| Organism | Ratio1 | Gene1 | Name1 | Description1 | Ratio2 | Gene2 | Name2 | Description2 | Cofit | Rank |
| Vibrio cholerae E7946 ATCC 55056 | 1.0 | CSW01_19520 | | chemotaxis response regulator protein-glutamate methylesterase | 1.0 | CSW01_02560 | | chromosome initiation inhibitor | 0.44 | 19 |
| Shewanella loihica PV-4 | 0.48 | Shew_0109 | | response regulator receiver modulated CheB methylesterase (RefSeq) | 0.42 | Shew_1844 | | chromosome replication initiation inhibitor protein (RefSeq) | low | > 60 |
| Xanthomonas campestris pv. campestris strain 8004 | 0.46 | Xcc-8004.2888.1 | | Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) | 0.26 | Xcc-8004.1463.1 | | Transcriptional regulator lysR family | low | > 74 |
| Dyella japonica UNC79MFTsu3.2 | 0.46 | ABZR86_RS22205 | | chemotaxis response regulator protein-glutamate methylesterase | 0.27 | ABZR86_RS10990 | | LysR family transcriptional regulator ArgP | low | > 74 |
| Serratia liquefaciens MT49 | 0.45 | IAI46_16015 | | chemotaxis response regulator protein-glutamate methylesterase | 0.45 | IAI46_20910 | | LysR family transcriptional regulator ArgP | low | > 87 |
| Erwinia tracheiphila SCR3 | 0.45 | LU632_RS13525 | | chemotaxis response regulator protein-glutamate methylesterase | 0.45 | LU632_RS05845 | | LysR family transcriptional regulator ArgP | low | > 73 |
| Erwinia tracheiphila HP pepo 2.2 | 0.45 | IJEDHG_22020 | cheB | chemotaxis response regulator protein-glutamate methylesterase | 0.45 | IJEDHG_03330 | argP | HTH-type transcriptional regulator ArgP | low | > 61 |
| Rahnella sp. WP5 | 0.45 | EX31_RS11360 | | chemotaxis response regulator protein-glutamate methylesterase | 0.46 | EX31_RS21460 | | LysR family transcriptional regulator ArgP | low | > 89 |
| Dickeya dadantii 3937 | 0.45 | DDA3937_RS13525 | | chemotaxis response regulator protein-glutamate methylesterase | 0.45 | DDA3937_RS18490 | | LysR family transcriptional regulator ArgP | low | > 74 |
| Dickeya dianthicola ME23 | 0.45 | DZA65_RS14055 | | chemotaxis response regulator protein-glutamate methylesterase | 0.46 | DZA65_RS19550 | | LysR family transcriptional regulator ArgP | low | > 75 |
| Dickeya dianthicola 67-19 | 0.45 | HGI48_RS13570 | | chemotaxis response regulator protein-glutamate methylesterase | 0.46 | HGI48_RS18415 | | LysR family transcriptional regulator ArgP | low | > 71 |
| Shewanella amazonensis SB2B | 0.45 | Sama_3499 | | protein-glutamate methylesterase (RefSeq) | 0.40 | Sama_2987 | | chromosome replication initiation inhibitor protein (RefSeq) | low | > 62 |
| Enterobacter sp. TBS_079 | 0.45 | MPMX20_02787 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | 0.45 | MPMX20_03773 | | HTH-type transcriptional regulator ArgP | low | > 85 |
| Erwinia amylovora T8 | 0.44 | OLJFJH_12760 | | chemotaxis response regulator protein-glutamate methylesterase | 0.44 | OLJFJH_08715 | | HTH-type transcriptional regulator ArgP | low | > 58 |
| Pectobacterium carotovorum WPP14 | 0.44 | HER17_RS08120 | | chemotaxis response regulator protein-glutamate methylesterase | 0.44 | HER17_RS02715 | | LysR family transcriptional regulator ArgP | low | > 75 |
| Enterobacter asburiae PDN3 | 0.44 | EX28DRAFT_0673 | | Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain | 0.45 | EX28DRAFT_2967 | | transcriptional regulator, ArgP family | low | > 76 |
