Conservation of cofitness between BT1115 and BT2252 in Bacteroides thetaiotaomicron VPI-5482

65 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Bacteroides thetaiotaomicron VPI-5482 1.0 BT1115 aldo/keto reductase (NCBI ptt file) 1.0 BT2252 multidrug efflux membrane fusion protein (NCBI ptt file) 0.22 12
Parabacteroides merdae CL09T00C40 1.00 HMPREF1078_RS08255 aldo/keto reductase 0.76 HMPREF1078_RS05470 efflux RND transporter permease subunit low > 61
Phocaeicola vulgatus CL09T03C04 0.94 HMPREF1058_RS05460 aldo/keto reductase 0.86 HMPREF1058_RS13825 efflux RND transporter permease subunit low > 67
Phocaeicola dorei CL03T12C01 0.58 ABI39_RS19255 aldo/keto reductase 0.86 ABI39_RS09435 efflux RND transporter permease subunit low > 72
Serratia liquefaciens MT49 0.40 IAI46_16480 aldo/keto reductase 0.25 IAI46_18980 multidrug efflux RND transporter permease subunit MdtC low > 86
Rhodanobacter sp. FW510-T8 0.39 OKGIIK_07780 Aldehyde oxidase 0.28 OKGIIK_11990 acrB acriflavine resistance protein B low > 52
Escherichia coli Nissle 1917 0.39 ECOLIN_RS26205 aldo/keto reductase 0.25 ECOLIN_RS12200 multidrug efflux RND transporter permease subunit MdtB — —
Escherichia fergusonii Becca 0.39 EFB2_03742 Aldo-keto reductase IolS 0.25 EFB2_01780 Multidrug resistance protein MdtB low > 86
Xanthomonas campestris pv. campestris strain 8004 0.38 Xcc-8004.1797.1 Aldo-keto reductase 0.34 Xcc-8004.1262.1 RND multidrug efflux transporter; Acriflavin resistance protein low > 74
Rahnella sp. WP5 0.38 EX31_RS20825 aldo/keto reductase 0.25 EX31_RS13380 MMPL family transporter low > 89
Agrobacterium fabrum C58 0.38 Atu0260 aldo-keto reductase 0.31 Atu2054 AcrB/AcrD/AcrF family protein low > 89
Pedobacter sp. GW460-11-11-14-LB5 0.37 CA265_RS00435 aldo/keto reductase 0.53 CA265_RS17650 acriflavin resistance protein low > 88
Echinicola vietnamensis KMM 6221, DSM 17526 0.37 Echvi_4177 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) 0.58 Echvi_0681 Cation/multidrug efflux pump low > 79
Ralstonia solanacearum GMI1000 0.36 RS_RS01075 aldo/keto reductase 0.27 RS_RS22920 nodulation protein low > 80
Ralstonia solanacearum UW163 0.36 UW163_RS23080 aldo/keto reductase 0.27 UW163_RS21015 nodulation protein — —
Ralstonia solanacearum IBSBF1503 0.36 RALBFv3_RS22535 aldo/keto reductase 0.27 RALBFv3_RS18115 nodulation protein low > 76
Mucilaginibacter yixingensis YX-36 DSM 26809 0.36 ABZR88_RS08510 aldo/keto reductase 0.52 ABZR88_RS19050 efflux RND transporter permease subunit low > 71
Caulobacter crescentus NA1000 Δfur 0.35 CCNA_03097 aldo/keto reductase family protein 0.27 CCNA_01262 cation/multidrug efflux pump, AcrB family low > 67
Caulobacter crescentus NA1000 0.35 CCNA_03097 aldo/keto reductase family protein 0.27 CCNA_01262 cation/multidrug efflux pump, AcrB family low > 66
Sinorhizobium meliloti 1021 0.35 SMa0563 aldehyde or keto oxidase 0.31 SMc01457 transport transmembrane protein low > 103
Pectobacterium carotovorum WPP14 0.35 HER17_RS13685 aldo/keto reductase 0.25 HER17_RS06320 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 75
Ralstonia solanacearum PSI07 0.34 RPSI07_RS00620 aldo/keto reductase 0.27 RPSI07_RS05520 nodulation protein low > 81
