Conservation of cofitness between CSW01_02450 and CSW01_13810 in Vibrio cholerae E7946 ATCC 55056

78 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Vibrio cholerae E7946 ATCC 55056 1.0 CSW01_02450 pyrroline-5-carboxylate reductase 1.0 CSW01_13810 phosphoenolpyruvate carboxykinase (ATP) 0.86 6
Pectobacterium carotovorum WPP14 0.69 HER17_RS03805 pyrroline-5-carboxylate reductase 0.80 HER17_RS01710 phosphoenolpyruvate carboxykinase (ATP) — —
Serratia liquefaciens MT49 0.69 IAI46_21415 pyrroline-5-carboxylate reductase 0.81 IAI46_23770 phosphoenolpyruvate carboxykinase (ATP) low > 87
Dickeya dadantii 3937 0.68 DDA3937_RS17305 pyrroline-5-carboxylate reductase 0.81 DDA3937_RS19610 phosphoenolpyruvate carboxykinase (ATP) low > 74
Dickeya dianthicola 67-19 0.68 HGI48_RS17350 pyrroline-5-carboxylate reductase 0.81 HGI48_RS19740 phosphoenolpyruvate carboxykinase (ATP) — —
Dickeya dianthicola ME23 0.67 DZA65_RS18440 pyrroline-5-carboxylate reductase 0.81 DZA65_RS20830 phosphoenolpyruvate carboxykinase (ATP) — —
Rahnella sp. WP5 0.65 EX31_RS02690 pyrroline-5-carboxylate reductase 0.79 EX31_RS04780 phosphoenolpyruvate carboxykinase (ATP) low > 89
Alteromonas macleodii MIT1002 0.60 MIT1002_03062 Pyrroline-5-carboxylate reductase 0.36 MIT1002_03972 Phosphoenolpyruvate carboxykinase [ATP] low > 70
Shewanella oneidensis MR-1 0.57 SO3354 proC pyrroline-5-carboxylate reductase (NCBI ptt file) 0.36 SO0162 pckA phosphoenolpyruvate carboxykinase (ATP) (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.56 Shewana3_1193 pyrroline-5-carboxylate reductase (RefSeq) 0.36 Shewana3_0147 phosphoenolpyruvate carboxykinase (RefSeq) low > 73
Shewanella loihica PV-4 0.52 Shew_1136 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.37 Shew_3623 phosphoenolpyruvate carboxykinase (RefSeq) low > 60
Shewanella amazonensis SB2B 0.50 Sama_2478 pyrroline-5-carboxylate reductase (RefSeq) 0.38 Sama_0165 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) (from data) low > 62
Kangiella aquimarina DSM 16071 0.42 B158DRAFT_0197 pyrroline-5-carboxylate reductase 0.76 B158DRAFT_2395 phosphoenolpyruvate carboxykinase (ATP) low > 40
Marinobacter adhaerens HP15 0.38 HP15_287 pyrroline-5-carboxylate reductase 0.36 HP15_3498 phosphoenolpyruvate carboxykinase (ATP) — —
Pseudomonas sp. BP01 0.37 JOY50_RS20905 proC pyrroline-5-carboxylate reductase 0.33 JOY50_RS18315 phosphoenolpyruvate carboxykinase 0.70 34
Pseudomonas lactucae CFBP13502 0.37 GEMAOFIL_05483 Pyrroline-5-carboxylate reductase 0.35 GEMAOFIL_00469 Phosphoenolpyruvate carboxykinase (ATP) — —
Pseudomonas orientalis W4I3 0.37 QF045_RS01130 pyrroline-5-carboxylate reductase 0.35 QF045_RS04340 phosphoenolpyruvate carboxykinase low > 93
Pseudomonas fluorescens SBW25 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.34 PFLU_RS01320 phosphoenolpyruvate carboxykinase — —
Pseudomonas fluorescens SBW25-INTG 0.37 PFLU_RS28375 pyrroline-5-carboxylate reductase 0.34 PFLU_RS01320 phosphoenolpyruvate carboxykinase — —
