| Orth | Species | Gene | Name | Description | Fitness | %Id | Cov |
| | Azospirillum sp. SherDot2 | MPMX19_04108 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 100 | 100 |
| | Rhizobium sp. OAE497 | ABIE40_RS14675 | | response regulator transcription factor | insig. | 57 | 98 |
| | Azospirillum sp. SherDot2 | MPMX19_04589 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 56 | 94 |
| o | Sinorhizobium meliloti 1021 | SM_b20610 | | two-component response regulator protein | insig. | 56 | 98 |
| | Agrobacterium fabrum C58 | Atu2419 | | transcriptional regulator, LuxR family | insig. | 55 | 98 |
| | Rhodopseudomonas palustris CGA009 | TX73_006410 | | response regulator transcription factor | insig. | 54 | 95 |
| o | Marinobacter adhaerens HP15 | HP15_3660 | | two-component response regulator | insig. | 54 | 93 |
| | Variovorax sp. SCN45 | GFF638 | | Two-component transcriptional response regulator, LuxR family | insig. | 50 | 95 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS13200 | | transcriptional regulator | insig. | 47 | 96 |
| | Methylophilus sp. DMC18 | GFF1954 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | cofit | 43 | 95 |
| o | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF3270 | | Two-component response regulator | insig. | 49 | 96 |
| | Ralstonia sp. UNC404CL21Col | ABZR87_RS22750 | | response regulator transcription factor | insig. | 47 | 93 |
| | Variovorax sp. SCN45 | GFF2488 | | Two-component transcriptional response regulator, LuxR family | insig. | 44 | 97 |
| o | Variovorax sp. OAS795 | ABID97_RS23505 | | response regulator transcription factor | insig. | 41 | 97 |
| | Hydrogenophaga sp. GW460-11-11-14-LB1 | GFF2878 | | Two-component response regulator | insig. | 44 | 98 |
| o | Acidovorax sp. GW101-3H11 | Ac3H11_3695 | | Two-component response regulator | sig. | 46 | 94 |
| | Pseudomonas fluorescens SBW25 | PFLU_RS12370 | | response regulator transcription factor | insig. | 59 | 43 |
| | Pseudomonas fluorescens SBW25-INTG | PFLU_RS12370 | | response regulator transcription factor | insig. | 59 | 43 |
| | Pseudomonas simiae WCS417 | PS417_11585 | | LuxR family transcriptional regulator | insig. | 59 | 43 |
| | Pseudomonas fluorescens FW300-N2E2 | Pf6N2E2_181 | | Two-component response regulator | insig. | 57 | 43 |
| | Pseudomonas sp. S08-1 | OH686_16560 | | Two-component transcriptional response regulator, LuxR family | insig. | 58 | 42 |
| | Pseudomonas segetis P6 | ACVTMO_RS02300 | | response regulator | insig. | 55 | 43 |
| | Paraburkholderia sabiae LMG 24235 | QEN71_RS32075 | | response regulator | insig. | 57 | 38 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS30905 | | histidine kinase | insig. | 54 | 39 |
| | Paraburkholderia bryophila 376MFSha3.1 | H281DRAFT_03106 | | PAS domain S-box-containing protein | insig. | 50 | 38 |
| | Paraburkholderia graminis OAS925 | ABIE53_004192 | | PAS domain S-box-containing protein | strong | 50 | 38 |
| | Shewanella sp. ANA-3 | Shewana3_3418 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 52 | 38 |
| | Burkholderia phytofirmans PsJN | BPHYT_RS11870 | | AraC family transcriptional regulator | insig. | 49 | 40 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS03320 | | EAL domain-containing protein | insig. | 42 | 38 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS09310 | | two-component system response regulator | insig. | 50 | 39 |
| | Shewanella amazonensis SB2B | Sama_2951 | | response regulator receiver protein (RefSeq) | insig. | 49 | 38 |
| | Azospirillum sp. SherDot2 | MPMX19_02025 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 47 | 41 |
| | Shewanella loihica PV-4 | Shew_3199 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 46 | 39 |
| | Shewanella oneidensis MR-1 | SO0860 | | response regulator (NCBI ptt file) | insig. | 48 | 40 |
