| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Enterobacter sp. TBS_079 | MPMX20_00642 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | insig. | 100 | 100 |
| o | Enterobacter asburiae PDN3 | EX28DRAFT_3547 | | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit/4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit | insig. | 89 | 100 |
| o | Escherichia coli ECOR27 | NOLOHH_03715 | hpaG | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 84 | 100 |
| o | Escherichia coli ECRC62 | BNILDI_07885 | hpaG | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 84 | 100 |
| o | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03710 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | cofit | 84 | 100 |
| o | Escherichia coli BL21 | ECD_04230 | | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 84 | 100 |
| o | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3278 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 84 | 100 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_12120 | | 2-hydroxyhepta-2 4-diene-1 7-dioate isomerase | insig. | 87 | 49 |
| | Klebsiella michiganensis M5al | BWI76_RS03870 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 86 | 49 |
| | Klebsiella pneumoniae MKP103 | KDGMDA_12125 | | 2-hydroxyhepta-2 4-diene-1 7-dioate isomerase | insig. | 80 | 49 |
| | Klebsiella michiganensis M5al | BWI76_RS03875 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | sig. | 80 | 49 |
| | Serratia liquefaciens MT49 | IAI46_02730 | | fumarylacetoacetate hydrolase family protein | insig. | 76 | 49 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS15925 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 73 | 49 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS15925 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | strong | 73 | 49 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS13530 | | fumarylacetoacetate hydrolase family protein | insig. | 60 | 58 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1308 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 72 | 49 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02387 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | cofit | 74 | 48 |
| | Pseudomonas sp. SVBP6 | COO64_RS13790 | | fumarylacetoacetate hydrolase family protein | insig. | 72 | 49 |
| | Pseudomonas simiae WCS417 | PS417_17835 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | sig. | 72 | 49 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_25590 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 72 | 49 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_21230 | | 2-hydroxyhepta-2 4-diene-1 7-dioate isomerase | insig. | 72 | 48 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS27830 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 66 | 47 |
| | Serratia liquefaciens MT49 | IAI46_02725 | | fumarylacetoacetate hydrolase family protein | insig. | 64 | 49 |
| | Azospirillum sp. SherDot2 | MPMX19_06799 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | insig. | 62 | 47 |
| | Castellaniella sp019104865 MT123 | ABCV34_RS09310 | | fumarylacetoacetate hydrolase family protein | insig. | 54 | 58 |
| | Variovorax sp. OAS795 | ABID97_RS03755 | | fumarylacetoacetate hydrolase family protein | sig. | 60 | 47 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS04120 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | cofit | 58 | 48 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1828 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 59 | 47 |
| | Variovorax sp. SCN45 | GFF7103 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 59 | 47 |
| | Paraburkholderia graminis OAS925 | ABIE53_005228 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | sig. | 56 | 54 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS34380 | | fumarylacetoacetate hydrolase family protein | insig. | 54 | 58 |
| | Variovorax sp. SCN45 | GFF5092 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 59 | 47 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03257 | | 5-carboxy-2-oxohept-3-enedioate decarboxylase HpaG2 subunit | no data | 61 | 48 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS12030 | | fumarylacetoacetate hydrolase family protein | insig. | 53 | 58 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS28880 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 53 | 58 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_1487 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 57 | 49 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02388 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | cofit | 46 | 48 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1307 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 45 | 48 |
| | Pseudomonas sp. SVBP6 | COO64_RS13795 | | fumarylacetoacetate hydrolase family protein | insig. | 44 | 49 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS15920 | | 4-hydroxyphenylacetate isomerase | insig. | 45 | 48 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS15920 | | 4-hydroxyphenylacetate isomerase | strong | 45 | 48 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_25595 | | 4-hydroxyphenylacetate isomerase | insig. | 45 | 48 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_21225 | | 4-hydroxyphenylacetate isomerase | insig. | 45 | 48 |
| | Pseudomonas simiae WCS417 | PS417_17830 | | 4-hydroxyphenylacetate isomerase | insig. | 45 | 48 |
| | Rhizobium sp. OAE497 | ABIE40_RS19310 | | fumarylacetoacetate hydrolase family protein | strong | 42 | 47 |
| | Pseudomonas sp. SVBP6 | COO64_RS13795 | | fumarylacetoacetate hydrolase family protein | insig. | 45 | 48 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_25595 | | 4-hydroxyphenylacetate isomerase | insig. | 45 | 48 |
| | Rhodopseudomonas palustris CGA009 | TX73_022935 | | fumarylacetoacetate hydrolase family protein | insig. | 43 | 47 |