| Escherichia coli ECRC100 | 0.44 | OKFHMN_26150 | cheB | protein-glutamate methylesterase/protein glutamine deamidase | 0.44 | OKFHMN_19450 | argP | DNA-binding transcriptional regulator ArgP | low | > 79 |
| Escherichia coli BL21 | 0.44 | ECD_01854 | | fused chemotaxis regulator: protein-glutamate methylesterase in two-component regulatory system with CheA | 0.44 | ECD_02747 | | transcriptional regulator for arginine transport and DNA replication genes; replication initiation inhibitor | low | > 61 |
| Escherichia coli ECRC99 | 0.44 | KEDOAH_01955 | cheB | protein-glutamate methylesterase/protein glutamine deamidase | 0.44 | KEDOAH_08690 | argP | DNA-binding transcriptional regulator ArgP | — | — |
| Escherichia coli ECRC102 | 0.44 | NIAGMN_01910 | cheB | protein-glutamate methylesterase/protein glutamine deamidase | 0.44 | NIAGMN_17215 | argP | DNA-binding transcriptional regulator ArgP | low | > 80 |
| Escherichia coli HS(pFamp)R (ATCC 700891) | 0.44 | OHPLBJKB_01845 | | Chemotaxis response regulator protein-glutamate methylesterase | 0.44 | OHPLBJKB_00800 | | HTH-type transcriptional regulator ArgP | low | > 74 |
| Escherichia coli ECRC98 | 0.44 | JDDGAC_00725 | cheB | protein-glutamate methylesterase/protein glutamine deamidase | 0.44 | JDDGAC_23090 | argP | DNA-binding transcriptional regulator ArgP | 0.54 | 18 |
| Escherichia coli ECRC101 | 0.44 | MCAODC_19255 | cheB | protein-glutamate methylesterase/protein glutamine deamidase | 0.44 | MCAODC_09970 | argP | DNA-binding transcriptional regulator ArgP | low | > 87 |
| Escherichia coli Nissle 1917 | 0.44 | ECOLIN_RS10755 | | protein-glutamate methylesterase/protein glutamine deamidase | 0.44 | ECOLIN_RS16225 | | DNA-binding transcriptional regulator ArgP | — | — |
| Escherichia coli ECOR38 | 0.44 | HEPCGN_04570 | cheB | protein-glutamate methylesterase/protein glutamine deamidase | 0.44 | HEPCGN_18750 | argP | DNA-binding transcriptional regulator ArgP | low | > 88 |
| Escherichia coli BW25113 | 0.44 | b1883 | cheB | chemotaxis-specific methylesterase (NCBI) | 0.44 | b2916 | argP | chromosome replication initiation inhibitor protein (NCBI) | low | > 76 |
| Escherichia coli ECRC62 | 0.44 | BNILDI_15380 | cheB | protein-glutamate methylesterase/protein glutamine deamidase | 0.44 | BNILDI_09890 | argP | DNA-binding transcriptional regulator ArgP | low | > 75 |
| Escherichia coli ECOR27 | 0.44 | NOLOHH_16590 | cheB | protein-glutamate methylesterase/protein glutamine deamidase | 0.44 | NOLOHH_11355 | argP | DNA-binding transcriptional regulator ArgP | low | > 76 |
| Escherichia fergusonii Becca | 0.44 | EFB2_02060 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | 0.44 | EFB2_00987 | | HTH-type transcriptional regulator ArgP | 0.51 | 5 |
| Variovorax sp. SCN45 | 0.44 | GFF5767 | | Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) | 0.23 | GFF2318 | | Transcriptional regulator ArgP, LysR family | low | > 127 |
| Pantoea agglomerans CFBP13505 P0401 | 0.43 | PagCFBP13505_RS02210 | | chemotaxis response regulator protein-glutamate methylesterase | 0.45 | PagCFBP13505_RS15985 | | LysR family transcriptional regulator ArgP | low | > 74 |
| Cupriavidus basilensis FW507-4G11 | 0.43 | RR42_RS35785 | | chemotaxis protein | 0.28 | RR42_RS31465 | | LysR family transcriptional regulator | low | > 128 |
| Paraburkholderia bryophila 376MFSha3.1 | 0.43 | H281DRAFT_05747 | | two-component system, chemotaxis family, response regulator CheB | 0.29 | H281DRAFT_04882 | | transcriptional regulator, LysR family | — | — |
