Conservation of cofitness between PP_2214 and PP_2216 in Pseudomonas putida KT2440

48 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pseudomonas putida KT2440 1.0 PP_2214 3-hydroxyacyl-CoA dehydrogenase type-2 1.0 PP_2216 short-chain acyl-CoA dehydrogenase 0.43 5
Pseudomonas fluorescens SBW25-INTG 0.80 PFLU_RS14760 SDR family NAD(P)-dependent oxidoreductase 0.90 PFLU_RS14770 acyl-CoA dehydrogenase 0.41 10
Pseudomonas fluorescens SBW25 0.80 PFLU_RS14760 SDR family NAD(P)-dependent oxidoreductase 0.90 PFLU_RS14770 acyl-CoA dehydrogenase low > 109
Pseudomonas sp. RS175 0.76 PFR28_01881 putative oxidoreductase 0.88 PFR28_01883 Acyl-CoA dehydrogenase 0.63 2
Pseudomonas simiae WCS417 0.75 PS417_13860 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.91 PS417_13850 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) — —
Pseudomonas fluorescens GW456-L13 0.74 PfGW456L13_2981 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) 0.89 PfGW456L13_2983 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) low > 87
Pseudomonas fluorescens FW300-N2E2 0.74 Pf6N2E2_1144 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) 0.89 Pf6N2E2_1146 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) — —
Pseudomonas fluorescens FW300-N2E3 0.74 AO353_25690 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.90 AO353_25680 2-methylbutanoyl-CoA dehydrogenase / butanoyl-CoA dehydrogenase / isobutyryl-CoA dehydrogenase (EC 1.3.8.1; EC 1.3.8.5) (from data) — —
Pseudomonas fluorescens FW300-N2C3 0.73 AO356_26345 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.89 AO356_26355 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) 0.73 3
Pseudomonas fluorescens FW300-N1B4 0.72 Pf1N1B4_4785 Probable acyl-CoA dehydrogenase (EC 1.3.99.3) 0.89 Pf1N1B4_4787 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) — —
Pseudomonas stutzeri RCH2 0.68 Psest_2447 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) 0.86 Psest_2445 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) 0.24 12
Pseudomonas sp. S08-1 0.67 OH686_00865 3-hydroxyacyl-CoA dehydrogenase or 17hydroxysteroid dehydrogenase type 10 (HSD10)-like 0.81 OH686_00875 Acyl-CoA dehydrogenase, short-chain specific low > 80
Rhodospirillum rubrum S1H 0.66 Rru_A1507 short-chain dehydrogenase/reductase SDR (NCBI) 0.38 Rru_A1835 Butyryl-CoA dehydrogenase (NCBI) low > 58
Dechlorosoma suillum PS 0.66 Dsui_1624 dehydrogenase of unknown specificity, short-chain alcohol dehydrogenase like protein 0.65 Dsui_0977 acyl-CoA dehydrogenase low > 51
Sinorhizobium meliloti 1021 0.65 SMa1452 hypothetical protein 0.40 SM_b20753 acyl-CoA dehydrogenase low > 103
Paraburkholderia bryophila 376MFSha3.1 0.65 H281DRAFT_06131 NAD(P)-dependent dehydrogenase, short-chain alcohol dehydrogenase family 0.66 H281DRAFT_02091 hypothetical protein low > 103
Rhodopseudomonas palustris CGA009 0.65 TX73_011910 3-hydroxyacyl-CoA dehydrogenase 0.74 TX73_011920 acyl-CoA dehydrogenase family protein low > 86
Paraburkholderia graminis OAS925 0.64 ABIE53_005415 NAD(P)-dependent dehydrogenase (short-subunit alcohol dehydrogenase family) 0.66 ABIE53_000588 butyryl-CoA dehydrogenase low > 113
Burkholderia phytofirmans PsJN 0.61 BPHYT_RS15890 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.66 BPHYT_RS02220 butyryl-CoA dehydrogenase low > 109
Herbaspirillum seropedicae SmR1 0.61 HSERO_RS04630 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.66 HSERO_RS04640 butyryl-CoA dehydrogenase low > 78
Ralstonia solanacearum UW163 0.61 UW163_RS08530 3-hydroxyacyl-CoA dehydrogenase 0.63 UW163_RS03075 butyryl-CoA dehydrogenase — —
Ralstonia solanacearum GMI1000 0.61 RS_RS12705 3-hydroxyacyl-CoA dehydrogenase 0.61 RS_RS01345 butyryl-CoA dehydrogenase low > 80
Ralstonia solanacearum IBSBF1503 0.61 RALBFv3_RS05095 3-hydroxyacyl-CoA dehydrogenase 0.63 RALBFv3_RS10505 butyryl-CoA dehydrogenase low > 76
Paraburkholderia sabiae LMG 24235 0.60 QEN71_RS02810 3-hydroxyacyl-CoA dehydrogenase 0.65 QEN71_RS01115 acyl-CoA dehydrogenase family protein low > 153
