Conservation of cofitness between BNILDI_14455 and BNILDI_08735 in Escherichia coli ECRC62

64 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC62 1.0 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB 1.0 BNILDI_08735 nadC carboxylating nicotinate-nucleotide diphosphorylase 0.66 16
Escherichia coli ECRC101 1.00 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 MCAODC_01045 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 87
Escherichia coli ECRC99 1.00 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 KEDOAH_17625 nadC carboxylating nicotinate-nucleotide diphosphorylase — —
Escherichia coli Nissle 1917 1.00 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB 1.00 ECOLIN_RS00585 carboxylating nicotinate-nucleotide diphosphorylase low > 55
Escherichia coli ECRC100 1.00 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 OKFHMN_10530 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 80
Escherichia coli ECRC102 1.00 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 NIAGMN_08380 nadC carboxylating nicotinate-nucleotide diphosphorylase — —
Escherichia coli ECRC98 1.00 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 JDDGAC_14125 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 86
Escherichia coli ECOR27 1.00 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 NOLOHH_02875 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 75
Escherichia coli BW25113 1.00 b2075 mdtB multidrug efflux system, subunit B (NCBI) 1.00 b0109 nadC nicotinate-nucleotide pyrophosphorylase (NCBI) low > 76
Escherichia fergusonii Becca 1.00 EFB2_01780 Multidrug resistance protein MdtB 1.00 EFB2_03940 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01629 Multidrug resistance protein MdtB 0.99 OHPLBJKB_03552 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 73
Escherichia coli BL21 0.99 ECD_01980 multidrug efflux system, subunit B 1.00 ECD_00108 quinolinate phosphoribosyltransferase low > 61
Escherichia coli ECOR38 0.99 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB 1.00 HEPCGN_08510 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 87
Klebsiella michiganensis M5al 0.90 BWI76_RS19255 multidrug transporter subunit MdtB 0.82 BWI76_RS04845 nicotinate-nucleotide pyrophosphorylase low > 92
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.90 GFF3854 Multidrug transporter MdtB 0.87 GFF130 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 78
Enterobacter sp. TBS_079 0.89 MPMX20_03061 Multidrug resistance protein MdtB 0.82 MPMX20_00800 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 85
Enterobacter asburiae PDN3 0.89 EX28DRAFT_0483 Cation/multidrug efflux pump 0.81 EX28DRAFT_3702 nicotinate-nucleotide pyrophosphorylase [carboxylating] (EC 2.4.2.19) low > 76
Serratia liquefaciens MT49 0.81 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.71 IAI46_03530 carboxylating nicotinate-nucleotide diphosphorylase low > 86
Pantoea sp. MT58 0.80 IAI47_06870 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.69 IAI47_15845 carboxylating nicotinate-nucleotide diphosphorylase low > 76
Erwinia tracheiphila SCR3 0.79 LU632_RS08690 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.69 LU632_RS03040 nadC carboxylating nicotinate-nucleotide diphosphorylase low > 74
Pectobacterium carotovorum WPP14 0.79 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.69 HER17_RS03250 carboxylating nicotinate-nucleotide diphosphorylase low > 75
Dickeya dadantii 3937 0.77 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.68 DDA3937_RS17955 carboxylating nicotinate-nucleotide diphosphorylase low > 74
Dickeya dianthicola ME23 0.77 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.67 DZA65_RS19035 carboxylating nicotinate-nucleotide diphosphorylase low > 75
Dickeya dianthicola 67-19 0.76 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.67 HGI48_RS17890 carboxylating nicotinate-nucleotide diphosphorylase low > 71
Herbaspirillum seropedicae SmR1 0.68 HSERO_RS07650 multidrug transporter 0.40 HSERO_RS11070 nicotinate-nucleotide pyrophosphorylase low > 78
Ralstonia solanacearum IBSBF1503 0.65 RALBFv3_RS18120 multidrug transporter subunit MdtB 0.41 RALBFv3_RS04730 nicotinate-nucleotide diphosphorylase (carboxylating) low > 76
Ralstonia solanacearum UW163 0.65 UW163_RS21010 multidrug transporter subunit MdtB 0.41 UW163_RS08940 nicotinate-nucleotide diphosphorylase (carboxylating) — —
Ralstonia solanacearum PSI07 0.65 RPSI07_RS05515 multidrug transporter subunit MdtB 0.42 RPSI07_RS12655 nicotinate-nucleotide diphosphorylase (carboxylating) low > 81
Ralstonia solanacearum GMI1000 0.65 RS_RS22915 multidrug transporter subunit MdtB 0.39 RS_RS12290 nicotinate-nucleotide diphosphorylase (carboxylating) low > 80
Ralstonia sp. UNC404CL21Col 0.65 ABZR87_RS19025 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.41 ABZR87_RS00350 carboxylating nicotinate-nucleotide diphosphorylase low > 80
Cupriavidus basilensis FW507-4G11 0.64 RR42_RS03310 multidrug transporter 0.39 RR42_RS17015 nicotinate-nucleotide pyrophosphorylase low > 128
Pseudomonas sp. RS175 0.63 PFR28_02194 Multidrug resistance protein MdtB 0.50 PFR28_00098 Nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 88
Pseudomonas fluorescens FW300-N2C3 0.62 AO356_25875 multidrug transporter 0.48 AO356_07370 nicotinate-nucleotide pyrophosphorylase low > 104