| Burkholderia phytofirmans PsJN | 0.43 | BPHYT_RS18970 | | chemotaxis protein | 0.28 | BPHYT_RS07440 | | LysR family transcriptional regulator | — | — |
| Paraburkholderia sabiae LMG 24235 | 0.43 | QEN71_RS28985 | | chemotaxis response regulator protein-glutamate methylesterase | 0.29 | QEN71_RS23610 | | LysR family transcriptional regulator ArgP | low | > 153 |
| Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | 0.43 | GFF1664 | | Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) | 0.46 | GFF3015 | | Chromosome initiation inhibitor | low | > 78 |
| Pantoea sp. MT58 | 0.43 | IAI47_08330 | | chemotaxis response regulator protein-glutamate methylesterase | 0.45 | IAI47_03715 | | LysR family transcriptional regulator ArgP | low | > 76 |
| Paraburkholderia graminis OAS925 | 0.43 | ABIE53_000119 | | two-component system chemotaxis response regulator CheB | 0.29 | ABIE53_001719 | | LysR family transcriptional regulator (chromosome initiation inhibitor) | low | > 113 |
| Azospirillum brasilense Sp245 | 0.42 | AZOBR_RS14260 | | chemotaxis protein | 0.26 | AZOBR_RS01600 | | LysR family transcriptional regulator | low | > 97 |
| Hydrogenophaga sp. GW460-11-11-14-LB1 | 0.42 | GFF1479 | | Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) | 0.29 | GFF5065 | | Chromosome initiation inhibitor | — | — |
| Shewanella oneidensis MR-1 | 0.41 | SO2126 | cheB-1 | protein-glutamate methylesterase CheB (NCBI ptt file) | 0.37 | SO2866 | iciA | chromosome initiation inhibitor (NCBI ptt file) | low | > 76 |
| Rhodanobacter sp. FW510-T8 | 0.41 | OKGIIK_02915 | cheB | Chemotaxis response regulator CheB, contains REC and protein-glutamate methylesterase domains | 0.27 | OKGIIK_01770 | | Transcriptional regulator ArgP | low | > 53 |
| Shewanella sp. ANA-3 | 0.41 | Shewana3_2213 | | response regulator receiver modulated CheB methylesterase (RefSeq) | 0.37 | Shewana3_1652 | | chromosome replication initiation inhibitor protein (RefSeq) | low | > 73 |
| Acidovorax sp. GW101-3H11 | 0.40 | Ac3H11_1425 | | Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) | 0.27 | Ac3H11_3378 | | chromosome replication initiation inhibitor protein | low | > 79 |
| Ralstonia sp. UNC404CL21Col | 0.40 | ABZR87_RS17990 | | chemotaxis response regulator protein-glutamate methylesterase | 0.30 | ABZR87_RS14025 | | LysR family transcriptional regulator ArgP | low | > 80 |
| Agrobacterium fabrum C58 | 0.40 | Atu0519 | | protein-glutamate methylesterase | 0.27 | Atu0928 | | transcriptional regulator, LysR family | low | > 89 |
| Ralstonia solanacearum PSI07 | 0.40 | RPSI07_RS06230 | | chemotaxis response regulator protein-glutamate methylesterase | 0.30 | RPSI07_RS03900 | | transcriptional regulator ArgP | low | > 81 |
| Azospirillum sp. SherDot2 | 0.40 | MPMX19_01953 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | 0.28 | MPMX19_01759 | | putative HTH-type transcriptional regulator | low | > 112 |
| Ralstonia solanacearum IBSBF1503 | 0.40 | RALBFv3_RS17415 | | chemotaxis response regulator protein-glutamate methylesterase | 0.31 | RALBFv3_RS18360 | | transcriptional regulator ArgP | low | > 76 |
| Ralstonia solanacearum UW163 | 0.40 | UW163_RS21735 | | chemotaxis response regulator protein-glutamate methylesterase | 0.31 | UW163_RS20770 | | transcriptional regulator ArgP | — | — |
