Conservation of cofitness between ABZR87_RS11225 and ABZR87_RS19025 in Ralstonia sp. UNC404CL21Col

67 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Ralstonia sp. UNC404CL21Col 1.0 ABZR87_RS11225 DHA2 family efflux MFS transporter permease subunit 1.0 ABZR87_RS19025 MdtB/MuxB family multidrug efflux RND transporter permease subunit 0.41 16
Ralstonia solanacearum IBSBF1503 0.94 RALBFv3_RS15695 MFS transporter 0.91 RALBFv3_RS18120 multidrug transporter subunit MdtB low > 76
Ralstonia solanacearum GMI1000 0.92 RS_RS06475 MFS transporter 0.92 RS_RS22915 multidrug transporter subunit MdtB low > 80
Ralstonia solanacearum PSI07 0.92 RPSI07_RS17660 MFS transporter 0.91 RPSI07_RS05515 multidrug transporter subunit MdtB low > 81
Cupriavidus basilensis FW507-4G11 0.80 RR42_RS12830 multidrug resistance protein B 0.78 RR42_RS03310 multidrug transporter low > 128
Paraburkholderia bryophila 376MFSha3.1 0.69 H281DRAFT_05107 MFS transporter, DHA2 family, multidrug resistance protein 0.66 H281DRAFT_06492 multidrug efflux pump low > 103
Paraburkholderia sabiae LMG 24235 0.69 QEN71_RS23085 DHA2 family efflux MFS transporter permease subunit 0.67 QEN71_RS23305 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 153
Paraburkholderia graminis OAS925 0.69 ABIE53_002458 DHA2 family multidrug resistance protein 0.65 ABIE53_001783 multidrug efflux pump low > 113
Burkholderia phytofirmans PsJN 0.67 BPHYT_RS08085 DSBA oxidoreductase 0.65 BPHYT_RS07785 multidrug transporter 0.16 101
Variovorax sp. SCN45 0.66 GFF4771 Multidrug efflux system EmrAB-OMF, inner-membrane proton/drug antiporter EmrB (MFS type) 0.59 GFF6659 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) low > 127
Hydrogenophaga sp. GW460-11-11-14-LB1 0.64 GFF3757 Inner membrane component of tripartite multidrug resistance system 0.59 GFF487 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA low > 90
Variovorax sp. OAS795 0.64 ABID97_RS20390 DHA2 family efflux MFS transporter permease subunit 0.57 ABID97_RS20855 efflux RND transporter permease subunit low > 91
Herbaspirillum seropedicae SmR1 0.64 HSERO_RS13575 DSBA oxidoreductase 0.77 HSERO_RS07650 multidrug transporter low > 78
Acidovorax sp. GW101-3H11 0.61 Ac3H11_2352 Inner membrane component of tripartite multidrug resistance system 0.66 Ac3H11_3618 Cobalt-zinc-cadmium resistance protein CzcA; Cation efflux system protein CusA low > 79
Castellaniella sp019104865 MT123 0.59 ABCV34_RS05950 DHA2 family efflux MFS transporter permease subunit 0.57 ABCV34_RS14620 multidrug efflux RND transporter permease subunit low > 48
Enterobacter sp. TBS_079 0.56 MPMX20_03564 Multidrug export protein EmrB 0.65 MPMX20_03061 Multidrug resistance protein MdtB low > 85
Enterobacter asburiae PDN3 0.56 EX28DRAFT_2769 drug resistance transporter, EmrB/QacA subfamily 0.65 EX28DRAFT_0483 Cation/multidrug efflux pump low > 76
Rhodospirillum rubrum S1H 0.56 Rru_A0858 Drug resistance transporter EmrB/QacA subfamily (NCBI) 0.24 Rru_A2094 Acriflavin resistance protein (NCBI) low > 58
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.55 GFF1593 Multidrug resistance protein B 0.63 GFF3854 Multidrug transporter MdtB low > 78
Rahnella sp. WP5 0.55 EX31_RS13660 multidrug efflux MFS transporter permease subunit EmrB 0.65 EX31_RS13380 MMPL family transporter low > 89
Klebsiella michiganensis M5al 0.55 BWI76_RS22100 multidrug effux MFS transporter subunit EmrB 0.65 BWI76_RS19255 multidrug transporter subunit MdtB low > 92
Dickeya dianthicola ME23 0.55 DZA65_RS17910 multidrug efflux MFS transporter permease subunit EmrB 0.64 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 75
Dickeya dianthicola 67-19 0.55 HGI48_RS16835 multidrug efflux MFS transporter permease subunit EmrB 0.63 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 71
