Conservation of cofitness between OKFHMN_20250 and OKFHMN_20060 in Escherichia coli ECRC100

61 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECRC100 1.0 OKFHMN_20250 relA GTP diphosphokinase 1.0 OKFHMN_20060 argA amino-acid N-acetyltransferase 0.76 13
Escherichia coli ECRC99 1.00 KEDOAH_07880 relA GTP diphosphokinase 1.00 KEDOAH_08070 argA amino-acid N-acetyltransferase
Escherichia coli BW25113 1.00 b2784 relA (p)ppGpp synthetase I/GTP pyrophosphokinase (NCBI) 1.00 b2818 argA N-acetylglutamate synthase (NCBI) 0.48 65
Escherichia coli ECRC98 1.00 JDDGAC_23915 relA GTP diphosphokinase 1.00 JDDGAC_23725 argA amino-acid N-acetyltransferase low > 86
Escherichia coli ECRC62 1.00 BNILDI_10630 relA GTP diphosphokinase 1.00 BNILDI_10425 argA amino-acid N-acetyltransferase low > 75
Escherichia coli ECRC102 1.00 NIAGMN_18020 relA GTP diphosphokinase 1.00 NIAGMN_17830 argA amino-acid N-acetyltransferase
Escherichia coli ECOR27 1.00 NOLOHH_12125 relA GTP diphosphokinase 1.00 NOLOHH_11945 argA amino-acid N-acetyltransferase low > 75
Escherichia coli ECOR38 1.00 HEPCGN_19500 relA GTP diphosphokinase 1.00 HEPCGN_19315 argA amino-acid N-acetyltransferase 0.78 58
Escherichia coli BL21 1.00 ECD_02629 (p)ppGpp synthetase I/GTP pyrophosphokinase 1.00 ECD_02666 amino acid N-acetyltransferase and inactive acetylglutamate kinase low > 61
Escherichia coli ECRC101 1.00 MCAODC_10775 relA GTP diphosphokinase 1.00 MCAODC_10585 argA amino-acid N-acetyltransferase low > 87
Escherichia coli Nissle 1917 1.00 ECOLIN_RS15515 GTP diphosphokinase 1.00 ECOLIN_RS15820 amino-acid N-acetyltransferase low > 55
Escherichia fergusonii Becca 1.00 EFB2_01133 GTP pyrophosphokinase 1.00 EFB2_01066 Amino-acid acetyltransferase low > 86
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_00947 GTP pyrophosphokinase 1.00 OHPLBJKB_00912 Amino-acid acetyltransferase low > 73
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.96 GFF4837 'GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2)' transl_table=11 0.94 GFF1299 N-acetylglutamate synthase (EC 2.3.1.1) low > 78
Klebsiella michiganensis M5al 0.94 BWI76_RS22805 GTP diphosphokinase 0.93 BWI76_RS23220 amino-acid N-acetyltransferase 0.57 23
Enterobacter asburiae PDN3 0.94 EX28DRAFT_2864 (p)ppGpp synthetase, RelA/SpoT family 0.94 EX28DRAFT_2893 N-acetylglutamate synthase (EC 2.3.1.1) low > 76
Enterobacter sp. TBS_079 0.93 MPMX20_03653 GTP pyrophosphokinase 0.94 MPMX20_03681 Amino-acid acetyltransferase 0.44 64
Dickeya dadantii 3937 0.87 DDA3937_RS17015 GTP diphosphokinase 0.86 DDA3937_RS04990 amino-acid N-acetyltransferase low > 74
Dickeya dianthicola 67-19 0.87 HGI48_RS17070 GTP diphosphokinase 0.86 HGI48_RS05000 amino-acid N-acetyltransferase low > 71
Dickeya dianthicola ME23 0.87 DZA65_RS18145 GTP diphosphokinase 0.86 DZA65_RS05340 amino-acid N-acetyltransferase low > 75
Pectobacterium carotovorum WPP14 0.86 HER17_RS04115 GTP diphosphokinase 0.88 HER17_RS16505 amino-acid N-acetyltransferase low > 75
