Conservation of cofitness between SMc02366 and SM_b20751 in Sinorhizobium meliloti 1021

47 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Sinorhizobium meliloti 1021 1.0 SMc02366 transcriptional regulator 1.0 SM_b20751 3-hydroxyisobutyrate dehydrogenase 0.66 18
Rhizobium sp. OAE497 0.90 ABIE40_RS05700 response regulator transcription factor 0.69 ABIE40_RS24830 3-hydroxyisobutyrate dehydrogenase low > 107
Agrobacterium fabrum C58 0.88 Atu0978 two component response regulator 0.65 Atu4129 3-hydroxyisobutyrate dehydrogenase low > 89
Rhodopseudomonas palustris CGA009 0.73 TX73_009945 response regulator transcription factor 0.60 TX73_017835 3-hydroxyisobutyrate dehydrogenase low > 86
Bosea sp. OAE506 0.72 ABIE41_RS21440 response regulator transcription factor 0.67 ABIE41_RS23930 3-hydroxyisobutyrate dehydrogenase low > 77
Azospirillum sp. SherDot2 0.66 MPMX19_00794 Transcriptional activator protein CopR 0.57 MPMX19_05421 putative 3-hydroxyisobutyrate dehydrogenase low > 112
Azospirillum brasilense Sp245 0.65 AZOBR_RS10800 XRE family transcriptional regulator 0.56 AZOBR_RS22360 3-hydroxyisobutyrate dehydrogenase low > 97
Marinobacter adhaerens HP15 0.64 HP15_3484 DNA-binding response regulator 0.43 HP15_910 3-hydroxyisobutyrate dehydrogenase — —
Magnetospirillum magneticum AMB-1 0.63 AMB_RS14570 DNA-binding response regulator 0.54 AMB_RS18155 3-hydroxyisobutyrate dehydrogenase — —
Caulobacter crescentus NA1000 0.60 CCNA_02845 two-component response regulator 0.46 CCNA_01416 3-hydroxyisobutyrate dehydrogenase low > 66
Caulobacter crescentus NA1000 Δfur 0.60 CCNA_02845 two-component response regulator 0.46 CCNA_01416 3-hydroxyisobutyrate dehydrogenase low > 67
Rhodospirillum rubrum S1H 0.59 Rru_A2913 Two component Transcriptional regulator, Winged helix family (NCBI) 0.44 Rru_A1833 3-hydroxyisobutyrate dehydrogenase (NCBI) low > 58
Brevundimonas sp. GW460-12-10-14-LB2 0.58 A4249_RS10810 response regulator transcription factor 0.57 A4249_RS03595 3-hydroxyisobutyrate dehydrogenase low > 48
Alteromonas macleodii MIT1002 0.51 MIT1002_03097 Transcriptional activator protein CopR 0.45 MIT1002_03327 3-hydroxyisobutyrate dehydrogenase 0.53 24
Shewanella loihica PV-4 0.51 Shew_0097 two component transcriptional regulator (RefSeq) 0.39 Shew_1672 3-hydroxyisobutyrate dehydrogenase (RefSeq) low > 60
Shewanella oneidensis MR-1 0.50 SO4428 DNA-binding response regulator (NCBI ptt file) 0.40 SO1682 mmsB 3-hydroxyisobutyrate dehydrogenase (NCBI ptt file) low > 76
Shewanella sp. ANA-3 0.50 Shewana3_0282 two component transcriptional regulator (RefSeq) 0.37 Shewana3_2766 3-hydroxyisobutyrate dehydrogenase (RefSeq) low > 73
Pseudomonas putida KT2440 0.48 PP_2907 DNA-binding response regulator 0.41 PP_4666 3-hydroxyisobutyrate dehydrogenase low > 96
Variovorax sp. SCN45 0.48 GFF2474 Two-component transcriptional response regulator SMc02366, LuxR family 0.44 GFF1478 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) low > 127
Shewanella amazonensis SB2B 0.48 Sama_3534 response regulator receiver protein (RefSeq) 0.39 Sama_1380 3-hydroxyisobutyrate dehydrogenase (RefSeq) — —
Pseudomonas fluorescens FW300-N2E2 0.47 Pf6N2E2_504 DNA-binding response regulator 0.40 Pf6N2E2_3451 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) low > 103
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_17925 transcriptional regulator 0.40 AO353_05985 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) low > 101
Phaeobacter inhibens DSM 17395 0.46 PGA1_c13010 two-component system response regulator 0.46 PGA1_c17360 3-hydroxyisobutyrate dehydrogenase MmsB low > 62
Pseudomonas fluorescens FW300-N1B4 0.46 Pf1N1B4_4267 DNA-binding response regulator 0.40 Pf1N1B4_1228 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) — —
Pseudomonas syringae pv. syringae B728a 0.46 Psyr_3127 Response regulator receiver:Transcriptional regulatory protein, C-terminal 0.42 Psyr_0690 3-hydroxyisobutyrate dehydrogenase low > 86