Pseudomonas fluorescens FW300-N2E2 0.62 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein 0.48 Pf6N2E2_3346 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 103
Pseudomonas putida KT2440 0.62 PP_3584 multidrug efflux transport system - membrane subunit 0.49 PP_0787 quinolinate phosphoribosyltransferase (decarboxylating) monomer low > 96
Rahnella sp. WP5 0.62 EX31_RS13380 MMPL family transporter 0.74 EX31_RS03515 carboxylating nicotinate-nucleotide diphosphorylase low > 89
Pseudomonas sp. S08-1 0.62 OH686_00925 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.47 OH686_16520 nicotinate-nucleotide diphosphorylase (carboxylating) low > 80
Pseudomonas fluorescens GW456-L13 0.62 PfGW456L13_3266 Acriflavin resistance plasma membrane protein 0.47 PfGW456L13_5082 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 87
Pseudomonas fluorescens FW300-N2E3 0.62 AO353_22895 multidrug transporter 0.50 AO353_05520 nicotinate-nucleotide pyrophosphorylase low > 101
Pseudomonas fluorescens SBW25-INTG 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.49 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase low > 109
Pseudomonas fluorescens SBW25 0.61 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.49 PFLU_RS03970 carboxylating nicotinate-nucleotide diphosphorylase low > 109
Pseudomonas simiae WCS417 0.61 PS417_12745 multidrug transporter 0.48 PS417_03925 nicotinate-nucleotide pyrophosphorylase low > 88
Pseudomonas fluorescens FW300-N1B4 0.61 Pf1N1B4_4665 Acriflavin resistance plasma membrane protein 0.48 Pf1N1B4_1153 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 87
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.38 QEN71_RS03065 carboxylating nicotinate-nucleotide diphosphorylase low > 153
Paraburkholderia bryophila 376MFSha3.1 0.59 H281DRAFT_06492 multidrug efflux pump 0.38 H281DRAFT_04070 nicotinate-nucleotide pyrophosphorylase [carboxylating] low > 103
Acidovorax sp. GW101-3H11 0.59 Ac3H11_3618 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.40 Ac3H11_3838 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 79
Pseudomonas syringae pv. syringae B728a 0.59 Psyr_2483 Acriflavin resistance protein 0.51 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) 0.27 64
Pseudomonas syringae pv. syringae B728a ΔmexB 0.59 Psyr_2483 Acriflavin resistance protein 0.51 Psyr_0815 nicotinate-nucleotide pyrophosphorylase (carboxylating) low > 86
Pseudomonas stutzeri RCH2 0.59 Psest_2139 Cation/multidrug efflux pump 0.52 Psest_0718 nicotinate-nucleotide pyrophosphorylase low > 67
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS07785 multidrug transporter 0.38 BPHYT_RS15645 nicotinate-nucleotide pyrophosphorylase low > 109
Paraburkholderia graminis OAS925 0.58 ABIE53_001783 multidrug efflux pump 0.40 ABIE53_003293 nicotinate-nucleotide pyrophosphorylase (carboxylating) low > 113
Castellaniella sp019104865 MT123 0.57 ABCV34_RS14620 multidrug efflux RND transporter permease subunit 0.39 ABCV34_RS03695 carboxylating nicotinate-nucleotide diphosphorylase low > 48
Variovorax sp. SCN45 0.56 GFF6659 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) 0.36 GFF2574 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.55 GFF487 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA 0.41 GFF1217 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 90
Variovorax sp. OAS795 0.54 ABID97_RS20855 efflux RND transporter permease subunit 0.38 ABID97_RS07410 carboxylating nicotinate-nucleotide diphosphorylase 0.29 58
Azospirillum sp. SherDot2 0.53 MPMX19_05477 Multidrug resistance protein MdtB 0.31 MPMX19_05672 putative nicotinate-nucleotide pyrophosphorylase [carboxylating] — —
Magnetospirillum magneticum AMB-1 0.52 AMB_RS17370 acriflavine resistance protein B 0.34 AMB_RS19655 nicotinate-nucleotide diphosphorylase (carboxylating) — —
Rhodanobacter denitrificans FW104-10B01 0.50 LRK54_RS09845 efflux RND transporter permease subunit 0.45 LRK54_RS13795 carboxylating nicotinate-nucleotide diphosphorylase low > 59
Rhodanobacter denitrificans MT42 0.50 LRK55_RS09505 efflux RND transporter permease subunit 0.45 LRK55_RS13510 carboxylating nicotinate-nucleotide diphosphorylase low > 63
Dyella japonica UNC79MFTsu3.2 0.50 ABZR86_RS16320 efflux RND transporter permease subunit 0.45 ABZR86_RS09850 carboxylating nicotinate-nucleotide diphosphorylase low > 74
Xanthomonas campestris pv. campestris strain 8004 0.49 Xcc-8004.4792.1 Acriflavin resistance protein 0.35 Xcc-8004.2009.1 Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) low > 74
Rhodopseudomonas palustris CGA009 0.49 TX73_013310 efflux RND transporter permease subunit 0.35 TX73_005415 carboxylating nicotinate-nucleotide diphosphorylase — —
Bacteroides thetaiotaomicron VPI-5482 0.25 BT2252 multidrug efflux membrane fusion protein (NCBI ptt file) 0.30 BT1560 nicotinate-nucleotide pyrophosphorylase (NCBI ptt file) — —
Parabacteroides merdae CL09T00C40 0.24 HMPREF1078_RS05470 efflux RND transporter permease subunit 0.32 HMPREF1078_RS16725 carboxylating nicotinate-nucleotide diphosphorylase — —
Phaeobacter inhibens DSM 17395 0.13 PGA1_78p00510 multidrug transporter MdtB 0.28 PGA1_c27810 nicotinate-nucleotide pyrophosphorylase low > 62

Not shown: 1 genomes with orthologs for BNILDI_14455 only; 33 genomes with orthologs for BNILDI_08735 only