Rhizobium sp. OAE497 0.34 ABIE40_RS26495 aldo/keto reductase 0.31 ABIE40_RS11655 efflux RND transporter permease subunit low > 107
Brevundimonas sp. GW460-12-10-14-LB2 0.33 A4249_RS07260 aldo/keto reductase 0.30 A4249_RS07780 efflux RND transporter permease subunit low > 48
Pontibacter actiniarum KMM 6156, DSM 19842 0.33 CA264_05950 aldo/keto reductase 0.57 CA264_13040 acriflavin resistance protein low > 74
Dickeya dadantii 3937 0.32 DDA3937_RS03195 aldo/keto reductase 0.26 DDA3937_RS15265 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 74
Pseudomonas simiae WCS417 0.32 PS417_14445 aldo/keto reductase 0.31 PS417_22755 acriflavine resistance protein B low > 88
Herbaspirillum seropedicae SmR1 0.32 HSERO_RS16785 aldo/keto reductase 0.26 HSERO_RS07655 nodulation protein low > 78
Pseudomonas fluorescens FW300-N1B4 0.32 Pf1N1B4_4693 Oxidoreductase 0.32 Pf1N1B4_720 RND multidrug efflux transporter; Acriflavin resistance protein low > 87
Dickeya dianthicola 67-19 0.32 HGI48_RS03345 aldo/keto reductase 0.25 HGI48_RS15345 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 71
Pseudomonas fluorescens FW300-N2E3 0.32 AO353_23805 aldo/keto reductase 0.31 AO353_04000 acriflavine resistance protein B low > 101
Dickeya dianthicola ME23 0.32 DZA65_RS03390 aldo/keto reductase 0.25 DZA65_RS16165 MdtB/MuxB family multidrug efflux RND transporter permease subunit low > 75
Pseudomonas fluorescens SBW25-INTG 0.31 PFLU_RS16375 aldo/keto reductase 0.31 PFLU_RS24405 multidrug efflux RND transporter permease subunit low > 109
Pseudomonas fluorescens SBW25 0.31 PFLU_RS16375 aldo/keto reductase 0.31 PFLU_RS24405 multidrug efflux RND transporter permease subunit low > 109
Pseudomonas fluorescens FW300-N2C3 0.31 AO356_23370 aldo/keto reductase 0.31 AO356_18440 acriflavine resistance protein B low > 104
Acidovorax sp. GW101-3H11 0.31 Ac3H11_647 Aldo/keto reductase 0.38 Ac3H11_482 RND multidrug efflux transporter; Acriflavin resistance protein low > 79
Lysobacter sp. OAE881 0.31 ABIE51_RS11290 aldo/keto reductase 0.35 ABIE51_RS16985 efflux RND transporter permease subunit low > 62
Castellaniella sp019104865 MT123 0.31 ABCV34_RS02780 aldo/keto reductase 0.23 ABCV34_RS14620 multidrug efflux RND transporter permease subunit low > 48
Klebsiella michiganensis M5al 0.30 BWI76_RS21735 aldehyde oxidase 0.25 BWI76_RS19255 multidrug transporter subunit MdtB low > 92
Dyella japonica UNC79MFTsu3.2 0.30 ABZR86_RS16200 aldo/keto reductase 0.28 ABZR86_RS11745 efflux RND transporter permease subunit low > 74
Pseudomonas fluorescens FW300-N2E2 0.30 Pf6N2E2_1615 Aldo-keto reductase 0.30 Pf6N2E2_5614 RND multidrug efflux transporter; Acriflavin resistance protein low > 103
Rhodanobacter denitrificans MT42 0.30 LRK55_RS10155 aldo/keto reductase 0.28 LRK55_RS11630 efflux RND transporter permease subunit low > 63
Rhodanobacter denitrificans FW104-10B01 0.30 LRK54_RS10515 aldo/keto reductase 0.28 LRK54_RS11905 efflux RND transporter permease subunit low > 59
Cupriavidus basilensis FW507-4G11 0.30 RR42_RS20325 aldo/keto reductase 0.25 RR42_RS20555 acriflavine resistance protein B low > 128
Rhodopseudomonas palustris CGA009 0.30 TX73_015655 aldo/keto reductase 0.32 TX73_019545 MexW/MexI family multidrug efflux RND transporter permease subunit low > 86