Pectobacterium carotovorum WPP14 0.55 HER17_RS04460 multidrug efflux MFS transporter permease subunit EmrB 0.65 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 75
Escherichia coli Nissle 1917 0.54 ECOLIN_RS14970 multidrug efflux MFS transporter permease subunit EmrB 0.63 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB low > 55
Dickeya dadantii 3937 0.54 DDA3937_RS16765 multidrug efflux MFS transporter permease subunit EmrB 0.64 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 74
Escherichia coli ECOR38 0.54 HEPCGN_19970 emrB multidrug efflux MFS transporter permease subunit EmrB 0.63 HEPCGN_02885 mdtB multidrug efflux RND transporter permease subunit MdtB low > 87
Escherichia coli ECRC102 0.54 NIAGMN_18545 emrB multidrug efflux MFS transporter permease subunit EmrB 0.63 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB — —
Escherichia coli BL21 0.54 ECD_02541 multidrug efflux system protein 0.63 ECD_01980 multidrug efflux system, subunit B low > 61
Escherichia coli ECRC98 0.54 JDDGAC_24440 emrB multidrug efflux MFS transporter permease subunit EmrB 0.63 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB low > 86
Escherichia coli BW25113 0.54 b2686 emrB multidrug efflux system protein (NCBI) 0.63 b2075 mdtB multidrug efflux system, subunit B (NCBI) low > 76
Escherichia coli ECRC101 0.54 MCAODC_11300 emrB multidrug efflux MFS transporter permease subunit EmrB 0.63 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB low > 87
Escherichia coli ECOR27 0.54 NOLOHH_12615 emrB multidrug efflux MFS transporter permease subunit EmrB 0.64 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB low > 75
Escherichia coli ECRC100 0.54 OKFHMN_20775 emrB multidrug efflux MFS transporter permease subunit EmrB 0.63 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB low > 80
Escherichia fergusonii Becca 0.54 EFB2_01242 Multidrug export protein EmrB 0.63 EFB2_01780 Multidrug resistance protein MdtB low > 86
Escherichia coli ECRC62 0.54 BNILDI_11175 emrB multidrug efflux MFS transporter permease subunit EmrB 0.63 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB low > 75
Escherichia coli HS(pFamp)R (ATCC 700891) 0.54 OHPLBJKB_01047 Multidrug export protein EmrB 0.63 OHPLBJKB_01629 Multidrug resistance protein MdtB low > 73
Escherichia coli ECRC99 0.54 KEDOAH_07360 emrB multidrug efflux MFS transporter permease subunit EmrB 0.63 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB — —
Pantoea sp. MT58 0.54 IAI47_04495 multidrug efflux MFS transporter permease subunit EmrB 0.63 IAI47_16895 efflux RND transporter permease subunit low > 76
Serratia liquefaciens MT49 0.53 IAI46_20005 multidrug efflux MFS transporter permease subunit EmrB 0.65 IAI46_18975 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 86
Rhodanobacter denitrificans MT42 0.50 LRK55_RS15865 DHA2 family efflux MFS transporter permease subunit 0.50 LRK55_RS09505 efflux RND transporter permease subunit low > 63
Rhodanobacter denitrificans FW104-10B01 0.50 LRK54_RS16115 DHA2 family efflux MFS transporter permease subunit 0.51 LRK54_RS09845 efflux RND transporter permease subunit low > 59
Rhodanobacter sp. FW510-T8 0.48 OKGIIK_08535 emrB MFS transporter 0.50 OKGIIK_16105 acrB Multidrug efflux pump subunit AcrB low > 52
Dyella japonica UNC79MFTsu3.2 0.47 ABZR86_RS14765 DHA2 family efflux MFS transporter permease subunit 0.50 ABZR86_RS16320 efflux RND transporter permease subunit low > 74
Pseudomonas fluorescens GW456-L13 0.46 PfGW456L13_2606 Inner membrane component of tripartite multidrug resistance system 0.68 PfGW456L13_3266 Acriflavin resistance plasma membrane protein low > 87
