Conservation of cofitness between BPHYT_RS14785 and BPHYT_RS33835 in Burkholderia phytofirmans PsJN

68 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Burkholderia phytofirmans PsJN 1.0 BPHYT_RS14785 AsnC family transcriptional regulator 1.0 BPHYT_RS33835 O-succinylhomoserine sulfhydrylase 0.24 18
Paraburkholderia bryophila 376MFSha3.1 0.99 H281DRAFT_04288 transcriptional regulator, AsnC family 0.94 H281DRAFT_06059 O-succinylhomoserine sulfhydrylase low > 103
Paraburkholderia graminis OAS925 0.98 ABIE53_003132 Lrp/AsnC family leucine-responsive transcriptional regulator 0.93 ABIE53_004817 O-succinylhomoserine sulfhydrylase low > 113
Paraburkholderia sabiae LMG 24235 0.94 QEN71_RS04195 Lrp/AsnC ligand binding domain-containing protein 0.88 QEN71_RS17685 O-succinylhomoserine sulfhydrylase low > 153
Cupriavidus basilensis FW507-4G11 0.83 RR42_RS04590 AsnC family transcriptional regulator 0.73 RR42_RS14320 O-succinylhomoserine sulfhydrylase 0.34 25
Pseudomonas sp. S08-1 0.72 OH686_13680 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.56 OH686_04415 O-succinylhomoserine sulfhydrylase low > 80
Pseudomonas syringae pv. syringae B728a ΔmexB 0.72 Psyr_0234 transcriptional regulator, AsnC family 0.57 Psyr_1669 O-succinylhomoserine sulfhydrylase low > 86
Pseudomonas syringae pv. syringae B728a 0.72 Psyr_0234 transcriptional regulator, AsnC family 0.57 Psyr_1669 O-succinylhomoserine sulfhydrylase low > 86
Pseudomonas putida KT2440 0.71 PP_5271 DNA-binding transcriptional dual regulator, leucine-binding 0.53 PP_2001 O-succinylhomoserine sulfhydrylase low > 96
Pseudomonas fluorescens GW456-L13 0.71 PfGW456L13_811 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.55 PfGW456L13_3934 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 87
Pseudomonas sp. RS175 0.70 PFR28_04400 Leucine-responsive regulatory protein 0.55 PFR28_02810 O-succinylhomoserine sulfhydrylase low > 88
Pseudomonas fluorescens SBW25 0.70 PFLU_RS29385 AsnC family transcriptional regulator 0.55 PFLU_RS20510 O-succinylhomoserine sulfhydrylase low > 109
Pseudomonas fluorescens FW300-N1B4 0.70 Pf1N1B4_2143 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.33 Pf1N1B4_4890 Cystathionine gamma-lyase (EC 4.4.1.1) low > 87
Pseudomonas fluorescens FW300-N2E3 0.70 AO353_09160 AsnC family transcriptional regulator 0.55 AO353_20695 O-succinylhomoserine sulfhydrylase low > 101
Pseudomonas simiae WCS417 0.70 PS417_27710 AsnC family transcriptional regulator 0.55 PS417_18530 O-succinylhomoserine sulfhydrylase low > 88
Pseudomonas fluorescens SBW25-INTG 0.70 PFLU_RS29385 AsnC family transcriptional regulator 0.55 PFLU_RS20510 O-succinylhomoserine sulfhydrylase low > 109
Castellaniella sp019104865 MT123 0.70 ABCV34_RS10805 winged helix-turn-helix transcriptional regulator 0.34 ABCV34_RS15785 aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme low > 48
Pseudomonas fluorescens FW300-N2E2 0.70 Pf6N2E2_4390 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.55 Pf6N2E2_77 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 103
Pseudomonas fluorescens FW300-N2C3 0.70 AO356_12615 AsnC family transcriptional regulator 0.55 AO356_21470 O-succinylhomoserine sulfhydrylase low > 104
Pseudomonas stutzeri RCH2 0.69 Psest_3794 Transcriptional regulators 0.54 Psest_2578 O-succinylhomoserine sulfhydrylase 0.16 57
Xanthomonas campestris pv. campestris strain 8004 0.68 Xcc-8004.4622.1 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.33 Xcc-8004.4517.1 Cystathionine gamma-lyase (EC 4.4.1.1) low > 74
Rhodanobacter denitrificans FW104-10B01 0.66 LRK54_RS00595 winged helix-turn-helix transcriptional regulator 0.32 LRK54_RS05660 PLP-dependent aspartate aminotransferase family protein low > 59