Erwinia tracheiphila SCR3 0.86 LU632_RS06350 relA GTP diphosphokinase 0.87 LU632_RS06210 argA amino-acid N-acetyltransferase low > 74
Serratia liquefaciens MT49 0.85 IAI46_03600 GTP diphosphokinase 0.89 IAI46_20395 amino-acid N-acetyltransferase 0.76 14
Rahnella sp. WP5 0.85 EX31_RS07955 GTP diphosphokinase 0.88 EX31_RS13160 amino-acid N-acetyltransferase 0.88 25
Pantoea sp. MT58 0.84 IAI47_04120 GTP diphosphokinase 0.89 IAI47_03975 amino-acid N-acetyltransferase 0.52 19
Vibrio cholerae E7946 ATCC 55056 0.67 CSW01_12405 GTP diphosphokinase 0.65 CSW01_11765 amino-acid N-acetyltransferase low > 62
Shewanella sp. ANA-3 0.59 Shewana3_1111 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) 0.68 Shewana3_3767 N-acetylglutamate synthase (RefSeq) 0.80 65
Shewanella amazonensis SB2B 0.58 Sama_1033 GTP diphosphokinase (RefSeq) 0.68 Sama_0330 N-acetylglutamate synthase (RefSeq) 0.88 52
Shewanella oneidensis MR-1 0.58 SO3455 relA GTP pyrophosphokinase (NCBI ptt file) 0.68 SO4245 argA amino-acid acetyltransferase (NCBI ptt file) 0.89 45
Shewanella loihica PV-4 0.58 Shew_1202 (p)ppGpp synthetase I, SpoT/RelA (RefSeq) 0.67 Shew_3478 N-acetylglutamate synthase (RefSeq) 0.87 37
Alteromonas macleodii MIT1002 0.53 MIT1002_00794 GTP pyrophosphokinase 0.49 MIT1002_00466 Amino-acid acetyltransferase low > 70
Pseudomonas sp. RS175 0.47 PFR28_03223 GTP pyrophosphokinase 0.51 PFR28_04308 Amino-acid acetyltransferase 0.48 13
Pseudomonas fluorescens GW456-L13 0.47 PfGW456L13_2035 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) 0.49 PfGW456L13_913 N-acetylglutamate synthase (EC 2.3.1.1) 0.42 49
Pseudomonas fluorescens FW300-N2C3 0.47 AO356_19060 (p)ppGpp synthetase 0.51 AO356_13085 N-acetylglutamate synthase 0.40 42
Pseudomonas sp. S08-1 0.47 OH686_18960 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase , (p)ppGpp synthetase I 0.50 OH686_11120 amino-acid N-acetyltransferase low > 80
Pseudomonas fluorescens FW300-N2E2 0.47 Pf6N2E2_5723 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) 0.51 Pf6N2E2_4497 N-acetylglutamate synthase (EC 2.3.1.1)
Pseudomonas fluorescens FW300-N2E3 0.47 AO353_02710 (p)ppGpp synthetase 0.49 AO353_08685 N-acetylglutamate synthase 0.50 44
Pseudomonas fluorescens SBW25 0.47 PFLU_RS22095 GTP diphosphokinase 0.50 PFLU_RS28855 amino-acid N-acetyltransferase
Pseudomonas fluorescens SBW25-INTG 0.47 PFLU_RS22095 GTP diphosphokinase 0.50 PFLU_RS28855 amino-acid N-acetyltransferase
Pseudomonas fluorescens FW300-N1B4 0.47 Pf1N1B4_3508 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I / Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase (EC 3.1.7.2) 0.49 Pf1N1B4_2243 N-acetylglutamate synthase (EC 2.3.1.1)
Pseudomonas simiae WCS417 0.47 PS417_20150 (p)ppGpp synthetase 0.50 PS417_27195 N-acetylglutamate synthase
Pseudomonas syringae pv. syringae B728a 0.47 Psyr_3695 RelA/SpoT protein 0.48 Psyr_0254 N-acetylglutamate synthase
Pseudomonas syringae pv. syringae B728a ΔmexB 0.47 Psyr_3695 RelA/SpoT protein 0.48 Psyr_0254 N-acetylglutamate synthase
