Conservation of cofitness between b1849 and b2903 in Escherichia coli BW25113

65 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli BW25113 1.0 b1849 purT phosphoribosylglycinamide formyltransferase 2 (NCBI) 1.0 b2903 gcvP glycine dehydrogenase (NCBI) 0.21 4
Escherichia coli ECRC62 0.99 BNILDI_15655 purT formate-dependent phosphoribosylglycinamide formyltransferase 1.00 BNILDI_09980 gcvP aminomethyl-transferring glycine dehydrogenase — —
Escherichia coli BL21 0.99 ECD_01820 phosphoribosylglycinamide formyltransferase 2 1.00 ECD_02735 glycine decarboxylase, PLP-dependent, subunit P of glycine cleavage complex low > 60
Escherichia coli ECOR27 0.99 NOLOHH_16860 purT formate-dependent phosphoribosylglycinamide formyltransferase 0.99 NOLOHH_11445 gcvP aminomethyl-transferring glycine dehydrogenase — —
Escherichia coli HS(pFamp)R (ATCC 700891) 0.99 OHPLBJKB_01880 Formate-dependent phosphoribosylglycinamide formyltransferase 1.00 OHPLBJKB_00812 Glycine dehydrogenase (decarboxylating) low > 73
Escherichia coli ECRC98 0.99 JDDGAC_00925 purT formate-dependent phosphoribosylglycinamide formyltransferase 1.00 JDDGAC_23170 gcvP aminomethyl-transferring glycine dehydrogenase — —
Escherichia coli ECRC101 0.99 MCAODC_19055 purT formate-dependent phosphoribosylglycinamide formyltransferase 1.00 MCAODC_10050 gcvP aminomethyl-transferring glycine dehydrogenase — —
Escherichia fergusonii Becca 0.99 EFB2_02094 Formate-dependent phosphoribosylglycinamide formyltransferase 0.99 EFB2_00999 Glycine dehydrogenase (decarboxylating) low > 86
Escherichia coli ECOR38 0.99 HEPCGN_04755 purT formate-dependent phosphoribosylglycinamide formyltransferase 1.00 HEPCGN_18820 gcvP aminomethyl-transferring glycine dehydrogenase low > 85
Escherichia coli ECRC99 0.99 KEDOAH_01755 purT formate-dependent phosphoribosylglycinamide formyltransferase 1.00 KEDOAH_08610 gcvP aminomethyl-transferring glycine dehydrogenase — —
Escherichia coli ECRC102 0.99 NIAGMN_01710 purT formate-dependent phosphoribosylglycinamide formyltransferase 1.00 NIAGMN_17295 gcvP aminomethyl-transferring glycine dehydrogenase — —
Escherichia coli ECRC101 0.99 OKFHMN_26350 purT formate-dependent phosphoribosylglycinamide formyltransferase 1.00 OKFHMN_19530 gcvP aminomethyl-transferring glycine dehydrogenase — —
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.88 GFF1628 Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) 0.92 GFF3003 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) low > 78
Klebsiella michiganensis M5al 0.86 BWI76_RS18090 phosphoribosylglycinamide formyltransferase 2 0.89 BWI76_RS23870 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) low > 92
Enterobacter sp. TBS_079 0.84 MPMX20_02754 Formate-dependent phosphoribosylglycinamide formyltransferase 0.89 MPMX20_03762 Glycine dehydrogenase (decarboxylating) low > 85
Enterobacter asburiae PDN3 0.83 EX28DRAFT_0707 formate-dependent phosphoribosylglycinamide formyltransferase (EC 6.3.4.-) 0.88 EX28DRAFT_2955 glycine dehydrogenase (decarboxylating) low > 76
Erwinia tracheiphila SCR3 0.82 LU632_RS13350 purT formate-dependent phosphoribosylglycinamide formyltransferase 0.81 LU632_RS05915 gcvP aminomethyl-transferring glycine dehydrogenase low > 74
Pantoea sp. MT58 0.80 IAI47_08505 formate-dependent phosphoribosylglycinamide formyltransferase 0.82 IAI47_03775 aminomethyl-transferring glycine dehydrogenase low > 76
Dickeya dianthicola ME23 0.78 DZA65_RS10590 formate-dependent phosphoribosylglycinamide formyltransferase 0.80 DZA65_RS03445 aminomethyl-transferring glycine dehydrogenase low > 75
Dickeya dadantii 3937 0.78 DDA3937_RS10145 formate-dependent phosphoribosylglycinamide formyltransferase 0.80 DDA3937_RS03255 aminomethyl-transferring glycine dehydrogenase low > 74
Serratia liquefaciens MT49 0.77 IAI46_14770 formate-dependent phosphoribosylglycinamide formyltransferase 0.82 IAI46_20850 aminomethyl-transferring glycine dehydrogenase low > 86
Dickeya dianthicola 67-19 0.77 HGI48_RS10175 formate-dependent phosphoribosylglycinamide formyltransferase 0.80 HGI48_RS03400 aminomethyl-transferring glycine dehydrogenase low > 71
