Conservation of cofitness between HEPCGN_21000 and HEPCGN_21730 in Escherichia coli ECOR38

69 genomes with putative orthologs of both genes

Organism Ratio1 Gene1 Name1 Description1 Ratio2 Gene2 Name2 Description2 Cofit Rank
Escherichia coli ECOR38 1.0 HEPCGN_21000 bepA beta-barrel assembly-enhancing protease 1.0 HEPCGN_21730 mlaA phospholipid-binding lipoprotein MlaA 0.47 18
Escherichia coli ECOR27 1.00 NOLOHH_13485 bepA beta-barrel assembly-enhancing protease 0.99 NOLOHH_14170 mlaA phospholipid-binding lipoprotein MlaA low > 76
Escherichia coli BW25113 1.00 b2494 yfgC predicted peptidase (NCBI) 0.99 b2346 vacJ predicted lipoprotein (NCBI) 0.42 25
Escherichia coli BL21 1.00 ECD_02386 OM protein maintenance and assembly metalloprotease and chaperone, periplasmic 0.99 ECD_02272 ABC transporter maintaining OM lipid asymmetry, OM lipoprotein component
Escherichia coli HS(pFamp)R (ATCC 700891) 1.00 OHPLBJKB_01232 Beta-barrel assembly-enhancing protease 0.99 OHPLBJKB_01360 putative phospholipid-binding lipoprotein MlaA 0.54 24
Escherichia coli ECRC62 1.00 BNILDI_12295 bepA beta-barrel assembly-enhancing protease 0.99 BNILDI_13080 mlaA phospholipid-binding lipoprotein MlaA low > 75
Escherichia coli ECRC99 1.00 KEDOAH_06385 bepA beta-barrel assembly-enhancing protease 0.99 KEDOAH_05660 mlaA phospholipid-binding lipoprotein MlaA
Escherichia coli ECRC102 0.99 NIAGMN_19605 bepA beta-barrel assembly-enhancing protease 0.99 NIAGMN_20310 mlaA phospholipid-binding lipoprotein MlaA low > 80
Escherichia coli ECRC98 0.99 JDDGAC_25780 bepA beta-barrel assembly-enhancing protease 0.99 JDDGAC_26495 mlaA phospholipid-binding lipoprotein MlaA low > 87
Escherichia fergusonii Becca 0.99 EFB2_01404 Beta-barrel assembly-enhancing protease 0.99 EFB2_01514 Intermembrane phospholipid transport system lipoprotein MlaA low > 86
Escherichia coli ECRC100 0.99 OKFHMN_21835 bepA beta-barrel assembly-enhancing protease 0.99 OKFHMN_22535 mlaA phospholipid-binding lipoprotein MlaA low > 79
Escherichia coli Nissle 1917 0.99 ECOLIN_RS14165 beta-barrel assembly-enhancing protease 0.99 ECOLIN_RS13570 phospholipid-binding lipoprotein MlaA low > 55
Escherichia coli ECRC101 0.99 MCAODC_12365 bepA beta-barrel assembly-enhancing protease 0.99 MCAODC_13565 mlaA phospholipid-binding lipoprotein MlaA 0.34 7
Salmonella enterica subsp. enterica serovar Typhimurium str. MS1868 0.93 GFF2175 Exported zinc metalloprotease YfgC precursor 0.97 GFF1958 Lipoprotein low > 78
Enterobacter asburiae PDN3 0.91 EX28DRAFT_0178 Putative Zn-dependent protease, contains TPR repeats 0.92 EX28DRAFT_0267 Surface lipoprotein low > 76
Enterobacter sp. TBS_079 0.90 MPMX20_03344 Beta-barrel assembly-enhancing protease 0.92 MPMX20_03272 Intermembrane phospholipid transport system lipoprotein MlaA low > 85
Klebsiella michiganensis M5al 0.85 BWI76_RS20925 peptidase M48 0.88 BWI76_RS20475 phospholipid-binding lipoprotein MlaA 0.39 7
Klebsiella pneumoniae MKP103 0.82 KDGMDA_27765 beta-barrel assembly-enhancing protease 0.91 KDGMDA_27310 phospholipid-binding lipoprotein MlaA low > 95
Pantoea sp. MT58 0.74 IAI47_05205 M48 family metallopeptidase 0.77 IAI47_06110 phospholipid-binding lipoprotein MlaA low > 76
Pantoea agglomerans CFBP13505 P0401 0.74 PagCFBP13505_RS15095 M48 family metallopeptidase 0.76 PagCFBP13505_RS00065 phospholipid-binding lipoprotein MlaA 0.82 5