| | Variovorax sp. OAS795 | ABID97_RS28035 | | fumarylacetoacetate hydrolase family protein | insig. | 41 | 52 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1307 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 45 | 48 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS08350 | | ureidoglycolate lyase | insig. | 38 | 56 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02388 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | cofit | 45 | 48 |
| | Azospirillum sp. SherDot2 | MPMX19_03313 | | Ureidoglycolate lyase | insig. | 38 | 48 |
| | Pseudomonas simiae WCS417 | PS417_17830 | | 4-hydroxyphenylacetate isomerase | insig. | 43 | 48 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_21225 | | 4-hydroxyphenylacetate isomerase | insig. | 42 | 48 |
| | Sinorhizobium meliloti 1021 | SM_b21112 | | L-2,4-diketo-3-deoxyrhamnonate hydrolase; 2,4-dioxopentanoate hydrolase (from data) | strong | 40 | 47 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_2925 | | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase (RefSeq) | insig. | 41 | 48 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS15920 | | 4-hydroxyphenylacetate isomerase | insig. | 43 | 48 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS15920 | | 4-hydroxyphenylacetate isomerase | strong | 43 | 48 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_02528 | | 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) | insig. | 41 | 47 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2939 | | 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) | insig. | 39 | 46 |
| | Xanthobacter sp. DMC5 | GFF3364 | | Ureidoglycolate lyase | insig. | 38 | 48 |
| | Rhizobium sp. OAE497 | ABIE40_RS19950 | | fumarylacetoacetate hydrolase family protein | insig. | 39 | 46 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS07600 | | fumarylacetoacetate hydrolase family protein | strong | 39 | 55 |
| | Agrobacterium fabrum C58 | Atu0014 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | strong | 39 | 47 |
| | Rhizobium sp. OAE497 | ABIE40_RS21630 | | fumarylacetoacetate hydrolase family protein | insig. | 39 | 45 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0875 | | fumarylacetoacetate hydrolase family protein (TIGR) | insig. | 42 | 47 |
| | Variovorax sp. SCN45 | GFF3754 | | Fumarylacetoacetate hydrolase family protein | insig. | 38 | 49 |
| | Rhodospirillum rubrum S1H | Rru_A2126 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase (NCBI) | insig. | 40 | 47 |
| | Pseudomonas fluorescens FW300-N2E3 | AO353_24305 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 39 | 47 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c04530 | | ureidoglycolate lyase | insig. | 39 | 48 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS00385 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 38 | 48 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS24410 | | 5-carboxymethyl-2-hydroxymuconate isomerase | insig. | 41 | 49 |
| | Azospirillum sp. SherDot2 | MPMX19_06074 | | Ureidoglycolate lyase | insig. | 39 | 46 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.5166.1 | | hypothetical protein | insig. | 40 | 46 |
| | Xanthobacter sp. DMC5 | GFF994 | | Ureidoglycolate lyase | insig. | 39 | 47 |
| | Mycobacterium tuberculosis H37Rv | Rv2993c | | Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase) | sig. | 36 | 53 |
| | Bosea sp. OAE506 | ABIE41_RS22825 | | fumarylacetoacetate hydrolase family protein | insig. | 38 | 54 |
| | Variovorax sp. OAS795 | ABID97_RS05835 | | fumarylacetoacetate hydrolase family protein | strong | 35 | 59 |
| | Azospirillum brasilense Sp245 | AZOBR_RS15905 | | 2-hydroxyhepta-2 4-diene-1 7-dioate isomerase | insig. | 38 | 46 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS07330 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase | insig. | 39 | 50 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS19960 | | fumarylacetoacetate hydrolase family protein | insig. | 39 | 46 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS12025 | | fumarylacetoacetate hydrolase family protein | insig. | 41 | 45 |
| | Methanococcus maripaludis S2 | MMP_RS00825 | | fumarylacetoacetate hydrolase family protein | insig. | 38 | 47 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS01325 | | fumarylacetoacetate hydrolase family protein | insig. | 38 | 46 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS05150 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase | insig. | 39 | 49 |
| | Dinoroseobacter shibae DFL-12 | Dshi_2542 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase (RefSeq) | insig. | 40 | 48 |
| | Variovorax sp. OAS795 | ABID97_RS26355 | | fumarylacetoacetate hydrolase family protein | insig. | 36 | 49 |
| | Enterobacter sp. TBS_079 | MPMX20_02705 | | putative protein YcgM | insig. | 41 | 46 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2290 | | Fumarylacetoacetate hydrolase family protein | insig. | 40 | 48 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS27825 | | 4-hydroxyphenylacetate isomerase | insig. | 39 | 45 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS21875 | | FAA hydrolase family protein | insig. | 37 | 48 |
| | Cellulophaga baltica 18 | M666_RS00130 | | fumarylacetoacetate hydrolase family protein | insig. | 40 | 46 |
| | Sphingobium sp. HT1-2 | GFF2856 | | 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) | cofit | 39 | 49 |
| | Azospirillum brasilense Sp245 | AZOBR_RS26375 | | hypothetical protein | insig. | 38 | 52 |
| | Methanococcus maripaludis JJ | MMJJ_RS04665 | | fumarylacetoacetate hydrolase family protein | insig. | 38 | 47 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_28735 | | ureidoglycolate lyase | no data | 40 | 46 |
| | Variovorax sp. SCN45 | GFF4615 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase | insig. | 35 | 54 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS20835 | | ureidoglycolate lyase | insig. | 38 | 48 |
| | Serratia liquefaciens MT49 | IAI46_12460 | | fumarylacetoacetate hydrolase family protein | insig. | 37 | 49 |