| | Paraburkholderia graminis OAS925 | ABIE53_004362 | | DNA-binding response OmpR family regulator | insig. | 48 | 40 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS08635 | | response regulator | sig. | 36 | 54 |
| | Alteromonas macleodii MIT1002 | MIT1002_00763 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 47 | 41 |
| | Dyella japonica UNC79MFTsu3.2 | ABZR86_RS03625 | | response regulator | insig. | 41 | 53 |
| | Pseudomonas sp. S08-1 | OH686_00410 | | Response regulator c-di-GMP phosphodiesterase, RpfG family | insig. | 43 | 47 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_06795 | | two-component system response regulator | insig. | 43 | 40 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS18655 | | response regulator | insig. | 48 | 40 |
| | Desulfovibrio vulgaris Miyazaki F | DvMF_1097 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 44 | 46 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2270 | | Pole remodelling regulatory diguanylate cyclase | insig. | 46 | 40 |
| | Marinobacter adhaerens HP15 | HP15_1054 | | multi-sensor signal transduction histidine kinase | strong | 39 | 40 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_4352 | | Response regulator | insig. | 45 | 41 |
| | Alteromonas macleodii MIT1002 | MIT1002_01768 | | Cyclic di-GMP phosphodiesterase response regulator RpfG | insig. | 46 | 39 |
| | Azospirillum brasilense Sp245 | AZOBR_RS03050 | | diguanylate cyclase | sig. | 46 | 41 |
| | Dechlorosoma suillum PS | Dsui_0777 | | response regulator containing a CheY-like receiver domain and an HD-GYP domain | cofit | 47 | 40 |
| | Azospirillum brasilense Sp245 | AZOBR_RS14285 | | transcriptional regulator | strong | 42 | 47 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS09200 | | two-component system response regulator | cofit | 47 | 39 |
| | Shewanella amazonensis SB2B | Sama_3594 | | response regulator receiver protein (RefSeq) | insig. | 40 | 46 |
| | Sphingobium sp. HT1-2 | GFF2748 | | Pole remodelling regulatory diguanylate cyclase | cofit | 43 | 40 |
| | Azospirillum sp. SherDot2 | MPMX19_01522 | | Response regulator PleD | insig. | 42 | 37 |
| | Pseudomonas segetis P6 | ACVTMO_RS19850 | | HD domain-containing phosphohydrolase | insig. | 46 | 39 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS11200 | | hybrid sensor histidine kinase/response regulator transcription factor | insig. | 42 | 39 |
| | Azospirillum sp. SherDot2 | MPMX19_06045 | | putative cyclic di-GMP phosphodiesterase | insig. | 44 | 38 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS09305 | | two-component system response regulator | insig. | 43 | 39 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS03035 | | diguanylate cyclase | sig. | 39 | 41 |
| | Shewanella sp. ANA-3 | Shewana3_0479 | | response regulator receiver modulated metal dependent phosphohydrolase (RefSeq) | insig. | 46 | 39 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT4137 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 40 | 43 |
| | Azospirillum brasilense Sp245 | AZOBR_RS16180 | | diguanylate cyclase | strong | 42 | 37 |
| | Agrobacterium fabrum C58 | Atu1297 | | two component response regulator | insig. | 42 | 37 |
| | Magnetospirillum magneticum AMB-1 | AMB_RS20960 | | two-component system response regulator | cofit | 46 | 39 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_2310 | | Pole remodelling regulatory diguanylate cyclase | insig. | 43 | 40 |
| | Rhodopseudomonas palustris CGA009 | TX73_016195 | | PleD family two-component system response regulator | insig. | 43 | 37 |
| | Synechocystis sp000284455 PCC 6803 | SGL_RS09195 | | hybrid sensor histidine kinase/response regulator | insig. | 42 | 41 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT1635 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 41 | 39 |
| | Pseudomonas sp. S08-1 | OH686_23615 | | Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY | insig. | 46 | 36 |
| | Pseudomonas sp. S08-1 | OH686_23605 | | Response regulator c-di-GMP phosphodiesterase, RpfG family | insig. | 44 | 38 |
