| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Azospirillum sp. SherDot2 | MPMX19_06799 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | insig. | 100 | 100 |
| o | Ralstonia sp. UNC404CL21Col | ABZR87_RS13530 | | fumarylacetoacetate hydrolase family protein | insig. | 74 | 100 |
| o | Cupriavidus basilensis FW507-4G11 | RR42_RS27830 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 71 | 100 |
| o | Variovorax sp. SCN45 | GFF7103 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 67 | 99 |
| o | Castellaniella sp019104865 MT123 | ABCV34_RS09310 | | fumarylacetoacetate hydrolase family protein | insig. | 70 | 100 |
| o | Magnetospirillum magneticum AMB-1 | AMB_RS04120 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | cofit | 69 | 99 |
| o | Variovorax sp. OAS795 | ABID97_RS03755 | | fumarylacetoacetate hydrolase family protein | sig. | 65 | 99 |
| | Variovorax sp. SCN45 | GFF5092 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 65 | 99 |
| o | Pseudomonas orientalis W4I3 | QF045_RS12930 | | fumarylacetoacetate hydrolase family protein | insig. | 64 | 100 |
| o | Paraburkholderia graminis OAS925 | ABIE53_005228 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase/2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | sig. | 64 | 100 |
| o | Pseudomonas fluorescens SBW25 | PFLU_RS15925 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 64 | 100 |
| o | Pseudomonas fluorescens SBW25-INTG | PFLU_RS15925 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | strong | 64 | 100 |
| o | Burkholderia phytofirmans PsJN | BPHYT_RS28880 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 65 | 99 |
| o | Paraburkholderia sabiae LMG 24235 | QEN71_RS34380 | | fumarylacetoacetate hydrolase family protein | insig. | 63 | 100 |
| o | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03257 | | 5-carboxy-2-oxohept-3-enedioate decarboxylase HpaG2 subunit | no data | 63 | 100 |
| o | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF1828 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 65 | 99 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_1487 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 63 | 100 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS12030 | | fumarylacetoacetate hydrolase family protein | insig. | 62 | 100 |
| o | Serratia liquefaciens MT49 | IAI46_02730 | | fumarylacetoacetate hydrolase family protein | insig. | 62 | 100 |
| o | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1308 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 65 | 100 |
| o | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02387 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | cofit | 65 | 100 |
| o | Klebsiella pneumoniae MKP103 | KDGMDA_12120 | | 2-hydroxyhepta-2 4-diene-1 7-dioate isomerase | insig. | 59 | 100 |
| o | Klebsiella michiganensis M5al | BWI76_RS03870 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 59 | 100 |
| o | Pseudomonas fluorescens FW300-N2C3 | AO356_25590 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 64 | 100 |
| o | Pseudomonas simiae WCS417 | PS417_17835 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | sig. | 64 | 100 |
| o | Pseudomonas sp. SVBP6 | COO64_RS13790 | | fumarylacetoacetate hydrolase family protein | insig. | 63 | 100 |
| o | Pseudomonas aeruginosa PUPa3 | DQ20_RS47550 | | fumarylacetoacetate hydrolase family protein | insig. | 63 | 100 |
| o | Pseudomonas aeruginosa PA14 | IKLFDK_21230 | | 2-hydroxyhepta-2 4-diene-1 7-dioate isomerase | insig. | 62 | 100 |
| o | Pseudomonas aeruginosa MRSN321 | DY961_RS28090 | | fumarylacetoacetate hydrolase family protein | insig. | 62 | 100 |
| | Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 | GFF3278 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 65 | 82 |
| | Enterobacter sp. TBS_079 | MPMX20_00642 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | insig. | 62 | 82 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_3547 | | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, C-terminal subunit/4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase, N-terminal subunit | insig. | 64 | 82 |