Pseudomonas fluorescens FW300-N2C3 0.46 AO356_23125 transcriptional regulator 0.40 AO356_07865 3-hydroxyisobutyrate dehydrogenase low > 104
Pseudomonas syringae pv. syringae B728a ΔmexB 0.46 Psyr_3127 Response regulator receiver:Transcriptional regulatory protein, C-terminal 0.42 Psyr_0690 3-hydroxyisobutyrate dehydrogenase low > 86
Pseudomonas fluorescens SBW25 0.46 PFLU_RS12570 response regulator transcription factor 0.41 PFLU_RS25535 3-hydroxyisobutyrate dehydrogenase low > 109
Pseudomonas simiae WCS417 0.46 PS417_11825 transcriptional regulator 0.41 PS417_23720 3-hydroxyisobutyrate dehydrogenase — —
Pseudomonas fluorescens SBW25-INTG 0.46 PFLU_RS12570 response regulator transcription factor 0.41 PFLU_RS25535 3-hydroxyisobutyrate dehydrogenase low > 109
Burkholderia phytofirmans PsJN 0.45 BPHYT_RS25955 transcriptional regulator 0.42 BPHYT_RS28025 3-hydroxyisobutyrate dehydrogenase low > 109
Paraburkholderia graminis OAS925 0.42 ABIE53_001506 two-component system copper resistance phosphate regulon response regulator CusR 0.41 ABIE53_005735 3-hydroxyisobutyrate dehydrogenase low > 113
Paraburkholderia sabiae LMG 24235 0.42 QEN71_RS15305 heavy metal response regulator transcription factor 0.40 QEN71_RS12390 3-hydroxyisobutyrate dehydrogenase low > 153
Ralstonia solanacearum GMI1000 0.42 RS_RS20255 DNA-binding response regulator 0.40 RS_RS20225 3-hydroxyisobutyrate dehydrogenase low > 80
Cupriavidus basilensis FW507-4G11 0.42 RR42_RS31535 transcriptional regulator 0.41 RR42_RS28555 3-hydroxyisobutyrate dehydrogenase — —
Herbaspirillum seropedicae SmR1 0.42 HSERO_RS15315 transcriptional regulator 0.40 HSERO_RS15390 3-hydroxyisobutyrate dehydrogenase low > 78
Pseudomonas sp. S08-1 0.42 OH686_22680 Copper-sensing two-component system response regulator CusR 0.37 OH686_05885 3-hydroxyisobutyrate dehydrogenase low > 80
Ralstonia solanacearum PSI07 0.42 RPSI07_RS02355 DNA-binding response regulator 0.41 RPSI07_RS02325 3-hydroxyisobutyrate dehydrogenase low > 81
Acidovorax sp. GW101-3H11 0.41 Ac3H11_4210 DNA-binding heavy metal response regulator 0.41 Ac3H11_2362 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) low > 79
Ralstonia solanacearum IBSBF1503 0.41 RALBFv3_RS20860 DNA-binding response regulator 0.40 RALBFv3_RS20415 3-hydroxyisobutyrate dehydrogenase low > 76
Ralstonia solanacearum UW163 0.41 UW163_RS21995 DNA-binding response regulator 0.40 UW163_RS18760 3-hydroxyisobutyrate dehydrogenase — —
Acinetobacter radioresistens SK82 0.41 MPMX26_03114 Transcriptional regulatory protein CusR 0.41 MPMX26_01549 3-hydroxyisobutyrate dehydrogenase — —
Castellaniella sp019104865 MT123 0.41 ABCV34_RS03230 heavy metal response regulator transcription factor 0.43 ABCV34_RS12490 3-hydroxyisobutyrate dehydrogenase low > 48
Paraburkholderia bryophila 376MFSha3.1 0.41 H281DRAFT_01736 two-component system, OmpR family, copper resistance phosphate regulon response regulator CusR 0.41 H281DRAFT_01201 3-hydroxyisobutyrate dehydrogenase low > 103
Ralstonia sp. UNC404CL21Col 0.40 ABZR87_RS21725 heavy metal response regulator transcription factor 0.42 ABZR87_RS17475 3-hydroxyisobutyrate dehydrogenase low > 80
Pseudomonas fluorescens GW456-L13 0.40 PfGW456L13_4017 Copper-sensing two-component system response regulator CusR 0.40 PfGW456L13_5145 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) low > 87
Pseudomonas stutzeri RCH2 0.39 Psest_0611 heavy metal response regulator 0.40 Psest_2438 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) (from data) low > 67
Mycobacterium tuberculosis H37Rv 0.37 Rv0602c Two component DNA binding transcriptional regulatory protein TcrA 0.50 Rv0751c Probable 3-hydroxyisobutyrate dehydrogenase MmsB (hibadh) low > 58

Not shown: 42 genomes with orthologs for SMc02366 only; 5 genomes with orthologs for SM_b20751 only