Pseudomonas sp. SVBP6 0.36 COO64_RS12995 proC pyrroline-5-carboxylate reductase 0.33 COO64_RS00660 phosphoenolpyruvate carboxykinase — —
Pseudomonas simiae WCS417 0.36 PS417_26730 pyrroline-5-carboxylate reductase 0.34 PS417_01210 hypothetical protein low > 88
Pseudomonas syringae pv. syringae B728a 0.36 Psyr_0476 pyrroline-5-carboxylate reductase 0.33 Psyr_0168 Phosphoenolpyruvate carboxykinase (ATP) — —
Pseudomonas segetis P6 0.36 ACVTMO_RS03015 proC pyrroline-5-carboxylate reductase 0.32 ACVTMO_RS03850 phosphoenolpyruvate carboxykinase — —
Pseudomonas syringae pv. syringae B728a ΔmexB 0.36 Psyr_0476 pyrroline-5-carboxylate reductase 0.33 Psyr_0168 Phosphoenolpyruvate carboxykinase (ATP) low > 86
Pseudomonas fluorescens FW300-N2C3 0.36 AO356_13420 pyrroline-5-carboxylate reductase 0.32 AO356_10140 phosphoenolpyruvate carboxykinase [ATP] — —
Pseudomonas fluorescens FW300-N2E3 0.36 AO353_08165 pyrroline-5-carboxylate reductase 0.33 AO353_11775 phosphoenolpyruvate carboxykinase [ATP] low > 101
Pseudomonas fluorescens GW456-L13 0.35 PfGW456L13_1010 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.33 PfGW456L13_420 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) low > 87
Pseudomonas aeruginosa PUPa3 0.35 DQ20_RS37355 proC;go_function=pyrroline-5-carboxylate pyrroline-5-carboxylate reductase 0.34 DQ20_RS50285 phosphoenolpyruvate carboxykinase low > 101
Pseudomonas aeruginosa PA14 0.35 IKLFDK_23455 pyrroline-5-carboxylate reductase 0.34 IKLFDK_27515 phosphoenolpyruvate carboxykinase low > 98
Pseudomonas fluorescens FW300-N2E2 0.35 Pf6N2E2_4600 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.32 Pf6N2E2_3899 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) — —
Pseudomonas aeruginosa MRSN321 0.35 DY961_RS21945 proC;go_function=pyrroline-5-carboxylate pyrroline-5-carboxylate reductase 0.34 DY961_RS11825 phosphoenolpyruvate carboxykinase — —
Pseudomonas sp. RS175 0.35 PFR28_04243 Pyrroline-5-carboxylate reductase 0.34 PFR28_04874 Phosphoenolpyruvate carboxykinase (ATP) — —
Pseudomonas sp. S08-1 0.35 OH686_10980 pyrroline-5-carboxylate reductase 0.32 OH686_11060 phosphoenolpyruvate carboxykinase (ATP) low > 80
Pseudomonas fluorescens FW300-N1B4 0.35 Pf1N1B4_2341 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.34 Pf1N1B4_1779 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) — —
Pseudomonas stutzeri RCH2 0.34 Psest_0283 pyrroline-5-carboxylate reductase 0.33 Psest_3988 phosphoenolpyruvate carboxykinase (ATP) — —
Pseudomonas sp. DMC3 0.34 GFF210 Pyrroline-5-carboxylate reductase 0.33 GFF4175 Phosphoenolpyruvate carboxykinase (ATP) — —
Escherichia fergusonii Becca 0.27 EFB2_03670 Pyrroline-5-carboxylate reductase 0.81 EFB2_00425 Phosphoenolpyruvate carboxykinase (ATP) low > 86
Enterobacter asburiae PDN3 0.27 EX28DRAFT_2585 pyrroline-5-carboxylate reductase 0.79 EX28DRAFT_4140 phosphoenolpyruvate carboxykinase (ATP) low > 76
Enterobacter sp. TBS_079 0.27 MPMX20_00976 Pyrroline-5-carboxylate reductase 0.79 MPMX20_04290 Phosphoenolpyruvate carboxykinase (ATP) low > 85