Hydrogenophaga sp. GW460-11-11-14-LB1 0.59 GFF3825 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) @ 17hydroxysteroid dehydrogenase type 10 (HSD10)-like 0.65 GFF1721 Butyryl-CoA dehydrogenase (EC 1.3.99.2) low > 90
Acidovorax sp. GW101-3H11 0.59 Ac3H11_2606 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) @ 17hydroxysteroid dehydrogenase type 10 (HSD10)-like 0.65 Ac3H11_2996 2-methyl-branched-chain-enoyl-CoA reductase (EC 1.3.8.5) (from data) 0.78 2
Cupriavidus basilensis FW507-4G11 0.59 RR42_RS03440 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.64 RR42_RS00895 acyl-CoA dehydrogenase low > 128
Variovorax sp. OAS795 0.58 ABID97_RS10560 3-hydroxyacyl-CoA dehydrogenase 0.66 ABID97_RS25215 acyl-CoA dehydrogenase family protein low > 91
Azospirillum sp. SherDot2 0.56 MPMX19_02389 putative oxidoreductase 0.74 MPMX19_03937 Acyl-CoA dehydrogenase low > 112
Azospirillum brasilense Sp245 0.54 AZOBR_RS26110 3-hydroxy-2-methylbutyryl-CoA dehydrogenase 0.71 AZOBR_RS22300 acyl-CoA dehydrogenase — —
Acinetobacter radioresistens SK82 0.54 MPMX26_01177 putative oxidoreductase 0.71 MPMX26_01547 Acyl-CoA dehydrogenase — —
Castellaniella sp019104865 MT123 0.54 ABCV34_RS05365 3-hydroxyacyl-CoA dehydrogenase 0.42 ABCV34_RS03995 acyl-CoA dehydrogenase family protein 0.98 3
Marinobacter adhaerens HP15 0.53 HP15_1007 3-hydroxyacyl-CoA dehydrogenase type II 0.39 HP15_907 acyl-CoA dehydrogenase domain protein low > 73
Agrobacterium fabrum C58 0.52 Atu1415 3-hydroxyacyl-CoA dehydrogenase type II 0.75 Atu3474 acyl-CoA dehydrogenase low > 89
Alteromonas macleodii MIT1002 0.51 MIT1002_01862 Levodione reductase 0.41 MIT1002_01978 Acyl-CoA dehydrogenase low > 70
Magnetospirillum magneticum AMB-1 0.51 AMB_RS18130 KR domain-containing protein 0.72 AMB_RS18215 acyl-CoA dehydrogenase low > 64
Mycobacterium tuberculosis H37Rv 0.50 Rv1144 Probable short-chain type dehydrogenase/reductase 0.38 Rv3274c Probable acyl-CoA dehydrogenase FadE25 — —
Variovorax sp. SCN45 0.49 GFF2281 Short-chain dehydrogenase/reductase SDR 0.66 GFF1995 Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.8.1) low > 127
Xanthomonas campestris pv. campestris strain 8004 0.49 Xcc-8004.2924.1 Short-chain dehydrogenase/reductase SDR 0.43 Xcc-8004.3378.1 hypothetical protein low > 74
Kangiella aquimarina DSM 16071 0.48 B158DRAFT_1000 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) 0.72 B158DRAFT_2510 Acyl-CoA dehydrogenases 0.73 2
Bosea sp. OAE506 0.46 ABIE41_RS04860 SDR family NAD(P)-dependent oxidoreductase 0.38 ABIE41_RS23925 isobutyryl-CoA dehydrogenase low > 77
Brevundimonas sp. GW460-12-10-14-LB2 0.44 A4249_RS12825 SDR family oxidoreductase 0.40 A4249_RS03585 isobutyryl-CoA dehydrogenase low > 48
Caulobacter crescentus NA1000 0.40 CCNA_00123 3-hydroxyacyl CoA dehydrogenase 0.41 CCNA_01412 acyl-CoA dehydrogenase, short-chain specific low > 66
Caulobacter crescentus NA1000 Δfur 0.40 CCNA_00123 3-hydroxyacyl CoA dehydrogenase 0.41 CCNA_01412 acyl-CoA dehydrogenase, short-chain specific low > 67
Sphingomonas koreensis DSMZ 15582 0.39 Ga0059261_2816 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) 0.38 Ga0059261_3793 Acyl-CoA dehydrogenases low > 68
Shewanella loihica PV-4 0.29 Shew_1673 fabG 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) 0.43 Shew_1669 butyryl-CoA dehydrogenase (RefSeq) 0.46 31
Shewanella amazonensis SB2B 0.29 Sama_1381 fabG 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) 0.42 Sama_1377 butyryl-CoA dehydrogenase (RefSeq) low > 62
Shewanella sp. ANA-3 0.28 Shewana3_2765 fabG 3-ketoacyl-(acyl-carrier-protein) reductase (RefSeq) 0.44 Shewana3_2769 Branched-chain acyl-CoA dehydrogenase (EC 1.3.99.12) (from data) — —
Shewanella oneidensis MR-1 0.27 SO1683 3-hydroxy-2-methylbutyryl-CoA dehydrogenase IvdG (EC:1.1.1.178) (from data) 0.43 SO1679 2-methylbutanoyl-CoA dehydrogenase (EC 1.3.8.5) (from data) low > 76

Not shown: 11 genomes with orthologs for PP_2214 only; 20 genomes with orthologs for PP_2216 only