Conservation of cofitness between HER17_RS10965 and HER17_RS12790 in Pectobacterium carotovorum WPP14

68 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Pectobacterium carotovorum WPP14 1.0 HER17_RS10965 acyl-CoA thioester hydrolase YciA 1.0 HER17_RS12790 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase 0.71 9
Dickeya dadantii 3937 0.89 DDA3937_RS10430 acyl-CoA thioester hydrolase YciA 0.93 DDA3937_RS09325 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 74
Dickeya dianthicola ME23 0.89 DZA65_RS10910 acyl-CoA thioester hydrolase YciA 0.92 DZA65_RS09655 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 75
Dickeya dianthicola 67-19 0.88 HGI48_RS10435 acyl-CoA thioester hydrolase YciA 0.93 HGI48_RS09350 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 71
Rahnella sp. WP5 0.85 EX31_RS10010 acyl-CoA thioester hydrolase YciA 0.94 EX31_RS18715 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 89
Serratia liquefaciens MT49 0.84 IAI46_14085 acyl-CoA thioester hydrolase YciA 0.94 IAI46_07885 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 86
Enterobacter asburiae PDN3 0.80 EX28DRAFT_0923 Acyl-CoA hydrolase 0.79 EX28DRAFT_1257 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Pantoea sp. MT58 0.80 IAI47_09135 acyl-CoA thioester hydrolase YciA 0.91 IAI47_06705 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Enterobacter sp. TBS_079 0.80 MPMX20_02575 putative acyl-CoA thioester hydrolase 0.79 MPMX20_02209 S-(hydroxymethyl)glutathione dehydrogenase low > 85
Klebsiella michiganensis M5al 0.79 BWI76_RS11790 acyl-CoA thioesterase 0.80 BWI76_RS13260 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 92
Escherichia coli HS(pFamp)R (ATCC 700891) 0.79 OHPLBJKB_02430 putative acyl-CoA thioester hydrolase 0.72 OHPLBJKB_03314 S-(hydroxymethyl)glutathione dehydrogenase low > 73
Escherichia coli BW25113 0.79 b1253 yciA predicted hydrolase (NCBI) 0.71 b0356 frmA alcohol dehydrogenase class III/glutathione-dependent formaldehyde dehydrogenase (NCBI) low > 76
Escherichia coli ECOR38 0.79 HEPCGN_25145 yciA acyl-CoA thioester hydrolase YciA 0.72 HEPCGN_07365 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 87
Escherichia coli BL21 0.79 ECD_01227 acyl-CoA esterase 0.72 ECD_00310 alcohol dehydrogenase class III; glutathione-dependent formaldehyde dehydrogenase low > 61
Escherichia coli Nissle 1917 0.79 ECOLIN_RS07565 acyl-CoA thioester hydrolase YciA 0.71 ECOLIN_RS02210 S-(hydroxymethyl)glutathione dehydrogenase low > 55
Escherichia fergusonii Becca 0.79 EFB2_02672 putative acyl-CoA thioester hydrolase 0.71 EFB2_03694 S-(hydroxymethyl)glutathione dehydrogenase low > 86
Escherichia coli ECOR27 0.79 NOLOHH_20370 yciA acyl-CoA thioester hydrolase YciA 0.72 NOLOHH_01650 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 75
Escherichia coli ECRC62 0.79 BNILDI_18515 yciA acyl-CoA thioester hydrolase YciA 0.72 BNILDI_23065 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 75
Escherichia coli ECRC99 0.79 KEDOAH_25675 yciA acyl-CoA thioester hydrolase YciA 0.72 KEDOAH_19230 frmA S-(hydroxymethyl)glutathione dehydrogenase — —
Escherichia coli ECRC102 0.79 NIAGMN_27555 yciA acyl-CoA thioester hydrolase YciA 0.72 NIAGMN_06795 frmA S-(hydroxymethyl)glutathione dehydrogenase — —
Escherichia coli ECRC101 0.79 MCAODC_21580 yciA acyl-CoA thioester hydrolase YciA 0.72 MCAODC_27970 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 87
Escherichia coli ECRC100 0.79 OKFHMN_28680 yciA acyl-CoA thioester hydrolase YciA 0.72 OKFHMN_08740 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 80
