Conservation of cofitness between Atu0205 and Atu3732 in Agrobacterium fabrum C58

52 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Agrobacterium fabrum C58 1.0 Atu0205 methylmalonate-semialdehyde dehydrogenase 1.0 Atu3732 hemolysin 0.39 6
Rhizobium sp. OAE497 0.88 ABIE40_RS03335 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.73 ABIE40_RS21835 hemolysin family protein low > 107
Sinorhizobium meliloti 1021 0.84 SMc00781 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from data) 0.41 SMc00240 hypothetical protein low > 103
Rhodopseudomonas palustris CGA009 0.72 TX73_017860 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.53 TX73_014560 hemolysin family protein 0.44 37
Bosea sp. OAE506 0.71 ABIE41_RS23920 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.63 ABIE41_RS13905 hemolysin family protein low > 77
Azospirillum sp. SherDot2 0.71 MPMX19_05423 Putative 3-oxopropanoate dehydrogenase 0.41 MPMX19_06247 hypothetical protein low > 112
Rhodospirillum rubrum S1H 0.66 Rru_A2071 Methylmalonate-semialdehyde dehydrogenase (NCBI) 0.40 Rru_A0756 hypothetical protein (NCBI) low > 58
Dinoroseobacter shibae DFL-12 0.66 Dshi_1747 methylmalonate-semialdehyde dehydrogenase (RefSeq) 0.59 Dshi_3672 protein of unknown function DUF21 (RefSeq) low > 64
Phaeobacter inhibens DSM 17395 0.65 PGA1_c17300 methylmalonate-semialdehyde dehydrogenase 0.19 PGA1_c14050 inner membrane protein — —
Mycobacterium tuberculosis H37Rv 0.65 Rv0753c Probable methylmalonate-semialdehyde dehydrogenase MmsA (methylmalonic acid semialdehyde dehydrogenase) (MMSDH) 0.14 Rv1842c Conserved hypothetical membrane protein low > 58
Brevundimonas sp. GW460-12-10-14-LB2 0.63 A4249_RS03580 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.37 A4249_RS08175 hemolysin family protein low > 48
Sphingomonas koreensis DSMZ 15582 0.62 Ga0059261_3677 methylmalonic acid semialdehyde dehydrogenase 0.46 Ga0059261_1443 Hemolysins and related proteins containing CBS domains low > 68
Caulobacter crescentus NA1000 Δfur 0.61 CCNA_02357 methylmalonic acid semialdehyde dehydrogenase 0.37 CCNA_00369 magnesium and cobalt efflux protein corC-like protein low > 67
Caulobacter crescentus NA1000 0.61 CCNA_02357 methylmalonic acid semialdehyde dehydrogenase 0.37 CCNA_00369 magnesium and cobalt efflux protein corC-like protein low > 66
Alteromonas macleodii MIT1002 0.60 MIT1002_03326 Methylmalonate-semialdehyde dehydrogenase [acylating] 0.15 MIT1002_01294 Hemolysin C low > 70
Shewanella loihica PV-4 0.59 Shew_0965 methylmalonate-semialdehyde dehydrogenase (RefSeq) 0.22 Shew_0284 hypothetical protein (RefSeq) low > 60
Shewanella amazonensis SB2B 0.59 Sama_2650 methylmalonate-semialdehyde dehydrogenase (RefSeq) 0.22 Sama_3284 hemolysin, putative (RefSeq) low > 62
Paraburkholderia graminis OAS925 0.57 ABIE53_005233 malonate-semialdehyde dehydrogenase (acetylating)/methylmalonate-semialdehyde dehydrogenase 0.16 ABIE53_003593 Mg2+/Co2+ transporter CorB low > 113
Shewanella sp. ANA-3 0.57 Shewana3_3107 methylmalonate-semialdehyde dehydrogenase [acylating] (RefSeq) 0.21 Shewana3_0353 hypothetical protein (RefSeq) low > 73
Paraburkholderia bryophila 376MFSha3.1 0.57 H281DRAFT_03264 methylmalonate-semialdehyde dehydrogenase [acylating] 0.15 H281DRAFT_06258 Mg2+ and Co2+ transporter CorB, contains DUF21, CBS pair, and CorC-HlyC domains low > 103
Pseudomonas stutzeri RCH2 0.56 Psest_3781 methylmalonic acid semialdehyde dehydrogenase 0.16 Psest_3136 Putative Mg2+ and Co2+ transporter CorB low > 67
Variovorax sp. OAS795 0.55 ABID97_RS19485 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.26 ABID97_RS21945 hemolysin family protein low > 91
Burkholderia phytofirmans PsJN 0.55 BPHYT_RS28825 methylmalonate-semialdehyde dehydrogenase 0.16 BPHYT_RS17140 magnesium and cobalt efflux protein CorC low > 109
Pseudomonas fluorescens FW300-N1B4 0.55 Pf1N1B4_1238 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) 0.13 Pf1N1B4_2042 Phosphate regulon metal ion transporter containing CBS domains low > 87
Pseudomonas fluorescens GW456-L13 0.55 PfGW456L13_2 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) 0.13 PfGW456L13_760 Phosphate regulon metal ion transporter containing CBS domains low > 87
Pseudomonas fluorescens FW300-N2E3 0.55 AO353_06080 methylmalonate-semialdehyde dehydrogenase 0.13 AO353_09865 hypothetical protein low > 101