Rhodanobacter denitrificans MT42 0.66 LRK55_RS00365 winged helix-turn-helix transcriptional regulator 0.32 LRK55_RS05410 cystathionine gamma-synthase low > 63
Rhodanobacter sp. FW510-T8 0.66 OKGIIK_06660 lrp AsnC family transcriptional regulator 0.33 OKGIIK_01180 metC cystathionine beta-lyase low > 52
Variovorax sp. OAS795 0.64 ABID97_RS22380 winged helix-turn-helix transcriptional regulator 0.58 ABID97_RS21630 O-succinylhomoserine sulfhydrylase
Variovorax sp. SCN45 0.63 GFF1774 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.56 GFF3088 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) @ O-succinylhomoserine sulfhydrylase (EC 2.5.1.48)
Kangiella aquimarina DSM 16071 0.60 B158DRAFT_1822 Transcriptional regulators 0.40 B158DRAFT_1522 methionine gamma-lyase low > 40
Shewanella amazonensis SB2B 0.58 Sama_1771 leucine-responsive transcriptional regulator (RefSeq) 0.37 Sama_1242 methionine gamma-lyase (RefSeq) low > 62
Shewanella loihica PV-4 0.57 Shew_2025 leucine-responsive transcriptional regulator (RefSeq) 0.35 Shew_2491 methionine gamma-lyase (RefSeq) low > 60
Vibrio cholerae E7946 ATCC 55056 0.57 CSW01_09530 leucine-responsive transcriptional regulator Lrp 0.27 CSW01_13550 O-succinylhomoserine (thiol)-lyase
Shewanella oneidensis MR-1 0.56 SO2305 lrp leucine-responsive regulatory protein (NCBI ptt file) 0.40 SO1812 mdeA Methionine gamma-lyase (EC 4.4.1.11) (from data) low > 76
Shewanella sp. ANA-3 0.56 Shewana3_2049 leucine-responsive transcriptional regulator (RefSeq) 0.40 Shewana3_2643 methionine gamma-lyase (RefSeq) low > 73
Pectobacterium carotovorum WPP14 0.56 HER17_RS12360 leucine-responsive transcriptional regulator Lrp 0.34 HER17_RS07405 PLP-dependent aspartate aminotransferase family protein low > 75
Dickeya dianthicola 67-19 0.56 HGI48_RS09605 leucine-responsive transcriptional regulator Lrp 0.31 HGI48_RS20425 cystathionine gamma-synthase 0.73 25
Dickeya dianthicola ME23 0.56 DZA65_RS09915 leucine-responsive transcriptional regulator Lrp 0.31 DZA65_RS21470 cystathionine gamma-synthase 0.72 15
Dickeya dadantii 3937 0.56 DDA3937_RS09590 leucine-responsive transcriptional regulator Lrp 0.31 DDA3937_RS00950 cystathionine gamma-synthase 0.77 22
Klebsiella michiganensis M5al 0.56 BWI76_RS09655 leucine-responsive regulatory protein 0.32 BWI76_RS24210 cystathionine gamma-lyase low > 92
Escherichia fergusonii Becca 0.55 EFB2_03172 Leucine-responsive regulatory protein 0.31 EFB2_04679 Cystathionine gamma-synthase low > 86
Escherichia coli BW25113 0.55 b0889 lrp DNA-binding transcriptional dual regulator, leucine-binding (NCBI) 0.31 b3939 metB cystathionine gamma-synthase (NCBI) low > 76
Escherichia coli ECRC99 0.55 KEDOAH_22160 lrp leucine-responsive transcriptional regulator Lrp 0.31 KEDOAH_14485 metB cystathionine gamma-synthase
Escherichia coli ECRC100 0.55 OKFHMN_05575 lrp leucine-responsive transcriptional regulator Lrp 0.31 OKFHMN_13675 metB cystathionine gamma-synthase 0.95 22
Escherichia coli ECRC62 0.55 BNILDI_20400 lrp leucine-responsive transcriptional regulator Lrp 0.31 BNILDI_05715 metB cystathionine gamma-synthase 0.94 3
Escherichia coli HS(pFamp)R (ATCC 700891) 0.55 OHPLBJKB_02779 Leucine-responsive regulatory protein 0.31 OHPLBJKB_04111 Cystathionine gamma-synthase low > 73
Escherichia coli ECRC98 0.55 JDDGAC_09385 lrp leucine-responsive transcriptional regulator Lrp 0.31 JDDGAC_17300 metB cystathionine gamma-synthase low > 86
Pantoea sp. MT58 0.55 IAI47_12915 leucine-responsive transcriptional regulator Lrp 0.28 IAI47_00880 cystathionine gamma-synthase 0.90 13
Escherichia coli ECOR38 0.55 HEPCGN_22935 lrp leucine-responsive transcriptional regulator Lrp 0.31 HEPCGN_12345 metB cystathionine gamma-synthase 0.75 60