Escherichia coli ECRC98 0.79 JDDGAC_05895 yciA acyl-CoA thioester hydrolase YciA 0.72 JDDGAC_12395 frmA S-(hydroxymethyl)glutathione dehydrogenase low > 86
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.77 GFF2735 Acyl-CoA thioesterase YciA, involved in membrane biogenesis 0.76 GFF2617 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 78
Dinoroseobacter shibae DFL-12 0.52 Dshi_2218 thioesterase superfamily protein (RefSeq) 0.64 Dshi_0103 Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase (RefSeq) low > 64
Acinetobacter radioresistens SK82 0.48 MPMX26_02646 putative acyl-CoA thioester hydrolase 0.78 MPMX26_01472 S-(hydroxymethyl)glutathione dehydrogenase low > 36
Azospirillum brasilense Sp245 0.47 AZOBR_RS22235 acyl-CoA thioester hydrolase 0.83 AZOBR_RS16515 S-(hydroxymethyl)glutathione dehydrogenase low > 97
Bosea sp. OAE506 0.47 ABIE41_RS12055 acyl-CoA thioesterase 0.66 ABIE41_RS09635 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 77
Brevundimonas sp. GW460-12-10-14-LB2 0.46 A4249_RS12320 acyl-CoA thioesterase 0.62 A4249_RS00420 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 48
Rhodospirillum rubrum S1H 0.45 Rru_A2709 Thioesterase superfamily (NCBI) 0.83 Rru_A3405 Formaldehyde dehydrogenase (glutathione) (NCBI) low > 58
Azospirillum sp. SherDot2 0.45 MPMX19_00971 putative acyl-CoA thioester hydrolase 0.79 MPMX19_05326 S-(hydroxymethyl)glutathione dehydrogenase low > 112
Pseudomonas syringae pv. syringae B728a ΔmexB 0.44 Psyr_5043 Thioesterase superfamily 0.81 Psyr_1367 Zinc-containing alcohol dehydrogenase superfamily low > 86
Hydrogenophaga sp. GW460-11-11-14-LB1 0.44 GFF516 Acyl-CoA hydrolase (EC 3.1.2.20) 0.67 GFF3318 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 90
Pseudomonas syringae pv. syringae B728a 0.44 Psyr_5043 Thioesterase superfamily 0.81 Psyr_1367 Zinc-containing alcohol dehydrogenase superfamily low > 86
Caulobacter crescentus NA1000 0.44 CCNA_00190 acyl-CoA hydrolase 0.62 CCNA_02601 glutathione-dependent formaldehyde dehydrogenase low > 66
Pseudomonas sp. RS175 0.44 PFR28_04491 putative acyl-CoA thioester hydrolase 0.82 PFR28_00420 S-(hydroxymethyl)glutathione dehydrogenase low > 88
Caulobacter crescentus NA1000 Δfur 0.44 CCNA_00190 acyl-CoA hydrolase 0.62 CCNA_02601 glutathione-dependent formaldehyde dehydrogenase low > 67
Pseudomonas fluorescens FW300-N2E2 0.44 Pf6N2E2_4077 cytosolic long-chain acyl-CoA thioester hydrolase family protein 0.82 Pf6N2E2_3044 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 103
Pseudomonas fluorescens FW300-N2C3 0.44 AO356_11055 long-chain acyl-CoA thioester hydrolase 0.82 AO356_05920 S-(hydroxymethyl)glutathione dehydrogenase 0.28 36
Pseudomonas simiae WCS417 0.43 PS417_28095 long-chain acyl-CoA thioester hydrolase 0.83 PS417_06330 S-(hydroxymethyl)glutathione dehydrogenase — —
Pseudomonas fluorescens SBW25 0.43 PFLU_RS29780 acyl-CoA thioesterase 0.82 PFLU_RS06395 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 109
Pseudomonas fluorescens SBW25-INTG 0.43 PFLU_RS29780 acyl-CoA thioesterase 0.82 PFLU_RS06395 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 109
Pseudomonas fluorescens GW456-L13 0.43 PfGW456L13_751 cytosolic long-chain acyl-CoA thioester hydrolase family protein 0.83 PfGW456L13_3630 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 87
Pseudomonas fluorescens FW300-N2E3 0.43 AO353_09915 long-chain acyl-CoA thioester hydrolase 0.82 AO353_16580 S-(hydroxymethyl)glutathione dehydrogenase low > 101
Marinobacter adhaerens HP15 0.43 HP15_3390 thioesterase superfamily protein 0.80 HP15_4017 formaldehyde dehydrogenase (glutathione-dependent) low > 73