Klebsiella pneumoniae MKP103 0.27 KDGMDA_14250 pyrroline-5-carboxylate reductase 0.81 KDGMDA_06970 phosphoenolpyruvate carboxykinase (ATP) low > 95
Klebsiella michiganensis M5al 0.27 BWI76_RS06170 pyrroline-5-carboxylate reductase 0.79 BWI76_RS26155 phosphoenolpyruvate carboxykinase (ATP) — —
Escherichia coli BW25113 0.27 b0386 proC pyrroline-5-carboxylate reductase (NCBI) 0.81 b3403 pck phosphoenolpyruvate carboxykinase (NCBI) low > 76
Escherichia coli HS(pFamp)R (ATCC 700891) 0.27 OHPLBJKB_03288 Pyrroline-5-carboxylate reductase 0.81 OHPLBJKB_00300 Phosphoenolpyruvate carboxykinase (ATP) low > 74
Escherichia coli ECRC62 0.27 BNILDI_22950 proC pyrroline-5-carboxylate reductase 0.81 BNILDI_02685 pckA phosphoenolpyruvate carboxykinase (ATP) low > 75
Escherichia coli Nissle 1917 0.27 ECOLIN_RS02345 pyrroline-5-carboxylate reductase 0.81 ECOLIN_RS19435 phosphoenolpyruvate carboxykinase (ATP) low > 55
Escherichia coli ECOR27 0.27 NOLOHH_01535 proC pyrroline-5-carboxylate reductase 0.81 NOLOHH_08835 pckA phosphoenolpyruvate carboxykinase (ATP) low > 76
Escherichia coli ECOR38 0.27 HEPCGN_07250 proC pyrroline-5-carboxylate reductase 0.81 HEPCGN_15865 pckA phosphoenolpyruvate carboxykinase (ATP) low > 88
Escherichia coli BL21 0.27 ECD_00333 pyrroline-5-carboxylate reductase, NAD(P)-binding 0.81 ECD_03255 phosphoenolpyruvate carboxykinase [ATP] low > 61
Escherichia coli ECRC101 0.27 MCAODC_27835 proC pyrroline-5-carboxylate reductase 0.81 MCAODC_07575 pckA phosphoenolpyruvate carboxykinase (ATP) low > 87
Escherichia coli ECRC98 0.27 JDDGAC_12265 proC pyrroline-5-carboxylate reductase 0.81 JDDGAC_20675 pckA phosphoenolpyruvate carboxykinase (ATP) low > 87
Escherichia coli ECRC99 0.27 KEDOAH_19355 proC pyrroline-5-carboxylate reductase 0.81 KEDOAH_11095 pckA phosphoenolpyruvate carboxykinase (ATP) — —
Escherichia coli ECRC102 0.27 NIAGMN_06665 proC pyrroline-5-carboxylate reductase 0.81 NIAGMN_14815 pckA phosphoenolpyruvate carboxykinase (ATP) low > 80
Escherichia coli ECRC100 0.27 OKFHMN_08610 proC pyrroline-5-carboxylate reductase 0.81 OKFHMN_17045 pckA phosphoenolpyruvate carboxykinase (ATP) low > 79
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.26 GFF4283 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.81 GFF615 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) low > 78
Erwinia amylovora T8 0.26 OLJFJH_18285 pyrroline-5-carboxylate reductase 0.78 OLJFJH_04150 phosphoenolpyruvate carboxykinase (ATP) — —
Pantoea sp. MT58 0.26 IAI47_14945 pyrroline-5-carboxylate reductase 0.77 IAI47_01830 phosphoenolpyruvate carboxykinase (ATP) low > 76
Pantoea agglomerans CFBP13505 P0401 0.26 PagCFBP13505_RS10205 pyrroline-5-carboxylate reductase 0.77 PagCFBP13505_RS18350 phosphoenolpyruvate carboxykinase (ATP) low > 74
Agrobacterium fabrum C58 0.24 Atu2209 pyrroline-5-carboxylate reductase 0.42 Atu0035 phosphoenolpyruvate carboxykinase low > 89
Sinorhizobium meliloti 1021 0.24 SMc02677 pyrroline-5-carboxylate reductase 0.41 SMc02562 phosphoenolpyruvate carboxykinase low > 103
Rhodopseudomonas palustris CGA009 0.24 TX73_022630 pyrroline-5-carboxylate reductase 0.42 TX73_001865 phosphoenolpyruvate carboxykinase — —