Dickeya dadantii 3937 0.55 DDA3937_RS03670 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.22 DDA3937_RS17170 HlyC/CorC family transporter low > 74
Dickeya dianthicola ME23 0.54 DZA65_RS03855 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.22 DZA65_RS18310 HlyC/CorC family transporter low > 75
Paraburkholderia sabiae LMG 24235 0.54 QEN71_RS29405 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.17 QEN71_RS27300 HlyC/CorC family transporter low > 153
Variovorax sp. SCN45 0.54 GFF5041 Malonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.18) 0.28 GFF1937 Hemolysins and related proteins containing CBS domains low > 127
Dickeya dianthicola 67-19 0.54 HGI48_RS03730 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.22 HGI48_RS17225 HlyC/CorC family transporter low > 71
Azospirillum brasilense Sp245 0.54 AZOBR_RS22500 methylmalonate-semialdehyde dehydrogenase 0.37 AZOBR_RS16970 hypothetical protein low > 97
Cupriavidus basilensis FW507-4G11 0.54 RR42_RS01580 methylmalonate-semialdehyde dehydrogenase 0.31 RR42_RS28885 membrane protein low > 128
Ralstonia solanacearum GMI1000 0.54 RS_RS22225 methylmalonate-semialdehyde dehydrogenase (CoA acylating) 0.20 RS_RS11430 HlyC/CorC family transporter low > 80
Enterobacter sp. TBS_079 0.54 MPMX20_03375 Putative 3-oxopropanoate dehydrogenase 0.22 MPMX20_00495 hypothetical protein low > 85
Ralstonia solanacearum PSI07 0.54 RPSI07_RS04870 methylmalonate-semialdehyde dehydrogenase (CoA acylating) 0.20 RPSI07_RS13270 HlyC/CorC family transporter low > 81
Ralstonia sp. UNC404CL21Col 0.53 ABZR87_RS19665 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.19 ABZR87_RS15885 hemolysin family protein low > 80
Ralstonia solanacearum UW163 0.53 UW163_RS20405 methylmalonate-semialdehyde dehydrogenase (CoA acylating) 0.20 UW163_RS09720 HlyC/CorC family transporter — —
Ralstonia solanacearum IBSBF1503 0.53 RALBFv3_RS18725 methylmalonate-semialdehyde dehydrogenase (CoA acylating) 0.20 RALBFv3_RS03950 HlyC/CorC family transporter low > 76
Herbaspirillum seropedicae SmR1 0.53 HSERO_RS23245 methylmalonate-semialdehyde dehydrogenase 0.21 HSERO_RS08405 membrane protein low > 78
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.53 GFF888 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) 0.22 GFF871 Putative membrane protein low > 78
Hydrogenophaga sp. GW460-11-11-14-LB1 0.53 GFF1895 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) 0.33 GFF4625 Magnesium and cobalt efflux protein CorC low > 90
Enterobacter asburiae PDN3 0.53 EX28DRAFT_0147 methylmalonic acid semialdehyde dehydrogenase 0.22 EX28DRAFT_3404 Hemolysins and related proteins containing CBS domains low > 76
Pectobacterium carotovorum WPP14 0.53 HER17_RS14440 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.23 HER17_RS03970 hemolysin family protein low > 75
Acidovorax sp. GW101-3H11 0.52 Ac3H11_4340 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) 0.33 Ac3H11_827 Magnesium and cobalt efflux protein CorC low > 79
Serratia liquefaciens MT49 0.51 IAI46_24020 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.22 IAI46_01760 HlyC/CorC family transporter low > 86
Marinobacter adhaerens HP15 0.51 HP15_2655 methylmalonate-semialdehyde dehydrogenase 0.17 HP15_755 Mg2+ and Co2+ transporter CorB low > 73
Pantoea sp. MT58 0.50 IAI47_01465 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.20 IAI47_02710 HlyC/CorC family transporter low > 76
Klebsiella michiganensis M5al 0.50 BWI76_RS03070 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) (from data) 0.22 BWI76_RS02765 membrane protein low > 92
Erwinia tracheiphila SCR3 0.50 LU632_RS02350 CoA-acylating methylmalonate-semialdehyde dehydrogenase 0.20 LU632_RS02100 hemolysin family protein low > 74
Acinetobacter radioresistens SK82 0.46 MPMX26_01550 Methylmalonate-semialdehyde dehydrogenase [acylating] 0.22 MPMX26_02321 hypothetical protein — —
Shewanella oneidensis MR-1 0.44 SO1678 mmsA methylmalonate-semialdehyde dehydrogenase (NCBI ptt file) 0.34 SO2815 CBS domain protein (NCBI ptt file) low > 76
Xanthomonas campestris pv. campestris strain 8004 0.41 Xcc-8004.3689.1 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) 0.36 Xcc-8004.3156.1 Magnesium and cobalt efflux protein CorC low > 74

Not shown: 11 genomes with orthologs for Atu0205 only; 38 genomes with orthologs for Atu3732 only