Azospirillum sp. SherDot2 0.29 MPMX19_01216 Aldo-keto reductase IolS 0.40 MPMX19_04343 Efflux pump membrane transporter BepE low > 112
Magnetospirillum magneticum AMB-1 0.29 AMB_RS01300 aldo/keto reductase 0.30 AMB_RS17260 acriflavine resistance protein B low > 64
Rhodospirillum rubrum S1H 0.29 Rru_A1059 Aldo/keto reductase (NCBI) 0.33 Rru_A2094 Acriflavin resistance protein (NCBI) low > 58
Pseudomonas sp. RS175 0.29 PFR28_02364 Aldo-keto reductase YhdN 0.30 PFR28_03330 Multidrug efflux pump subunit AcrB low > 88
Hydrogenophaga sp. GW460-11-11-14-LB1 0.28 GFF3816 Aldo-keto reductase 0.37 GFF4261 RND multidrug efflux transporter; Acriflavin resistance protein low > 90
Enterobacter sp. TBS_079 0.27 MPMX20_00046 Aldo-keto reductase IolS 0.25 MPMX20_03061 Multidrug resistance protein MdtB low > 85
Pantoea sp. MT58 0.26 IAI47_08360 aldo/keto reductase 0.24 IAI47_16895 efflux RND transporter permease subunit low > 76
Variovorax sp. SCN45 0.24 GFF3107 Oxidoreductase, aldo/keto reductase family 0.30 GFF3509 Multidrug efflux system, inner membrane proton/drug antiporter (RND type) => MexI of MexHI-OpmD system low > 127
Paraburkholderia sabiae LMG 24235 0.24 QEN71_RS08125 aldo/keto reductase 0.28 QEN71_RS42075 efflux RND transporter permease subunit low > 153
Azospirillum brasilense Sp245 0.24 AZOBR_RS21420 aldo/keto reductase 0.40 AZOBR_RS22130 acriflavin resistance protein low > 97
Escherichia coli BW25113 0.19 b0419 yajO putative NAD(P)H-dependent xylose reductase (VIMSS) 0.25 b2075 mdtB multidrug efflux system, subunit B (NCBI) low > 76
Escherichia coli ECRC101 0.19 MCAODC_27650 yajO 1-deoxyxylulose-5-phosphate synthase YajO 0.25 MCAODC_20745 mdtB multidrug efflux RND transporter permease subunit MdtB — —
Escherichia coli ECRC101 0.19 OKFHMN_08425 yajO 1-deoxyxylulose-5-phosphate synthase YajO 0.25 OKFHMN_24195 mdtB multidrug efflux RND transporter permease subunit MdtB — —
Escherichia coli ECRC98 0.19 JDDGAC_12080 yajO 1-deoxyxylulose-5-phosphate synthase YajO 0.25 JDDGAC_28305 mdtB multidrug efflux RND transporter permease subunit MdtB — —
Escherichia coli ECRC102 0.19 NIAGMN_06480 yajO 1-deoxyxylulose-5-phosphate synthase YajO 0.25 NIAGMN_22140 mdtB multidrug efflux RND transporter permease subunit MdtB — —
Escherichia coli ECRC99 0.19 KEDOAH_19540 yajO 1-deoxyxylulose-5-phosphate synthase YajO 0.25 KEDOAH_03955 mdtB multidrug efflux RND transporter permease subunit MdtB — —
Escherichia coli ECRC62 0.19 BNILDI_22790 yajO 1-deoxyxylulose-5-phosphate synthase YajO 0.25 BNILDI_14455 mdtB multidrug efflux RND transporter permease subunit MdtB — —
Escherichia coli ECOR27 0.18 NOLOHH_01375 yajO 1-deoxyxylulose-5-phosphate synthase YajO 0.25 NOLOHH_15540 mdtB multidrug efflux RND transporter permease subunit MdtB low > 57
Escherichia coli BL21 0.18 ECD_00367 2-carboxybenzaldehyde reductase 0.25 ECD_01980 multidrug efflux system, subunit B low > 60
Escherichia coli HS(pFamp)R (ATCC 700891) 0.18 OHPLBJKB_03257 Aldo-keto reductase IolS 0.25 OHPLBJKB_01629 Multidrug resistance protein MdtB low > 73
Enterobacter asburiae PDN3 0.18 EX28DRAFT_2552 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) 0.25 EX28DRAFT_0483 Cation/multidrug efflux pump 0.42 47

Not shown: 6 genomes with orthologs for BT1115 only; 20 genomes with orthologs for BT2252 only