| | Escherichia coli HS(pFamp)R (ATCC 700891) | OHPLBJKB_03710 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | cofit | 62 | 84 |
| | Escherichia coli ECOR27 | NOLOHH_03715 | hpaG | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 62 | 84 |
| | Escherichia coli BL21 | ECD_04230 | | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 62 | 84 |
| | Escherichia coli ECRC62 | BNILDI_07885 | hpaG | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase | insig. | 62 | 84 |
| | Mycobacterium tuberculosis H37Rv | Rv2993c | | Possible 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (HHDD isomerase) | sig. | 41 | 90 |
| o | Desulfovibrio vulgaris Miyazaki F | DvMF_2925 | | 5-carboxymethyl-2-hydroxymuconate Delta-isomerase (RefSeq) | insig. | 39 | 99 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS07600 | | fumarylacetoacetate hydrolase family protein | strong | 43 | 85 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS07330 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase | insig. | 40 | 84 |
| | Pseudomonas orientalis W4I3 | QF045_RS12935 | | fumarylacetoacetate hydrolase family protein | insig. | 41 | 82 |
| | Variovorax sp. OAS795 | ABID97_RS28035 | | fumarylacetoacetate hydrolase family protein | insig. | 40 | 100 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2169 | | Putative fumarylacetoacetate (FAA) hydrolase | insig. | 40 | 91 |
| | Pseudomonas sp. SVBP6 | COO64_RS13795 | | fumarylacetoacetate hydrolase family protein | insig. | 43 | 82 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2985 | | Fumarylacetoacetate hydrolase family protein | insig. | 40 | 87 |
| | Serratia liquefaciens MT49 | IAI46_12460 | | fumarylacetoacetate hydrolase family protein | insig. | 40 | 85 |
| | Dinoroseobacter shibae DFL-12 | Dshi_2542 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase (RefSeq) | insig. | 40 | 81 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU0875 | | fumarylacetoacetate hydrolase family protein (TIGR) | insig. | 39 | 99 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_4136 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase. | insig. | 41 | 82 |
| | Methanococcus maripaludis S2 | MMP_RS00825 | | fumarylacetoacetate hydrolase family protein | insig. | 38 | 83 |
| | Ralstonia solanacearum PSI07 | RPSI07_RS21875 | | FAA hydrolase family protein | insig. | 42 | 81 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02388 | | Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase | cofit | 39 | 82 |
| | Variovorax sp. SCN45 | GFF1055 | | Fumarylacetoacetate hydrolase family protein | insig. | 41 | 85 |
| | Xanthomonas campestris pv. campestris strain 8004 | Xcc-8004.5166.1 | | hypothetical protein | insig. | 40 | 81 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS15575 | | fumarylacetoacetate hydrolase family protein | insig. | 43 | 81 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS15575 | | fumarylacetoacetate hydrolase family protein | insig. | 43 | 81 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_25595 | | 4-hydroxyphenylacetate isomerase | insig. | 40 | 82 |
| | Xanthobacter sp. DMC5 | GFF3364 | | Ureidoglycolate lyase | insig. | 39 | 93 |
| | Pseudomonas aeruginosa MRSN321 | DY961_RS28085 | | fumarylacetoacetate hydrolase family protein | insig. | 41 | 82 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_4807 | | 5-carboxymethyl-2-hydroxymuconate delta-isomerase( EC:5.3.3.10 ) | insig. | 38 | 100 |
| | Klebsiella michiganensis M5al | BWI76_RS05690 | | fumarylacetoacetate (FAA) hydrolase | insig. | 37 | 86 |
| | Pseudomonas sp. BP01 | JOY50_RS12450 | | fumarylacetoacetate hydrolase family protein | insig. | 37 | 90 |
| | Rahnella sp. WP5 | EX31_RS00035 | | fumarylacetoacetate hydrolase family protein | insig. | 35 | 93 |
| | Methanococcus maripaludis JJ | MMJJ_RS04665 | | fumarylacetoacetate hydrolase family protein | insig. | 38 | 83 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS01325 | | fumarylacetoacetate hydrolase family protein | insig. | 39 | 92 |