Erwinia tracheiphila SCR3 0.71 LU632_RS08305 M48 family metallopeptidase 0.70 LU632_RS07300 mlaA phospholipid-binding lipoprotein MlaA low > 74
Erwinia tracheiphila HP pepo 2.2 0.71 IJEDHG_18400 Beta-barrel assembly-enhancing protease 0.70 IJEDHG_17775 mlaA phospholipid-binding lipoprotein MlaA low > 61
Pectobacterium carotovorum WPP14 0.71 HER17_RS15440 M48 family metallopeptidase 0.73 HER17_RS06855 phospholipid-binding lipoprotein MlaA low > 75
Serratia liquefaciens MT49 0.70 IAI46_18840 M48 family metallopeptidase 0.78 IAI46_18065 phospholipid-binding lipoprotein MlaA low > 86
Erwinia amylovora T8 0.70 OLJFJH_10615 Beta-barrel assembly-enhancing protease 0.71 OLJFJH_11120 phospholipid-binding lipoprotein MlaA low > 58
Rahnella sp. WP5 0.69 EX31_RS22720 M48 family metallopeptidase 0.76 EX31_RS19725 phospholipid-binding lipoprotein MlaA low > 89
Dickeya dadantii 3937 0.66 DDA3937_RS06050 M48 family metallopeptidase 0.71 DDA3937_RS14625 phospholipid-binding lipoprotein MlaA 0.64 1
Dickeya dianthicola ME23 0.66 DZA65_RS06445 M48 family metallopeptidase 0.71 DZA65_RS15515 phospholipid-binding lipoprotein MlaA 0.49 39
Dickeya dianthicola 67-19 0.66 HGI48_RS06095 M48 family metallopeptidase 0.68 HGI48_RS14575 phospholipid-binding lipoprotein MlaA low > 71
Vibrio cholerae E7946 ATCC 55056 0.41 CSW01_10785 hypothetical protein 0.40 CSW01_10245 ABC transporter low > 62
Shewanella loihica PV-4 0.39 Shew_1841 peptidase M48, Ste24p (RefSeq) 0.32 Shew_1395 VacJ family lipoprotein (RefSeq) low > 60
Shewanella oneidensis MR-1 0.38 SO2869 conserved hypothetical protein (NCBI ptt file) 0.31 SO3197 vacJ lipoprotein, putative (NCBI ptt file) 0.35 55
Shewanella sp. ANA-3 0.38 Shewana3_1649 peptidase M48, Ste24p (RefSeq) 0.31 Shewana3_1371 VacJ family lipoprotein (RefSeq) low > 73
Shewanella amazonensis SB2B 0.37 Sama_1913 peptidase M48, Ste24p (RefSeq) 0.32 Sama_2268 vacJ lipoprotein, putative (RefSeq) 0.50 31
Alteromonas macleodii MIT1002 0.35 MIT1002_02211 TPR repeat-containing protein YfgC precursor 0.30 MIT1002_00969 putative phospholipid-binding lipoprotein MlaA precursor low > 70
Pseudomonas putida KT2440 0.24 PP_1232 conserved exported protein of unknown function 0.22 PP_2163 VacJ lipoprotein 0.46 4
Pseudomonas sp. RS175 0.24 PFR28_00694 Beta-barrel assembly-enhancing protease 0.21 PFR28_01139 Intermembrane phospholipid transport system lipoprotein MlaA 0.32 14
Kangiella aquimarina DSM 16071 0.24 B158DRAFT_2440 Putative Zn-dependent protease, contains TPR repeats 0.21 B158DRAFT_1335 Surface lipoprotein low > 40
Pseudomonas fluorescens FW300-N2E2 0.24 Pf6N2E2_2752 Exported zinc metalloprotease YfgC precursor 0.21 Pf6N2E2_2261 VacJ-like lipoprotein precursor 0.35 7
Pseudomonas sp. BP01 0.24 JOY50_RS01735 M48 family metalloprotease 0.22 JOY50_RS25175 VacJ family lipoprotein low > 84
Pseudomonas sp. S08-1 0.24 OH686_19195 Exported zinc metalloprotease YfgC precursor 0.23 OH686_22720 Outer-membrane-phospholipid-binding lipoprotein MlaA low > 80
Pseudomonas fluorescens FW300-N2C3 0.24 AO356_04555 peptidase M48 0.21 AO356_02190 hypothetical protein 0.59 3
Pseudomonas sp. SVBP6 0.23 COO64_RS20220 M48 family metalloprotease 0.22 COO64_RS09535 VacJ family lipoprotein low > 93
Pseudomonas fluorescens FW300-N2E3 0.23 AO353_17645 peptidase M48 0.23 AO353_00330 hypothetical protein low > 101
Pseudomonas fluorescens GW456-L13 0.22 PfGW456L13_4512 Exported zinc metalloprotease YfgC precursor 0.23 PfGW456L13_4012 VacJ-like lipoprotein precursor low > 87