Pseudomonas fluorescens FW300-N1B4 0.43 Pf1N1B4_2032 cytosolic long-chain acyl-CoA thioester hydrolase family protein 0.81 Pf1N1B4_3108 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) — —
Pseudomonas putida KT2440 0.43 PP_5331 Long-chain acyl-CoA thioester hydrolase 0.82 PP_1616 formaldehyde dehydrogenase, glutathione-dependent low > 96
Agrobacterium fabrum C58 0.43 Atu3861 acyl-CoA hydrolase 0.59 Atu1670 alcohol dehydrogenase class III low > 89
Magnetospirillum magneticum AMB-1 0.43 AMB_RS16945 acyl-CoA thioesterase 0.12 AMB_RS10835 6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase low > 64
Pseudomonas sp. S08-1 0.43 OH686_13400 cytosolic long-chain acyl-CoA thioester hydrolase family protein 0.83 OH686_18150 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 80
Acidovorax sp. GW101-3H11 0.43 Ac3H11_1945 Acyl-CoA hydrolase (EC 3.1.2.20) 0.75 Ac3H11_3163 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 79
Pseudomonas stutzeri RCH2 0.43 Psest_0218 Acyl-CoA hydrolase 0.81 Psest_2816 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 67
Ralstonia solanacearum IBSBF1503 0.42 RALBFv3_RS11535 acyl-CoA thioesterase 0.69 RALBFv3_RS12345 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 76
Ralstonia solanacearum UW163 0.42 UW163_RS02050 acyl-CoA thioesterase 0.69 UW163_RS01260 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase — —
Ralstonia solanacearum PSI07 0.42 RPSI07_RS21675 acyl-CoA thioesterase 0.69 RPSI07_RS20965 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 81
Variovorax sp. OAS795 0.42 ABID97_RS05905 acyl-CoA thioesterase 0.67 ABID97_RS10235 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 91
Cupriavidus basilensis FW507-4G11 0.42 RR42_RS02530 acyl-CoA hydrolase 0.68 RR42_RS25775 alcohol dehydrogenase — —
Sinorhizobium meliloti 1021 0.42 SMc04228 hypothetical protein 0.61 SM_b20170 glutathione-dependent formaldehyde dehydrogenase — —
Variovorax sp. SCN45 0.42 GFF4599 Acyl-CoA hydrolase (EC 3.1.2.20) 0.66 GFF2941 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) low > 127
Castellaniella sp019104865 MT123 0.41 ABCV34_RS09595 acyl-CoA thioesterase 0.70 ABCV34_RS09045 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 48
Ralstonia solanacearum GMI1000 0.41 RS_RS02365 acyl-CoA thioesterase 0.68 RS_RS17530 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 80
Paraburkholderia graminis OAS925 0.41 ABIE53_000793 acyl-CoA thioesterase YciA 0.66 ABIE53_003402 S-(hydroxymethyl)glutathione dehydrogenase/alcohol dehydrogenase low > 113
Ralstonia sp. UNC404CL21Col 0.41 ABZR87_RS07500 acyl-CoA thioesterase 0.69 ABZR87_RS08285 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 80
Paraburkholderia bryophila 376MFSha3.1 0.41 H281DRAFT_04633 (3S)-malyl-CoA thioesterase 0.66 H281DRAFT_04166 S-(hydroxymethyl)glutathione dehydrogenase / alcohol dehydrogenase low > 103
Rhizobium sp. OAE497 0.40 ABIE40_RS10785 acyl-CoA thioesterase 0.60 ABIE40_RS09860 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 107
Paraburkholderia sabiae LMG 24235 0.40 QEN71_RS02095 acyl-CoA thioesterase 0.67 QEN71_RS02555 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 153
Burkholderia phytofirmans PsJN 0.39 BPHYT_RS03270 acyl-CoA hydrolase 0.75 BPHYT_RS00510 S-(hydroxymethyl)glutathione dehydrogenase low > 109
Sphingomonas koreensis DSMZ 15582 0.38 Ga0059261_3714 Acyl-CoA hydrolase 0.65 Ga0059261_1819 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase low > 68
Herbaspirillum seropedicae SmR1 0.38 HSERO_RS19275 acyl-CoA hydrolase 0.66 HSERO_RS13615 alcohol dehydrogenase low > 78

Not shown: 2 genomes with orthologs for HER17_RS10965 only; 20 genomes with orthologs for HER17_RS12790 only