| Rhodospirillum rubrum S1H | 0.40 | Rru_A1406 | | Two component CheB methylesterase (NCBI) | 0.27 | Rru_A0658 | | Transcriptional Regulator, LysR family (NCBI) | low | > 58 |
| Pseudomonas aeruginosa PA14 | 0.40 | IKLFDK_24680 | | Protein-glutamate methylesterase/protein-glutamine glutaminase 2 | 0.34 | IKLFDK_02285 | | HTH-type transcriptional regulator ArgP | low | > 98 |
| Pseudomonas aeruginosa MRSN321 | 0.39 | DY961_RS27150 | | chemotaxis response regulator protein-glutamate methylesterase | 0.35 | DY961_RS24675 | | LysR family transcriptional regulator ArgP | low | > 100 |
| Pseudomonas aeruginosa PUPa3 | 0.39 | DQ20_RS31680 | | chemotaxis response regulator protein-glutamate methylesterase | 0.34 | DQ20_RS57125 | | LysR family transcriptional regulator ArgP | low | > 101 |
| Pseudomonas fluorescens SBW25-INTG | 0.38 | PFLU_RS24965 | | chemotaxis response regulator protein-glutamate methylesterase | 0.32 | PFLU_RS23790 | | LysR family transcriptional regulator ArgP | low | > 109 |
| Pseudomonas fluorescens SBW25 | 0.38 | PFLU_RS24965 | | chemotaxis response regulator protein-glutamate methylesterase | 0.32 | PFLU_RS23790 | | LysR family transcriptional regulator ArgP | low | > 109 |
| Pseudomonas fluorescens FW300-N2E2 | 0.38 | Pf6N2E2_1775 | | Chemotaxis response regulator protein-glutamate methylesterase CheB (EC 3.1.1.61) | 0.31 | Pf6N2E2_2849 | | Chromosome initiation inhibitor | low | > 103 |
| Desulfovibrio vulgaris Hildenborough JW710 | 0.37 | DVU1596 | cheB-1 | protein-glutamate methylesterase CheB (TIGR) | 0.34 | DVU0594 | iciA | chromosome initiation inhibitor (TIGR) | low | > 55 |
| Pseudomonas syringae pv. syringae B728a ΔmexB | 0.37 | Psyr_0781 | | Protein-glutamate methylesterase | 0.34 | Psyr_4057 | | regulatory protein, LysR:LysR, substrate-binding protein | low | > 86 |
| Pseudomonas syringae pv. syringae B728a | 0.37 | Psyr_0781 | | Protein-glutamate methylesterase | 0.34 | Psyr_4057 | | regulatory protein, LysR:LysR, substrate-binding protein | low | > 86 |
| Pseudomonas fluorescens FW300-N2C3 | 0.37 | AO356_29840 | | chemotaxis protein CheY | 0.32 | AO356_04995 | | LysR family transcriptional regulator | 0.20 | 76 |
| Pseudomonas sp. RS175 | 0.37 | PFR28_01434 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | 0.31 | PFR28_00608 | | HTH-type transcriptional regulator ArgP | low | > 88 |
| Pseudomonas stutzeri RCH2 | 0.37 | Psest_0653 | | Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain | 0.32 | Psest_1166 | | transcriptional regulator, ArgP family | — | — |
| Pseudomonas lactucae CFBP13502 | 0.36 | GEMAOFIL_03221 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | 0.31 | GEMAOFIL_04569 | | HTH-type transcriptional regulator ArgP | — | — |
| Desulfovibrio vulgaris Miyazaki F | 0.36 | DvMF_0465 | | response regulator receiver modulated CheB methylesterase (RefSeq) | 0.29 | DvMF_2123 | | chromosome replication initiation inhibitor protein (RefSeq) | low | > 51 |
| Pseudomonas sp. S08-1 | 0.35 | OH686_21840 | | Chemotaxis response regulator protein-glutamate methylesterase CheB | 0.30 | OH686_07195 | | Transcriptional regulator ArgP, LysR family | low | > 80 |
| Phaeobacter inhibens DSM 17395 | 0.18 | PGA1_262p02160 | | putative chemotaxis response regulator protein-glutamate methylesterase | 0.23 | PGA1_c21740 | | transcriptional regulator, ArgP family | low | > 62 |
Not shown: 20 genomes with orthologs for CSW01_19520 only; 18 genomes with orthologs for CSW01_02560 only