Pseudomonas putida KT2440 0.46 PP_3548 multidrug efflux transport system - permease subunit 0.68 PP_3584 multidrug efflux transport system - membrane subunit low > 96
Pseudomonas fluorescens FW300-N2C3 0.46 AO356_01025 multidrug resistance protein B 0.68 AO356_25875 multidrug transporter low > 104
Pseudomonas sp. RS175 0.46 PFR28_02747 Multidrug export protein EmrB 0.68 PFR28_02194 Multidrug resistance protein MdtB low > 88
Pseudomonas fluorescens FW300-N1B4 0.46 Pf1N1B4_4002 Inner membrane component of tripartite multidrug resistance system 0.67 Pf1N1B4_4665 Acriflavin resistance plasma membrane protein low > 87
Pseudomonas fluorescens SBW25 0.45 PFLU_RS18895 DHA2 family efflux MFS transporter permease subunit 0.67 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 109
Pseudomonas fluorescens SBW25-INTG 0.45 PFLU_RS18895 DHA2 family efflux MFS transporter permease subunit 0.67 PFLU_RS13430 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 109
Pseudomonas fluorescens FW300-N2E3 0.45 AO353_27840 multidrug resistance protein B 0.68 AO353_22895 multidrug transporter low > 101
Pseudomonas simiae WCS417 0.45 PS417_16910 multidrug resistance protein B 0.67 PS417_12745 multidrug transporter low > 88
Pseudomonas fluorescens FW300-N2E2 0.45 Pf6N2E2_149 Inner membrane component of tripartite multidrug resistance system 0.68 Pf6N2E2_1272 Acriflavin resistance plasma membrane protein low > 103
Pseudomonas syringae pv. syringae B728a ΔmexB 0.44 Psyr_1731 Drug resistance transporter EmrB/QacA subfamily 0.65 Psyr_2483 Acriflavin resistance protein low > 86
Pseudomonas syringae pv. syringae B728a 0.44 Psyr_1731 Drug resistance transporter EmrB/QacA subfamily 0.65 Psyr_2483 Acriflavin resistance protein low > 86
Rhodopseudomonas palustris CGA009 0.44 TX73_019160 DHA2 family efflux MFS transporter permease subunit 0.52 TX73_013310 efflux RND transporter permease subunit low > 86
Xanthomonas campestris pv. campestris strain 8004 0.44 Xcc-8004.3524.1 Inner membrane component of tripartite multidrug resistance system 0.50 Xcc-8004.4792.1 Acriflavin resistance protein low > 74
Mucilaginibacter yixingensis YX-36 DSM 26809 0.34 ABZR88_RS20975 DHA2 family efflux MFS transporter permease subunit 0.24 ABZR88_RS19050 efflux RND transporter permease subunit low > 71
Pedobacter sp. GW460-11-11-14-LB5 0.32 CA265_RS21345 MFS transporter 0.24 CA265_RS17650 acriflavin resistance protein low > 88
Desulfovibrio vulgaris Miyazaki F 0.32 DvMF_1099 drug resistance transporter, EmrB/QacA subfamily (RefSeq) 0.45 DvMF_1515 acriflavin resistance protein (RefSeq) low > 51
Azospirillum sp. SherDot2 0.30 MPMX19_05353 Fatty acid resistance protein FarB 0.57 MPMX19_05477 Multidrug resistance protein MdtB low > 112
Erwinia tracheiphila SCR3 0.30 LU632_RS09490 DHA2 family efflux MFS transporter permease subunit 0.64 LU632_RS08690 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 74
Magnetospirillum magneticum AMB-1 0.23 AMB_RS20240 MFS transporter 0.56 AMB_RS17370 acriflavine resistance protein B low > 64
Bosea sp. OAE506 0.23 ABIE41_RS08465 DHA2 family efflux MFS transporter permease subunit 0.43 ABIE41_RS20140 efflux RND transporter permease subunit low > 77
Sinorhizobium meliloti 1021 0.22 SMc03167 multidrug efflux system protein 0.21 SMc01457 transport transmembrane protein low > 103
Pseudomonas sp. S08-1 0.22 OH686_04570 Inner-membrane proton/drug antiporter (MSF type) of tripartite multidrug efflux system 0.69 OH686_00925 Multidrug efflux system MdtABC-TolC, inner-membrane proton/drug antiporter MdtB (RND type) low > 80
Ralstonia solanacearum UW163 0.18 UW163_RS07870 MFS transporter 0.91 UW163_RS21010 multidrug transporter subunit MdtB — —

Not shown: 14 genomes with orthologs for ABZR87_RS11225 only; 4 genomes with orthologs for ABZR87_RS19025 only