Pseudomonas putida KT2440 0.46 PP_1656 ATP:GTP 3'-pyrophosphotransferase 0.50 PP_5185 acetylglutamate kinase-like protein (regulatory domain)/amino acid N-acetyltransferase low > 96
Pseudomonas stutzeri RCH2 0.46 Psest_1640 (p)ppGpp synthetase, RelA/SpoT family 0.51 Psest_4000 amino-acid N-acetyltransferase
Marinobacter adhaerens HP15 0.45 HP15_791 (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA 0.48 HP15_3314 N-acetyllutamate synthase low > 73
Dechlorosoma suillum PS 0.37 Dsui_2816 (p)ppGpp synthetase, RelA/SpoT family 0.42 Dsui_1570 amino-acid N-acetyltransferase
Herbaspirillum seropedicae SmR1 0.36 HSERO_RS09855 GTP pyrophosphokinase 0.45 HSERO_RS17320 amino acid acetyltransferase
Ralstonia sp. UNC404CL21Col 0.36 ABZR87_RS13745 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.42 ABZR87_RS11015 amino-acid N-acetyltransferase low > 80
Acinetobacter radioresistens SK82 0.36 MPMX26_00539 GTP pyrophosphokinase 0.50 MPMX26_00029 Amino-acid acetyltransferase low > 36
Ralstonia solanacearum PSI07 0.36 RPSI07_RS15685 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.44 RPSI07_RS17870 amino-acid N-acetyltransferase low > 81
Ralstonia solanacearum GMI1000 0.36 RS_RS07930 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.44 RS_RS06265 amino-acid N-acetyltransferase
Paraburkholderia sabiae LMG 24235 0.36 QEN71_RS05265 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.45 QEN71_RS05620 amino-acid N-acetyltransferase
Ralstonia solanacearum UW163 0.35 UW163_RS15115 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.44 UW163_RS12945 amino-acid N-acetyltransferase
Ralstonia solanacearum IBSBF1503 0.35 RALBFv3_RS01805 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.44 RALBFv3_RS15485 amino-acid N-acetyltransferase low > 76
Cupriavidus basilensis FW507-4G11 0.35 RR42_RS06585 GTP pyrophosphokinase 0.44 RR42_RS13035 amino acid acetyltransferase
Burkholderia phytofirmans PsJN 0.35 BPHYT_RS13655 GTP pyrophosphokinase 0.44 BPHYT_RS12985 amino acid acetyltransferase low > 109
Paraburkholderia bryophila 376MFSha3.1 0.34 H281DRAFT_04499 GTP pyrophosphokinase 0.44 H281DRAFT_00444 N-acetylglutamate synthase low > 103
Paraburkholderia graminis OAS925 0.34 ABIE53_002905 GTP pyrophosphokinase 0.44 ABIE53_002814 amino-acid N-acetyltransferase
Acidovorax sp. GW101-3H11 0.33 Ac3H11_362 GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I 0.43 Ac3H11_900 N-acetylglutamate synthase (EC 2.3.1.1)
Castellaniella sp019104865 MT123 0.33 ABCV34_RS08440 bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase 0.39 ABCV34_RS02415 amino-acid N-acetyltransferase
Variovorax sp. SCN45 0.32 GFF403 Inactive (p)ppGpp 3'-pyrophosphohydrolase domain / GTP pyrophosphokinase (EC 2.7.6.5), (p)ppGpp synthetase I 0.45 GFF249 N-acetylglutamate synthase (EC 2.3.1.1)

Not shown: 10 genomes with orthologs for OKFHMN_20250 only; 2 genomes with orthologs for OKFHMN_20060 only