Pectobacterium carotovorum WPP14 0.77 HER17_RS11770 formate-dependent phosphoribosylglycinamide formyltransferase 0.80 HER17_RS17995 aminomethyl-transferring glycine dehydrogenase low > 75
Rahnella sp. WP5 0.77 EX31_RS24735 formate-dependent phosphoribosylglycinamide formyltransferase 0.81 EX31_RS21520 aminomethyl-transferring glycine dehydrogenase low > 89
Vibrio cholerae E7946 ATCC 55056 0.71 CSW01_06215 phosphoribosylglycinamide formyltransferase 2 0.58 CSW01_15330 glycine dehydrogenase (decarboxylating) low > 62
Shewanella sp. ANA-3 0.69 Shewana3_3197 purT phosphoribosylglycinamide formyltransferase 2 (RefSeq) 0.67 Shewana3_3499 glycine dehydrogenase (RefSeq) low > 73
Shewanella amazonensis SB2B 0.68 Sama_2807 purT phosphoribosylglycinamide formyltransferase 2 (RefSeq) 0.68 Sama_2719 glycine dehydrogenase (RefSeq) low > 62
Pseudomonas putida KT2440 0.68 PP_1457 Phosphoribosylglycinamide formyltransferase 2 0.61 PP_5192 glycine dehydrogenase low > 96
Shewanella oneidensis MR-1 0.68 SO3613 purT phosphoribosylglycinamide formyltransferase 2 (NCBI ptt file) 0.67 SO0781 gcvP glycine cleavage system P protein (NCBI ptt file) low > 76
Pseudomonas fluorescens FW300-N2E2 0.68 Pf6N2E2_5444 Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) 0.56 Pf6N2E2_5558 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) low > 103
Pseudomonas fluorescens FW300-N1B4 0.67 Pf1N1B4_879 Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) 0.62 Pf1N1B4_2236 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) low > 87
Pseudomonas fluorescens FW300-N2C3 0.67 AO356_17605 phosphoribosylglycinamide formyltransferase 0.56 AO356_18170 glycine dehydrogenase low > 104
Pseudomonas fluorescens SBW25-INTG 0.67 PFLU_RS24605 formate-dependent phosphoribosylglycinamide formyltransferase 0.56 PFLU_RS24000 aminomethyl-transferring glycine dehydrogenase low > 109
Pseudomonas sp. RS175 0.67 PFR28_03502 Formate-dependent phosphoribosylglycinamide formyltransferase 0.56 PFR28_03383 Glycine dehydrogenase (decarboxylating) low > 88
Pseudomonas fluorescens SBW25 0.67 PFLU_RS24605 formate-dependent phosphoribosylglycinamide formyltransferase 0.56 PFLU_RS24000 aminomethyl-transferring glycine dehydrogenase low > 109
Pseudomonas simiae WCS417 0.67 PS417_22945 phosphoribosylglycinamide formyltransferase 0.56 PS417_22360 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) low > 88
Pseudomonas fluorescens FW300-N2E3 0.67 AO353_04410 phosphoribosylglycinamide formyltransferase 0.62 AO353_08720 glycine dehydrogenase low > 101
Pseudomonas syringae pv. syringae B728a 0.67 Psyr_1277 formate-dependent phosphoribosylglycinamide formyltransferase 0.56 Psyr_1096 glycine dehydrogenase (decarboxylating) alpha subunit / glycine dehydrogenase (decarboxylating) beta subunit low > 86
Pseudomonas syringae pv. syringae B728a ΔmexB 0.67 Psyr_1277 formate-dependent phosphoribosylglycinamide formyltransferase 0.56 Psyr_1096 glycine dehydrogenase (decarboxylating) alpha subunit / glycine dehydrogenase (decarboxylating) beta subunit low > 86
Pseudomonas fluorescens GW456-L13 0.67 PfGW456L13_4820 Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) 0.62 PfGW456L13_904 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) low > 87
Pseudomonas sp. S08-1 0.67 OH686_17700 phosphoribosylglycinamide formyltransferase 2 0.63 OH686_11165 glycine dehydrogenase low > 80
Kangiella aquimarina DSM 16071 0.66 B158DRAFT_2254 formate-dependent phosphoribosylglycinamide formyltransferase (EC 6.3.4.-) 0.58 B158DRAFT_0545 glycine dehydrogenase (decarboxylating) — —
Pseudomonas stutzeri RCH2 0.64 Psest_3137 phosphoribosylglycinamide formyltransferase 2 0.62 Psest_0183 glycine dehydrogenase (decarboxylating) low > 67
Xanthomonas campestris pv. campestris strain 8004 0.63 Xcc-8004.3846.1 Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) 0.54 Xcc-8004.3878.1 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) low > 74
Rhodanobacter denitrificans MT42 0.63 LRK55_RS14260 formate-dependent phosphoribosylglycinamide formyltransferase 0.56 LRK55_RS00260 aminomethyl-transferring glycine dehydrogenase low > 63