| | Rhodopseudomonas palustris CGA009 | TX73_022935 | | fumarylacetoacetate hydrolase family protein | insig. | 40 | 81 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS24410 | | 5-carboxymethyl-2-hydroxymuconate isomerase | insig. | 39 | 85 |
| | Azospirillum sp. SherDot2 | MPMX19_03313 | | Ureidoglycolate lyase | insig. | 38 | 92 |
| | Enterobacter sp. TBS_079 | MPMX20_03828 | | hypothetical protein | insig. | 37 | 90 |
| | Pseudomonas simiae WCS417 | PS417_17830 | | 4-hydroxyphenylacetate isomerase | insig. | 42 | 82 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_2939 | | 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) | insig. | 38 | 81 |
| | Enterobacter asburiae PDN3 | EX28DRAFT_3008 | | 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) | insig. | 37 | 90 |
| | Pseudomonas aeruginosa PA14 | IKLFDK_21225 | | 4-hydroxyphenylacetate isomerase | sig. | 40 | 82 |
| | Pseudomonas aeruginosa PUPa3 | DQ20_RS47555 | | fumarylacetoacetate hydrolase family protein | insig. | 40 | 82 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_1307 | | 5-carboxymethyl-2-oxo-hex-3- ene-1,7-dioate decarboxylase (EC 4.1.1.68) / 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase (EC 5.3.3.-) | insig. | 40 | 82 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2290 | | Fumarylacetoacetate hydrolase family protein | insig. | 39 | 96 |
| | Variovorax sp. OAS795 | ABID97_RS26355 | | fumarylacetoacetate hydrolase family protein | insig. | 39 | 84 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS05150 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase | insig. | 39 | 83 |
| | Cupriavidus basilensis FW507-4G11 | RR42_RS00385 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | insig. | 42 | 81 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2298 | | Putative fumarylacetoacetate (FAA) hydrolase | insig. | 40 | 86 |
| | Rhizobium sp. OAE497 | ABIE40_RS19310 | | fumarylacetoacetate hydrolase family protein | strong | 38 | 81 |
| | Rhodospirillum rubrum S1H | Rru_A2126 | | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase (NCBI) | insig. | 39 | 82 |
| | Variovorax sp. SCN45 | GFF3754 | | Fumarylacetoacetate hydrolase family protein | insig. | 37 | 97 |
| | Variovorax sp. OAS795 | ABID97_RS05835 | | fumarylacetoacetate hydrolase family protein | strong | 37 | 97 |
| | Phaeobacter inhibens DSM 17395 | PGA1_c04530 | | ureidoglycolate lyase | insig. | 41 | 80 |
| | Bosea sp. OAE506 | ABIE41_RS20235 | | fumarylacetoacetate hydrolase family protein | insig. | 40 | 85 |
| | Agrobacterium fabrum C58 | Atu0014 | | 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase | strong | 37 | 81 |
| | Azospirillum brasilense Sp245 | AZOBR_RS15905 | | 2-hydroxyhepta-2 4-diene-1 7-dioate isomerase | insig. | 38 | 81 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_229 | | Putative fumarylacetoacetate (FAA) hydrolase | insig. | 39 | 85 |
| | Sphingomonas koreensis DSMZ 15582 | Ga0059261_2636 | | 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) | insig. | 40 | 82 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_00660 | | 5-carboxymethyl-2-hydroxymuconate isomerase | insig. | 39 | 85 |
| | Xanthobacter sp. DMC5 | GFF2142 | | Ureidoglycolate lyase | insig. | 34 | 94 |
| | Azospirillum brasilense Sp245 | AZOBR_RS26375 | | hypothetical protein | insig. | 39 | 89 |
| | Bosea sp. OAE506 | ABIE41_RS22825 | | fumarylacetoacetate hydrolase family protein | insig. | 40 | 83 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS20080 | | fumarylacetoacetate hydrolase family protein | insig. | 39 | 85 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS20080 | | fumarylacetoacetate hydrolase family protein | sig. | 39 | 85 |
| | Pseudomonas simiae WCS417 | PS417_18185 | | 5-carboxymethyl-2-hydroxymuconate isomerase | insig. | 39 | 85 |
| | Rahnella sp. WP5 | EX31_RS17780 | | fumarylacetoacetate hydrolase family protein | insig. | 36 | 85 |
| | Enterobacter sp. TBS_079 | MPMX20_03497 | | hypothetical protein | no data | 35 | 86 |
| | Xanthobacter sp. DMC5 | GFF3305 | | Ureidoglycolate lyase | insig. | 38 | 86 |