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.55 GFF4893 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.31 GFF2323 Cystathionine gamma-synthase (EC 2.5.1.48) low > 78
Enterobacter sp. TBS_079 0.55 MPMX20_01551 Leucine-responsive regulatory protein 0.31 MPMX20_01953 Cystathionine beta-lyase low > 85
Escherichia coli ECRC101 0.55 MCAODC_24965 lrp leucine-responsive transcriptional regulator Lrp 0.31 MCAODC_04175 metB cystathionine gamma-synthase low > 87
Escherichia coli BL21 0.55 ECD_00893 leucine-responsive global transcriptional regulator 0.31 ECD_03825 cystathionine gamma-synthase, PLP-dependent 0.57 20
Erwinia tracheiphila SCR3 0.55 LU632_RS09740 lrp leucine-responsive transcriptional regulator Lrp 0.30 LU632_RS19640 metB cystathionine gamma-synthase 0.75 40
Escherichia coli ECOR27 0.55 NOLOHH_22145 lrp leucine-responsive transcriptional regulator Lrp 0.31 NOLOHH_05820 metB cystathionine gamma-synthase 0.83 46
Escherichia coli ECRC102 0.55 NIAGMN_03295 lrp leucine-responsive transcriptional regulator Lrp 0.31 NIAGMN_11430 metB cystathionine gamma-synthase
Escherichia coli Nissle 1917 0.55 ECOLIN_RS04730 leucine-responsive transcriptional regulator Lrp 0.31 ECOLIN_RS22725 cystathionine gamma-synthase 0.42 22
Enterobacter asburiae PDN3 0.55 EX28DRAFT_2043 transcriptional regulator, AsnC family 0.31 EX28DRAFT_1678 Cystathionine beta-lyases/cystathionine gamma-synthases low > 76
Azospirillum brasilense Sp245 0.52 AZOBR_RS23685 AsnC family transcriptional regulator 0.46 AZOBR_RS02140 O-succinylhomoserine sulfhydrylase low > 97
Brevundimonas sp. GW460-12-10-14-LB2 0.51 A4249_RS13055 Lrp/AsnC ligand binding domain-containing protein 0.34 A4249_RS08315 cystathionine gamma-synthase 0.54 7
Bosea sp. OAE506 0.50 ABIE41_RS07920 Lrp/AsnC ligand binding domain-containing protein 0.48 ABIE41_RS03970 O-succinylhomoserine sulfhydrylase low > 77
Hydrogenophaga sp. GW460-11-11-14-LB1 0.49 GFF2725 Leucine-responsive regulatory protein, regulator for leucine (or lrp) regulon and high-affinity branched-chain amino acid transport system 0.60 GFF301 O-acetylhomoserine sulfhydrylase (EC 2.5.1.49) / O-succinylhomoserine sulfhydrylase (EC 2.5.1.48) low > 90
Caulobacter crescentus NA1000 0.49 CCNA_00847 leucine-responsive regulatory protein 0.44 CCNA_02321 O-succinylhomoserine sulfhydrylase low > 66
Caulobacter crescentus NA1000 Δfur 0.49 CCNA_00847 leucine-responsive regulatory protein 0.44 CCNA_02321 O-succinylhomoserine sulfhydrylase low > 67
Sinorhizobium meliloti 1021 0.48 SMc00681 leucine-responsive regulatory protein 0.45 SMc02217 O-succinylhomoserine sulfhydrylase low > 103
Rhodospirillum rubrum S1H 0.47 Rru_A0655 Transcriptional Regulator, AsnC family (NCBI) 0.48 Rru_A3214 O-succinylhomoserine sulfhydrylase (NCBI) low > 58
Azospirillum sp. SherDot2 0.45 MPMX19_03947 Leucine-responsive regulatory protein 0.46 MPMX19_01364 O-succinylhomoserine sulfhydrylase low > 112
Acinetobacter radioresistens SK82 0.45 MPMX26_01467 Leucine-responsive regulatory protein 0.58 MPMX26_01645 O-succinylhomoserine sulfhydrylase low > 36
Marinobacter adhaerens HP15 0.42 HP15_2690 transcriptional regulator, AsnC family 0.55 HP15_1820 methionine gamma-lyase low > 73
Agrobacterium fabrum C58 0.41 Atu4159 AsnC family transcriptional regulator 0.45 Atu0432 O-succinylhomoserine sulfhydrylase low > 89
Rhizobium sp. OAE497 0.38 ABIE40_RS23450 Lrp/AsnC family transcriptional regulator 0.45 ABIE40_RS02340 O-succinylhomoserine sulfhydrylase low > 107
Mycobacterium tuberculosis H37Rv 0.25 Rv3291c Probable transcriptional regulatory protein LrpA (Lrp/AsnC-family) 0.47 Rv0391 Probable O-succinylhomoserine sulfhydrylase MetZ (OSH sulfhydrylase) low > 58

Not shown: 11 genomes with orthologs for BPHYT_RS14785 only; 13 genomes with orthologs for BPHYT_RS33835 only