169) 0.44 Ac3H11_654 Pyruvate kinase (EC 2.7.1.40) low > 79
Burkholderia phytofirmans PsJN 0.12 BPHYT_RS27355 2-dehydropantoate 2-reductase 0.47 BPHYT_RS16265 hypothetical protein low > 109
Paraburkholderia bryophila 376MFSha3.1 0.11 H281DRAFT_01683 ketopantoate reductase (EC 1.1.1.169) 0.47 H281DRAFT_04189 pyruvate kinase low > 103
Paraburkholderia graminis OAS925 0.10 ABIE53_004184 2-dehydropantoate 2-reductase 0.47 ABIE53_003427 pyruvate kinase low > 113
Rhodanobacter denitrificans MT42 0.09 LRK55_RS02820 2-dehydropantoate 2-reductase 0.47 LRK55_RS05530 pyruvate kinase low > 63
Rhodanobacter denitrificans FW104-10B01 0.09 LRK54_RS03070 2-dehydropantoate 2-reductase 0.47 LRK54_RS05775 pyruvate kinase low > 59
Ralstonia solanacearum GMI1000 0.09 RS_RS00860 2-dehydropantoate 2-reductase 0.45 RS_RS02865 pyruvate kinase low > 80
Rhodanobacter sp. FW510-T8 0.09 OKGIIK_09940 panE 2-dehydropantoate 2-reductase 0.47 OKGIIK_01070 pyk pyruvate kinase low > 52
Ralstonia solanacearum IBSBF1503 0.08 RALBFv3_RS10240 2-dehydropantoate 2-reductase 0.45 RALBFv3_RS12180 pyruvate kinase low > 76
Ralstonia solanacearum UW163 0.08 UW163_RS03340 2-dehydropantoate 2-reductase 0.45 UW163_RS01430 pyruvate kinase — —

Not shown: 3 genomes with orthologs for ECD_00373 only; 16 genomes with orthologs for ECD_01825 only