Erwinia tracheiphila HP pepo 2.2 0.23 IJEDHG_26195 proC pyrroline-5-carboxylate reductase 0.78 IJEDHG_11970 pckA phosphoenolpyruvate carboxykinase (ATP) — —
Erwinia tracheiphila SCR3 0.23 LU632_RS18995 proC pyrroline-5-carboxylate reductase 0.78 LU632_RS22930 pckA phosphoenolpyruvate carboxykinase (ATP) low > 73
Echinicola vietnamensis KMM 6221, DSM 17526 0.23 Echvi_2635 pyrroline-5-carboxylate reductase 0.42 Echvi_2957 phosphoenolpyruvate carboxykinase (ATP) — —
Rhizobium sp. OAE497 0.23 ABIE40_RS13005 pyrroline-5-carboxylate reductase 0.40 ABIE40_RS19415 phosphoenolpyruvate carboxykinase low > 107
Xanthobacter sp. DMC5 0.22 GFF1925 Pyrroline-5-carboxylate reductase 0.40 GFF4136 Phosphoenolpyruvate carboxykinase (ATP) — —
Sphingomonas koreensis DSMZ 15582 0.22 Ga0059261_3321 pyrroline-5-carboxylate reductase 0.39 Ga0059261_0913 phosphoenolpyruvate carboxykinase (ATP) low > 68
Bacteroides ovatus ATCC 8483 0.21 BACOVA_03587 pyrroline-5-carboxylate reductase 0.72 BACOVA_02011 phosphoenolpyruvate carboxykinase (ATP) — —
Dinoroseobacter shibae DFL-12 0.20 Dshi_2645 pyrroline-5-carboxylate reductase (RefSeq) 0.39 Dshi_0213 Phosphoenolpyruvate carboxykinase (ATP) (RefSeq) — —
Bosea sp. OAE506 0.19 ABIE41_RS11365 pyrroline-5-carboxylate reductase 0.40 ABIE41_RS02665 phosphoenolpyruvate carboxykinase — —
Phaeobacter inhibens DSM 17395 0.19 PGA1_c24700 pyrroline-5-carboxylate reductase ProC 0.39 PGA1_c01140 phosphoenolpyruvate carboxykinase 0.59 62
Bacteroides thetaiotaomicron VPI-5482 0.19 BT3757 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.73 BT2790 phosphoenolpyruvate carboxykinase [ATP] (NCBI ptt file) — —
Pontibacter actiniarum KMM 6156, DSM 19842 0.16 CA264_07730 pyrroline-5-carboxylate reductase 0.44 CA264_05270 phosphoenolpyruvate carboxykinase (ATP) — —
Pedobacter sp. GW460-11-11-14-LB5 0.15 CA265_RS18505 pyrroline-5-carboxylate reductase (EC 1.5.1.2) (from data) 0.41 CA265_RS23490 phosphoenolpyruvate carboxykinase (ATP) low > 88
Phocaeicola vulgatus CL09T03C04 0.15 HMPREF1058_RS08830 pyrroline-5-carboxylate reductase 0.72 HMPREF1058_RS10065 phosphoenolpyruvate carboxykinase (ATP) — —
Phocaeicola dorei CL03T12C01 0.15 ABI39_RS02960 pyrroline-5-carboxylate reductase 0.72 ABI39_RS06685 phosphoenolpyruvate carboxykinase (ATP) — —
Parabacteroides merdae CL09T00C40 0.15 HMPREF1078_RS10620 pyrroline-5-carboxylate reductase 0.72 HMPREF1078_RS07235 phosphoenolpyruvate carboxykinase (ATP) — —
Bacteroides stercoris CC31F 0.15 HMPREF1181_RS03440 pyrroline-5-carboxylate reductase 0.72 HMPREF1181_RS01170 phosphoenolpyruvate carboxykinase (ATP) — —
Cellulophaga baltica 18 0.14 M666_RS02635 pyrroline-5-carboxylate reductase 0.43 M666_RS03005 phosphoenolpyruvate carboxykinase (ATP) low > 67
Sphingobium sp. HT1-2 0.13 GFF2491 Pyrroline-5-carboxylate reductase (EC 1.5.1.2) 0.40 GFF3825 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) low > 95

Not shown: 42 genomes with orthologs for CSW01_02450 only; 1 genomes with orthologs for CSW01_13810 only