Pseudomonas sp. DMC3 0.22 GFF2281 Beta-barrel assembly-enhancing protease 0.22 GFF1301 Intermembrane phospholipid transport system lipoprotein MlaA 0.93 2
Pseudomonas syringae pv. syringae B728a ΔmexB 0.22 Psyr_1543 Peptidase M48, Ste24p 0.21 Psyr_1910 VacJ-like lipoprotein low > 86
Pseudomonas syringae pv. syringae B728a 0.22 Psyr_1543 Peptidase M48, Ste24p 0.21 Psyr_1910 VacJ-like lipoprotein low > 86
Pseudomonas fluorescens FW300-N1B4 0.22 Pf1N1B4_3327 Exported zinc metalloprotease YfgC precursor 0.21 Pf1N1B4_62 VacJ-like lipoprotein precursor
Pseudomonas lactucae CFBP13502 0.22 GEMAOFIL_01576 Beta-barrel assembly-enhancing protease 0.22 GEMAOFIL_01674 Intermembrane phospholipid transport system lipoprotein MlaA low > 93
Pseudomonas stutzeri RCH2 0.22 Psest_1510 Putative Zn-dependent protease, contains TPR repeats 0.22 Psest_2712 Surface lipoprotein 0.32 23
Pseudomonas simiae WCS417 0.21 PS417_07140 peptidase M48 0.22 PS417_07710 membrane protein low > 88
Pseudomonas fluorescens SBW25 0.21 PFLU_RS07250 M48 family metallopeptidase 0.22 PFLU_RS07785 VacJ family lipoprotein 0.77 12
Pseudomonas fluorescens SBW25-INTG 0.21 PFLU_RS07250 M48 family metallopeptidase 0.22 PFLU_RS07785 VacJ family lipoprotein 0.35 109
Pseudomonas segetis P6 0.21 MPMX49_01697 Beta-barrel assembly-enhancing protease 0.22 MPMX49_01908 Intermembrane phospholipid transport system lipoprotein MlaA 0.70 22
Dechlorosoma suillum PS 0.21 Dsui_0003 putative Zn-dependent protease 0.26 Dsui_1401 surface lipoprotein 0.80 4
Pseudomonas aeruginosa PA14 0.21 IKLFDK_04560 peptidase M48 0.23 IKLFDK_14170 VacJ family lipoprotein low > 100
Rhodanobacter denitrificans FW104-10B01 0.19 LRK54_RS15035 M48 family metalloprotease 0.22 LRK54_RS11785 VacJ family lipoprotein low > 59
Rhodanobacter denitrificans MT42 0.19 LRK55_RS14750 M48 family metalloprotease 0.22 LRK55_RS11510 VacJ family lipoprotein low > 63
Dyella japonica UNC79MFTsu3.2 0.18 ABZR86_RS00725 M48 family metalloprotease 0.21 ABZR86_RS11860 VacJ family lipoprotein low > 74
Rhodanobacter sp. FW510-T8 0.18 OKGIIK_03795 Putative beta-barrel assembly-enhancing protease 0.21 OKGIIK_12110 ABC transporter low > 53
Herbaspirillum seropedicae SmR1 0.18 HSERO_RS03305 peptidase M48 0.30 HSERO_RS20385 ABC transporter
Ralstonia sp. UNC404CL21Col 0.17 ABZR87_RS08020 M48 family metalloprotease 0.25 ABZR87_RS02540 VacJ family lipoprotein low > 80
Ralstonia solanacearum UW163 0.17 UW163_RS01485 peptidase M48 0.23 UW163_RS06730 ABC transporter
Ralstonia solanacearum IBSBF1503 0.17 RALBFv3_RS12125 peptidase M48 0.23 RALBFv3_RS06885 ABC transporter low > 76
Ralstonia solanacearum PSI07 0.17 RPSI07_RS21205 peptidase M48 0.23 RPSI07_RS10350 ABC transporter low > 81
Variovorax sp. OAS795 0.13 ABID97_RS02095 M48 family metalloprotease 0.21 ABID97_RS23200 VacJ family lipoprotein low > 91
Variovorax sp. SCN45 0.12 GFF5421 Peptidase M48, Ste24p precursor 0.21 GFF5337 Outer-membrane-phospholipid-binding lipoprotein MlaA low > 127
Acidovorax sp. GW101-3H11 0.11 Ac3H11_1239 Peptidase M48, Ste24p precursor 0.22 Ac3H11_4715 VacJ family lipoprotein low > 79
Phaeobacter inhibens DSM 17395 0.08 PGA1_c20310 putative metalloprotease 0.20 PGA1_c29360 VacJ-like lipoprotein low > 62

Not shown: 7 genomes with orthologs for HEPCGN_21000 only; 8 genomes with orthologs for HEPCGN_21730 only