| | Mucilaginibacter yixingensis YX-36 DSM 26809 | ABZR88_RS07185 | | two-component regulator propeller domain-containing protein | insig. | 43 | 40 |
| | Shewanella amazonensis SB2B | Sama_0748 | | response regulator receiver protein (RefSeq) | sig. | 40 | 40 |
| | Dechlorosoma suillum PS | Dsui_0331 | | PAS domain S-box | insig. | 37 | 53 |
| | Azospirillum brasilense Sp245 | AZOBR_RS14200 | | chemotaxis protein CheY | strong | 41 | 39 |
| | Vibrio cholerae E7946 ATCC 55056 | CSW01_03275 | | hybrid sensor histidine kinase/response regulator | insig. | 37 | 40 |
| | Pseudomonas stutzeri RCH2 | Psest_1725 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | strong | 44 | 36 |
| | Desulfovibrio vulgaris Hildenborough JW710 | DVU1083 | phoB | phosphate regulon transcriptional regulator PhoB (TIGR) | no data | 39 | 53 |
| | Rhizobium sp. OAE497 | ABIE40_RS07330 | | PleD family two-component system response regulator | cofit | 43 | 37 |
| | Azospirillum brasilense Sp245 | AZOBR_RS22685 | | response regulator PleD (with diguanylate cyclase and response regulator receiver domains) (fragment) | insig. | 48 | 34 |
| | Acidovorax sp. GW101-3H11 | Ac3H11_3644 | | Pole remodelling regulatory diguanylate cyclase | insig. | 44 | 45 |
| | Azospirillum sp. SherDot2 | MPMX19_01958 | | Protein-glutamate methylesterase/protein-glutamine glutaminase | insig. | 42 | 38 |
| | Pedobacter sp. GW460-11-11-14-LB5 | CA265_RS11205 | | hybrid sensor histidine kinase/response regulator | insig. | 41 | 38 |
| | Herbaspirillum seropedicae SmR1 | HSERO_RS06860 | | AraC family transcriptional regulator | sig. | 38 | 43 |
| | Dinoroseobacter shibae DFL-12 | Dshi_2820 | | response regulator receiver modulated diguanylate cyclase (RefSeq) | sig. | 42 | 37 |
| | Bacteroides thetaiotaomicron VPI-5482 | BT3172 | | two-component system sensor histidine kinase/response regulator, hybrid ('one-component system') (NCBI ptt file) | insig. | 38 | 39 |
| | Pseudomonas fluorescens FW300-N2C3 | AO356_29430 | | histidine kinase | insig. | 43 | 41 |
| | Pseudomonas sp. S08-1 | OH686_07455 | | Response regulator c-di-GMP phosphodiesterase, RpfG family | insig. | 41 | 39 |
| | Dinoroseobacter shibae DFL-12 | Dshi_1538 | | two component transcriptional regulator, winged helix family (RefSeq) | no data | 40 | 42 |
| | Acinetobacter radioresistens SK82 | MPMX26_02958 | | Phosphate regulon transcriptional regulatory protein PhoB | strong | 40 | 46 |
| | Bacteroides stercoris CC31F | HMPREF1181_RS15245 | | response regulator | insig. | 38 | 44 |
| | Bacteroides ovatus ATCC 8483 | BACOVA_02648 | | ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein | cofit | 36 | 50 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS08350 | | PleD family two-component system response regulator | insig. | 53 | 29 |
| | Sinorhizobium meliloti 1021 | SMc01370 | | response regulator PleD | insig. | 42 | 39 |
| | Caulobacter crescentus NA1000 | CCNA_02546 | | GGDEF/response regulator protein PleD | strong | 33 | 63 |
| | Caulobacter crescentus NA1000 Δfur | CCNA_02546 | | GGDEF/response regulator protein PleD | cofit | 33 | 63 |
| | Brevundimonas sp. GW460-12-10-14-LB2 | A4249_RS05185 | | response regulator | insig. | 42 | 40 |
| | Echinicola vietnamensis KMM 6221, DSM 17526 | Echvi_0046 | | Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain | sig. | 41 | 37 |
| | Azospirillum sp. SherDot2 | MPMX19_01858 | | Alkaline phosphatase synthesis transcriptional regulatory protein PhoP | insig. | 42 | 38 |
| | Pseudomonas lactucae CFBP13502 | GEMAOFIL_02886 | | Sensor histidine kinase RcsC | insig. | 41 | 41 |
| | Shewanella amazonensis SB2B | Sama_3111 | | response regulator receiver protein (RefSeq) | insig. | 44 | 39 |
| | Synechococcus elongatus PCC 7942 | Synpcc7942_0095 | rpaA | two component transcriptional regulator, winged helix family | strong | 39 | 44 |