Rhodanobacter sp. FW510-T8 0.63 OKGIIK_03390 purT formate-dependent phosphoribosylglycinamide formyltransferase 0.55 OKGIIK_06740 gcvP2 Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain low > 52
Rhodanobacter denitrificans FW104-10B01 0.63 LRK54_RS14545 formate-dependent phosphoribosylglycinamide formyltransferase 0.56 LRK54_RS00520 aminomethyl-transferring glycine dehydrogenase 0.39 1
Lysobacter sp. OAE881 0.62 ABIE51_RS14525 formate-dependent phosphoribosylglycinamide formyltransferase 0.55 ABIE51_RS14345 aminomethyl-transferring glycine dehydrogenase low > 62
Parabacteroides merdae CL09T00C40 0.61 HMPREF1078_RS10980 formate-dependent phosphoribosylglycinamide formyltransferase 0.47 HMPREF1078_RS15115 aminomethyl-transferring glycine dehydrogenase low > 61
Paraburkholderia sabiae LMG 24235 0.59 QEN71_RS24510 formate-dependent phosphoribosylglycinamide formyltransferase 0.55 QEN71_RS29215 aminomethyl-transferring glycine dehydrogenase low > 153
Dechlorosoma suillum PS 0.59 Dsui_1003 phosphoribosylglycinamide formyltransferase 2 0.61 Dsui_2737 glycine dehydrogenase, decarboxylating low > 51
Paraburkholderia bryophila 376MFSha3.1 0.58 H281DRAFT_00303 formate-dependent phosphoribosylglycinamide formyltransferase 0.56 H281DRAFT_02409 glycine dehydrogenase low > 103
Paraburkholderia graminis OAS925 0.58 ABIE53_001433 phosphoribosylglycinamide formyltransferase 2 0.56 ABIE53_000238 glycine dehydrogenase low > 113
Burkholderia phytofirmans PsJN 0.58 BPHYT_RS06125 phosphoribosylglycinamide formyltransferase 0.56 BPHYT_RS19330 glycine cleavage system P protein (EC 1.4.4.2) (from data) low > 109
Variovorax sp. SCN45 0.54 GFF3604 Formate-dependent phosphoribosylglycinamide formyltransferase 0.54 GFF6478 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) low > 127
Acidovorax sp. GW101-3H11 0.54 Ac3H11_4666 Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) 0.52 Ac3H11_167 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) low > 79
Hydrogenophaga sp. GW460-11-11-14-LB1 0.53 GFF363 Phosphoribosylglycinamide formyltransferase 2 (EC 2.1.2.-) 0.52 GFF5215 Glycine dehydrogenase [decarboxylating] (glycine cleavage system P protein) (EC 1.4.4.2) low > 90
Variovorax sp. OAS795 0.52 ABID97_RS00805 formate-dependent phosphoribosylglycinamide formyltransferase 0.54 ABID97_RS19655 aminomethyl-transferring glycine dehydrogenase low > 91
Cupriavidus basilensis FW507-4G11 0.52 RR42_RS22745 phosphoribosylglycinamide formyltransferase 0.55 RR42_RS20070 glycine dehydrogenase low > 128
Synechococcus elongatus PCC 7942 0.48 Synpcc7942_0588 purT phosphoribosylglycinamide formyltransferase 2 0.53 Synpcc7942_2047 gcvP glycine dehydrogenase low > 38
Bacteroides thetaiotaomicron VPI-5482 0.46 BT0704 phosphoribosylglycinamide formyltransferase 2 (NCBI ptt file) 0.47 BT1147 glycine dehydrogenase [decarboxylating] (NCBI ptt file) low > 81
Bacteroides stercoris CC31F 0.46 HMPREF1181_RS16250 formate-dependent phosphoribosylglycinamide formyltransferase 0.47 HMPREF1181_RS16815 aminomethyl-transferring glycine dehydrogenase low > 56
Bacteroides ovatus ATCC 8483 0.45 BACOVA_02411 phosphoribosylglycinamide formyltransferase 2 0.48 BACOVA_04038 glycine dehydrogenase low > 94
Phocaeicola dorei CL03T12C01 0.44 ABI39_RS14185 formate-dependent phosphoribosylglycinamide formyltransferase 0.46 ABI39_RS15100 aminomethyl-transferring glycine dehydrogenase low > 72
Phocaeicola vulgatus CL09T03C04 0.44 HMPREF1058_RS17920 formate-dependent phosphoribosylglycinamide formyltransferase 0.46 HMPREF1058_RS18780 aminomethyl-transferring glycine dehydrogenase low > 67
Mycobacterium tuberculosis H37Rv 0.31 Rv0389 Probable phosphoribosylglycinamide formyltransferase 2 PurT (GART 2) (gar transformylase 2) (5'-phosphoribosylglycinamide transformylase 2) (formate-dependent gar transformylase) 0.50 Rv1832 Probable glycine dehydrogenase GcvB (glycine decarboxylase) (glycine cleavage system P-protein) — —

Not shown: 12 genomes with orthologs for b1849 only; 20 genomes with orthologs for b2903 only